Human/Mouse/Rat SOX2 Antibody

Catalog # Availability Size / Price Qty
MAB2018
MAB2018-SP
E‑Cadherin and SOX2 in BG01V Human Stem Cells.
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Product Details
Citations (138)
FAQs
Supplemental Products
Reviews (8)

Human/Mouse/Rat SOX2 Antibody Summary

Species Reactivity
Human, Mouse, Rat
Specificity
Detects human, mouse, and rat SOX2 in Western blots.
Source
Monoclonal Mouse IgG2A Clone # 245610
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
E. coli-derived recombinant human SOX2
Gly135-Met317
Accession # P48431
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
1 µg/mL
See below
Simple Western
4 µg/mL
See below
CyTOF-reported
Zunder, E.R. et al. (2015) Cell Stem Cell 16: 323. Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
 
Immunocytochemistry
8-25 µg/mL
See below
Intracellular Staining by Flow Cytometry
0.25 µg/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Examples

Immunocytochemistry E-Cadherin and SOX2 antibody in BG01V Human Stem Cells by Immunocytochemistry (ICC). View Larger

E‑Cadherin and SOX2 in BG01V Human Stem Cells. E-Cadherin and SOX2 were detected in BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human E-Cadherin Antigen Affinity-purified Polyclonal Antibody (Catalog # AF648) and 10 µg/mL Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for E-Cadherin using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and for SOX2 using the NorthernLights 493-conjugated Anti-Mouse Secondary Antibody (green; Catalog # NL009). Cells were counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Western Blot Detection of Human, Mouse, and Rat SOX2 antibody by Western Blot. View Larger

Detection of Human, Mouse, and Rat SOX2 by Western Blot. Western blot shows lysates of NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell line, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Immunocytochemistry SOX2 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC). View Larger

SOX2 in BG01V Human Embryonic Stem Cells. SOX2 was detected in immersion fixed BG01V human embryonic stem cells using Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow; Catalog # NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.

Intracellular Staining by Flow Cytometry Detection of SOX2 antibody in NTera-2 Human Cell Line antibody by Flow Cytometry. View Larger

Detection of SOX2 in NTera‑2 Human Cell Line by Flow Cytometry. NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.

Simple Western Detection of Human SOX2 antibody by Simple Western<SUP>TM</SUP>. View Larger

Detection of Human SOX2 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 50 kDa (as indicated) using 4 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SOX2

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-6).

References
  1. Graham, V. et al. (2003) Neuron 39:749.
  2. Avilion, A.A. et al. (2003) Genes Dev. 17:126.
  3. Kishi, M. et al. (2000) Development 127:791.
  4. Yuan, H. et al. (1995) Genes Dev. 9:2635.
  5. Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
  6. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Long Name
Transcription Factor SOX2
Entrez Gene IDs
6657 (Human)
Alternate Names
ANOP3; MCOPS3; MGC2413; SOX2; SRY (sex determining region Y)-box 2; SRY-related HMG-box gene 2; transcription factor SOX2; transcription factor SOX-2

Product Datasheets

Citations for Human/Mouse/Rat SOX2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

138 Citations: Showing 1 - 10
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  1. Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11
    Authors: W Zhu, YS Cheng, M Xu, A Farkhondeh, J Beers, J Zou, C Liu, K Baumgaerte, S Rodems, W Zheng
    Stem Cell Research, 2021;53(0):102366.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  2. Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation
    Authors: TP Silva, CA Pereira, AC Raposo, AR Oliveira, M Arez, JMS Cabral, I Milagre, M Carmo-Fons, STD Rocha
    Stem Cell Research, 2021;53(0):102364.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  3. Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G�>�A in the ACVR1 gene
    Authors: X Huang, A Roeder, R Li, J Beers, C Liu, J Zou, PB Yu, W Zheng
    Stem Cell Research, 2021;54(0):102424.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls
    Authors: L Ma, M Schmidt, EM Morrow
    Stem Cell Research, 2021;54(0):102435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  5. Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936�T�>�A) mutation in JAGGED-1
    Authors: BM Brooks, M Pradhan, YS Cheng, K Gorshkov, A Farkhondeh, CZ Chen, J Beers, C Liu, K Baumgaerte, S Rodems, W Zheng
    Stem Cell Research, 2021;54(0):102447.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  6. Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis
    Authors: MA Khuu, T Nallamothu, CI Castro-Riv, A Arias-Cavi, CC Szujewski, AJ Garcia Iii
    Scientific Reports, 2021;11(1):6005.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1
    Authors: BM Brooks, CD Yeh, J Beers, C Liu, YS Cheng, K Gorshkov, J Zou, W Zheng, CZ Chen
    Stem Cell Research, 2021;53(0):102387.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  8. Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis
    Authors: L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, L Manzoni, L Ottoboni, L Feo, A Quattrini, E Mastrangel, L Sorrentino, E Scalone, G Comi, L Marinelli, N Riva, M Milani, P Seneci, G Martino
    Nat Commun, 2020;11(1):3848.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics
    Authors: AA Zalenski, S Majumder, K De, M Venere
    Sci Rep, 2020;10(1):13946.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  10. Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals
    Authors: X Xu, M Pradhan, M Xu, YS Cheng, J Beers, KL Linask, Y Lin, W Zheng, J Zou
    Stem Cell Res, 2020;49(0):102011.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome
    Authors: SR Sripathy, Y Wang, RL Moses, A Fatemi, DA Batista, BJ Maher
    Stem Cell Res, 2020;48(0):102001.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  12. Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties
    Authors: V Pasquale, G Ducci, G Campioni, A Ventrici, C Assalini, S Busti, M Vanoni, R Vago, E Sacco
    Cells, 2020;9(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  13. Generation of an induced pluripotent stem cell line from an Alstr�m Syndrome patient with ALMS1 mutation (c.3902C�>�A, c.6436C�>�T) and a gene correction isogenic iPSC line
    Authors: X Ji, Q Tang, C Tang, Z Wu, L Ma, X Guo, G Cheng, Y Chen, T Yang, M Xiong, W Zhou
    Stem Cell Res, 2020;49(0):102089.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  14. Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis
    Authors: F Pecori, Y Akimoto, H Hanamatsu, JI Furukawa, Y Shinohara, Y Ikehara, S Nishihara
    J. Cell. Sci., 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  15. Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy
    Authors: H Hengel, C Bosso-Lefè, G Grady, E Szenker-Ra, H Li, S Pierce, É Lebigot, TT Tan, MY Eio, G Narayanan, KH Utami, M Yau, N Handal, W Deigendesc, R Keimer, HM Marzouqa, M Gunay-Aygu, MJ Muriello, H Verhelst, S Weckhuysen, S Mahida, S Naidu, TG Thomas, JY Lim, ES Tan, D Haye, MAAP Willemsen, R Oegema, WG Mitchell, TM Pierson, MV Andrews, MC Willing, LH Rodan, TS Barakat, M van Slegte, RH Gavrilova, D Martinelli, T Gilboa, AM Tamim, MO Hashem, MD AlSayed, MM Abdulrahim, M Al-Owain, A Awaji, AAH Mahmoud, EA Faqeih, AA Asmari, SM Algain, LA Jad, HM Aldhalaan, I Helbig, DA Koolen, A Riess, I Kraegeloh-, P Bauer, S Gulsuner, H Stamberger, AYJ Ng, S Tang, S Tohari, B Keren, LE Schultz-Ro, EW Klee, S Barresi, M Tartaglia, H Mor-Shaked, S Maddirevul, A Begtrup, A Telegrafi, R Pfundt, R Schüle, B Ciruna, C Bonnard, MA Pouladi, JC Stewart, A Claridge-C, DJ Lefeber, FS Alkuraya, AS Mathuru, B Venkatesh, JJ Barycki, MA Simpson, SS Jamuar, L Schöls, B Reversade
    Nat Commun, 2020;11(1):595.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  16. An induced pluripotent stem cell line (TRNDi001-D) from a Niemann-Pick disease type C1 (NPC1) patient carrying a homozygous p. I1061T (c. 3182T>C) mutation in the NPC1 gene
    Authors: R Li, M Pradhan, M Xu, A Roeder, J Beers, J Zou, C Liu, FD Porter, W Zheng
    Stem Cell Res, 2020;44(0):101737.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  17. Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells
    Authors: R Kitajima, R Nakai, T Imamura, T Kameda, D Kozuka, H Hirai, H Ito, H Imai, M Imamura
    Stem Cell Res, 2020;44(0):101749.
    Species: Pan troglodytes (Chimpanzee)
    Sample Types: Whole Cells
    Applications: ICC
  18. Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
    Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
    Cell Rep, 2020;31(5):107599.
    Species: Human
    Sample Types:
    Applications: IF
  19. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation
    Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2019;37(0):101437.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  20. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner
    Authors: L Zurkirchen, S Varum, S Giger, A Klug, J Häusel, R Bossart, M Zemke, C Cantù, ZK Atak, N Zamboni, K Basler, L Sommer
    Nat Commun, 2019;10(1):2192.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  21. Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene
    Authors: J Hong, M Xu, R Li, YS Cheng, J Kouznetsov, J Beers, C Liu, J Zou, W Zheng
    Stem Cell Res, 2019;37(0):101451.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  22. The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line
    Authors: S Howden, H Hosseini F, A Motazedian, AG Elefanty, EG Stanley, SR Lamandé, JF Bateman
    Stem Cell Res, 2019;38(0):101453.
    Species: Human
    Sample Types: Whole Cells
  23. Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene
    Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019;37(0):101436.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  24. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation
    Authors: M Mura, YK Lee, F Pisano, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2019;37(0):101431.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  25. Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy
    Authors: T Klein, K Klug, L Henkel, CK Kwok, F Edenhofer, E Klopocki, I Kurth, N Üçeyler
    Stem Cell Res, 2019;35(0):101396.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  26. User-defined morphogen patterning for directing human cell fate stratification
    Authors: MC Regier, JJ Tokar, JW Warrick, L Pabon, E Berthier, DJ Beebe, KR Stevens
    Sci Rep, 2019;9(1):6433.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  27. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene
    Authors: M Mura, F Pisano, M Stefanello, M Ginevrino, M Boni, F Calabrò, L Crotti, EM Valente, PJ Schwartz, PA Brink, M Gnecchi
    Stem Cell Res, 2019;36(0):101416.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  28. Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids
    Authors: H Kim, HJ Park, H Choi, Y Chang, H Park, J Shin, J Kim, CJ Lengner, YK Lee, J Kim
    Stem Cell Reports, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  29. A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene
    Authors: YS Cheng, R Li, A Baskfield, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019;37(0):101435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  30. Single-cell transcriptomic analysis of mouse neocortical development
    Authors: L Loo, JM Simon, L Xing, ES McCoy, JK Niehaus, J Guo, ES Anton, MJ Zylka
    Nat Commun, 2019;10(1):134.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma
    Authors: M Sherman-Sa, H Onallah, A Holth, R Reich, B Davidson
    Gynecol. Oncol., 2019;0(0):.
    Species: Human
    Sample Types: Tumor Tissue Fluid
    Applications: ICC
  32. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death
    Authors: MA Ajmone-Cat, A Onori, C Toselli, E Stronati, M Morlando, I Bozzoni, E Monni, Z Kokaia, G Lupo, L Minghetti, S Biagioni, E Cacci
    Sci Rep, 2019;9(1):4572.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  33. CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons
    Authors: C Calatayud, G Carola, I Fernández-, M Valtorta, S Jiménez-De, M Díaz, J Soriano-Fr, G Cappellett, J García-San, Á Raya, A Consiglio
    Sci Rep, 2019;9(1):6811.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  34. A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma
    Authors: BW Stringer, BW Day, RCJ D'Souza, PR Jamieson, KS Ensbey, ZC Bruce, YC Lim, K Goasdoué, C Offenhäuse, S Akgül, S Allan, T Robertson, P Lucas, G Tollesson, S Campbell, C Winter, H Do, A Dobrovic, PL Inglis, RL Jeffree, TG Johns, AW Boyd
    Sci Rep, 2019;9(1):4902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  35. An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene
    Authors: A Baskfield, R Li, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019;38(0):101461.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  36. Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness
    Authors: SFB Fadhlullah, NBA Halim, JYT Yeo, RLY Ho, P Um, BT Ang, C Tang, WH Ng, DM Virshup, IAW Ho
    Oncogene, 2019;38(27):5367-5380.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  37. The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer
    Authors: S Melissarid, E Wiechec, M Magan, MV Jain, MK Chung, L Farnebo, K Roberg
    Cancer Cell Int., 2019;19(0):16.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  38. An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene
    Authors: W Huang, M Xu, R Li, A Baskfield, J Kouznetsov, J Beers, J Zou, C Liu, W Zheng
    Stem Cell Res, 2019;37(0):101427.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  39. Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures
    Authors: T Hyvärinen, A Hyysalo, FE Kapucu, L Aarnos, A Vinogradov, SJ Eglen, L Ylä-Outine, S Narkilahti
    Sci Rep, 2019;9(1):17125.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  40. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1
    Authors: M Mura, F Bastaroli, M Corli, M Ginevrino, F Calabrò, M Boni, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
    Stem Cell Res, 2019;42(0):101658.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  41. Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells
    Authors: A Stubb, C Guzmán, E Närvä, J Aaron, TL Chew, M Saari, M Miihkinen, G Jacquemet, J Ivaska
    Nat Commun, 2019;10(1):4756.
    Species: Human
    Sample Types: Whole Cells
    Applications: Western Blot
  42. Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs
    Authors: E Grall, V Gourain, A Naïr, E Martin, MC Birling, JN Freund, I Duluc
    Cell Death Dis, 2019;10(11):812.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  43. ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation
    Authors: NM Peñaranda-, C Meijer, Y Liang, BM Dijkstra, R Aguirre-Ga, WFA den Dunnen, FAE Kruyt
    Cell Death Dis, 2019;10(10):690.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  44. An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene
    Authors: S Yang, YS Cheng, R Li, M Pradhan, J Hong, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
    Stem Cell Res, 2019;39(0):101496.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  45. Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene
    Authors: R Li, A Baskfield, J Beers, J Zou, C Liu, CJ Alméciga-D, W Zheng
    Stem Cell Res, 2019;36(0):101408.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  46. Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas
    Authors: C Aaberg-Jes, MD Sørensen, ALSA Matos, JM Moreira, N Brünner, A Knudsen, BW Kristensen
    BMC Cancer, 2018;18(1):270.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  47. Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient
    Authors: S Vallejo-Di, A Fleischer, JM Martín-Fer, A Sánchez-Gi, D Bachiller
    Stem Cell Res, 2018;33(0):180-184.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  48. Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene
    Authors: R Li, A Baskfield, Y Lin, J Beers, J Zou, C Liu, F Jaffré, AE Roberts, EA Ottinger, MI Kontaridis, W Zheng
    Stem Cell Res, 2018;34(0):101374.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  49. Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells
    Authors: M Jeong, M O'Reilly, NK Kirkwood, J Al-Aama, M Lako, CJ Kros, L Armstrong
    Cell Death Dis, 2018;9(9):922.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  50. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708?G?>?C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene
    Authors: T Klein, K Günther, CK Kwok, F Edenhofer, N Üçeyler
    Stem Cell Res, 2018;31(0):222-226.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  51. Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation
    Authors: CP Cui, Y Zhang, C Wang, F Yuan, H Li, Y Yao, Y Chen, C Li, W Wei, CH Liu, F He, Y Liu, L Zhang
    Nat Commun, 2018;9(1):4648.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  52. Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene
    Authors: R Li, M Pradhan, M Xu, A Baskfield, A Farkhondeh, YS Cheng, J Beers, J Zou, C Liu, M Might, S Rodems, W Zheng
    Stem Cell Res, 2018;34(0):101362.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  53. The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo
    Authors: SU Vay, LJ Flitsch, M Rabenstein, R Rogall, S Blaschke, J Kleinhaus, N Reinert, A Bach, GR Fink, M Schroeter, MA Rueger
    J Neuroinflammation, 2018;15(1):226.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  54. Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata)
    Authors: R Nakai, M Ohnuki, K Kuroki, H Ito, H Hirai, R Kitajima, T Fujimoto, M Nakagawa, W Enard, M Imamura
    Sci Rep, 2018;8(1):12187.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: ICC
  55. FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury
    Authors: A Alastrue-A, FJ Rodriguez-, EL Mocholi, F De Giorgio, S Erceg, V Moreno-Man
    Int J Mol Sci, 2018;19(1):.
    Species: Rat
    Sample Types: Cell Lysates
    Applications: Western Blot
  56. Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation
    Authors: NS Corsini, AM Peer, P Moeseneder, M Roiuk, TR Burkard, HC Theussl, I Moll, JA Knoblich
    Cell Stem Cell, 2018;22(4):543-558.e12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  57. TFAP2C regulates transcription in human naive pluripotency by opening enhancers
    Authors: WA Pastor, W Liu, D Chen, J Ho, R Kim, TJ Hunt, A Lukianchik, X Liu, JM Polo, SE Jacobsen, AT Clark
    Nat. Cell Biol., 2018;20(5):553-564.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  58. Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease
    Authors: JY Lee, SH Han, MH Park, B Baek, IS Song, MK Choi, Y Takuwa, H Ryu, SH Kim, X He, EH Schuchman, JS Bae, HK Jin
    Nat Commun, 2018;9(1):1479.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  59. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1
    Authors: M Mura, M Ginevrino, R Zappatore, F Pisano, M Boni, S Castellett, L Crotti, EM Valente, PJ Schwartz, M Gnecchi
    Stem Cell Res, 2018;29(0):170-173.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  60. Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
    Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
    Front Cell Dev Biol, 2018;6(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  61. Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein
    Authors: G V?fély, T Berecz, E Szabó, K Szebényi, E Hathy, TI Orbán, B Sarkadi, L Homolya, MC Marchetto, JM Réthelyi, Á Apáti
    Mol. Cell. Neurosci., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  62. Differential response in novel stem cell niches of the brain following cervical spinal cord injury and traumatic brain injury
    Authors: A Falnikar, J Stratton, R Lin, CE Andrews, A Tyburski, VA Trovillion, C Gottschalk, B Ghosh, L Iacovitti, MB Elliott, AC Lepore
    J. Neurotrauma, 2018;0(0):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  63. Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
    Authors: A Yachie-Kin, K Onishi, J Ostblom, MA Langley, E Posfai, J Rossant, PW Zandstra
    Mol. Syst. Biol., 2018;14(1):e7952.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  64. Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity
    Authors: D Poppe, J Doerr, M Schneider, R Wilkens, JA Steinbeck, J Ladewig, A Tam, DE Paschon, PD Gregory, A Reik, CE Müller, P Koch, O Brüstle
    Stem Cells Transl Med, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  65. The non-canonical Wnt-PCP pathway shapes the caudal neural plate
    Authors: B López-Esco, JM Caro-Vega, DS Vijayragha, TF Plageman, JA Sanchez-Al, RC Moreno, D Savery, J Márquez-Ri, LA Davidson, P Ybot-Gonzá
    Development, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  66. Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation
    Authors: S Kwak, TW Kim, BH Kang, JH Kim, JS Lee, HT Lee, IY Hwang, J Shin, JH Lee, EJ Cho, HD Youn
    Nucleic Acids Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  67. Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation
    Authors: M Naumann, A Pal, A Goswami, X Lojewski, J Japtok, A Vehlow, M Naujock, R Günther, M Jin, N Stanslowsk, P Reinhardt, J Sternecker, M Frickenhau, F Pan-Montoj, E Storkebaum, I Poser, A Freischmid, JH Weishaupt, K Holzmann, D Troost, AC Ludolph, TM Boeckers, S Liebau, S Petri, N Cordes, AA Hyman, F Wegner, SW Grill, J Weis, A Storch, A Hermann
    Nat Commun, 2018;9(1):335.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  68. INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice
    Authors: O Le, L Palacio, G Bernier, I Batinic-Ha, G Hickson, C Beauséjour
    Stem Cell Reports, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  69. Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene
    Authors: M Mura, YK Lee, M Ginevrino, R Zappatore, F Pisano, M Boni, F Dagradi, L Crotti, EM Valente, PJ Schwartz, HF Tse, M Gnecchi
    Stem Cell Res, 2018;29(0):157-161.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  70. Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel
    Authors: X Gao, JJ Yourick, RL Sprando
    Stem Cell Res, 2018;31(0):193-196.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  71. Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo
    Authors: SS Jensen, SA Petterson, B Halle, C Aaberg-Jes, BW Kristensen
    BMC Cancer, 2017;17(1):178.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  72. Laminin ?5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro
    Authors: A Hyysalo, M Ristola, ME Mäkinen, S Häyrynen, M Nykter, S Narkilahti
    Stem Cell Res, 2017;24(0):118-127.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  73. Nicotinamide metabolism regulates glioblastoma stem cell maintenance
    Authors: J Jung, LJY Kim, X Wang, Q Wu, T Sanvoranar, CG Hubert, BC Prager, LC Wallace, X Jin, SC Mack, JN Rich
    JCI Insight, 2017;2(10):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  74. Cancer stem-like cells can be induced through dedifferentiation under hypoxic conditions in glioma, hepatoma and lung cancer
    Authors: P Wang, WW Wan, SL Xiong, H Feng, N Wu
    Cell Death Discov, 2017;3(0):16105.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  75. Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding
    Authors: S Falk, S Bugeon, J Ninkovic, GA Pilz, MP Postiglion, H Cremer, JA Knoblich, M Götz
    Neuron, 2017;93(4):777-791.e3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  76. HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia
    Authors: P Wang, C Lan, S Xiong, X Zhao, Y Shan, R Hu, W Wan, S Yu, B Liao, G Li, J Wang, D Zou, B Chen, H Feng, N Wu
    Oncotarget, 2017;8(17):28074-28092.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  77. Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
    Authors: X Wang, K Yang, Q Xie, Q Wu, SC Mack, Y Shi, LJ Kim, BC Prager, WA Flavahan, X Liu, M Singer, CG Hubert, TE Miller, W Zhou, Z Huang, X Fang, A Regev, ML Suvà, TH Hwang, JW Locasale, S Bao, JN Rich
    Nat. Neurosci, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  78. A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases
    Authors: I Karakikes, V Termglinch, DA Cepeda, J Lee, S Diecke, A Hendel, I Itzhaki, M Ameen, R Shrestha, H Wu, N Ma, NY Shao, T Seeger, NA Woo, KD Wilson, E Matsa, MH Porteus, V Sebastiano, JC Wu
    Circ. Res, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  79. Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix
    Authors: G Kaufman, D Skrtic
    Tissue Cell, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  80. A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity
    Authors: G Riddick, S Kotliarova, V Rodriguez, HS Kim, A Linkous, AJ Storaska, S Ahn, J Walling, G Belova, HA Fine
    Sci Rep, 2017;7(0):43605.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  81. Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa
    Authors: TP Sharma, LA Wiley, SS Whitmore, KR Anfinson, CM Cranston, DJ Oppedal, HT Daggett, RF Mullins, BA Tucker, EM Stone
    Stem Cell Res, 2017;21(0):58-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  82. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells
    Authors: T Yamashita, Y Miyamoto, Y Bando, T Ono, S Kobayashi, A Doi, T Araki, Y Kato, T Shirakawa, Y Suzuki, J Yamauchi, S Yoshida, N Sato
    PLoS ONE, 2017;12(2):e0171947.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  83. Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug
    Authors: M Okada, H Takeda, H Sakaki, K Kuramoto, S Suzuki, T Sanomachi, K Togashi, S Seino, C Kitanaka
    Oncotarget, 2017;8(55):94872-94882.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  84. Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
    Authors: AG Alvarado, PS Thiagaraja, EE Mulkearns-, DJ Silver, JS Hale, TJ Alban, SM Turaga, A Jarrar, O Reizes, MS Longworth, MA Vogelbaum, JD Lathia
    Cell Stem Cell, 2017;20(4):450-461.e4.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  85. Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
    Authors: R Bayat Mokh, N Baluch, M Ka Hon Tsu, S Kumar, T S Homayoun, K Aitken, B Das, S Baruchel, H Yeger
    BMC Cancer, 2017;17(1):156.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  86. RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells
    Authors: HO King, T Brend, HL Payne, A Wright, TA Ward, K Patel, T Egnuni, LF Stead, A Patel, H Wurdak, SC Short
    Stem Cell Reports, 2017;8(1):125-139.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  87. FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1
    Authors: K Hirano, M Namihira
    FEBS Open Bio, 2017;7(12):1932-1942.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  88. Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9
    Authors: Y Xu, Y Wu, D Guo, G Gao, K Lai, F Yang, K Wang, H Wu, L Lai, J Li, K Xu, YX Li
    Stem Cell Res, 2017;22(0):29-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  89. Enhancing the Three-Dimensional Structure of Adherent Gingival Fibroblasts and Spheroids via a Fibrous Protein-Based Hydrogel Cover
    Cells Tissues Organs (Print), 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  90. Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells
    Authors: Annabelle Congras
    Sci Rep, 2016;6(0):27059.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: IHC
  91. SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
    PLoS Biol., 2016;14(11):e1002581.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  92. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness
    Sci Rep, 2016;6(0):30742.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  93. Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
    Stem Cells, 2016;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  94. Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9
    Stem Cell Res, 2016;17(2):441-443.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  95. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A
    Stem Cells Transl Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  96. ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA
    Oncogene, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  97. Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype
    PLoS ONE, 2016;11(5):e0155106.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  98. Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9
    Stem Cell Res, 2016;17(2):430-432.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC-Fr
  99. EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties.
    Authors: Miao, H, Gale, N W, Guo, H, Qian, J, Petty, A, Kaspar, J, Murphy, A J, Valenzuela, D M, Yancopoulos, G, Hambardzumyan, D, Lathia, J D, Rich, J N, Lee, J, Wang, B
    Oncogene, 2015;34(5):558-67.
  100. Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation.
    Authors: Garriock R, Chalamalasetty R, Kennedy M, Canizales L, Lewandoski M, Yamaguchi T
    Development, 2015;142(9):1628-38.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  101. SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance.
    Authors: Kim, Dohoon, Fiske, Brian P, Birsoy, Kivanc, Freinkman, Elizavet, Kami, Kenjiro, Possemato, Richard, Chudnovsky, Yakov, Pacold, Michael, Chen, Walter W, Cantor, Jason R, Shelton, Laura M, Gui, Dan Y, Kwon, Manjae, Ramkissoon, Shakti H, Ligon, Keith L, Kang, Seong Wo, Snuderl, Matija, Vander Heiden, Matthew, Sabatini, David M
    Nature, 2015;520(7547):363-7.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  102. Zrf1 is required to establish and maintain neural progenitor identity.
    Authors: Aloia L, Di Stefano B, Sessa A, Morey L, Santanach A, Gutierrez A, Cozzuto L, Benitah S, Graf T, Broccoli V, Di Croce L
    Genes Dev, 2014;28(2):182-97.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  103. Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency.
    Authors: Onishi K, Tonge P, Nagy A, Zandstra P
    Stem Cell Reports, 2014;3(1):156-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  104. Isolation of cancer stem cells from three human glioblastoma cell lines: characterization of two selected clones.
    Authors: Iacopino F, Angelucci C, Piacentini R, Biamonte F, Mangiola A, Maira G, Grassi C, Sica G
    PLoS ONE, 2014;9(8):e105166.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  105. Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4.
    Authors: Volonte A, Di Tomaso T, Spinelli M, Todaro M, Sanvito F, Albarello L, Bissolati M, Ghirardelli L, Orsenigo E, Ferrone S, Doglioni C, Stassi G, Dellabona P, Staudacher C, Parmiani G, Maccalli C
    J Immunol, 2014;192(1):523-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  106. Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape.
    Authors: Sherwood, Richard, Hashimoto, Tatsunor, O'Donnell, Charles, Lewis, Sophia, Barkal, Amira A, van Hoff, John Pet, Karun, Vivek, Jaakkola, Tommi, Gifford, David K
    Nat Biotechnol, 2014;32(2):171-8.
  107. A single-cell and feeder-free culture system for monkey embryonic stem cells.
    Authors: Ono T, Suzuki Y, Kato Y, Fujita R, Araki T, Yamashita T, Kato H, Torii R, Sato N
    PLoS ONE, 2014;9(2):e88346.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: ICC
  108. Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro.
    Authors: Sousa-Ferreira L, Aveleira C, Botelho M, Alvaro A, Pereira de Almeida L, Cavadas C
    PLoS ONE, 2014;9(3):e88917.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  109. Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells.
    Authors: Izumikawa, Tomomi, Sato, Ban, Kitagawa, Hiroshi
    Sci Rep, 2014;4(0):3701.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  110. Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex.
    Authors: Minamide, Ryohei, Fujiwara, Kazushir, Hasegawa, Koichi, Yoshikawa, Kazuaki
    PLoS ONE, 2014;9(1):e84460.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  111. The subventricular zone is able to respond to a demyelinating lesion after localized radiation.
    Authors: Capilla-Gonzalez V, Guerrero-Cazares H, Bonsu J, Gonzalez-Perez O, Achanta P, Wong J, Garcia-Verdugo J, Quinones-Hinojosa A
    Stem Cells, 2014;32(1):59-69.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  112. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
    Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
    Genes Dev, 2014;28(10):1085-100.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  113. Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus.
    Authors: Haan, Niels, Goodman, Timothy, Najdi-Samiei, Alaleh, Stratford, Christin, Rice, Ritva, El Agha, Elie, Bellusci, Saverio, Hajihosseini, Mohammad
    J Neurosci, 2013;33(14):6170-80.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  114. Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells.
    Authors: Najm, Fadi J, Lager, Angela M, Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V, Factor, Daniel C, Karl, Robert T, Maeda, Tadao, Miller, Robert H, Tesar, Paul J
    Nat Biotechnol, 2013;31(5):426-33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  115. Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb.
    Authors: Li, Tan, Pan, Yung-Wei, Wang, Wenbin, Abel, Glen, Zou, Junhui, Xu, Lihong, Storm, Daniel R, Xia, Zhengui
    PLoS ONE, 2013;8(4):e61948.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  116. Embryonic stem cell-based modeling of tau pathology in human neurons.
    Authors: Mertens J, Stuber K, Poppe D, Doerr J, Ladewig J, Brustle O, Koch P
    Am J Pathol, 2013;182(5):1769-79.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  117. REST regulates oncogenic properties of glioblastoma stem cells.
    Authors: Kamal MM, Sathyan P, Singh SK, Zinn PO, Marisetty AL, Liang S, Gumin J, El-Mesallamy HO, Suki D, Colman H, Fuller GN, Lang FF, Majumder S
    Stem Cells, 2012;30(3):405-14.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  118. Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.
    Authors: Hayashi, Ryuhei, Ishikawa, Yuki, Ito, Miyuki, Kageyama, Tomofumi, Takashiba, Kuniko, Fujioka, Tsuyoshi, Tsujikawa, Motokazu, Miyoshi, Hiroyuki, Yamato, Masayuki, Nakamura, Yukio, Nishida, Kohji
    PLoS ONE, 2012;7(9):e45435.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  119. Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells.
    Authors: Lathia JD, Gallagher J, Myers JT
    PLoS ONE, 2011;6(9):e24807.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  120. Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects.
    Authors: Mahar I, Tan S, Davoli MA, Dominguez-Lopez S, Qiang C, Rachalski A, Turecki G, Mechawar N
    PLoS ONE, 2011;6(10):e26610.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  121. Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel.
    Authors: Hibino N, Villalona G, Pietris N
    FASEB J., 2011;25(8):2731-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  122. Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells.
    Authors: West FD, Mumaw JL, Gallegos-Cardenas A, Young A, Stice SL
    Stem Cells Dev., 2011;20(6):1079-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  123. Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells.
    Authors: Kambal A, Mitchell G, Cary W, Gruenloh W, Jung Y, Kalomoiris S, Nacey C, McGee J, Lindsey M, Fury B, Bauer G, Nolta JA, Anderson JS
    Mol. Ther., 2011;19(3):584-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  124. Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors.
    Authors: Liu A, Cheng L, Du J, Peng Y, Allan RW, Wei L, Li J, Cao D
    Am. J. Surg. Pathol., 2010;34(5):697-706.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  125. Epigenetic changes to human umbilical cord blood cells cultured with three proteins indicate partial reprogramming to a pluripotent state.
    Authors: Wong CJ, Casper RF, Rogers IM
    Exp. Cell Res., 2010;316(6):927-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  126. Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography.
    Authors: Rueger MA, Backes H, Walberer M, Neumaier B, Ullrich R, Simard ML, Emig B, Fink GR, Hoehn M, Graf R, Schroeter M
    J. Neurosci., 2010;30(18):6454-60.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC
  127. Paternal recognition of adult offspring mediated by newly generated CNS neurons.
    Authors: Mak GK, Weiss S,
    Nat. Neurosci., 2010;13(6):753-8.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  128. The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used.
    J. Cell. Biochem., 2009;106(5):867-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  129. Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells.
    Authors: Neganova I, Zhang X, Atkinson S, Lako M
    Oncogene, 2009;28(1):20-30.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  130. Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation.
    Authors: Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, Ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP
    J. Neurosci., 2008;28(51):13978-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  131. Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures.
    Authors: Rao RC, Boyd J, Padmanabhan R, Chenoweth JG, McKay RD
    Stem Cells, 2008;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  132. TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal.
    Authors: Varelas X, Sakuma R, Samavarchi-Tehrani P, Peerani R, Rao BM, Dembowy J, Yaffe MB, Zandstra PW, Wrana JL
    Nat. Cell Biol., 2008;10(7):837-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  133. Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1.
    Authors: Hattori Y, Ohta S, Hamada K, Yamada-Okabe H, Kanemura Y, Matsuzaki Y, Okano H, Kawakami Y, Toda M
    Biochem. Biophys. Res. Commun., 2007;364(4):737-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  134. Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue.
    Authors: Shin S, Sun Y, Liu Y, Khaner H, Svant S, Cai J, Xu QX, Davidson BP, Stice SL, Smith AK, Goldman SA, Reubinoff BE, Zhan M, Rao MS, Chesnut JD
    Stem Cells, 2007;25(5):1298-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  135. Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy.
    Authors: Schmitz M, Temme A, Senner V, Ebner R, Schwind S, Stevanovic S, Wehner R, Schackert G, Schackert HK, Fussel M, Bachmann M, Rieber EP, Weigle B
    Br. J. Cancer, 2007;96(8):1293-301.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  136. Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage.
    Authors: Pankratz MT, Li XJ, Lavaute TM, Lyons EA, Chen X, Zhang SC
    Stem Cells, 2007;25(6):1511-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  137. Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.
    Authors: Gunther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K
    Oncogene, 2007;27(20):2897-909.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  138. Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats.
    Authors: Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O
    Stroke, 2006;37(9):2361-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: ICC

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Reviews for Human/Mouse/Rat SOX2 Antibody

Average Rating: 4.5 (Based on 8 Reviews)

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Human/Mouse/Rat SOX2 Antibody
By Anonymous on 08/06/2021
Application: ICC/IF Sample Tested: glioblastoma cells Species: Human

On the photo SOX2 is red, nuclear DAPI is blue.


Human/Mouse/Rat SOX2 Antibody
By Anonymous on 10/18/2018
Application: ICC/IF Sample Tested: iPS2 human induced pluripotent stem cells Species: Human

Cells: human induced pluripotent stem cells
Primary antibody: anti-human SOX2 (1:200), O/N incubation at 4 degrees
Secondary antibody: anti-mouse AF488


Human/Mouse/Rat SOX2 Antibody
By Anonymous on 02/16/2017
Application: IHC Sample Tested: Brain (forebrain) Species: Mouse

Red: sox2. Green: ki67. Blue: DAPI. Postnatal day 7 sub-ventricular zone. 2% PFA fixed. Heat-mediated antigen retrieval. Blocked with 10% donkey serum, 0.5% Triton in PBS for 1h. Dilution 1:100.


Human/Mouse/Rat SOX2 Antibody
By Anonymous on 02/03/2017
Application: ICC/IF Sample Tested: Neural progenitor cells Species: Human

Human/Mouse SOX2 Antibody
By Anonymous on 12/15/2016
Application: ICC/IF Sample Tested: Induced pluripotent stem cells Species: Human

I used this antibody to test Sox2 expression in iPS cells derived from fibroblasts of Sanfilippo syndrome C patients.


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: WB Sample Tested: Human cells Species: Human

Specificity: Specific
Sensitivity: Sensitive
Buffer: 5% BSA in TBST
Dilution: 1/1000


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: ICC/IF Sample Tested: human NSC Species: Human

Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100


Human/Mouse SOX2 Antibody
By Anonymous on 10/26/2015
Application: ICC/IF Sample Tested: human fibroblast and neural stem cells Species: Human

Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100