Human MS4A1/CD20 Alexa Fluor® 700-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Flow Cytometry View Larger

Detection of MS4A1/CD20 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD19 PE‑conjugated Monoclonal Antibody (Catalog # FAB4867P) and either (A) Mouse Anti-Human MS4A1/CD20 Alexa Fluor® 700‑conjugated Monoclonal Antibody (Catalog # FAB4225N) or (B) Mouse IgG₁ Alexa Fluor 700 Isotype Control (Catalog # IC002N). View our protocol for Staining Membrane-associated Proteins.

Preparation and Storage

Background: CD20

CD20 is a 297 amino acid (aa), non-glycosylated, four-transmembrane protein that is the founding member of the MS4A tetraspanning protein family. It is expressed on pre-B, naïve and mature B lymphocytes and B-cell lymphomas. CD20 is associated with lipid rafts upon crosslinking, and appears to play a role in regulation of ion influx. The one extracellular segment of 48 aa shows 65% aa identity between human and mouse CD20.

Product Datasheets

Related Research Areas

• Acute Lymphoblastic Leukemia
• B Cell Activation
• B Cell Markers
• Cancer Stem Cell Markers
• Conventional/Classical Dendritic Cells
• Inflammatory/Monocyte-derived Dendritic Cells
• Langerhans and Dermal Dendritic Cells
• Lymphoid Lineage Markers
• Lymphoma
• Plasmacytoid Dendritic Cells