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Human MYH6 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB8979T Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB8979T-100UG

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Human MYH6 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human MYH6. The peptide immunogen sequence represents a region specific to MYH6 and not present in other MYH isoforms.
Source
Monoclonal Mouse IgG1 Clone # 940344
Purification
Protein A or G purified
Immunogen
Human MYH6 peptide
Accession # P13533
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunohistochemistry
Optimal dilution of this antibody should be experimentally determined.
 
Immunocytochemistry
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: MYH6

The MYH6 gene encodes the alpha chain of cardiac myosin, a muscle motor protein with two regions that bind actin at aa 657-679 and 759-773. Defects in this gene cause atrial septal defect 3, hypertrophic cardiac myopathy and sick sinus syndrome. MYH6 participates in embryonic and adult heart development and muscle contraction.  In adult heart, the beta chain isoform predominates in the ventricular tissue, while both isoforms are found in variable proportions in atrial tissue.  Force development is much faster in atrial tissue and ATP consumption is much higher.

Long Name
Myosin Heavy Chain 6, Cardiac Muscle, Alpha
Entrez Gene IDs
4624 (Human); 17888 (Mouse); 29556 (Rat)
Alternate Names
alpha-MHC; ASD3; cardiomyopathy; CMD1EE; CMH14; Hypertrophic 1; MYH6; MYHC; MYHCA; MyHC-Alpha; Myosin Heavy Chain 6; Myosin Heavy Chain, Cardiac Muscle Alpha Isoform; Myosin, Heavy Chain 6, Cardiac Muscle, Alpha; Myosin, Heavy Polypeptide 6, Cardiac Muscle, Alpha (Cardiomyopathy, Hypertrophic 1); Myosin-6; SSS3

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