Detection of NKG2C/CD159c in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human NCAM‑1/CD56 PE‑conjugated Monoclonal Antibody (Catalog # FAB2408P) and either (A) Mouse Anti-Human NKG2C/CD159c Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB138R) or (B) Mouse IgG1 Alexa Fluor 647 Isotype Control (Catalog # IC002R). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
NKG2C is a type II transmembrane glycoprotein member of the NKG2 family of molecules. It is expressed by CD4+ and CD8+ T cells, and is known to appear on NK cells. On the cell surface, NKG2C forma a covalent heterodimer with CD94. In the configuration, it recognizes HLA-E determinants on target cells, inducing activation and degranulation of the expressing lymphocyte. The human and mouse extracellular domains have 40% amino acid sequence identity.
Natural Killer G2C
Entrez Gene IDs:
CD159 antigen-like family member C; CD159c antigen; CD159c; killer cell lectin-like receptor subfamily C, member 2; KLRC2; MGC138244; NK cell receptor C; NKG2-C type II integral membrane protein; NKG2-C; NKG2CNKG2-C-activating NK receptor
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