Human PI 3-Kinase p110 gamma (NP_002640.2) VersaClone cDNA

R&D Systems | Catalog # RDC3759

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Key Product Details

Species

Human

Accession Number

NP_002640.2

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: PI 3-Kinase p110 gamma

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Long Name

Protein Tyrosine Phosphatase 1G

Alternate Names

p120-PI3K, PI 3Kinase p110 gamma, PI3CG, PI3K-gamma, PIK3CG

Entrez Gene IDs

5294 (Human); 30955 (Mouse); 298947 (Rat)

Gene Symbol

PIK3CG

UniProt

NP_002640.2

Additional PI 3-Kinase p110 gamma Products

Product Documents for Human PI 3-Kinase p110 gamma (NP_002640.2) VersaClone cDNA

Certificate of Analysis

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Product Specific Notices for Human PI 3-Kinase p110 gamma (NP_002640.2) VersaClone cDNA

For research use only

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