Human Serum TIM-1/KIM-1/HAVCR Quantikine ELISA Kit Summary
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
|Intra-Assay Precision||Inter-Assay Precision|
The recovery of human TIM-1 spiked to levels throughout the range of the assay was evaluated.
|Sample Type||Average % Recovery||Range %|
|Cell Culture Media (n=4)||94||89-102|
|EDTA Plasma (n=4)||93||80-108|
|Heparin Plasma (n=4)||91||81-104|
Human TIM-1/KIM-1/HAVCR ELISA Standard Curve
Preparation and Storage
TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
Citation for Human Serum TIM-1/KIM-1/HAVCR Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Circulating kidney injury molecule-1 as a biomarker of renal parameters in diabetic kidney disease
Authors: T Gohda, N Kamei, T Koshida, M Kubota, K Tanaka, Y Yamashita, E Adachi, S Ichikawa, M Murakoshi, S Ueda, Y Suzuki
J Diabetes Investig, 2019;0(0):.
Sample Types: Serum
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