Human Src Alexa Fluor® 405-conjugated Antibody

Applications

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Preparation and Storage

Background: Src

The Src family of proteins are intracellular tyrosine kinases involved in cell proliferation, differentiation, motility, and survival. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Autophosphorylation in the activation loop of the kinase domain (Y419 of human Src) up‑regulates the enzyme, while phosphorylation in the C-terminal tail (Y530 of human Src) down‑regulates activity.

Product Datasheets

Related Research Areas

• Adhesion Molecules on Endothelial Cells
• Adhesion Molecules on VSMC
• Apoptosis Intracellular Kinases
• Cancer Biomarkers
• Cell to Cell Adhesion Disassembly During EMT
• Chemokine Receptor Intracellular Signaling
• C-type Lectin Receptors
• EMT Induction
• Extracellular Matrix Remodeling and Cell Migration During EMT
• Focal Adhesions
• GDNF Family
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Intracellular Signaling Molecules in Angiogenesis
• Jak and STAT Proteins
• Neurofibrillary Tangle Formation
• Platelet Signaling
• Repulsive Guidance Molecules and Receptors
• Search Kinases and Phosphatases
• Src Kinases
• TNF Superfamily Regulators
• VEGF Family