197 results for "Src" in Products
Src Products
Src and other Src family protein tyrosine kinases are proto-oncogenes that play key roles in regulating cell growth and differentiation. Src family activity is regulated by tyrosine phosphorylation at two sites with opposing effects. Phosphorylation at Y419 of human Src up-regulates kinase activity, while phosphorylation at Y530 inactivates Src.
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
| Reactivity: | Human |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #1246F |
| Applications: | WB, ICC/IF, Simple Western |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse Monoclonal Clone #5A18 |
| Applications: | IHC, WB, Simple Western |
![Western Blot: Src Antibody (5A18) [NBP1-19188]](https://resources.rndsystems.com/images/products/Src-Antibody-5A18-Western-Blot-NBP1-19188-img0004.jpg "Western Blot: Src Antibody (5A18) [NBP1-19188]")
Potent, selective Src family kinase inhibitor
| Chemical Name: | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #327537 |
| Applications: | WB |
| Reactivity: | Human |
| Assay Range: | 3.91-250 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #327554 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Source: | Sf 9 (baculovirus) |
| Accession #: | NM_005417 |
| Applications: | Bioactivity |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #7G6M9 |
| Applications: | KO, WB, ELISA, ICC/IF, IP |
| Reactivity: | Human |
| Applications: | IHC, WB, Simple Western |
Highly potent pan-Src/Bcr-Abl inhibitor
| Alternate Names: | BMS-354825 |
| Chemical Name: | N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide |
| Purity: | ≥98% |
JAK2/STAT3 signaling pathway inhibitor
| Chemical Name: | (1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester |
| Purity: | ≥98% |
Src tyrosine kinase inhibitor
| Chemical Name: | N-(2-Chloro-5-methoxyphenyl)-6-methoxy |
| Purity: | ≥98% |
Dual Src-Abl inhibitor; antiproliferative
| Alternate Names: | SKI-606 |
| Chemical Name: | 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile |
| Purity: | ≥98% |
Negative control for PP 2 (Cat. No. 1407)
| Chemical Name: | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
Dual site Src kinase inhibitor
| Chemical Name: | 6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine |
| Purity: | ≥98% |
Potent Src inhibitor; also inhibits FGFR1, PDGFRβ and Wee1
| Chemical Name: | 6-(2,6-Dichlorophenyl)-2-[[4-[2-(diethylamino)ethoxy]phenyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one dihydrochloride |
| Purity: | ≥98% |
Potent and selective Lck and Src inhibitor; also inhibits SIK
| Alternate Names: | KIN112 |
| Chemical Name: | 2,6-Dimethylphenyl-N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]carbamate |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
| Reactivity: | Viral |
| Source: | Sf 9 (baculovirus) |
| Accession #: | M11753 |
| Applications: | Bioactivity |
Potent, selective Src family kinase inhibitor
| Chemical Name: | 1-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
Src family kinase inhibitor; also inhibits c-Abl
| Alternate Names: | 1-NA-PP 1 |
| Chemical Name: | 1-(1,1-Dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Purity: | ≥98% |
Inhibitor of Src family kinases
| Chemical Name: | 7-[trans-4-(4-Methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-Pyrrolo[2,3-d]pyrimidin-4-amine trihydrochloride |
| Purity: | ≥98% |
