Human sTNF RI/TNFRSF1A Quantikine ELISA Kit

  (57 citations)     
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Product Details
Assay Procedure
Citations (57)
FAQs
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  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (200 uL), Serum (20 uL), EDTA Plasma (20 uL), Heparin Plasma (20 uL), Citrate Plasma (20 uL), Urine (20 uL)
  • Sensitivity
    1.2 pg/mL
  • Assay Range
    7.8 - 500 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma, Urine)
  • Specificity
    Natural and recombinant human sTNF RI
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    Interference observed with 1 or more available related molecules.
Control Available
QC05 , Quantikine Immunoassay Control Group 2 - Please Inquire
Product Summary
The Quantikine Human sTNF RI Immunoassay is a 4.5 hour solid phase ELISA designed to measure sTNF RI in cell culture supernates, serum, plasma, and urine. It contains E. coli-expressed recombinant human sTNF RI, as well as antibodies raised against this polypeptide. The recombinant protein represents the non-glycosylated, N-terminal methionyl form of the naturally occurring human soluble Type I receptor for TNF with an apparent molecular weight of approximately 18.6 kDa. This immunoassay has been shown to accurately quantitate the recombinant sTNF RI. Results obtained on samples containing natural sTNF RI showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values of natural sTNF RI. Since the measurement of human sTNF RI by this immunoassay is relatively insensitive to added TNF-alpha or TNF-beta, it is probable that this measurement corresponds to the total amount of the soluble receptor present in samples (i.e. the total amount of free receptor plus the total amount of receptor bound to TNF).

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Urine
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 41.5 122 231 54 251 350
Standard Deviation 2.14 5.38 11 2.7 9.7 23.3
CV% 5.2 4.4 4.8 5 3.9 6.7

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 69 198 355 54.8 252 356
Standard Deviation 3.24 7.17 17.8 4.8 9.3 20.6
CV% 4.7 3.6 5 8.8 3.7 5.8

Recovery

The recovery of sTNF RI spiked to three levels in samples throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=8) 85 80-92
EDTA Plasma (n=8) 86 70-97
Heparin Plasma (n=8) 93 79-103
Serum (n=8) 90 77-103
Urine (n=8) 85 71-109
Linearity
To assess the linearity of the assay, samples containing and/or spiked with high concentrations of sTNF RI were serially diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
 TNF RI/TNFRSF1A [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: TNF RI/TNFRSF1A
TNF RI (TNF receptor 1; TNF R-p55/p60) is a transmembrane receptor for TNF-alpha and Lymphotoxin-alpha/TNF-beta. A soluble decoy form of the receptor is shed by ADAM-17/TACE in response to inflammatory stimulation. TNF RI signaling through NFkB is essential for the development of lymph node germinal centers and Peyer’s patches and for combating intracellular pathogens such as Listeria.
  • Long Name:
    Tumor Necrosis Factor Receptor I
  • Entrez Gene IDs:
    7132 (Human); 21937 (Mouse); 25625 (Rat); 102135285 (Cynomolgus Monkey)
  • Alternate Names:
    CD120a antigen; CD120a; FPF; p55; p55-R; p60; TNF RI; TNFARMGC19588; TNF-R; TNF-R1; TNFR1TBP1; TNFR55; TNF-R55; TNFR60; TNFRI; TNF-RI; TNF-R-I; TNFR-I; TNFRSF1A; tumor necrosis factor binding protein 1; Tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; Tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor
Related Research Areas
Assay Procedure
Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 50 µL Assay Diluent
  4.   Add 50 µL of Assay Diluent to each well.

  5. 200 µL Standard, Control, or Sample
  6.   Add 200 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process twice for a total of 3 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 3 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well. Incubate at room temperature for 20 minutes. PROTECT FROM LIGHT.

  13. 50 µL Stop Solution
  14. Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

57 Citations: Showing 1 - 10
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Species
Sample Type
  1. Effects of an Encapsulated Fruit and Vegetable Juice Concentrate on Obesity-Induced Systemic Inflammation: A Randomised Controlled Trial
    Authors: EJ Williams, KJ Baines, BS Berthon, LG Wood
    Nutrients, 2017;9(2):.
    Species: Human
    Sample Type: Plasma
  2. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
    Authors: AT Holdbrooks, CM Britain, SL Bellis
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  3. Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV
    Authors: MA Belury, E Bowman, J Gabriel, B Snyder, M Kulkarni, M Palettas, X Mo, JE Lake, D Zidar, SF Sieg, B Rodriguez, MP Playford, A Andrade, DR Kuritzkes, NN Mehta, MM Lederman, NT Funderburg
    Pathog Immun, 2017;2(3):376-403.
    Species: Human
    Sample Type: Plasma
  4. Reevaluation of immune activation in the era of cART and an aging HIV-infected population
    Authors: LR de Armas, S Pallikkuth, V George, S Rinaldi, R Pahwa, KL Arheart, S Pahwa
    JCI Insight, 2017;2(20):.
    Species: Human
    Sample Type: Plasma
  5. Distinctive inflammatory profile between acute focal bacterial nephritis and acute pyelonephritis in children
    Authors: M Mizutani, S Hasegawa, T Matsushige, N Ohta, S Kittaka, M Hoshide, T Kusuda, K Takahashi, K Ichihara, S Ohga
    Cytokine, 2017;99(0):24-29.
    Species: Human
    Sample Type: Serum
  6. Activation of muscarinic receptors prevents TNF-?-mediated intestinal epithelial barrier disruption through p38 MAPK
    Authors: J Uwada, T Yazawa, MT Islam, MRI Khan, SM Krug, M Fromm, SI Karaki, Y Suzuki, A Kuwahara, H Yoshiki, K Sada, Muramatsu, T Taniguchi
    Cell. Signal., 2017;0(0):.
    Species: Human
    Sample Type: Cell Culture Supernates
  7. Circulating TNF Receptors 1 and 2 Predict Mortality in Patients with End-stage Renal Disease Undergoing Dialysis
    Authors: T Gohda, S Maruyama, N Kamei, S Yamaguchi, T Shibata, M Murakoshi, S Horikoshi, Y Tomino, I Ohsawa, H Gotoh, S Nojiri, Y Suzuki
    Sci Rep, 2017;7(0):43520.
    Species: Human
    Sample Type: Serum
  8. Soluble Tumor Necrosis Factor Receptors and Arterial Stiffness in Patients With Coronary Atherosclerosis
    Authors: Hack-Lyoung Kim
    Am. J. Hypertens, 2016;0(0):.
    Species: Human
    Sample Type: Plasma
  9. Prevalent peripheral arterial disease and inflammatory burden
    BMC Geriatr, 2016;16(1):213.
    Species: Human
    Sample Type: Serum
  10. Association between serum soluble tumor necrosis factor-? receptors and early childhood obesity
    Authors: S Ouyang, W Li, Z Liu, Y Li, S Li, J Wu
    Endocr J, 2016;0(0):.
    Species: Human
    Sample Type: Serum
  11. Anti-Drug Antibodies, Drug Levels, Interleukin-6 and Soluble TNF Receptors in Rheumatoid Arthritis Patients during the First 6 Months of Treatment with Adalimumab or Infliximab: A Descriptive Cohort Study
    PLoS ONE, 2016;11(9):e0162316.
    Species: Human
    Sample Type: Serum
  12. Anti-TNF-? Drugs Differently Affect the TNF?-sTNFR System and Monocyte Subsets in Patients with Psoriasis
    PLoS ONE, 2016;11(12):e0167757.
    Species: Human
    Sample Type: Plasma
  13. Altered Monocyte and Endothelial Cell Adhesion Molecule Expression Is Linked to Vascular Inflammation in Human Immunodeficiency Virus Infection
    Authors: M Kulkarni, E Bowman, J Gabriel, T Amburgy, E Mayne, DA Zidar, C Maierhofer, AN Turner, JA Bazan, SL Koletar, MM Lederman, SF Sieg, NT Funderburg
    Open Forum Infect Dis, 2016;3(4):ofw224.
    Species: Human
    Sample Type: Plasma
  14. Inflammatory Markers and the Risk of Hip and Vertebral Fractures in Men: the Osteoporotic Fractures in Men (MrOS)
    J Bone Miner Res, 2016;0(0):.
    Species: Human
    Sample Type: Serum
  15. Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Type: Serum
  16. Plasma TNF-alpha and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study.
    Authors: Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, Miriyala S, Keeney J, Ren X, Sultana R, Vore M, Butterfield D, St Clair D, Moscow J
    PLoS ONE, 2015;10(4):e0124988.
    Species: Human
    Sample Type: Plasma
  17. Circulating TNF receptors 1 and 2 are associated with the severity of renal interstitial fibrosis in IgA nephropathy.
    Authors: Sonoda Y, Gohda T, Suzuki Y, Omote K, Ishizaka M, Matsuoka J, Tomino Y
    PLoS ONE, 2015;10(4):e0122212.
    Species: Human
    Sample Type: Serum
  18. T. vaginalis Infection Is Associated with Increased IL-8 and TNFr1 Levels but with the Absence of CD38 and HLADR Activation in the Cervix of ESN.
    Authors: Jarrett O, Brady K, Modur S, Plants J, Landay A, Ghassemi M, Golub E, Spear G, Novak R
    PLoS ONE, 2015;10(6):e0130146.
    Species: Human
    Sample Type: Cervical Fluid
  19. Late Antiretroviral Therapy (ART) Initiation Is Associated with Long-Term Persistence of Systemic Inflammation and Metabolic Abnormalities.
    Authors: Ghislain M, Bastard J, Meyer L, Capeau J, Fellahi S, Gerard L, May T, Simon A, Vigouroux C, Goujard C
    PLoS ONE, 2015;10(12):e0144317.
    Species: Human
    Sample Type: Serum
  20. Circulating levels of tumor necrosis factor-alpha receptor 2 are increased in heart failure with preserved ejection fraction relative to heart failure with reduced ejection fraction: evidence for a divergence in pathophysiology.
    Authors: Putko B, Wang Z, Lo J, Anderson T, Becher H, Dyck J, Kassiri Z, Oudit G
    PLoS ONE, 2014;9(6):e99495.
    Species: Human
    Sample Type: Plasma
  21. The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study.
    Authors: Pisetsky D, Trace S, Brownley K, Hamer R, Zucker N, Roux-Lombard P, Dayer J, Bulik C
    Cytokine, 2014;69(1):110-5.
    Species: Human
    Sample Type: Cell Culture Supernates
  22. A case-control study of pre-operative levels of serum neutrophil gelatinase-associated lipocalin and other potential inflammatory markers in colorectal cancer.
    Authors: Duvillard L, Ortega-Deballon P, Bourredjem A, Scherrer M, Mantion G, Delhorme J, Deguelte-Lardiere S, Petit J, Bonithon-Kopp C
    BMC Cancer, 2014;14(0):912.
    Species: Human
    Sample Type: Serum
  23. Dynamics of immune reconstitution and activation markers in HIV+ treatment-naive patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine.
    Authors: Funderburg N, Andrade A, Chan E, Rosenkranz S, Lu D, Clagett B, Pilch-Cooper H, Rodriguez B, Feinberg J, Daar E, Mellors J, Kuritzkes D, Jacobson J, Lederman M
    PLoS ONE, 2013;8(12):e83514.
    Species: Human
    Sample Type: Plasma
  24. IL-18-based combinatorial adjuvants promote the intranodal production of CCL19 by NK cells and dendritic cells of cancer patients.
    Authors: Wong J, Muthuswamy R, Bartlett D, Kalinski P
    Oncoimmunology, 2013;2(9):e26245.
    Species: Human
    Sample Type: Whole Cells
  25. Risk of ESRD and all cause mortality in type 2 diabetes according to circulating levels of FGF-23 and TNFR1.
    Authors: Lee J, Gohda T, Walker W, Skupien J, Smiles A, Holak R, Jeong J, McDonnell K, Krolewski A, Niewczas M
    PLoS ONE, 2013;8(3):e58007.
    Species: Human
    Sample Type: Plasma
  26. Compensated inflammation in systemic juvenile idiopathic arthritis: role of alternatively activated macrophages.
    Authors: Shimizu M, Yachie A
    Cytokine, 2012;60(1):226-32.
    Species: Human
    Sample Type: Serum
  27. Inflammatory markers and the risk of hip fracture: the Women's Health Initiative.
    Authors: Barbour KE, Boudreau R, Danielson ME, Youk AO, Wactawski-Wende J, Greep NC, LaCroix AZ, Jackson RD, Wallace RB, Bauer DC, Allison MA, Cauley JA
    J. Bone Miner. Res., 2012;27(5):1167-76.
    Species: Human
    Sample Type: Serum
  28. Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort.
    Authors: Grote VA, Kaaks R, Nieters A, Tjonneland A, Halkjaer J, Overvad K, Skjelbo Nielsen MR, Boutron-Ruault MC, Clavel-Chapelon F, Racine A, Teucher B, Becker S, Pischon T, Boeing H, Trichopoulou A, Cassapa C, Stratigakou V, Palli D, Krogh V, Tumino R, Vineis P, Panico S, Rodriguez L, Duell EJ, Sanchez MJ, Dorronsoro M, Navarro C, Gurrea AB, Siersema PD, Peeters PH, Ye W, Sund M, Lindkvist B, Johansen D, Khaw KT, Wareham N, Allen NE, Travis RC, Fedirko V, Jenab M, Michaud DS, Chuang SC, Romaguera D, Bueno-de-Mesquita HB, Rohrmann S
    Br. J. Cancer, 2012;106(11):1866-74.
    Species: Human
    Sample Type: Serum
  29. Elevated CSF levels of TACE activity and soluble TNF receptors in subjects with mild cognitive impairment and patients with Alzheimer's disease.
    Authors: Jiang H, Hampel H, Prvulovic D, Wallin A, Blennow K, Li R, Shen Y
    Mol Neurodegener, 2011;6(0):69.
    Species: Human
    Sample Type: CSF
  30. Cytokine Response Patterns in Severe Pandemic 2009 H1N1 and Seasonal Influenza among Hospitalized Adults.
    Authors: Lee N, Wong CK, Chan PK, Chan MC, Wong RY, Lun SW, Ngai KL, Lui GC, Wong BC, Lee SK, Choi KW, Hui DS
    PLoS ONE, 2011;6(10):e26050.
    Species: Human
    Sample Type: Plasma
  31. Matrix metalloproteinase-9 and plasminogen activator inhibitor-1 are associated with right ventricular structure and function: the MESA-RV Study.
    Authors: Kawut SM, Barr RG, Johnson WC
    Biomarkers, 2010;15(8):731-8.
    Species: Human
    Sample Type: Plasma
  32. Adrenomedullin and endothelin-1 are related to inflammation in chronic heart failure.
    Authors: Gombos T, Forhecz Z, Pozsonyi Z, Wallentin S, Papassotiriou J, Kunde J, Morgenthaler NG, Janoskuti L, Prohaszka Z
    Inflamm. Res., 2009;58(6):298-305.
    Species: Human
    Sample Type: Serum
  33. Change in plasma tumor necrosis factor receptor 1 levels in the first week after myeloablative allogeneic transplantation correlates with severity and incidence of GVHD and survival.
    Authors: Choi SW, Kitko CL, Braun T, Paczesny S, Yanik G, Mineishi S, Krijanovski O, Jones D, Whitfield J, Cooke K, Hutchinson RJ, Ferrara JL, Levine JE
    Blood, 2008;112(4):1539-42.
    Species: Human
    Sample Type: Plasma
  34. Selective effects of CPAP on sleep apnoea-associated manifestations.
    Authors: Vgontzas AN, Zoumakis E, Bixler EO, Lin HM, Collins B, Basta M, Pejovic S, Chrousos GP
    Eur. J. Clin. Invest., 2008;38(8):585-95.
    Species: Human
    Sample Type: Plasma
  35. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure.
    Authors: Denollet J, Vrints CJ, Conraads VM
    Brain Behav. Immun., 2008;22(5):736-43.
    Species: Human
    Sample Type: Plasma
  36. Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease.
    Authors: Doucet M, Russell AP, Leger B, Debigare R, Joanisse DR, Caron MA, LeBlanc P, Maltais F
    Am. J. Respir. Crit. Care Med., 2007;176(3):261-9.
    Species: Human
    Sample Type: Plasma
  37. Serum interleukin-18 and soluble tumour necrosis factor receptor 2 are associated with disease severity in patients with paracoccidioidomycosis.
    Authors: Corvino CL, Mamoni RL, Fagundes GZ, Blotta MH
    Clin. Exp. Immunol., 2007;147(3):483-90.
    Species: Human
    Sample Type: Serum
  38. Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study.
    Authors: Cauley JA, Danielson ME, Boudreau RM, Forrest KY, Zmuda JM, Pahor M, Tylavsky FA, Cummings SR, Harris TB, Newman AB
    J. Bone Miner. Res., 2007;22(7):1088-95.
    Species: Human
    Sample Type: Serum
  39. Microparticles of human atherosclerotic plaques enhance the shedding of the tumor necrosis factor-alpha converting enzyme/ADAM17 substrates, tumor necrosis factor and tumor necrosis factor receptor-1.
    Authors: Canault M, Leroyer AS, Peiretti F, Leseche G, Tedgui A, Bonardo B, Alessi MC, Boulanger CM, Nalbone G
    Am. J. Pathol., 2007;171(5):1713-23.
    Species: Human
    Sample Type: Cell Culture Supernates
  40. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.
    Authors: Kissel CK, Lehmann R, Assmus B, Aicher A, Honold J, Fischer-Rasokat U, Heeschen C, Spyridopoulos I, Dimmeler S, Zeiher AM
    J. Am. Coll. Cardiol., 2007;49(24):2341-9.
    Species: Human
    Sample Type: Serum
  41. Neutrophils from patients with TNFRSF1A mutations display resistance to tumor necrosis factor-induced apoptosis: pathogenetic and clinical implications.
    Authors: D&amp;amp;apos;Osualdo A
    Arthritis Rheum., 2006;54(3):998-1008.
    Species: Human
    Sample Type: Cell Culture Supernates
  42. Proinflammatory cytokines, insulin resistance, and insulin secretion in chronic hepatitis C patients: A case-control study.
    Authors: Lecube A, Hernandez C, Genesca J, Simo R
    Diabetes Care, 2006;29(5):1096-101.
    Species: Human
    Sample Type: Serum
  43. The shedding activity of ADAM17 is sequestered in lipid rafts.
    Authors: Tellier E, Rebsomen L
    Exp. Cell Res., 2006;312(20):3969-80.
    Species: Primate - Cholrocebus pygerythrus (Vervet Monkey)
    Sample Type: Cell Lysates
  44. Levels of soluble cytokine factors in temporomandibular joint effusions seen on magnetic resonance images.
    Authors: Kaneyama K, Segami N, Sun W, Sato J, Fujimura K
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005;99(4):411-8.
    Species: Human
    Sample Type: Synovial Fluid
  45. Analysis of tumor necrosis factor-alpha, interleukin-6, interleukin-1beta, soluble tumor necrosis factor receptors I and II, interleukin-6 soluble receptor, interleukin-1 soluble receptor type II, interleukin-1 receptor antagonist, and protein in the synovial fluid of patients with temporomandibular joint disorders.
    Authors: Kaneyama K, Segami N, Sun W, Sato J, Fujimura K
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2005;99(3):276-84.
    Species: Human
    Sample Type: Synovial Fluid
  46. Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage.
    Authors: Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S
    Crit. Care Med., 2005;33(6):1359-64.
    Species: Human
    Sample Type: Cell Culture Supernates
  47. Experimental heatstroke in baboon: analysis of the systemic inflammatory response.
    Authors: Bouchama A, Ollivier V, Roberts G, Al Mohanna F, de Prost D, Eldali A, Saussereau E, El-Sayed R, Chollet-Martin S
    Shock, 2005;24(4):332-5.
    Species: Primate - Papio hamadryas (Hamadyras Baboon)
    Sample Type: Plasma
  48. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Authors: Vergne-Salle&lt;/LastName&gt;&lt;F P&lt;/Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
    Cytokine, 2005;31(5):335-48.
    Species: Human
    Sample Type: Cell Culture Supernates
  49. Growth hormone-induced reduction of soluble apoptosis mediators is associated with reverse cardiac remodelling and improvement of exercise capacity in patients with idiopathic dilated cardiomyopathy.
    Authors: Parissis JT, Adamopoulos S, Karatzas D, Paraskevaidis J, Livanis E, Kremastinos D
    Eur J Cardiovasc Prev Rehabil, 2005;12(2):164-8.
    Species: Human
    Sample Type: Plasma
  50. Pro- and anti-inflammatory responses in respiratory syncytial virus bronchiolitis.
    Authors: McNamara PS, Flanagan BF, Selby AM, Hart CA, Smyth RL
    Eur. Respir. J., 2004;23(1):106-12.
    Species: Human
    Sample Type: BALF
  51. Release of full-length 55-kDa TNF receptor 1 in exosome-like vesicles: a mechanism for generation of soluble cytokine receptors.
    Authors: Hawari FI, Rouhani FN, Cui X, Yu ZX, Buckley C, Kaler M, Levine SJ
    Proc. Natl. Acad. Sci. U.S.A., 2004;101(5):1297-302.
    Species: Human
    Sample Type: Cell Culture Supernates
  52. Gene transfer of tumor necrosis factor inhibitor improves the function of lung allografts.
    Authors: Tagawa T, Kozower BD, Kanaan SA, Daddi N, Muraoka M, Oka T, Ritter JH, Patterson GA
    J. Thorac. Cardiovasc. Surg., 2004;127(6):1558-63.
    Species: Human
    Sample Type: Tissue Homogenates
  53. Arenavirus-mediated liver pathology: acute lymphocytic choriomeningitis virus infection of rhesus macaques is characterized by high-level interleukin-6 expression and hepatocyte proliferation.
    Authors: Lukashevich IS, Tikhonov I, Rodas JD, Zapata JC, Yang Y, Djavani M, Salvato MS
    J. Virol., 2003;77(3):1727-37.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Serum
  54. Age-related autoantibody production in a nonhuman primate model.
    Authors: Attanasio R, Brasky KM, Robbins SH, Jayashankar L, Nash RJ, Butler TM
    Clin. Exp. Immunol., 2001;123(3):361-5.
    Species: Primate - Papio cynocephalus (Yellow Baboon)
    Sample Type: Serum
  55. Proinflammatory cytokines increase in sepsis after anti-adhesion molecule therapy.
    Authors: Welty-Wolf KE, 2016, Carraway MS, Ghio A, Kantrow SP, Huang YC, Piantadosi CA
    1-23, 2000;13(5):404-9.
    Species: Primate - Papio cynocephalus (Yellow Baboon)
    Sample Type: Serum
  56. An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline.
    Authors: Otterness IG, Swindell AC, Zimmerer RO, Poole AR, Ionescu M, Weiner E
    Osteoarthr. Cartil., 2000;8(3):180-5.
    Species: Human
    Sample Type: Serum
  57. Tumour necrosis factor alpha and its soluble receptors in juvenile chronic arthritis.
    Authors: Rooney M, Varsani H, Martin K, Lombard PR, Dayer JM, Woo P
    Rheumatology (Oxford), 2000;39(4):432-8.
    Species: Human
    Sample Type: Serum
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