Human TGF-beta RII PE-conjugated Antibody Summary
Accession # P37173.2
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of TGF-beta RII in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Goat Anti-Human TGF-beta RII PE-conjugated Antigen Affinity-purified Polyclonal Antibody (Catalog # FAB2411P, filled histogram) or isotype control antibody (Catalog # IC108P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Background: TGF-beta RII
TGF beta RII is a membrane bound serine/threonine kinase. Upon ligand binding, TGF beta RII interacts with TGF beta RI to form the heteromeric signaling complex thattransduces TGF beta signals. A splice variant of the type II receptor, TGF beta RIIb, containing a 25 amino acid residue insertion near the Nterminus of the mature protein has also been described.
Citation for Human TGF-beta RII PE-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
TGF-beta limits IL-33 production and promotes the resolution of colitis through regulation of macrophage function.
Authors: Rani R, Smulian AG, Greaves DR, Hogan SP, Herbert DR
Eur. J. Immunol., 2011;41(7):2000-9.
Sample Types: Whole Cells
Applications: Flow Cytometry
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