Human Total Adiponectin/Acrp30 Quantikine ELISA Kit

  (86 citations)
(4 Reviews)
    
Datasheet / CoA / SDS
Product Details
Assay Procedure
Citations (86)
FAQs
Supplemental Products
Reviews
  • Assay Type
    Solid Phase Sandwich ELISA
  • Format
    96-well strip plate
  • Assay Length
    4.5 hours
  • Sample Type & Volume Required Per Well
    Cell Culture Supernates (50 uL), Serum (10 uL), EDTA Plasma (10 uL), Heparin Plasma (10 uL)
  • Sensitivity
    0.891 ng/mL
  • Assay Range
    3.9 - 250 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma)
  • Specificity
    Natural and recombinant human total Adiponectin (low, middle, and high molecular weight)
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC237 , Quantikine Immunoassay Control Group 237 - Please Inquire
Product Summary
The Quantikine Human Total Adiponectin Immunoassay is a 4.5 hour solid-phase ELISA designed to measure total (low, middle, and high molecular weight) human Adiponectin in cell culture supernates, serum, and plasma. It contains NS0-expressed recombinant human Adiponectin and has been shown to accurately quantitate the recombinant factor. Results obtained using natural human Adiponectin showed linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring Adiponectin.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean 12.5 45.3 91.5 12.7 47.1 100
Standard Deviation 0.41 1.27 4.56 1 2.8 6.7
CV% 3.2 2.8 5 7.9 5.9 6.7

Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 40 40 40
Mean 19.8 69.9 143 20.5 74.4 157
Standard Deviation 0.5 2.4 6.76 1.4 4.3 10.8
CV% 2.5 3.4 4.7 6.8 5.8 6.9

Recovery

The recovery of Adiponectin spiked to levels throughout the range of the assay was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Media (n=4) 101 88-112
Linearity
To assess the linearity of the assay, samples containing and/or spiked with high concentrations of Adiponectin were serially diluted with the appropriate Calibrator Diluent to produce samples with values within the dynamic range of the assay.
 Adiponectin/Acrp30 [HRP]
Product Datasheets

Certificate of Analysis Lookup

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Note: Certificate of Analysis not available for kit components.

Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: Adiponectin/Acrp30

Adiponectin (also known as Adipocyte complement-related protein of 30 kDa, Acrp30) is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. Adiponectin associates into 70 kDa noncovalently-linked trimers that are disulfide-linked into medium molecular weight hexamers and then into >300 kDa high molecular weight oligomers.

  • Entrez Gene IDs:
    9370 (Human); 11450 (Mouse); 246253 (Rat)
  • Alternate Names:
    ACDC; Acrp30; ACRP30ADPN; adipocyte, C1Q and collagen domain containing; Adiponectin; adiponectin, C1Q and collagen domain containing; AdipoQ; ADIPQTL1; ApM1; apM-1; APM1APM-1; C1q and collagen domain-containing protein; GBP28; GBP28apM1; Gelatin-binding protein
Related Research Areas
Assay Procedure
Refer to the product for complete assay procedure.

Bring all reagents and samples to room temperature before use. It is recommended that all samples, standards, and controls be assayed in duplicate.
  1.   Prepare all reagents, standard dilutions, and samples as directed in the product insert.
  2.   Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.

  3. 100 µL Assay Diluent
  4.   Add 100 µL of Assay Diluent to each well.

  5. 50 µL Standard, Control, or Sample
  6.   Add 50 µL of Standard, control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
  7.   Aspirate each well and wash, repeating the process 3 times for a total of 4 washes.

  8. 200 µL Conjugate
  9.   Add 200 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
  10.   Aspirate and wash 4 times.

  11. 200 µL Substrate Solution
  12.   Add 200 µL Substrate Solution to each well.
  13.   For Cell Culture Supernate Samples: Incubate at room temperature for 20 minutes. PROTECT FROM LIGHT.
    For Serum & Plasma Samples: Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.

  14. 50 µL Stop Solution
  15. Add 50 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

86 Citations: Showing 1 - 10
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Species
Sample Type
  1. Association between interleukin-6, C-reactive protein and adiponectin with adiposity: Findings from the 1993 pelotas (Brazil) birth cohort at 18 and 22?years
    Authors: AMB Menezes, PD Oliveira, FC Wehrmeiste, H Gonçalves, MCF Assunção, L Tovo-Rodri, GD Ferreira, IO Oliveira
    Cytokine, 2018;110(0):44-51.
    Species: Human
    Sample Type: Serum
  2. Plasma leptin, but not resistin, TNF-? and adiponectin, is associated with echocardiographic parameters of cardiac remodeling in patients with coronary artery disease
    Authors: AD Farca?, A Rusu, MA Stoia, LA Vida-Simit
    Cytokine, 2018;103(0):46-49.
    Species: Human
    Sample Type: Plasma
  3. The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes
    Authors: TJ Orchard, B Cariou, MA Connelly, JD Otvos, S Zhang, CJ Antalis, T Ivanyi, BJ Hoogwerf
    Cardiovasc Diabetol, 2017;16(1):73.
    Species: Human
    Sample Type: Serum
  4. Serum levels of leptin and adiponectin and clinical parameters in women with fibromyalgia and overweight/obesity
    Authors: ES Paiva, A Andretta, ED Batista, MM Lobo, RC Miranda, R Nisihara, ME Schieferde, CL Boguszewsk
    Arch Endocrinol Metab, 2017;0(0):0.
    Species: Human
    Sample Type: Serum
  5. Metabolic milieu associates with impaired skeletal characteristics in obesity
    Authors: HT Viljakaine, HA Koistinen, T Tervaharti, T Sorsa, S Andersson, O Mäkitie
    PLoS ONE, 2017;12(6):e0179660.
    Species: Human
    Sample Type: Serum
  6. Adipokines, C-reactive protein and Amyotrophic Lateral Sclerosis - results from a population- based ALS registry in Germany
    Authors: G Nagel, RS Peter, A Rosenbohm, W Koenig, L Dupuis, D Rothenbach, AC Ludolph
    Sci Rep, 2017;7(1):4374.
    Species: Human
    Sample Type: Serum
  7. Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
    Authors: M Solis-Pare, G Estrada-Gu, O Perichart-, A Montoya-Es, M Guzmán-Hue, H Borboa-Oli, E Bravo-Flor, A Cardona-Pé, V Zaga-Clave, E Garcia-Lat, G Gonzalez-P, JA Hernández-, C Irles
    Int J Mol Sci, 2017;19(1):.
    Species: Human
    Sample Type: Serum
  8. Myostatin and adipokines: The role of the metabolically unhealthy obese phenotype in muscle function and aerobic capacity in young adults
    Authors: LP Carvalho, RP Basso-Vane, L Di Thommaz, RG Mendes, MC Oliveira-J, RP Vieira, JC Bonjorno-J, CR Oliveira, R Luporini, A Borghi-Sil
    Cytokine, 2017;0(0):.
    Species: Human
    Sample Type: Plasma
  9. Ghrelin and hormonal markers under exercise training in patients with heart failure with preserved ejection fraction: results from the Ex-DHF pilot study
    Authors: TD Trippel, V Holzendorf, M Halle, G Gelbrich, K Nolte, A Duvinage, S Schwarz, T Rutscher, J Wiora, R Wachter, C Herrmann-L, HD Duengen, G Hasenfu beta, B Pieske, F Edelmann
    ESC Heart Fail, 2017;4(1):56-65.
    Species: Human
    Sample Type: Serum
  10. The effect of BMI, serum leptin, and adiponectin levels on prognosis in patients with non-ischaemic dilated cardiomyopathy
    Authors: C Wojciechow, W Jache?, E Romuk, E Nowalany-K, A Tomasik, L Siemi?ska
    Endokrynol Pol, 2017;68(1):26-34.
    Species: Human
    Sample Type: Serum
  11. Regional Differences Between Perisynovial and Infrapatellar Adipose Tissue Depots and Their Response to Class II and III Obesity in Patients with OA
    Authors: NS Harasymowi, ND Clement, A Azfer, R Burnett, DM Salter, AH Simpson
    Arthritis & rheumatology (Hoboken, N.J.), 2017;0(0):.
    Species: Human
    Sample Type: Tissue Homogenates
  12. Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma during the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severity
    Authors: K Tang, C Zhang, Y Zhang, Y Zhang, R Zhuang, B Jin, Y Ma
    J Immunol Res, 2017;2017(0):6468097.
    Species: Human
    Sample Type: Plasma
  13. Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial
    Authors: TH Kim, JS Chang, KS Park, J Park, N Kim, JI Lee, ID Kong
    PLoS ONE, 2017;12(2):e0171771.
    Species: Human
    Sample Type: Serum
  14. The impact of obesity and adiponectin signaling in patients with renal cell carcinoma: A potential mechanism for the obesity paradox
    Authors: R Ito, S Narita, M Huang, T Nara, K Numakura, K Takayama, H Tsuruta, A Maeno, M Saito, T Inoue, N Tsuchiya, S Satoh, T Habuchi
    PLoS ONE, 2017;12(2):e0171615.
    Species: Human
    Sample Type: Serum
  15. The short-term and long-term effects of bariatric/metabolic surgery on subcutaneous adipose tissue inflammation in humans
    Authors: DK Hagman, I Larson, JN Kuzma, G Cromer, K Makar, KB Rubinow, KE Foster-Sch, B van Yserlo, PS Billing, RW Landerholm, M Crouthamel, DR Flum, DE Cummings, M Kratz
    Metab. Clin. Exp., 2017;70(0):12-22.
    Species: Human
    Sample Type: Plasma
  16. Concurrent Aerobic and Resistance Training Has Anti-Inflammatory Effects and Increases Both Plasma and Leukocyte Levels of IGF-1 in Late Middle-Aged Type 2 Diabetic Patients
    Authors: G Annibalini, F Lucertini, D Agostini, L Vallorani, A Gioacchini, E Barbieri, M Guescini, L Casadei, A Passalia, M Del Sal, G Piccoli, M Andreani, A Federici, V Stocchi
    Oxid Med Cell Longev, 2017;2017(0):3937842.
    Species: Human
    Sample Type: Plasma
  17. Metabolic Syndrome and Selective Inflammatory Markers in Psoriatic Patients
    Authors: S Vachatova, C Andrys, J Krejsek, M Salavec, K Ettler, V Rehacek, E Cermakova, A Malkova, Z Fiala, L Borska
    J Immunol Res, 2016;2016(0):5380792.
    Species: Human
    Sample Type: Serum
  18. Insulin Resistance in Adipose Tissue but Not in Liver Is Associated with Aortic Valve Calcification
    Authors: E Jorge-Gala, C Posadas-Ro, M Torres-Tam, AX Medina-Urr, MA Rodas-D¡az, R Posadas-S , G Vargas-Ala, MD Gonz lez-S, GC Cardoso-Sa, JG Ju rez-Roj
    Dis. Markers, 2016;2016(0):9085474.
    Species: Human
    Sample Type: Serum
  19. Subclinical Inflammation and Endothelial Dysfunction in Young Patients with Diabetes: A Study from United Arab Emirates
    PLoS ONE, 2016;11(7):e0159808.
    Species: Human
    Sample Type: Serum
  20. A rapid and precise method for measuring plasma apoE-rich HDL using polyethylene glycol and cation-exchange chromatography: a pilot study on the clinical significance of apoE-rich HDL measurements
    Authors: Toru Ikeda
    Clin. Chim. Acta, 2016;465(0):112-118.
    Species: Human
    Sample Type: Plasma
  21. Altered Systemic Adipokines in Patients with Chronic Urticaria
    Authors: Hoang Kim Tu Trinh
    Int. Arch. Allergy Immunol, 2016;171(2):102-110.
    Species: Human
    Sample Type: Serum
  22. Effects of different degrees of insulin resistance on endothelial function in�obese�adults undergoing alternate day�fasting
    Authors: Kristin K Hoddy
    Nutr Healthy Aging, 2016;4(1):63-71.
    Species: Human
    Sample Type: Plasma
  23. Receptor-interacting protein 2 (RIP2) gene polymorphisms are associated with increased risk of subclinical atherosclerosis and clinical and metabolic parameters. The Genetics of Atherosclerotic Disease (GEA) Mexican study
    Authors: Rosalinda Posadas-Sá
    Exp. Mol. Pathol, 2016;102(1):1-6.
    Species: Human
    Sample Type: Serum
  24. Dietary patterns and cardiometabolic and endocrine plasma biomarkers in US women
    Authors: Hala B AlEssa
    Am. J. Clin. Nutr, 2016;0(0):.
    Species: Human
    Sample Type: Plasma
  25. Rice Bran Extract Reduces the Risk of Atherosclerosis in Post-Menopausal Vietnamese Women
    Authors: Bui Thi Nhung
    J. Nutr. Sci. Vitaminol, 2016;62(5):295-302.
    Species: Human
    Sample Type: Serum
  26. comparative study of glucose homeostasis, lipids and lipoproteins, HDL functionality, and cardiometabolic parameters in modestly severely obese African Americans and White Americans with prediabetes: implications for the metabolic paradoxes.
    Authors: Healy S, Osei K, Gaillard T
    Diabetes Care, 2015;38(2):228-35.
    Species: Human
    Sample Type: Serum
  27. Additive regulation of adiponectin expression by the mediterranean diet olive oil components oleic Acid and hydroxytyrosol in human adipocytes.
    Authors: Scoditti E, Massaro M, Carluccio M, Pellegrino M, Wabitsch M, Calabriso N, Storelli C, De Caterina R
    PLoS ONE, 2015;10(6):e0128218.
    Species: Human
    Sample Type: Cell Culture Supernates
  28. Ectopic fat storage in the pancreas using 1H-MRS: importance of diabetic status and modulation with bariatric surgery-induced weight loss.
    Authors: Gaborit B, Abdesselam I, Kober F, Jacquier A, Ronsin O, Emungania O, Lesavre N, Alessi M, Martin J, Bernard M, Dutour A
    Int J Obes (Lond), 2015;39(3):480-7.
    Species: Human
    Sample Type: Plasma
  29. Longitudinal Analysis of Adiponectin through 20-Year Type 1 Diabetes Duration.
    Authors: LeCaire T, Palta M
    J Diabetes Res, 2015;2015(0):730407.
    Species: Human
    Sample Type: Plasma
  30. The effect of a Diabetes-Specific Cognitive Behavioral Treatment Program (DIAMOS) for patients with diabetes and subclinical depression: results of a randomized controlled trial.
    Authors: Hermanns N, Schmitt A, Gahr A, Herder C, Nowotny B, Roden M, Ohmann C, Kruse J, Haak T, Kulzer B
    Diabetes Care, 2015;38(4):551-60.
    Species: Human
    Sample Type: Serum
  31. Role of adiponectin and free fatty acids on the association between abdominal visceral fat and insulin resistance.
    Authors: Medina-Urrutia A, Posadas-Romero C, Posadas-Sanchez R, Jorge-Galarza E, Villarreal-Molina T, Gonzalez-Salazar M, Cardoso-Saldana G, Vargas-Alarcon G, Torres-Tamayo M, Juarez-Rojas J
    Cardiovasc Diabetol, 2015;14(0):20.
    Species: Human
    Sample Type: Serum
  32. Adverse Fat Depots and Marrow Adiposity Are Associated With Skeletal Deficits and Insulin Resistance in Long-Term Survivors of Pediatric Hematopoietic Stem Cell Transplantation.
    Authors: Mostoufi-Moab S, Magland J, Isaacoff E, Sun W, Rajapakse C, Zemel B, Wehrli F, Shekdar K, Baker J, Long J, Leonard M
    J Bone Miner Res, 2015;30(9):1657-66.
    Species: Human
    Sample Type: Serum
  33. Circulating adipokines and insulin resistance in subjects with combined cardiac and metabolic syndrome X.
    Authors: Liang K, Lee W, Lee W, Liao Y, Wang K, Lee I, Wang J, Sheu W
    Diabetol Metab Syndr, 2015;7(0):83.
    Species: Human
    Sample Type: Serum
  34. Adiponectin and bariatric surgery: associations with diabetes and cardiovascular disease in the Swedish Obese Subjects Study.
    Authors: Herder C, Peltonen M, Svensson P, Carstensen M, Jacobson P, Roden M, Sjostrom L, Carlsson L
    Diabetes Care, 2014;37(5):1401-9.
    Species: Human
    Sample Type: Serum
  35. Effect of Sfrp5 on cytokine release and insulin action in primary human adipocytes and skeletal muscle cells.
    Authors: Carstensen M, Wiza C, Rohrig K, Fahlbusch P, Roden M, Herder C, Ouwens D
    PLoS ONE, 2014;9(1):e85906.
    Species: Human
    Sample Type: Cell Culture Supernates
  36. Association of serum vaspin and adiponectin levels with renal function in patients with or without type 2 diabetes mellitus.
    Authors: Yan, Meiyu, Su, Bin, Peng, Wenhui, Li, Liang, Li, Hailing, Zhuang, Jianhui, Lu, Yuyan, Jian, Weixia, Wei, Yidong, Li, Weiming, Qu, Shen, Xu, Yawei
    J Diabetes Res, 2014;2014(0):868732.
    Species: Human
    Sample Type: Plasma
  37. Phase I study of Efatutazone, an oral PPARgamma agonist, in patients with metastatic solid tumors.
    Authors: Murakami H, Ono A, Takahashi T, Onozawa Y, Tsushima T, Yamazaki K, Jikoh T, Boku N, Yamamoto N
    Anticancer Res, 2014;34(9):5133-41.
    Species: Human
    Sample Type: Plasma
  38. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013;8(12):e83042.
    Species: Human
    Sample Type: Plasma
  39. Obesity and IL-6 interact in modulating the response to endotoxemia in mice.
    Cytokine, 2013;61(1):71-7.
    Species: Mouse
    Sample Type: Plasma
  40. Exenatide as a weight-loss therapy in extreme pediatric obesity: a randomized, controlled pilot study.
    Authors: Kelly AS, Metzig AM, Rudser KD, Fitch AK, Fox CK, Nathan BM, Deering MM, Schwartz BL, Abuzzahab MJ, Gandrud LM, Moran A, Billington CJ, Schwarzenberg SJ
    Obesity (Silver Spring), 2012;20(2):364-70.
    Species: Human
    Sample Type: Plasma
  41. A prospective study of circulating adipokine levels and risk of multiple myeloma.
    Authors: Hofmann J, Liao L, Pollak M, Wang Y, Pfeiffer R, Baris D, Andreotti G, Lan Q, Landgren O, Rothman N, Purdue M
    Blood, 2012;120(22):4418-20.
    Species: Human
    Sample Type: Plasma
  42. Prediction of gestational diabetes mellitus by maternal factors and biomarkers at 11 to 13 weeks.
    Authors: Nanda S, Savvidou M, Syngelaki A, Akolekar R, Nicolaides KH
    Prenat. Diagn., 2011;31(2):135-41.
    Species: Human
    Sample Type: Serum
  43. Association of angiopoietin-2, C-reactive protein and markers of obesity and insulin resistance with survival outcome in colorectal cancer.
    Authors: Volkova E, Willis JA, Wells JE, Robinson BA, Dachs GU, Currie MJ
    Br. J. Cancer, 2011;104(1):51-9.
    Species: Human
    Sample Type: Serum
  44. Adipocytokines and CD34 progenitor cells in Alzheimer's disease.
    Authors: Bigalke B, Schreitmuller B, Sopova K, Paul A, Stransky E, Gawaz M, Stellos K, Laske C
    PLoS ONE, 2011;6(5):e20286.
    Species: Human
    Sample Type: Plasma
  45. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
    Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
    Int J Obes (Lond), 2011;35(6):800-9.
    Species: Human
    Sample Type: Serum
  46. Inflammation associated with obesity: relationship with blood and bone marrow endothelial cells.
    Authors: McGuire TR, Brusnahan SK, Bilek LD, Jackson JD, Kessinger MA, Berger AM, Garvin KL, O'Kane BJ, Tuljapurkar SR, Sharp JG
    Obesity (Silver Spring), 2011;19(11):2130-6.
    Species: Human
    Sample Type: Plasma
  47. Exercise training improves sleep pattern and metabolic profile in elderly people in a time-dependent manner.
    Authors: Lira FS, Pimentel GD, Santos RV, Oyama LM, Damaso AR, Oller do Nascimento CM, Viana VA, Boscolo RA, Grassmann V, Santana MG, Esteves AM, Tufik S, de Mello MT
    Lipids Health Dis, 2011;10(0):113.
    Species: Human
    Sample Type: Plasma
  48. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010;59(12):3049-57.
    Species: Human
    Sample Type: Plasma
  49. An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach.
    Authors: Bakker GC, van Erk MJ, Pellis L, Wopereis S, Rubingh CM, Cnubben NH, Kooistra T, van Ommen B, Hendriks HF
    Am. J. Clin. Nutr., 2010;91(4):1044-59.
    Species: Human
    Sample Type: Plasma
  50. Exenatide affects circulating cardiovascular risk biomarkers independently of changes in body composition.
    Authors: Bunck MC, Diamant M, Eliasson B, Corner A, Shaginian RM, Heine RJ, Taskinen MR, Yki-Jarvinen H, Smith U
    Diabetes Care, 2010;33(8):1734-7.
    Species: Human
    Sample Type: Serum
  51. Serum adiponectin acutely after an ischemic stroke: implications for a long-lasting, suppressed anti-inflammatory role.
    Authors: Marousi S, Theodorou G, Karakantza M, Papathanasopoulos P, Ellul J
    Acta Neurol. Scand., 2010;121(4):277-84.
    Species: Human
    Sample Type: Serum
  52. Improvements in coronary heart disease risk indicators by alternate-day fasting involve adipose tissue modulations.
    Authors: Bhutani S, Klempel MC, Berger RA, Varady KA
    Obesity (Silver Spring), 2010;18(11):2152-9.
    Species: Human
    Sample Type: Plasma
  53. Are there socioeconomic inequalities in cardiovascular risk factors in childhood, and are they mediated by adiposity? Findings from a prospective cohort study.
    Authors: Howe LD, Galobardes B, Sattar N
    Int J Obes (Lond), 2010;34(7):1149-59.
    Species: Human
    Sample Type: Plasma
  54. First-trimester prediction of gestational diabetes mellitus: examining the potential of combining maternal characteristics and laboratory measures.
    Authors: Savvidou M, Nelson SM, Makgoba M, Messow CM, Sattar N, Nicolaides K
    Diabetes, 2010;59(12):3017-22.
    Species: Human
    Sample Type: Serum
  55. Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity.
    Authors: Chan DC, Watts GF, Gan S
    Arterioscler. Thromb. Vasc. Biol., 2010;30(5):1043-50.
    Species: Human
    Sample Type: Plasma
  56. Adiponectin and its association with bone mass accrual in childhood.
    Authors: Sayers A, Timpson NJ, Sattar N, Deanfield J, Hingorani AD, Davey-Smith G, Tobias JH
    J. Bone Miner. Res., 2010;25(10):2212-20.
    Species: Human
    Sample Type: Plasma
  57. HIV increases markers of cardiovascular risk: results from a randomized, treatment interruption trial.
    Authors: Calmy A, Gayet-Ageron A, Montecucco F, Nguyen A, Mach F, Burger F, Ubolyam S, Carr A, Ruxungtham K, Hirschel B, Ananworanich J,
    AIDS, 2009;23(8):929-39.
    Species: Human
    Sample Type: Plasma
  58. Association between the adiponectin promoter rs266729 gene variant and oxidative stress in patients with diabetes mellitus.
    Authors: Prior SL, Gable DR, Cooper JA, Bain SC, Hurel SJ, Humphries SE, Stephens JW
    Eur. Heart J., 2009;30(10):1263-9.
    Species: Human
    Sample Type: Plasma
  59. Plasma 25-hydroxyvitamin d is associated with markers of the insulin resistant phenotype in nondiabetic adults.
    Authors: Liu E, Meigs JB, Pittas AG, McKeown NM, Economos CD, Booth SL, Jacques PF
    J. Nutr., 2009;139(2):329-34.
    Species: Human
    Sample Type: Plasma
  60. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
    Authors: Miller M, Cho JY, Pham A, Ramsdell J, Broide DH
    J. Immunol., 2009;182(1):684-91.
    Species: Human
    Sample Type: BALF
  61. Serial changes in adiponectin and BNP in ACS patients: paradoxical associations with each other and with prognosis.
    Authors: Ang DS, Welsh P, Watt P, Nelson SM, Struthers A, Sattar N
    Clin. Sci., 2009;117(1):41-8.
    Species: Human
    Sample Type: Plasma
  62. Regulation of the fibrosis and angiogenesis promoter SPARC/osteonectin in human adipose tissue by weight change, leptin, insulin, and glucose.
    Authors: Kos K, Wong S, Tan B, Gummesson A, Jernas M, Franck N, Kerrigan D, Nystrom FH, Carlsson LM, Randeva HS, Pinkney JH, Wilding JP
    Diabetes, 2009;58(8):1780-8.
    Species: Human
    Sample Type: Serum
  63. Recombinant luteinizing hormone induces increased production of ovarian follicular adiponectin in vivo: implications for enhanced insulin sensitivity.
    Authors: Gutman G, Barak V, Maslovitz S, Amit A, Lessing JB, Geva E
    Fertil. Steril., 2009;91(5):1837-41.
    Species: Human
    Sample Type: Follicular Fluid
  64. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
    Diabetes Care, 2009;32(3):486-92.
    Species: Human
    Sample Type: Serum
  65. Resistin, adiponectin, and risk of heart failure the Framingham offspring study.
    Authors: Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB
    J. Am. Coll. Cardiol., 2009;53(9):754-62.
    Species: Human
    Sample Type: Plasma
  66. Environmental tobacco smoke and cardiometabolic risk in young children: results from a survey in south-west Germany.
    Authors: Nagel G, Arnold FJ, Wilhelm M, Link B, Zoellner I, Koenig W
    Eur. Heart J., 2009;30(15):1885-93.
    Species: Human
    Sample Type: Plasma
  67. Fish oil in combination with high or low intakes of linoleic acid lowers plasma triacylglycerols but does not affect other cardiovascular risk markers in healthy men.
    Authors: Damsgaard CT, Frokiaer H, Andersen AD, Lauritzen L
    J. Nutr., 2008;138(6):1061-6.
    Species: Human
    Sample Type: Plasma
  68. Retinol-binding protein 4 and lipocalin-2 in childhood and adolescent obesity: when children are not just "small adults".
    Authors: Kanaka-Gantenbein C, Margeli A, Pervanidou P, Sakka S, Mastorakos G, Chrousos GP, Papassotiriou I
    Clin. Chem., 2008;54(7):1176-82.
    Species: Human
    Sample Type: Serum
  69. Gene expression profiling of human skeletal muscle in response to stabilized weight loss.
    Authors: Larrouy D, Barbe P, Valle C, Dejean S, Pelloux V, Thalamas C, Bastard JP, Le Bouil A, Diquet B, Clement K, Langin D, Viguerie N
    Am. J. Clin. Nutr., 2008;88(1):125-32.
    Species: Human
    Sample Type: Plasma
  70. Factors contributing to the risk of cardiovascular disease reflected by plasma adiponectin: data from the coronary risk factors for atherosclerosis in women (CORA) study.
    Authors: Zyriax BC, Algenstaedt P, Hess UF, Schoffauer M, Bamberger C, Boeing H, Windler E
    Atherosclerosis, 2008;200(2):403-9.
    Species: Human
    Sample Type: Plasma
  71. Importance of the high-molecular-mass isoform of adiponectin in improved insulin sensitivity with rosiglitazone treatment in HIV disease.
    Authors: Qurashi S, Mynarcik DC, McNurlan MA, Ahn H, Ferris R, Gelato MC
    Clin. Sci., 2008;115(6):197-202.
    Species: Human
    Sample Type: Plasma
  72. Adiponectin plasma levels are increased by atorvastatin treatment in subjects at high cardiovascular risk.
    Authors: Blanco-Colio LM, Martin-Ventura JL, Gomez-Guerrero C, Masramon X, de Teresa E, Farsang C, Gaw A, Gensini G, Leiter LA, Langer A, Egido J
    Eur. J. Pharmacol., 2008;586(1):259-65.
    Species: Human
    Sample Type: Plasma
  73. Adiponectin gene variants are associated with insulin sensitivity in response to dietary fat consumption in Caucasian men.
    Authors: Perez-Martinez P, Lopez-Miranda J, Cruz-Teno C, Delgado-Lista J, Jimenez-Gomez Y, Fernandez JM, Gomez MJ, Marin C, Perez-Jimenez F, Ordovas JM
    J. Nutr., 2008;138(9):1609-14.
    Species: Human
    Sample Type: Plasma
  74. Association of IL-1ra and adiponectin with C-peptide and remission in patients with type 1 diabetes.
    Authors: Pfleger C, Mortensen HB, Hansen L, Herder C, Roep BO, Hoey H, Aanstoot HJ, Kocova M, Schloot NC
    Diabetes, 2008;57(4):929-37.
    Species: Human
    Sample Type: Serum
  75. Circulating levels of adiponectin and leptin at 23-25 weeks of pregnancy in women with impaired placentation and in those with established fetal growth restriction.
    Authors: Savvidou MD, Sotiriadis A, Kaihura C, Nicolaides KH, Sattar N
    Clin. Sci., 2008;115(7):219-24.
    Species: Human
    Sample Type: Plasma
  76. Nitrosative stress predicts the presence and severity of nonalcoholic fatty liver at different stages of the development of insulin resistance and metabolic syndrome: possible role of vitamin A intake.
    Authors: Musso G, Gambino R, De Michieli F, Biroli G, Premoli A, Pagano G, Bo S, Durazzo M, Cassader M
    Am. J. Clin. Nutr., 2007;86(3):661-71.
    Species: Human
    Sample Type: Serum
  77. Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.
    Authors: Farese RV, Sajan MP, Yang H, Li P, Mastorides S, Gower WR, Nimal S, Choi CS, Kim S, Shulman GI, Kahn CR, Braun U, Leitges M
    J. Clin. Invest., 2007;117(8):2289-301.
    Species: Human
    Sample Type: Serum
  78. Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure.
    Authors: Wannamethee SG, Whincup PH, Lennon L, Sattar N
    Arch. Intern. Med., 2007;167(14):1510-7.
    Species: Human
    Sample Type: Plasma
  79. Intake of phenol-rich virgin olive oil improves the postprandial prothrombotic profile in hypercholesterolemic patients.
    Authors: Ruano J, Lopez-Miranda J, de la Torre R, Delgado-Lista J, Fernandez J, Caballero J, Covas MI, Jimenez Y, Perez-Martinez P, Marin C, Fuentes F, Perez-Jimenez F
    Am. J. Clin. Nutr., 2007;86(2):341-6.
    Species: Human
    Sample Type: Plasma
  80. Relation of improvement in endothelium-dependent flow-mediated vasodilation after rosiglitazone to changes in asymmetric dimethylarginine, endothelin-1, and C-reactive protein in nondiabetic patients with the metabolic syndrome.
    Authors: Wang TD, Chen WJ, Cheng WC, Lin JW, Chen MF, Lee YT
    Am. J. Cardiol., 2006;98(8):1057-62.
    Species: Human
    Sample Type: Plasma
  81. Altered hepatic expression of SREBP-1 and PPARgamma is associated with liver injury in insulin-resistant lipodystrophic HIV-infected patients.
    Authors: Lemoine M, Barbu V, Girard PM, Kim M, Bastard JP, Wendum D, Paye F, Housset C, Capeau J, Serfaty L
    AIDS, 2006;20(3):387-95.
    Species: Human
    Sample Type: Serum
  82. Adiponectin and leptin in maternal serum, cord blood, and breast milk.
    Authors: Weyermann M, Beermann C, Brenner H, Rothenbacher D
    Clin. Chem., 2006;52(11):2095-102.
    Species: Human
    Sample Type: Serum
  83. Additive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patients.
    Authors: Koh KK, Quon MJ, Han SH, Chung WJ, Ahn JY, Kim JA, Lee Y, Shin EK
    Diabetes Care, 2006;29(2):195-201.
    Species: Human
    Sample Type: Plasma
  84. Non-esterified fatty acid concentrations are independently associated with hepatic steatosis in obese subjects.
    Authors: Holt HB, Wild SH, Wood PJ, Zhang J, Darekar AA, Dewbury K, Poole RB, Holt RI, Phillips DI, Byrne CD
    Diabetologia, 2006;49(1):141-8.
    Species: Human
    Sample Type: Serum
  85. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
    Authors: Iversen PO, Wiig H
    Clin. Cancer Res., 2005;11(19):6793-9.
    Species: Human
    Sample Type: Bone Marrow Fluid
  86. Adiponectin and other adipocytokines as predictors of markers of triglyceride-rich lipoprotein metabolism.
    Authors: Chan DC, Watts GF, Ng TW, Uchida Y, Sakai N, Yamashita S, Barrett PH
    Clin. Chem., 2005;51(3):578-85.
    Species: Human
    Sample Type: Plasma
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