Human VEGF Biotinylated Fluorokine Flow Cytometry Kit
Human VEGF Biotinylated Fluorokine Flow Cytometry Kit Summary
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Background: VEGF
VEGF (Vascular endothelial growth factor) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is required for regulating the proliferation, migration, and survival of embryonic endothelial cells and during wound healing and the female reproductive cycle in adults. Pathologically, it is involved in tumor development and tumor vascular leakage. VEGF binds to VEGF R1/Flt-1, VEGF R2/Flk-1/KDR, and Neuropilin-1. Multiple forms of VEGF are generated by alternative splicing and proteolysis.
Citations for Human VEGF Biotinylated Fluorokine Flow Cytometry Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans.
Authors: Krohne TU, Eter N, Holz FG, Meyer CH
Am. J. Ophthalmol., 2008-07-17;146(4):508-12. 2008-07-17
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Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
Authors: Narazaki M, Segarra M, Tosato G
Blood, 2008-02-13;111(8):4126-36. 2008-02-13
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Specific association of increased vascular endothelial growth factor expression and its receptors with macrophage differentiation of HL-60 leukemia cells.
Authors: Ohsaka A, Hirota-Komatsu S, Shibata M, Ezaki J, Shinohara F, Yoshida T
Biochem. Biophys. Res. Commun., 2008-02-07;368(3):543-9. 2008-02-07
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Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
Authors: Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV
Clin. Cancer Res., 2007-05-01;13(9):2643-50. 2007-05-01
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Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
J. Immunol., 2006-08-01;177(3):1460-9. 2006-08-01
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All three receptors for vascular endothelial growth factor (VEGF) are expressed on B-chronic lymphocytic leukemia (CLL) cells.
Authors: Bairey O, Boycov O, Kaganovsky E, Zimra Y, Shaklai M, Rabizadeh E
Leuk. Res., 2004-03-01;28(3):243-8. 2004-03-01
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Neuropilin-1 on hematopoietic cells as a source of vascular development.
Authors: Yamada Y, Oike Y, Ogawa H, Ito Y, Fujisawa H, Suda T, Takakura N
Blood, 2002-10-24;101(5):1801-9. 2002-10-24
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17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta.
Authors: Gargett CE, Zaitseva M, Bucak K, Chu S, Fuller PJ, Rogers PA
J. Clin. Endocrinol. Metab., 2002-09-01;87(9):4341-9. 2002-09-01
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