Human VEGF Luminex Performance Assay

Catalog #: LUH293 Datasheet / COA / SDS

Discontinued Product

LUH293 has been discontinued and is replaced by LUHM293.

R&D Systems Luminex High Performance Panel
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Human VEGF Luminex Performance Assay Summary

Assay Type bead-based multiplex assay for the Luminex® platform
Format 1 x 96-well microplate and antibody-coated beads
Analytes Detected Please see analyte list in assay customization tool below.
Performance Validation Luminex Assays are validated for use with cell culture supernatants, plasma and serum. All Luminex assays are tested for sensitivity, intra-assay precision, inter-assay precision and to ensure assay linearity for validated sample types. Antibody pairs are selected and tested to confirm the parallel detection of natural and recombinant standard protein and to ensure the accurate determination of target analytes within biological samples. Assays for each target analyte are screened against all target analytes to confirm low antibody cross-reactivity.

For standard curves, intra-assay and inter-assay precision, recovery, and linearity data for the different analyte-specific beads, please see product datasheets for corresponding individual Bead Sets (below).

Not finding your analyte of interest? View our complete Luminex offering in the full version of our Luminex Assay Customization Tool. We also offer Custom Luminex Services.

Which Luminex Assay is right for me?

Assays for the Luminex platform are offered as High Performance Assays or Assays. The Luminex High Performance Assays are fully validated panels with a focused selection of analytes. They are available in We Mix, You Mix, and Predetermined formats. The Luminex Assays allows for the maximum number of analytes in a multiplex and is supplied as a premixed kit. View a table comparing the features and benefits of these bead-based multiplex assays.

Background: VEGF

VEGF (Vascular endothelial growth factor) is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is required for regulating the proliferation, migration, and survival of embryonic endothelial cells and during wound healing and the female reproductive cycle in adults. Pathologically, it is involved in tumor development and tumor vascular leakage. VEGF binds to VEGF R1/Flt-1, VEGF R2/Flk-1/KDR, and Neuropilin-1. Multiple forms of VEGF are generated by alternative splicing and proteolysis.

Long Name
Vascular Endothelial Growth Factor
Entrez Gene IDs
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
Alternate Names
MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor

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Product Specific Notices
Luminex® is a registered trademark of Luminex Corporation.

Citations for Human VEGF Luminex Performance Assay

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

14 Citations: Showing 1 - 10
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  1. Role of serum levels of angiogenic cytokines in assessment of angiogenesis after stem cell therapy of diabetic patients with critical limb ischemia.
    Authors: Dubsky M, Jirkovska A, Bem R, Fejfarova V, Varga M, Kolesar L, Pagacova L, Sykova E, Jude E
    Cell Transplant, 2013-10-21;23(12):1517-23.
    Species: Human
    Sample Types: Serum
  2. Decreased plasma cytokines are associated with low platelet counts in aplastic anemia and immune thrombocytopenic purpura.
    J. Thromb. Haemost., 2012-08-01;10(8):1616-23.
    Species: Human
    Sample Types: Plasma
  3. Elevated cerebral spinal fluid cytokine levels in boys with cerebral adrenoleukodystrophy correlates with MRI severity.
    Authors: Lund TC, Stadem PS, Panoskaltsis-Mortari A, Raymond G, Miller WP, Tolar J, Orchard PJ
    PLoS ONE, 2012-02-16;7(2):e32218.
    Species: Human
    Sample Types: Serum
  4. Effects of methylprednisolone infusion on markers of inflammation, coagulation, and angiogenesis in early acute respiratory distress syndrome.
    Authors: Seam N, Meduri GU, Wang H, Nylen ES, Sun J, Schultz MJ, Tropea M, Suffredini AF
    Crit. Care Med., 2012-02-01;40(2):495-501.
    Species: Human
    Sample Types: Plasma
  5. Macrophage infiltration predicts a poor prognosis for human ewing sarcoma.
    Authors: Fujiwara T, Fukushi J, Yamamoto S, Matsumoto Y, Setsu N, Oda Y, Yamada H, Okada S, Watari K, Ono M, Kuwano M, Kamura S, Iida K, Okada Y, Koga M, Iwamoto Y
    Am. J. Pathol., 2011-07-21;179(3):1157-70.
    Species: Human
    Sample Types: Cell Culture Supernates
  6. Anti-Inflammatory Cytokines Predominate in Acute Human Plasmodium knowlesi Infections.
    Authors: Cox-Singh J, Singh B, Daneshvar C, Planche T, Parker-Williams J, Krishna S
    PLoS ONE, 2011-06-08;6(6):e20541.
    Species: Human
    Sample Types: Serum
  7. Potential biomarkers of osteonecrosis in Gaucher disease.
    Authors: Pavlova EV, Deegan PB, Tindall J, McFarlane I, Mehta A, Hughes D, Wraith JE, Cox TM
    Blood Cells Mol. Dis., 2010-11-13;46(1):27-33.
    Species: Human
    Sample Types: Serum
  8. Toll-like receptor 9 signaling by CpG-B oligodeoxynucleotides induces an apoptotic pathway in human chronic lymphocytic leukemia B cells.
    Authors: Liang X, Moseman EA, Farrar MA
    Blood, 2010-03-25;115(24):5041-52.
    Species: Human
    Sample Types: Cell Culture Supernates
  9. Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer.
    Authors: Haura EB, Tanvetyanon T, Chiappori A, Williams C, Simon G, Antonia S, Gray J, Litschauer S, Tetteh L, Neuger A, Song L, Rawal B, Schell MJ, Bepler G
    J. Clin. Oncol., 2010-02-08;28(8):1387-94.
    Species: Human
    Sample Types: Plasma
  10. Critical and differential roles of NKp46- and NKp30-activating receptors expressed by uterine NK cells in early pregnancy.
    Authors: El Costa H, Casemayou A, Aguerre-Girr M, Rabot M, Berrebi A, Parant O, Clouet-Delannoy M, Lombardelli L, Jabrane-Ferrat N, Rukavina D, Bensussan A, Piccinni MP, Le Bouteiller P, Tabiasco J
    J. Immunol., 2008-09-01;181(0):3009-17.
    Species: Human
    Sample Types: Cell Culture Supernates
  11. Simvastatin attenuates release of neutrophilic and remodeling factors from primary bronchial epithelial cells derived from stable lung transplant recipients.
    Authors: Murphy DM, Forrest IA, Corris PA, Johnson GE, Small T, Jones D, Fisher AJ, Egan JJ, Cawston TE, Ward C, Lordan JL
    Am. J. Physiol. Lung Cell Mol. Physiol., 2008-01-18;294(3):L592-9.
    Species: Human
    Sample Types: Cell Culture Supernates
  12. Positive correlation between estradiol and vascular endothelial growth factor but not fibroblast growth factor-2 in normal human breast tissue in vivo.
    Authors: Dabrosin C
    Clin. Cancer Res., 2005-11-15;11(22):8036-41.
    Species: Human
    Sample Types: Plasma
  13. Exercise acutely increases circulating endothelial progenitor cells and monocyte-/macrophage-derived angiogenic cells.
    Authors: Rehman J, Li J, Parvathaneni L, Karlsson G, Panchal VR, Temm CJ, Mahenthiran J, March KL
    J. Am. Coll. Cardiol., 2004-06-16;43(12):2314-8.
    Species: Human
    Sample Types: Plasma
  14. An in vitro tumor model: analysis of angiogenic factor expression after chemotherapy.
    Authors: Keyes K, Cox K, Treadway P, Mann L, Shih C, Faul MM, Teicher BA
    Cancer Res., 2002-10-01;62(19):5597-602.
    Species: Human
    Sample Types: Cell Culture Supernates

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