Human VEGF R2/KDR/Flk-1 PE-conjugated Antibody

(68 citations)
(1 Review)
  
  • Species Reactivity
    Human
  • Specificity
    Detects human VEGF R2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGF R1, rhVEGF R3 or recombinant mouse VEGF R2 is observed.
  • Source
    Monoclonal Mouse IgG1 Clone # 89106
  • Purification
    Protein A or G purified from hybridoma culture supernatant
  • Immunogen
    S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R2/KDR/Flk-1
    Ala20-Glu764
    Accession # P35968
  • Formulation
    Supplied in a saline solution containing BSA and Sodium Azide.
  • Label
    Phycoerythrin
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    10 µL/106 cells
    See below
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Data Examples
Detection of VEGF R2/KDR/Flk‑1 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R2/KDR/Flk‑1 PE‑conjugated Mono­clonal Antibody (Catalog # FAB357P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Protect from light. Do not freeze.
    • 12 months from date of receipt, 2 to 8 °C as supplied.
Background: VEGF R2/KDR/Flk-1

VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mature VEGF R2 is composed of a 745 aa extracellular domain, a 25 aa transmembrane domain and a 567 aa cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The recombinant soluble VEGF R2/Fc chimera binds VEGF with high affinity and is a potent VEGF antagonist.

  • References:
    1. Ferra, N. and R. Davis-Smyth (1997) Endocrine Reviews 18:4.
  • Long Name:
    Vascular Endothelial Growth Factor Receptor 2
  • Entrez Gene IDs:
    3791 (Human); 16542 (Mouse)
  • Alternate Names:
    CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

68 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. The blebbishield emergency program overrides chromosomal instability and phagocytosis checkpoints in cancer stem cells
    Authors: GG Jinesh, AM Kamat
    Cancer Res., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  2. Vildagliptin, but not glibenclamide, increases circulating endothelial progenitor cell number: a 12-month randomized controlled trial in patients with type 2 diabetes
    Authors: A Dei Cas, V Spigoni, M Cito, R Aldigeri, V Ridolfi, E Marchesi, M Marina, E Derlindati, R Aloe, RC Bonadonna, I Zavaroni
    Cardiovasc Diabetol, 2017;16(1):27.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  3. Effects of a New Nutraceutical Formulation (Berberine, Red Yeast Rice and Chitosan) on Non-HDL Cholesterol Levels in Individuals with Dyslipidemia: Results from a Randomized, Double Blind, Placebo-Controlled Study
    Authors: V Spigoni, R Aldigeri, M Antonini, MM Micheli, F Fantuzzi, A Fratter, M Pellizzato, E Derlindati, I Zavaroni, RC Bonadonna, A Dei Cas
    Int J Mol Sci, 2017;18(7):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  4. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017;20(7):1597-1608.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  5. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis
    Authors: Y Li, PM Brauer, J Singh, S Xhiku, K Yoganathan, JC Zúñiga-Pfl, MK Anderson
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  6. Increased serum levels of fractalkine and mobilisation of CD34(+)CD45(-) endothelial progenitor cells in systemic sclerosis
    Authors: A Benyamine, J Magalon, S Cointe, R Lacroix, L Arnaud, N Bardin, P Rossi, Y Francès, F Bernard-Gu, G Kaplanski, JR Harlé, PJ Weiller, P Berbis, D Braunstein, E Jouve, N Lesavre, F Couranjou, F Dignat-Geo, F Sabatier, P Paul, B Granel
    Arthritis Res. Ther, 2017;19(1):60.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  7. Dysregulation of ossification related microRNAs in circulating osteogenic progenitor cells obtained from patients with aortic stenosis
    Authors: K Takahashi, M Satoh, Y Takahashi, T Osaki, T Nasu, M Tamada, H Okabayashi, M Nakamura, Y Morino
    Clin Sci, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  8. Endothelial cell colony forming units derived from malignant breast diseases are resistant to tumor necrosis factor-?-induced apoptosis
    Sci Rep, 2016;6(0):37450.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  9. Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination
    Sci Rep, 2016;6(0):33162.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  10. MicroRNA-134 Contributes to Glucose-Induced Endothelial Cell Dysfunction and This Effect Can Be Reversed by Far-Infrared Irradiation.
    Authors: Wang H, Su S, Wang Y, Chang S, Liao K, Lo H, Chiu Y, Hsieh T, Huang T, Lin C, Cheng S, Cheng C
    PLoS ONE, 2016;11(1):e0147067.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  11. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
    Nature, 2016;535(7611):294-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  12. Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.
    Authors: Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J
    Stem Cells, 2015;33(1):133-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  13. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
    Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
    Clin Cancer Res, 2015;21(7):1652-64.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  14. The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study.
    Authors: West D, Campbell M, Gonzalez J, Walker M, Stevenson E, Ahmed F, Wijaya S, Shaw J, Weaver J
    Cardiovasc Diabetol, 2015;14(0):71.
    Species: Human
    Sample Type: Complex Sample Type
    Application: Flow
  15. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015;33(6):638-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  16. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
    Authors: Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, Nolan D, Elemento O, Wood B, Adair J, Rafii S, Kiem H
    J Clin Invest, 2015;125(3):1243-54.
    Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Type: Whole Cells
    Application: Flow
  17. Laminin promotes vascular network formation in 3D in vitro collagen scaffolds by regulating VEGF uptake.
    Authors: Stamati K, Priestley J, Mudera V, Cheema U
    Exp Cell Res, 2014;327(1):68-77.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  18. Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer.
    Authors: Van't Hull E, Bron S, Henry L, Ifticene-Treboux A, Turrini R, Coukos G, Delaloye J, Doucey M
    Oncoimmunology, 2014;3(0):e29080.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  19. The relationship between endothelial progenitor cell populations and epicardial and microvascular coronary disease-a cellular, angiographic and physiologic study.
    Authors: Chan, Kim H, Simpson, Philippa, Yong, Andy S, Dunn, Louise L, Chawantanpipat, Chirapan, Hsu, Chijen, Yu, Young, Keech, Anthony, Celermajer, David S, Ng, Martin K
    PLoS ONE, 2014;9(4):e93980.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  20. IFNalpha serum levels are associated with endothelial progenitor cells imbalance and disease features in rheumatoid arthritis patients.
    Authors: Rodriguez-Carrio J, de Paz B, Lopez P, Prado C, Alperi-Lopez M, Ballina-Garcia F, Suarez A
    PLoS ONE, 2014;9(1):e86069.
    Species: Human
    Sample Type: Whole Blood
    Application: Flow
  21. Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.
    Authors: To C, Farnsworth R, Vail M, Chheang C, Gargett C, Murone C, Llerena C, Major A, Scott A, Janes P, Lackmann M
    PLoS ONE, 2014;9(11):e112106.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  22. Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia.
    Authors: Zucco L, Zhang Q, Kuliszewski M, Kandic I, Faughnan M, Stewart D, Kutryk M
    PLoS ONE, 2014;9(2):e89927.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  23. Characterization of circulating and endothelial progenitor cells in patients with extreme-duration type 1 diabetes.
    Authors: Hernandez S, Gong J, Chen L, Wu I, Sun J, Keenan H, King G
    Diabetes Care, 2014;37(8):2193-201.
    Species: Human
    Sample Type: Whole Blood
    Application: Flow
  24. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
    Authors: Orlova, Valeria, Drabsch, Yvette, Freund, Christia, Petrus-Reurer, Sandra, van den Hil, Francijn, Muenthaisong, Suchitra, Dijke, Peter Te, Mummery, Christin
    Arterioscler Thromb Vasc Biol, 2014;34(1):177-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  25. Migratory activity of circulating mononuclear cells is associated with cardiovascular mortality in type 2 diabetic patients with critical limb ischemia.
    Authors: Spinetti G, Specchia C, Fortunato O, Sangalli E, Clerici G, Caminiti M, Airoldi F, Losa S, Emanueli C, Faglia E, Madeddu P
    Diabetes Care, 2014;37(5):1410-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  26. Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells.
    Authors: Kraan, J, van den Broek, P, Verhoef, C, Grunhagen, D J, Taal, W, Gratama, J W, Sleijfer, S
    Br J Cancer, 2014;111(1):149-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  27. Endothelial progenitor cells in morbid obesity.
    Authors: Graziani F, Leone A, Basile E, Cialdella P, Tritarelli A, Bona R, Liuzzo G, Nanni G, Iaconelli A, Iaconelli A, Mingrone G, Biasucci L, Crea F
    Circ J, 2014;78(4):977-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  28. Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
    Authors: Orlova, Valeria, van den Hil, Francijn, Petrus-Reurer, Sandra, Drabsch, Yvette, Ten Dijke, Peter, Mummery, Christin
    Nat Protoc, 2014;9(6):1514-31.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  29. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R.
    Authors: Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, Stella A, Jensen-Jarolim E, Holler C, Wacheck V, Pehamberger H, Valent P
    PLoS ONE, 2014;9(1):e84417.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  30. Efficiency of statin treatment on EPC recruitment depends on baseline EPC titer and does not improve angiographic outcome in coronary artery disease patients treated with the Genous stent.
    Authors: den Dekker W, Houtgraaf J, Rowland S, Ligtenberg E, de Boer S, de Jong R, de Winter R, den Heijer P, Zijlstra F, Serruys P, Cheng C, Duckers H
    Cell Transplant, 2014;23(12):1525-35.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  31. The dipeptidyl peptidase-4 inhibitor saxagliptin improves function of circulating pro-angiogenic cells from type 2 diabetic patients.
    Authors: Poncina N, Albiero M, Menegazzo L, Cappellari R, Avogaro A, Fadini G
    Cardiovasc Diabetol, 2014;13(0):92.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  32. Diabetes impairs stem cell and proangiogenic cell mobilization in humans.
    Authors: Fadini G, Albiero M, Vigili de Kreutzenberg S, Boscaro E, Cappellari R, Marescotti M, Poncina N, Agostini C, Avogaro A
    Diabetes Care, 2013;36(4):943-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  33. An affordable method to obtain cultured endothelial cells from peripheral blood.
    Authors: Bueno-Beti C, Novella S, Lazaro-Franco M, Perez-Cremades D, Heras M, Sanchis J, Hermenegildo C
    J Cell Mol Med, 2013;17(11):1475-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  34. The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence.
    Authors: Grimaldi A, Balestrieri M, D'Onofrio N, Di Domenico G, Nocera C, Lamberti M, Tonini G, Zoccoli A, Santini D, Caraglia M, Pantano F
    PLoS ONE, 2013;8(11):e79658.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  35. CXCR4 positive and angiogenic monocytes in myocardial infarction.
    Thromb Haemost, 2013;109(2):255-62.
    Species: Human
    Sample Type: Whole Blood
    Application: Flow
  36. Circulating endothelial progenitor cells decrease in infants with bronchopulmonary dysplasia and increase after inhaled nitric oxide.
    Authors: Qi, Yuanyuan, Jiang, Qian, Chen, Chao, Cao, Yun, Qian, Liling
    PLoS ONE, 2013;8(11):e79060.
    Species: Human
    Sample Type: Plasma
    Application: Flow
  37. Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy.
    Authors: Vereb Z, Lumi X, Andjelic S, Globocnik-Petrovic M, Urbancic M, Hawlina M, Facsko A, Petrovski G
    Biomed Res Int, 2013;2013(0):492376.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  38. Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.
    Authors: Albert R, Vereb Z, Csomos K, Moe M, Johnsen E, Olstad O, Nicolaissen B, Rajnavolgyi E, Fesus L, Berta A, Petrovski G
    PLoS ONE, 2012;7(10):e47187.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  39. Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.
    Authors: Pelosi E, Castelli G, Martin-Padura I, Bordoni V, Santoro S, Conigliaro A, Cerio A, De Santis Puzzonia M, Marighetti P, Biffoni M, Alonzi T, Amicone L, Alcalay M, Bertolini F, Testa U, Tripodi M
    PLoS ONE, 2012;7(12):e51109.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  40. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC.
    Authors: Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, Schrezenmeier H
    PLoS ONE, 2012;7(8):e43255.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  41. Successful In Vitro Expansion and Differentiation of Cord Blood Derived CD34+ Cells into Early Endothelial Progenitor Cells Reveals Highly Differential Gene Expression.
    Authors: Ahrens I, Domeij H, Topcic D
    PLoS ONE, 2011;6(8):e23210.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  42. Comparison of endothelial progenitor cell function in type 2 diabetes with good and poor glycemic control.
    Authors: Churdchomjan, Worachat, Kheolamai, Pakpoom, Manochantr, Sirikul, Tapanadechopone, Pirath, Tantrawatpan, Chairat, U-Pratya, Yaowalak, Issaragrisil, Surapol
    BMC Endocr Disord, 2010;10(0):5.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  43. Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man.
    Authors: Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
    Bone, 2010;46(3):673-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  44. VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.
    Authors: Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M
    Eur. J. Immunol., 2010;40(1):197-203.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  45. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.
    Authors: Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G
    Blood, 2010;116(16):3099-107.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  46. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Authors: Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV
    Oncogene, 2010;29(20):2938-49.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  47. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells.
    Authors: Ball SG, Bayley C, Shuttleworth CA, Kielty CM
    Biochem. J., 2010;427(1):29-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  48. Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
    Authors: Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U
    Br. J. Haematol., 2009;145(3):399-411.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  49. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
    Authors: Narazaki M, Segarra M, Tosato G
    Blood, 2008;111(8):4126-36.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  50. Microtubule-targeted drugs inhibit VEGF receptor-2 expression by both transcriptional and post-transcriptional mechanisms.
    Authors: Meissner M, Pinter A, Michailidou D, Hrgovic I, Kaprolat N, Stein M, Holtmeier W, Kaufmann R, Gille J
    J. Invest. Dermatol., 2008;128(8):2084-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  51. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  52. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
    Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
    Exp. Hematol., 2008;36(5):545-558.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  53. Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation.
    Authors: Kern J, Bauer M, Rychli K, Wojta J, Ritsch A, Gastl G, Gunsilius E, Untergasser G
    Arterioscler. Thromb. Vasc. Biol., 2008;28(3):478-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  54. Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.
    Authors: Westerweel PE, Visseren FL, Hajer GR, Olijhoek JK, Hoefer IE, de Bree P, Rafii S, Doevendans PA, Verhaar MC
    Eur. Heart J., 2008;29(22):2808-17.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  55. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
    Authors: Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
    J. Cell. Physiol., 2008;217(1):261-80.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Whole Cells
    Application: Flow
  56. Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.
    Authors: Thill M, Strunnikova NV, Berna MJ, Gordiyenko N, Schmid K, Cousins SW, Thompson DJ, Csaky KG
    Invest. Ophthalmol. Vis. Sci., 2008;49(6):2696-708.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  57. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
    Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
    Blood, 2007;111(4):1933-41.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  58. Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
    Authors: Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV
    Clin. Cancer Res., 2007;13(9):2643-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  59. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007;177(3):489-500.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  60. VEGFR2 expressing circulating (progenitor) cell populations in volunteers and cancer patients.
    Authors: Vroling L, Yuana Y, Schuurhuis GJ, van Hinsbergh VW, Gundy C, de Haas R, van Cruijsen H, Boven E, Hoekman K, Broxterman HJ
    Thromb. Haemost., 2007;98(2):440-50.
    Species: Human
    Sample Type: Whole Blood
    Application: Flow
  61. Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
    Authors: Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J
    J. Clin. Invest., 2007;117(11):3369-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  62. Increased circulating endothelial progenitor cells in septic patients: correlation with survival.
    Authors: Rafat N, Hanusch C, Brinkkoetter PT, Schulte J, Brade J, Zijlstra JG, van der Woude FJ, van Ackern K, Yard BA, Beck GCh
    Crit. Care Med., 2007;35(7):1677-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  63. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus.
    Authors: Lee PY, Li Y, Richards HB, Chan FS, Zhuang H, Narain S, Butfiloski EJ, Sobel ES, Reeves WH, Segal MS
    Arthritis Rheum., 2007;56(11):3759-69.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  64. Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
    Authors: Wang CH, Verma S, Hsieh IC, Chen YJ, Kuo LT, Yang NI, Wang SY, Wu MY, Hsu CM, Cheng CW, Cherng WJ
    J. Mol. Cell. Cardiol., 2006;41(1):34-43.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Flow
  65. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
    Authors: Narazaki M, Tosato G
    Blood, 2006;107(10):3892-901.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  66. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
    Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
    Br. J. Haematol., 2006;135(5):703-14.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  67. Expansion of human SCID-repopulating cells under hypoxic conditions.
    Authors: Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC
    J. Clin. Invest., 2003;112(1):126-35.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
  68. Structural and functional studies of the endothelial activation antigen endothelial leucocyte adhesion molecule-1 using a panel of monoclonal antibodies.
    Authors: Pigott R, Needham LA, Edwards RM
    J. Immunol., 1991;147(1):130-5.
    Species: Human
    Sample Type: Whole Cells
    Application: Flow
Expand to show all 68 Citations
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Average Rating: 4 (Based on 1 review)

Have you used Human VEGF R2/KDR/Flk-1 PE-conjugated Antibody?

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We have 1 review tested in 1 application: Flow Cytometry.

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Flow Cytometry Human VEGF R2/KDR/Flk-1 PE-conjugated Antibody FAB357P
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Flow Cytometry Human VEGF R2/KDR/Flk-1 PE-conjugated Antibody FAB357P
Flow Cytometry: Human VEGF R2/KDR/Flk-1 PE-conjugated Antibody [FAB357P]

Summary

ApplicationFlow Cytometry
Sample TestedH1 human embryonic stem cells derived mesoderm
SpeciesHuman

Other Experimental Details

Other Experimental DetailsH1 cells were treated with ChIR 6uM for 48h. Then, 1x106 cells were incubated for 45min with 10ul of KDR-PE antibody or Igg-PE antibody and analyzed using LSRII cytometer.

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