Human VEGFR2/KDR/Flk-1 PE-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB357P-100
FAB357P-025
Detection of VEGF R2/KDR/Flk‑1 in HUVEC Human Cells by Flow Cytometry.
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Citations (97)
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Human VEGFR2/KDR/Flk-1 PE-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human VEGF R2/KDR/Flk-1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) VEGF R1, rhVEGF R3 or recombinant mouse VEGF R2 is observed.
Source
Monoclonal Mouse IgG1 Clone # 89106
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGF R2/KDR/Flk-1
Ala20-Glu764
Accession # P35968
Formulation
Supplied in a saline solution containing BSA and Sodium Azide.
Label
Phycoerythrin (Excitation= 488 nm, Emission= 565-605 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
10 µL/106 cells
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Flow Cytometry Detection of VEGF R2/KDR/Flk-1 antibody in HUVEC Human Cells antibody by Flow Cytometry. View Larger

Detection of VEGF R2/KDR/Flk‑1 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human VEGF R2/KDR/Flk-1 PE-conjugated Mono-clonal Antibody (Catalog # FAB357P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: VEGFR2/KDR/Flk-1

VEGF R2 (KDR/Flk-1), VEGF R1 (Flt-1) and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mature VEGF R2 is composed of a 745 aa extracellular domain, a 25 aa transmembrane domain and a 567 aa cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The recombinant soluble VEGF R2/Fc chimera binds VEGF with high affinity and is a potent VEGF antagonist.

References
  1. Ferra, N. and R. Davis-Smyth (1997) Endocrine Reviews 18:4.
Long Name
Vascular Endothelial Growth Factor Receptor 2
Entrez Gene IDs
3791 (Human); 16542 (Mouse)
Alternate Names
CD309 antigen; CD309; EC 2.7.10; EC 2.7.10.1; Fetal liver kinase 1; fetal liver kinase-1; Flk1; Flk-1; FLK1tyrosine kinase growth factor receptor; KDR; kinase insert domain receptor (a type III receptor tyrosine kinase); Kinase insert domain receptor; KRD1; Ly73; Protein-tyrosine kinase receptor flk-1; soluble VEGFR2; vascular endothelial growth factor receptor 2; VEGF R2; VEGFR; VEGFR2; VEGFR-2

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Citations for Human VEGFR2/KDR/Flk-1 PE-conjugated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

97 Citations: Showing 1 - 10
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  1. Impaired repair properties of endothelial colony-forming cells in patients with granulomatosis with polyangiitis
    Authors: APT Del Rio, JO Frade-Guan, S Ospina-Pri, BKL Duarte, MB Bertolo, MC Ozelo, Z Sachetto
    Journal of Cellular and Molecular Medicine, 2022;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  2. Functional Impairment of Endothelial Colony Forming Cells (ECFC) in Patients with Severe Atherosclerotic Cardiovascular Disease (ASCVD)
    Authors: S Simoncini, S Toupance, C Labat, S Gautier, C Dumoulin, L Arnaud, MG Stathopoul, S Visvikis-S, PM Rossi, A Benetos, F Dignat-Geo, F Sabatier
    International Journal of Molecular Sciences, 2022;23(16):.
    Species: Human
    Sample Types: Whole Cells
  3. CD1d expression demarcates CDX4+ hemogenic mesoderm with definitive hematopoietic potential
    Authors: J Philip Cre, SA Luff, H Yu, CM Sturgeon
    Stem Cell Research, 2022;62(0):102808.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Role of endothelial colony forming cells (ECFCs) Tetrahydrobiopterin (BH4) in determining ECFCs functionality in coronary artery disease (CAD) patients
    Authors: A Sen, A Singh, A Roy, S Mohanty, N Naik, M Kalaivani, L Ramakrishn
    Scientific Reports, 2022;12(1):3076.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Specific mesoderm subset derived from human pluripotent stem cells ameliorates microvascular pathology in type 2 diabetic mice
    Authors: CH Gil, D Chakrabort, CP Vieira, N Prasain, SL Calzi, SD Fortmann, P Hu, K Banno, M Jamal, C Huang, MS Sielski, Y Lin, X Huang, MD Dupont, JL Floyd, R Prasad, ALF Longhini, TJ McGill, HM Chung, MP Murphy, DN Kotton, ME Boulton, MC Yoder, MB Grant
    Science Advances, 2022;8(9):eabm5559.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  6. Reduced angiovasculogenic and increased inflammatory profiles of cord blood cells in severe but not mild preeclampsia
    Authors: S Cho, YD Sohn, S Kim, A Rajakumar, ML Badell, N Sidell, YS Yoon
    Scientific Reports, 2021;11(1):3630.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  7. Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
    Authors: Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, O Elemento, S Chen, D Huangfu, T Evans
    Cell Reports, 2021;37(10):110095.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  8. Rationale and design of the granulocyte-macrophage colony stimulating factor in peripheral arterial disease (GPAD-3) study
    Authors: A Mehta, K Mavromatis, YA Ko, SC Rogers, DS Dhindsa, C Goodwin, R Patel, MA Martini, M Prasad, A Mokhtari, IG Hesaroieh, SC Frohwein, MH Kutner, A Harzand, BJ Wells, Y Duwayri, O Alabi, RR Rajani, LP Brewster, EK Waller, AA Quyyumi
    Contemp Clin Trials, 2020;91(0):105975.
    Species: Human
    Sample Types: Whole Blood
    Applications: Neutralization
  9. Tropomyosin 1 genetically constrains in vitro hematopoiesis
    Authors: CS Thom, CD Jobaliya, K Lorenz, JA Maguire, A Gagne, P Gadue, DL French, BF Voight
    BMC Biol., 2020;18(1):52.
    Species: Human
    Sample Types:
    Applications: Flow
  10. Predicting Angiogenesis by Endothelial Progenitor Cells Relying on In-Vitro Function Assays and VEGFR-2 Expression Levels
    Authors: N Sabbah, T Tamari, R Elimelech, O Doppelt, U Rudich, H Zigdon-Gil
    Biomolecules, 2019;9(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  11. Systemic microvascular rarefaction is correlated with dysfunction of late endothelial progenitor cells in mild hypertension: a substudy of EXCAVATION-CHN1
    Authors: J Liang, Y Li, L Chen, W Xia, G Wu, X Tong, C Su, J He, X Lin, J Tao
    J Transl Med, 2019;17(1):368.
    Species: Human
    Sample Types: Whole Cell
    Applications: Flow Cytometry
  12. Effects of exergaming in postmenopausal women with high cardiovascular risk: A randomized controlled trial
    Authors: EA Jo, SS Wu, HR Han, JJ Park, SJ Park, KI Cho
    Clin Cardiol, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  13. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
    Cell Rep, 2019;27(2):599-615.e12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  14. Effect of intensive multifactorial treatment on vascular progenitor cells in hypertensive patients
    Authors: C Maroun-Eid, A Ortega-Her, J Modrego, M Abad-Cardi, JA García-Don, L Reinares, N Martell-Cl, D Gómez-Garr
    PLoS ONE, 2018;13(1):e0190494.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  15. Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy
    Authors: H Jia, C Thelwell, P Dilger, C Bird, S Daniels, M Wadhwa
    Thromb. Res., 2018;163(0):105-116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  16. Linking cell function with perfusion: insights from the transcatheter delivery of bone marrow-derived CD133+ cells in ischemic refractory cardiomyopathy trial (RECARDIO)
    Authors: B Bassetti, C Carbucicch, V Catto, E Gambini, E Rurali, A Bestetti, G Gaipa, D Belotti, F Celeste, M Parma, S Righetti, L Biava, M Arosio, A Bonomi, P Agostoni, P Scacciatel, F Achilli, G Pompilio
    Stem Cell Res Ther, 2018;9(1):235.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  17. Anti-Angiogenic miR-222, miR-195, and miR-21a Plasma Levels in T1DM Are Improved by Metformin Therapy, Thus Elucidating Its Cardioprotective Effect: The MERIT Study
    Authors: FW Ahmed, S Bakhashab, IT Bastaman, RE Crossland, M Glanville, JU Weaver
    Int J Mol Sci, 2018;19(10):.
    Species: Human
    Sample Types: Whole Blood
    Applications: Flow Cytometry
  18. Preparation of iPS cell-derived CD31+ endothelial cells using three-dimensional suspension culture
    Authors: S Masuda, K Matsuura, T Shimizu
    Regen Ther, 2018;9(0):1-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Selection
  19. Putative mechanisms Underlying Myocardial infarction onset and Emotions (PUME): a randomised controlled study protocol
    Authors: I Ensari, MM Burg, KM Diaz, J Fu, AT Duran, JM Suls, JA Sumner, R Monane, JE Julian, S Zhao, WF Chaplin, D Shimbo
    BMJ Open, 2018;8(5):e020525.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  20. Quality-Quantity Control Culture Enhances Vasculogenesis and Wound Healing Efficacy of Human Diabetic Peripheral Blood CD34+ Cells
    Authors: R Tanaka, H Masuda, S Fujimura, R Ito-Hirano, K Arita, Y Kakinuma, H Hagiwara, M Kado, A Hayashi, T Mita, T Ogawa, H Watada, H Mizuno, N Sawada, T Asahara
    Stem Cells Transl Med, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  21. Circulating microparticle subpopulations in systemic lupus erythematosus are affected by disease activity
    Authors: P López, J Rodríguez-, A Martínez-Z, L Caminal-Mo, A Suárez
    Int. J. Cardiol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  22. A quantitative method for screening and identifying molecular targets for nanomedicine
    Authors: P Guo, J Yang, DR Bielenberg, D Dillon, D Zurakowski, MA Moses, DT Auguste
    J Control Release, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  23. Increased serum levels of fractalkine and mobilisation of CD34(+)CD45(-) endothelial progenitor cells in systemic sclerosis
    Authors: A Benyamine, J Magalon, S Cointe, R Lacroix, L Arnaud, N Bardin, P Rossi, Y Francès, F Bernard-Gu, G Kaplanski, JR Harlé, PJ Weiller, P Berbis, D Braunstein, E Jouve, N Lesavre, F Couranjou, F Dignat-Geo, F Sabatier, P Paul, B Granel
    Arthritis Res. Ther, 2017;19(1):60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  24. Vildagliptin, but not glibenclamide, increases circulating endothelial progenitor cell number: a 12-month randomized controlled trial in patients with type 2 diabetes
    Authors: A Dei Cas, V Spigoni, M Cito, R Aldigeri, V Ridolfi, E Marchesi, M Marina, E Derlindati, R Aloe, RC Bonadonna, I Zavaroni
    Cardiovasc Diabetol, 2017;16(1):27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  25. Effects of Chronic Exercise on Endothelial Progenitor Cells and Microparticles in Professional Runners
    Authors: CRO Bittencour, MCO Izar, CN França, VL Schwerz, RMDS Póvoa, FAH Fonseca
    Arq. Bras. Cardiol., 2017;108(3):212-216.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  26. Hydrogen Sulfide-Preconditioning of Human Endothelial Progenitor Cells Transplantation Improves Re-Endothelialization in Nude Mice with Carotid Artery Injury
    Authors: X Ke, J Zou, Q Hu, X Wang, C Hu, R Yang, J Liang, X Shu, R Nie, C Peng
    Cell. Physiol. Biochem., 2017;43(1):308-319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  27. VEGF-induced intracellular Ca2+ oscillations are down-regulated and do not stimulate angiogenesis in breast cancer-derived endothelial colony forming cells
    Authors: F Lodola, U Laforenza, F Cattaneo, FA Ruffinatti, V Poletto, M Massa, R Tancredi, E Zuccolo, DA Khdar, A Riccardi, M Biggiogera, V Rosti, G Guerra, F Moccia
    Oncotarget, 2017;8(56):95223-95246.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  28. Targeted Disruption of TCF12 Reveals HEB as Essential in Human Mesodermal Specification and Hematopoiesis
    Authors: Y Li, PM Brauer, J Singh, S Xhiku, K Yoganathan, JC Zúñiga-Pfl, MK Anderson
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  29. The blebbishield emergency program overrides chromosomal instability and phagocytosis checkpoints in cancer stem cells
    Authors: GG Jinesh, AM Kamat
    Cancer Res., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  30. Sex Differences in Circulating Progenitor Cells
    Authors: ML Topel, SS Hayek, YA Ko, PB Sandesara, A Samman Tah, I Hesaroieh, E Mahar, GS Martin, EK Waller, AA Quyyumi
    J Am Heart Assoc, 2017;6(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  31. Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis
    Authors: NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry
    Cell Rep, 2017;20(7):1597-1608.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  32. Effects of a New Nutraceutical Formulation (Berberine, Red Yeast Rice and Chitosan) on Non-HDL Cholesterol Levels in Individuals with Dyslipidemia: Results from a Randomized, Double Blind, Placebo-Controlled Study
    Authors: V Spigoni, R Aldigeri, M Antonini, MM Micheli, F Fantuzzi, A Fratter, M Pellizzato, E Derlindati, I Zavaroni, RC Bonadonna, A Dei Cas
    Int J Mol Sci, 2017;18(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  33. Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination
    Sci Rep, 2016;6(0):33162.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  34. Somatic GNAQ Mutation is Enriched in Brain Endothelial Cells in�Sturge-Weber Syndrome
    Authors: Lan Huang
    Pediatr. Neurol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  35. MicroRNA-134 Contributes to Glucose-Induced Endothelial Cell Dysfunction and This Effect Can Be Reversed by Far-Infrared Irradiation.
    Authors: Wang H, Su S, Wang Y, Chang S, Liao K, Lo H, Chiu Y, Hsieh T, Huang T, Lin C, Cheng S, Cheng C
    PLoS ONE, 2016;11(1):e0147067.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  36. Endothelial cell colony forming units derived from malignant breast diseases are resistant to tumor necrosis factor-?-induced apoptosis
    Sci Rep, 2016;6(0):37450.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  37. Cell therapy in critical limb ischemia: A comprehensive analysis of two cell therapy products
    Authors: Claire Tournois
    Cytotherapy, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  38. BMP4/Id2 signaling pathway is a novel therapeutic target for late outgrowth endothelial progenitor cell-mediated endothelial injury repair
    Authors: Jun Tao
    Int. J. Cardiol., 2016;228(0):796-804.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  39. Dysregulation of ossification related microRNAs in circulating osteogenic progenitor cells obtained from patients with aortic stenosis
    Authors: K Takahashi, M Satoh, Y Takahashi, T Osaki, T Nasu, M Tamada, H Okabayashi, M Nakamura, Y Morino
    Clin Sci, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  40. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
    Nature, 2016;535(7611):294-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  41. Vascular niche promotes hematopoietic multipotent progenitor formation from pluripotent stem cells.
    Authors: Gori J, Butler J, Chan Y, Chandrasekaran D, Poulos M, Ginsberg M, Nolan D, Elemento O, Wood B, Adair J, Rafii S, Kiem H
    J Clin Invest, 2015;125(3):1243-54.
    Species: Primate - Macaca nemestrina (Southern Pig-tailed Macaque)
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  42. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
    Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
    Clin Cancer Res, 2015;21(7):1652-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  43. Generation of articular chondrocytes from human pluripotent stem cells.
    Authors: Craft A, Rockel J, Nartiss Y, Kandel R, Alman B, Keller G
    Nat Biotechnol, 2015;33(6):638-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  44. The inflammation, vascular repair and injury responses to exercise in fit males with and without Type 1 diabetes: an observational study.
    Authors: West D, Campbell M, Gonzalez J, Walker M, Stevenson E, Ahmed F, Wijaya S, Shaw J, Weaver J
    Cardiovasc Diabetol, 2015;14(0):71.
    Species: Human
    Sample Types: Complex Sample Type
    Applications: Flow Cytometry
  45. Glucose transporter 1-positive endothelial cells in infantile hemangioma exhibit features of facultative stem cells.
    Authors: Huang L, Nakayama H, Klagsbrun M, Mulliken J, Bischoff J
    Stem Cells, 2015;33(1):133-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  46. Endothelial CD276 (B7-H3) expression is increased in human malignancies and distinguishes between normal and tumour-derived circulating endothelial cells.
    Authors: Kraan, J, van den Broek, P, Verhoef, C, Grunhagen, D J, Taal, W, Gratama, J W, Sleijfer, S
    Br J Cancer, 2014;111(1):149-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  47. Endothelial progenitor cells in morbid obesity.
    Authors: Graziani F, Leone A, Basile E, Cialdella P, Tritarelli A, Bona R, Liuzzo G, Nanni G, Iaconelli A, Iaconelli A, Mingrone G, Biasucci L, Crea F
    Circ J, 2014;78(4):977-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  48. Circulating angiogenic cell dysfunction in patients with hereditary hemorrhagic telangiectasia.
    Authors: Zucco L, Zhang Q, Kuliszewski M, Kandic I, Faughnan M, Stewart D, Kutryk M
    PLoS ONE, 2014;9(2):e89927.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  49. IFNalpha serum levels are associated with endothelial progenitor cells imbalance and disease features in rheumatoid arthritis patients.
    Authors: Rodriguez-Carrio J, de Paz B, Lopez P, Prado C, Alperi-Lopez M, Ballina-Garcia F, Suarez A
    PLoS ONE, 2014;9(1):e86069.
    Species: Human
    Sample Types: Whole Blood
    Applications: Flow Cytometry
  50. The relationship between endothelial progenitor cell populations and epicardial and microvascular coronary disease-a cellular, angiographic and physiologic study.
    Authors: Chan, Kim H, Simpson, Philippa, Yong, Andy S, Dunn, Louise L, Chawantanpipat, Chirapan, Hsu, Chijen, Yu, Young, Keech, Anthony, Celermajer, David S, Ng, Martin K
    PLoS ONE, 2014;9(4):e93980.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  51. Efficiency of statin treatment on EPC recruitment depends on baseline EPC titer and does not improve angiographic outcome in coronary artery disease patients treated with the Genous stent.
    Authors: den Dekker W, Houtgraaf J, Rowland S, Ligtenberg E, de Boer S, de Jong R, de Winter R, den Heijer P, Zijlstra F, Serruys P, Cheng C, Duckers H
    Cell Transplant, 2014;23(12):1525-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  52. Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
    Authors: Orlova, Valeria, van den Hil, Francijn, Petrus-Reurer, Sandra, Drabsch, Yvette, Ten Dijke, Peter, Mummery, Christin
    Nat Protoc, 2014;9(6):1514-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  53. The dipeptidyl peptidase-4 inhibitor saxagliptin improves function of circulating pro-angiogenic cells from type 2 diabetic patients.
    Authors: Poncina N, Albiero M, Menegazzo L, Cappellari R, Avogaro A, Fadini G
    Cardiovasc Diabetol, 2014;13(0):92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  54. Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R.
    Authors: Mirkina I, Hadzijusufovic E, Krepler C, Mikula M, Mechtcheriakova D, Strommer S, Stella A, Jensen-Jarolim E, Holler C, Wacheck V, Pehamberger H, Valent P
    PLoS ONE, 2014;9(1):e84417.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  55. Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer.
    Authors: Van't Hull E, Bron S, Henry L, Ifticene-Treboux A, Turrini R, Coukos G, Delaloye J, Doucey M
    Oncoimmunology, 2014;3(0):e29080.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  56. Characterization of circulating and endothelial progenitor cells in patients with extreme-duration type 1 diabetes.
    Authors: Hernandez S, Gong J, Chen L, Wu I, Sun J, Keenan H, King G
    Diabetes Care, 2014;37(8):2193-201.
    Species: Human
    Sample Types: Whole Blood
    Applications: Flow Cytometry
  57. Hypoxia-controlled EphA3 marks a human endometrium-derived multipotent mesenchymal stromal cell that supports vascular growth.
    Authors: To C, Farnsworth R, Vail M, Chheang C, Gargett C, Murone C, Llerena C, Major A, Scott A, Janes P, Lackmann M
    PLoS ONE, 2014;9(11):e112106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  58. Laminin promotes vascular network formation in 3D in vitro collagen scaffolds by regulating VEGF uptake.
    Authors: Stamati K, Priestley J, Mudera V, Cheema U
    Exp Cell Res, 2014;327(1):68-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  59. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
    Authors: Orlova, Valeria, Drabsch, Yvette, Freund, Christia, Petrus-Reurer, Sandra, van den Hil, Francijn, Muenthaisong, Suchitra, Dijke, Peter Te, Mummery, Christin
    Arterioscler Thromb Vasc Biol, 2014;34(1):177-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  60. Migratory activity of circulating mononuclear cells is associated with cardiovascular mortality in type 2 diabetic patients with critical limb ischemia.
    Authors: Spinetti G, Specchia C, Fortunato O, Sangalli E, Clerici G, Caminiti M, Airoldi F, Losa S, Emanueli C, Faglia E, Madeddu P
    Diabetes Care, 2014;37(5):1410-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  61. Diabetes impairs stem cell and proangiogenic cell mobilization in humans.
    Authors: Fadini G, Albiero M, Vigili de Kreutzenberg S, Boscaro E, Cappellari R, Marescotti M, Poncina N, Agostini C, Avogaro A
    Diabetes Care, 2013;36(4):943-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  62. Functional and molecular characterization of ex vivo cultured epiretinal membrane cells from human proliferative diabetic retinopathy.
    Authors: Vereb Z, Lumi X, Andjelic S, Globocnik-Petrovic M, Urbancic M, Hawlina M, Facsko A, Petrovski G
    Biomed Res Int, 2013;2013(0):492376.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  63. Circulating endothelial progenitor cells decrease in infants with bronchopulmonary dysplasia and increase after inhaled nitric oxide.
    Authors: Qi, Yuanyuan, Jiang, Qian, Chen, Chao, Cao, Yun, Qian, Liling
    PLoS ONE, 2013;8(11):e79060.
    Species: Human
    Sample Types: Plasma
    Applications: Flow Cytometry
  64. An affordable method to obtain cultured endothelial cells from peripheral blood.
    Authors: Bueno-Beti C, Novella S, Lazaro-Franco M, Perez-Cremades D, Heras M, Sanchis J, Hermenegildo C
    J Cell Mol Med, 2013;17(11):1475-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  65. CXCR4 positive and angiogenic monocytes in myocardial infarction.
    Thromb Haemost, 2013;109(2):255-62.
    Species: Human
    Sample Types: Whole Blood
    Applications: Flow Cytometry
  66. The synergistic effect of everolimus and chloroquine on endothelial cell number reduction is paralleled by increased apoptosis and reduced autophagy occurrence.
    Authors: Grimaldi A, Balestrieri M, D'Onofrio N, Di Domenico G, Nocera C, Lamberti M, Tonini G, Zoccoli A, Santini D, Caraglia M, Pantano F
    PLoS ONE, 2013;8(11):e79658.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  67. Cultivation and characterization of cornea limbal epithelial stem cells on lens capsule in animal material-free medium.
    Authors: Albert R, Vereb Z, Csomos K, Moe M, Johnsen E, Olstad O, Nicolaissen B, Rajnavolgyi E, Fesus L, Berta A, Petrovski G
    PLoS ONE, 2012;7(10):e47187.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  68. Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.
    Authors: Pelosi E, Castelli G, Martin-Padura I, Bordoni V, Santoro S, Conigliaro A, Cerio A, De Santis Puzzonia M, Marighetti P, Biffoni M, Alonzi T, Amicone L, Alcalay M, Bertolini F, Testa U, Tripodi M
    PLoS ONE, 2012;7(12):e51109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  69. GMP-compliant isolation and large-scale expansion of bone marrow-derived MSC.
    Authors: Fekete N, Rojewski M, Furst D, Kreja L, Ignatius A, Dausend J, Schrezenmeier H
    PLoS ONE, 2012;7(8):e43255.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  70. Successful In Vitro Expansion and Differentiation of Cord Blood Derived CD34+ Cells into Early Endothelial Progenitor Cells Reveals Highly Differential Gene Expression.
    Authors: Ahrens I, Domeij H, Topcic D
    PLoS ONE, 2011;6(8):e23210.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  71. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells.
    Authors: Ball SG, Bayley C, Shuttleworth CA, Kielty CM
    Biochem. J., 2010;427(1):29-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  72. Distraction osteogenesis induces endothelial progenitor cell mobilization without inflammatory response in man.
    Authors: Lee DY, Cho TJ, Lee HR, Park MS, Yoo WJ, Chung CY, Choi IH
    Bone, 2010;46(3):673-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  73. Multiple receptor tyrosine kinases regulate HIF-1alpha and HIF-2alpha in normoxia and hypoxia in neuroblastoma: implications for antiangiogenic mechanisms of multikinase inhibitors.
    Authors: Nilsson MB, Zage PE, Zeng L, Xu L, Cascone T, Wu HK, Saigal B, Zweidler-McKay PA, Heymach JV
    Oncogene, 2010;29(20):2938-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  74. Comparison of endothelial progenitor cell function in type 2 diabetes with good and poor glycemic control.
    Authors: Churdchomjan, Worachat, Kheolamai, Pakpoom, Manochantr, Sirikul, Tapanadechopone, Pirath, Tantrawatpan, Chairat, U-Pratya, Yaowalak, Issaragrisil, Surapol
    BMC Endocr Disord, 2010;10(0):5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  75. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.
    Authors: Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G
    Blood, 2010;116(16):3099-107.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  76. VEGFR2 is selectively expressed by FOXP3high CD4+ Treg.
    Authors: Suzuki H, Onishi H, Wada J, Yamasaki A, Tanaka H, Nakano K, Morisaki T, Katano M
    Eur. J. Immunol., 2010;40(1):197-203.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  77. Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
    Authors: Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U
    Br. J. Haematol., 2009;145(3):399-411.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  78. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
    Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
    Exp. Hematol., 2008;36(5):545-558.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  79. Highly efficient and feeder-free production of subculturable vascular endothelial cells from primate embryonic stem cells.
    Authors: Saeki K, Yogiashi Y, Nakahara M, Nakamura N, Matsuyama S, Koyanagi A, Yagita H, Koyanagi M, Kondo Y, Yuo A
    J. Cell. Physiol., 2008;217(1):261-80.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  80. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  81. Microtubule-targeted drugs inhibit VEGF receptor-2 expression by both transcriptional and post-transcriptional mechanisms.
    Authors: Meissner M, Pinter A, Michailidou D, Hrgovic I, Kaprolat N, Stein M, Holtmeier W, Kaufmann R, Gille J
    J. Invest. Dermatol., 2008;128(8):2084-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  82. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
    Authors: Narazaki M, Segarra M, Tosato G
    Blood, 2008;111(8):4126-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  83. Endothelial progenitor cell levels in obese men with the metabolic syndrome and the effect of simvastatin monotherapy vs. simvastatin/ezetimibe combination therapy.
    Authors: Westerweel PE, Visseren FL, Hajer GR, Olijhoek JK, Hoefer IE, de Bree P, Rafii S, Doevendans PA, Verhaar MC
    Eur. Heart J., 2008;29(22):2808-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  84. Alternative splicing of vasohibin-1 generates an inhibitor of endothelial cell proliferation, migration, and capillary tube formation.
    Authors: Kern J, Bauer M, Rychli K, Wojta J, Ritsch A, Gastl G, Gunsilius E, Untergasser G
    Arterioscler. Thromb. Vasc. Biol., 2008;28(3):478-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  85. Late outgrowth endothelial progenitor cells in patients with age-related macular degeneration.
    Authors: Thill M, Strunnikova NV, Berna MJ, Gordiyenko N, Schmid K, Cousins SW, Thompson DJ, Csaky KG
    Invest. Ophthalmol. Vis. Sci., 2008;49(6):2696-708.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  86. VEGFR2 expressing circulating (progenitor) cell populations in volunteers and cancer patients.
    Authors: Vroling L, Yuana Y, Schuurhuis GJ, van Hinsbergh VW, Gundy C, de Haas R, van Cruijsen H, Boven E, Hoekman K, Broxterman HJ
    Thromb. Haemost., 2007;98(2):440-50.
    Species: Human
    Sample Types: Whole Blood
    Applications: Flow Cytometry
  87. Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus.
    Authors: Lee PY, Li Y, Richards HB, Chan FS, Zhuang H, Narain S, Butfiloski EJ, Sobel ES, Reeves WH, Segal MS
    Arthritis Rheum., 2007;56(11):3759-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  88. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007;177(3):489-500.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  89. Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
    Authors: Shawber CJ, Funahashi Y, Francisco E, Vorontchikhina M, Kitamura Y, Stowell SA, Borisenko V, Feirt N, Podgrabinska S, Shiraishi K, Chawengsaksophak K, Rossant J, Accili D, Skobe M, Kitajewski J
    J. Clin. Invest., 2007;117(11):3369-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  90. Increased circulating endothelial progenitor cells in septic patients: correlation with survival.
    Authors: Rafat N, Hanusch C, Brinkkoetter PT, Schulte J, Brade J, Zijlstra JG, van der Woude FJ, van Ackern K, Yard BA, Beck GCh
    Crit. Care Med., 2007;35(7):1677-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  91. Blood-based biomarkers of SU11248 activity and clinical outcome in patients with metastatic imatinib-resistant gastrointestinal stromal tumor.
    Authors: Norden-Zfoni A, Desai J, Manola J, Beaudry P, Force J, Maki R, Folkman J, Bello C, Baum C, DePrimo SE, Shalinsky DR, Demetri GD, Heymach JV
    Clin. Cancer Res., 2007;13(9):2643-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  92. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
    Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
    Blood, 2007;111(4):1933-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  93. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
    Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
    Br. J. Haematol., 2006;135(5):703-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  94. Enalapril increases ischemia-induced endothelial progenitor cell mobilization through manipulation of the CD26 system.
    Authors: Wang CH, Verma S, Hsieh IC, Chen YJ, Kuo LT, Yang NI, Wang SY, Wu MY, Hsu CM, Cheng CW, Cherng WJ
    J. Mol. Cell. Cardiol., 2006;41(1):34-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  95. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
    Authors: Narazaki M, Tosato G
    Blood, 2006;107(10):3892-901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  96. Expansion of human SCID-repopulating cells under hypoxic conditions.
    Authors: Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC
    J. Clin. Invest., 2003;112(1):126-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  97. Structural and functional studies of the endothelial activation antigen endothelial leucocyte adhesion molecule-1 using a panel of monoclonal antibodies.
    Authors: Pigott R, Needham LA, Edwards RM
    J. Immunol., 1991;147(1):130-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry

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