IRF4 Antibody - BSA Free

Novus Biologicals | Catalog # NBP1-76574

Novus Biologicals
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all IRF4 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human IRF4. The immunogen is located within the last 50 amino acids of IRF4.

Specificity

IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for IRF4 Antibody - BSA Free

Western Blot: IRF4 AntibodyBSA Free [NBP1-76574]

Western Blot: IRF4 AntibodyBSA Free [NBP1-76574]

Western Blot: IRF4 Antibody [NBP1-76574] - Analysis in Ramos cell lysate with antibody at 0.5 ug/mL.
Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574]

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574]

Immunocytochemistry/Immunofluorescence: IRF4 Antibody [NBP1-76574] - Jurkat cells with IRF4 antibody at 10 ug/mL.
IRF4 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574] -

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574] - Immunofluorescence of IRF4 in Jurkat cells with IRF4 antibody at 20 ug/mL.

Applications for IRF4 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/ml

Western Blot

0.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: IRF4

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.

Long Name

Interferon Regulatory Factor 4

Alternate Names

LSIRF, MUM1, NF-EM5

Gene Symbol

IRF4

UniProt

NP_002451 (Human)

Additional IRF4 Products

Product Documents for IRF4 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for IRF4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for IRF4 Antibody - BSA Free

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Protocols

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