Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Human

Applications

Validated:

Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all IRF4 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human IRF4. The immunogen is located within the last 50 amino acids of IRF4. Amino Acid Squence: NPEDYHRSIRHSSIQE

Specificity

IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Novus Biologicals Rabbit IRF4 Antibody - BSA Free (NBP1-76574) is a polyclonal antibody validated for use in WB, ELISA and ICC/IF. Anti-IRF4 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.

Scientific Data Images for IRF4 Antibody - BSA Free

Western Blot: IRF4 AntibodyBSA Free [NBP1-76574]

Western Blot: IRF4 AntibodyBSA Free [NBP1-76574]

Western Blot: IRF4 Antibody [NBP1-76574] - Analysis in Ramos cell lysate with antibody at 0.5 ug/mL.
Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574]

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574]

Immunocytochemistry/Immunofluorescence: IRF4 Antibody [NBP1-76574] - Jurkat cells with IRF4 antibody at 10 ug/mL.
IRF4 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574] -

Immunocytochemistry/ Immunofluorescence: IRF4 Antibody - BSA Free [NBP1-76574] - Immunofluorescence of IRF4 in Jurkat cells with IRF4 antibody at 20 ug/mL.

Applications for IRF4 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

10-20 ug/ml

Western Blot

0.5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: IRF4

Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.

Long Name

Interferon Regulatory Factor 4

Alternate Names

LSIRF, MUM1, NF-EM5

Gene Symbol

IRF4

UniProt

NP_002451 (Human)

Additional IRF4 Products

Product Documents for IRF4 Antibody - BSA Free

Certificate of Analysis

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Product Specific Notices for IRF4 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations for IRF4 Antibody - BSA Free

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Protocols

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FAQs

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