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Ivachtin

Catalog #: 2636 Datasheet / COA / SDS

Discontinued Product

2636 has been discontinued.
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Ivachtin | CAS No. 745046-84-8 | Caspase Inhibitors
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Description: Potent caspase-3 inhibitor

Chemical Name: 2-[4-Methyl-8-(morpholin-4-ylsulfonyl)-1,3-dioxo-1,3-dihydro-2H-pyrrolo[3,4-c]quinolin-2-yl]ethyl acetate

Purity: ≥99%

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Biological Activity

Potent, reversible inhibitor of caspase-3 (IC50 = 23 nM) that displays moderate selectivity over other caspases. Exhibits antiapoptotic activity in human Jurkat T cells treated with staurosporine; exhibits a higher level of protection than Z-VAD-FMK (Cat. No. 2163).

Technical Data

M.Wt:
447.46
Formula:
C20H21N3O7S
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
745046-84-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with the permission of ChemDiv, Inc.

Product Datasheets

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