MDNI-caged-L-glutamate

  
Catalog Number:5785
Alternate Names:caged MDNI glutamate, DNI glutamate, DNI-GLU
Chemical Name:(S)-α-Amino-2,3-dihydro-4-methoxy-5,7-dinitro-δ-oxo-1H-indole-1-pentanoic acid
Product Details
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Biological Activity
Rapidly and efficiently releases glutamate (Cat. No. 0218) when photolysed (350 - 365 nm excitation). Water soluble and stable at neutral pH, and pharmacologically inactive at neuronal glutamate receptors (up to 200 μM). 5.5 times more photosensitive than MNI-caged L-glutamate (Cat. No. 1490). Laser activation of MDNI-glu evokes a rapid increase in intracellular Ca2+ concentration in astrocytes.
Technical Data
  • M.Wt:
    368.3
  • Formula:
    C14H16N4O8
  • Solubility:
    Soluble to 10 mM in water with gentle warming and to 50 mM in DMSO
  • Purity:
    >98%
  • Storage:
    Store at -20°C
  • CAS No:
    864085-92-7
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.

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