Mouse CCL8/MCP-2 Antibody

Catalog #: MAB790
3 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
MAB790-SP
MAB790-500
MAB790-100

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Product Details

Citations (3)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse CCL8/MCP-2 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse CCL8/MCP-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant cotton rat CCL3, 4, 5, recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, recombinant mouse CCL1, 3, 4, 5, 6, 7, 9/10MIP-1 gamma, 11, 12, 17, 19, 20, 21, 22, 24, 25, 27, or recombinant rat CCL20 is observed.

Source

Monoclonal Rat IgG_2A Clone # 146123

Purification

Protein A or G purified from hybridoma culture supernatant

Immunogen

E. coli-derived recombinant mouse CCL8/MCP-2
Glu20-Pro97
Accession # Q9Z121

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Mouse CCL8/MCP‑2

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: CCL8/MCP-2

CCL8, also known as Monocyte Chemoattractant Protein 2 (MCP-2), is an inflammatory CC chemokine that attracts monocytes, eosinophils and basophils. It is produced by many cell types and signals through interactions with CCR1, CCR2, CCR3 and CCR5.

Entrez Gene IDs

6355 (Human); 20307 (Mouse)

Alternate Names

C-C motif chemokine 8; CCL8; chemokine (C-C motif) ligand 8; HC14; MCP2; MCP-2; member 8 (monocyte chemotactic protein 2); monocyte chemoattractant protein 2; SCYA10; small-inducible cytokine A8

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Mouse CCL8/MCP-2 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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Endothelial cell-derived Apelin inhibits tumor growth by altering immune cell localization
Authors: L Hu, Y Hayashi, H Kidoya, N Takakura
Scientific Reports, 2021;11(1):14047.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
Allergic airway inflammation decreases lung bacterial burden following acute Klebsiella pneumoniae infection in a neutrophil- and CCL8-dependent manner.
Authors: Dulek D, Newcomb D, Goleniewska K, Cephus J, Zhou W, Reiss S, Toki S, Ye F, Zaynagetdinov R, Sherrill T, Blackwell T, Moore M, Boyd K, Kolls J, Peebles R
Infect Immun, 2014;82(9):3723-39.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization
New asthma biomarkers: lessons from murine models of acute and chronic asthma.
Authors: Di Valentin E, Crahay C, Garbacki N, Hennuy B, Gueders M, Noel A, Foidart JM, Grooten J, Colige A, Piette J, Cataldo D
Am. J. Physiol. Lung Cell Mol. Physiol., 2009;296(2):L185-97.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P