Mouse Glut2 APC-conjugated Antibody Summary
Accession # P14246
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Glut2 in beta TC‑6 Mouse Cell Line by Flow Cytometry. beta TC-6 mouse beta cell insulinoma cell line was stained with Rat Anti-Mouse Glut2 APC-conjugated Monoclonal Antibody (Catalog # FAB1440A, filled histogram) or isotype control antibody (Catalog # IC013A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
Glut2, also known as SLC2A2, belongs to the facilitative glucose transporter protein family that comprises 13 members. It is an integral membrane glycoprotein with 12 transmembrane domains. Glut2 is expressed predominantly in liver, intestine, kidney and pancreatic beta-cells. It is a low-affinity glucose transporter that has been suggested to function as a glucose sensor in pancreatic beta-cells, and facilitate either glucose uptake or efflux from cells depending on the nutritional state (1, 2).
Poitout, V. et al. (1995) Diabetes 44:306.
- Olson, A.L. and J.E. Pessin (1996) Annu. Rev. Nut. 16:235.
Citations for Mouse Glut2 APC-conjugated Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Metastatic pancreatic neuroendocrine tumors manifest elevated T cell infiltration
Authors: J Greenberg, J Limberg, A Verma, D Kim, X Chen, YJ Lee, MD Moore, TM Ullmann, JW Thiesmeyer, Z Loewenstei, KJ Chen, CE Egan, D Stefanova, R Bareja, R Zarnegar, BM Finnerty, T Scognamigl, YN Du, O Elemento, TJ Fahey Iii, IM Min
JCI Insight, 2022;0(0):.
Sample Types: Whole Cells
Transgenic Overexpression of Galectin-3 in Pancreatic beta Cells Attenuates Hyperglycemia in Mice: Synergistic Antidiabetic Effect With Exogenous IL-33
Authors: N Jovicic, I Petrovic, N Pejnovic, B Ljujic, M Miletic Ko, S Pavlovic, I Jeftic, A Djukic, I Srejovic, V Jakovljevi, ML Lukic
Frontiers in Pharmacology, 2021;12(0):714683.
Sample Types: Whole Cells
Applications: Flow Cytometry
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