Mouse IFN-beta ELISA Kit

Name: Mouse IFN-beta ELISA Kit
Brand: R&D Systems
SKU: 42400-1
Price: 760 USD
Availability: InStock

R&D Systems | Catalog # 42400-1

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Product Documents

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Product Specifications
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Background
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Key Product Details

Assay Length

3.25 hours

Sample Type & Volume Required Per Well

Cell Culture Supernates (100 µL), Serum (100 µL)

Sensitivity

15.5 pg/mL

Assay Range

15.6-1000 pg/mL (Cell Culture Supernates, Serum)

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Product Specifications

Measurement

Quantitative ELISA

Detection Method

Colorimetric - 450nm (TMB)

Conjugate

Biotin

Species

Mouse

Specificity

Mouse IFN-beta

Cross-reactivity

< 0.5% cross-reactivity observed with available related molecules. < 50% cross-species reactivity observed with species tested.

Interference

No significant interference observed with available related molecules.

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-beta

IFN-beta (Interferon-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.