Mouse IFN-beta ELISA Kit

Newer Version Available: MIFNB0
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Product Details
Citations (30)
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Mouse IFN-beta ELISA Kit Summary

Assay Length
3.25 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (100 uL), Serum (100 uL)
15.5 pg/mL
Assay Range
15.6 - 1,000 pg/mL (Cell Culture Supernates, Serum)
Mouse IFN-beta
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
No significant interference observed with available related molecules.

Product Summary

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Preparation and Storage

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-beta

Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.

Long Name:
Interferon beta
Entrez Gene IDs:
3456 (Human); 15977 (Mouse); 24481 (Rat)
Alternate Names:
Fibroblast interferon; IFB; IFBIFNB; IFF; IFNB; IFNB1; IFNbeta; IFN-beta; interferon beta; interferon, beta 1, fibroblast; MGC96956

Citations for Mouse IFN-beta ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

30 Citations: Showing 1 - 10
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  1. The Ability of Postimmunobiotics from L. rhamnosus CRL1505 to Protect against Respiratory Syncytial Virus and Pneumococcal Super-Infection Is a Strain-Dependent Characteristic
    Authors: F Raya Tonet, P Clua, K Fukuyama, G Marcial, J Sacur, G Marranzino, M Tomokiyo, G Vizoso-Pin, A Garcia-Can, S Kurata, H Kitazawa, J Villena
    Microorganisms, 2022-11-03;10(11):.
    Species: Mouse
    Sample Types: BALF
  2. MicroRNA-129-5p alleviates spinal cord injury in mice via suppressing the apoptosis and inflammatory response through HMGB1/TLR4/NF-&kappaB pathway
    Authors: G Wan, Y An, J Tao, Y Wang, Q Zhou, R Yang, Q Liang
    Biosci. Rep., 2020-03-27;40(3):.
    Species: Mouse
    Sample Types: Serum
  3. Small Heterodimer Partner Controls the Virus-Mediated Antiviral Immune Response by Targeting CREB-Binding Protein in the Nucleus
    Authors: JH Kim, JE Yoon, C Nikapitiya, TH Kim, MB Uddin, HC Lee, YH Kim, JH Hwang, K Chathurang, WAG Chathurang, HS Choi, CJ Kim, JU Jung, CH Lee, JS Lee
    Cell Rep, 2019-05-14;27(7):2105-2118.e5.
    Species: Mouse
    Sample Types: cell culture supernatant
  4. The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses
    Authors: K Wang, H Ma, H Liu, W Ye, Z Li, L Cheng, L Zhang, Y Lei, L Shen, F Zhang
    Cell Rep, 2019-05-14;27(7):2075-2091.e5.
    Species: Human, Mouse
    Sample Types: Cell Cultue Supernates, Serum
  5. A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion
    Authors: P Xia, S Wang, B Ye, Y Du, C Li, Z Xiong, Y Qu, Z Fan
    Immunity, 2018-04-03;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  6. Comparison of the Anti-Inflammatory Activities of Supercritical Carbon Dioxide versus Ethanol Extracts from Leaves of Perilla frutescens Britt. Radiation Mutant
    Authors: CH Jin, HC Park, Y So, B Nam, SN Han, JB Kim
    Molecules, 2017-02-17;22(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination
    Nat. Immunol, 2016-12-19;0(0):.
    Species: Mouse
    Sample Types: Serum
  8. Rosmarinic Acid Methyl Ester Inhibits LPS-Induced NO Production via Suppression of MyD88- Dependent and -Independent Pathways and Induction of HO-1 in RAW 264.7 Cells
    Molecules, 2016-08-18;21(8):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  9. IFN-? Production During the dsRNA Response in Hepatocytes Involves Coordinated and Feed Forward Signaling Through TLR3, PKR, iNOS and Src
    J Biol Chem, 2016-05-17;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  10. An RNA Molecule Derived From Sendai Virus DI Particles Induces Antitumor Immunity and Cancer Cell-selective Apoptosis.
    Authors: Liu L, Nishikawa T, Kaneda Y
    Mol Ther, 2015-11-09;24(1):135-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. Pattern recognition receptor-initiated innate antiviral responses in mouse epididymal epithelial cells.
    Authors: Zhu W, Zhao S, Liu Z, Cheng L, Wang Q, Yan K, Chen Q, Wu H, Han D
    J Immunol, 2015-04-03;194(10):4825-35.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  12. TRIM26 negatively regulates interferon-beta production and antiviral response through polyubiquitination and degradation of nuclear IRF3.
    Authors: Wang P, Zhao W, Zhao K, Zhang L, Gao C
    PLoS Pathog, 2015-03-12;11(3):e1004726.
    Species: Mouse
    Sample Types: Serum
  13. IRAK4 as a molecular target in the amelioration of innate immunity-related endotoxic shock and acute liver injury by chlorogenic acid.
    Authors: Park, Sun Hong, Baek, Seung-Il, Yun, Jieun, Lee, Seungmin, Yoon, Da Young, Jung, Jae-Kyun, Jung, Sang-Hun, Hwang, Bang Yeo, Hong, Jin Tae, Han, Sang-Bae, Kim, Youngsoo
    J Immunol, 2014-12-29;194(3):1122-30.
    Species: Mouse
    Sample Types: Serum
  14. NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection.
    Authors: Ranjan P, Singh N, Kumar A, Neerincx A, Kremmer E, Cao W, Davis W, Katz J, Gangappa S, Lin R, Kufer T, Sambhara S
    Eur J Immunol, 2014-12-23;45(3):758-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. Structural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells.
    Authors: Zaru R, Edgar A, Hanauer A, Watts C
    Mol Cell Biol, 2014-10-20;35(1):132-40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  16. Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction.
    Authors: Desch, A Nicole, Gibbings, Sophie L, Clambey, Eric T, Janssen, William, Slansky, Jill E, Kedl, Ross M, Henson, Peter M, Jakubzick, Claudia
    Nat Commun, 2014-08-19;5(0):4674.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  17. TIR-domain-containing adapter-inducing interferon-beta (TRIF) regulates Th17-mediated intestinal immunopathology in colitis.
    Authors: Kanagavelu S, Flores C, Termini J, Riveron R, Romero L, Chung K, Ruiz J, Hyun J, Yuan X, Dagvadorj J, Fukata M
    Mucosal Immunol, 2014-07-30;8(2):296-306.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  18. STAT4 deficiency fails to induce lung Th2 or Th17 immunity following primary or secondary respiratory syncytial virus (RSV) challenge but enhances the lung RSV-specific CD8+ T cell immune response to secondary challenge.
    Authors: Dulek D, Newcomb D, Toki S, Goliniewska K, Cephus J, Reiss S, Bates J, Crowe J, Boyd K, Moore M, Zhou W, Peebles R
    J Virol, 2014-06-11;88(17):9655-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  19. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27.
    Authors: Bosmann M, Strobl B, Kichler N, Rigler D, Grailer J, Pache F, Murray P, Muller M, Ward P
    J Leukoc Biol, 2014-03-06;96(1):123-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. PIKfyve, a class III lipid kinase, is required for TLR-induced type I IFN production via modulation of ATF3.
    Authors: Cai, Xinming, Xu, Yongyao, Kim, You-Me, Loureiro, Joseph, Huang, Qian
    J Immunol, 2014-03-05;192(7):3383-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. IL-15 complexes induce NK- and T-cell responses independent of type I IFN signaling during rhinovirus infection.
    Authors: Jayaraman A, Jackson D, Message S, Pearson R, Aniscenko J, Caramori G, Mallia P, Papi A, Shamji B, Edwards M, Westwick J, Hansel T, Stanciu L, Johnston S, Bartlett N
    Mucosal Immunol, 2014-01-29;7(5):1151-64.
    Species: Mouse
    Sample Types: Whole Cells
  22. DNA-dependent activator of interferon-regulatory factors (DAI) promotes lupus nephritis by activating the calcium pathway.
    Authors: Zhang W, Zhou Q, Xu W, Cai Y, Yin Z, Gao X, Xiong S
    J Biol Chem, 2013-04-03;288(19):13534-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. DNA-PK is a DNA sensor for IRF-3-dependent innate immunity.
    Authors: Ferguson, Brian J, Mansur, Daniel S, Peters, Nicholas, Ren, Hongwei, Smith, Geoffrey
    Elife, 2012-12-18;1(0):e00047.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
    Authors: Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, Yang C, Hsing E, Chen L, Shih S, Shiau A, Lei H, Tan T, Ling P
    J Biol Chem, 2012-07-25;287(38):32216-21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2010-11-22;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  26. Selective induction of host genes by MVA-B, a candidate vaccine against HIV/AIDS.
    Authors: Guerra S, Gonzalez JM, Climent N, Reyburn H, Lopez-Fernandez LA, Najera JL, Gomez CE, Garcia F, Gatell JM, Gallart T, Esteban M
    J. Virol., 2010-06-09;84(16):8141-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  27. NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
    Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
    J. Clin. Invest., 2010-04-12;120(5):1645-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Basal expression levels of IFNAR and Jak-STAT components are determinants of cell-type-specific differences in cardiac antiviral responses.
    Authors: Zurney J, Howard KE, Sherry B
    J. Virol., 2007-10-17;81(24):13668-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.
    Authors: Zetterstrom CK, Jiang W, Wahamaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H
    J. Leukoc. Biol., 2007-10-03;83(1):31-8.
    Species: Mouse
    Sample Types: Whole Cells
  30. Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo.
    Authors: Qin L, Greenland JR, Moriya C
    J. Virol., 2007-07-25;81(19):10606-13.
    Species: Mouse
    Sample Types: Tissue Homogenates


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