Mouse IgG1 Isotype Control Summary
rmMCP-5, rvMCV type 2, rhMDC, rmMDC, rhMIG, rmMIG, rhMIP-1 alpha, rmMIP-1 alpha, rmMIP-1 beta, rhMIP-1δ, rmMIP-1 gamma, rmMIP-2, rhMIP-3 alpha,
rmMIP-3 alpha, rrMIP-3 alpha, rhMIP-3 beta, rmMIP-3 beta, rvMIP-I, rvMIP-II, rvMIP-III, rhMPIF-1, rhNAP-2, rhPARC, rhRANTES, rmRANTES, rhSDF-1 alpha, rmSDF-1 alpha, rhSDF-1 beta, rhTARC, rmTARC, rmTCA-3, rhTeck, or rmTeck.
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Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data

Detection of Mouse IgG1Isotype Control by Flow Cytometry Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human LILRA6/CD85b Monoclonal Antibody (Catalog # MAB8656, filled histogram) or Mouse IgG1Isotype Control Antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IgG1
R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.
Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.
Product Datasheets
Citations for Mouse IgG1 Isotype Control
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
231
Citations: Showing 1 - 10
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The Anti-Vascular Endothelial Growth Factor Receptor 1 (VEGFR-1) D16F7 Monoclonal Antibody Inhibits Melanoma Adhesion to Soluble VEGFR-1 and Tissue Invasion in Response to Placenta Growth Factor
Authors: MG Atzori, C Ceci, F Ruffini, M Scimeca, R Cicconi, M Mattei, PM Lacal, G Graziani
Cancers, 2022;14(22):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Tumor cell-derived ANGPTL2 promotes beta-catenin-driven intestinal tumorigenesis
Authors: H Horiguchi, T Kadomatsu, S Yumoto, T Masuda, K Miyata, S Yamamura, M Sato, J Morinaga, S Ohtsuki, H Baba, T Moroishi, Y Oike
Oncogene, 2022;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Isotype Control -
Up-regulation of ST18 in pemphigus vulgaris drives a self-amplifying p53-dependent pathomechanism resulting in decreased desmoglein 3 expression
Authors: S Assaf, D Vodo, K Malovitski, J Mohamad, S Bergson, Y Feller, L Malki, O Sarig, E Sprecher
Scientific Reports, 2022;12(1):5958.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1beta to downregulate PPARalpha and FOXO3
Authors: Y Li, Y Zhu, S Feng, Y Ishida, TP Chiu, T Saito, S Wang, DK Ann, JJ Ou
Cell Reports, 2022;38(4):110284.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
Authors: M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda
Nature Communications, 2022;13(1):166.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
TNF-alpha Affects Signature Cytokines of Th1 and Th17 T Cell Subsets through Differential Actions on TNFR1 and TNFR2
Authors: B Pesce, CH Ribeiro, M Larrondo, V Ramos, L Soto, D Catalán, JC Aguillón
International Journal of Molecular Sciences, 2022;23(16):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Chemokine Receptor Expression on T Cells Is Modulated by CAFs and Chemokines Affect the Spatial Distribution of T Cells in Pancreatic Tumors
Authors: L Gorchs, M Oosthoek, T Yucel-Lind, CF Moro, H Kaipe
Cancers, 2022;14(15):.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Quercetin Reduces the Development of 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Induced Cleft Palate in Mice by Suppressing CYP1A1 via the Aryl Hydrocarbon Receptor
Authors: K Satake, T Ishii, T Morikawa, T Sakamoto, Y Nishii
Nutrients, 2022;14(12):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Isotype Control -
Cardiac fibroblasts regulate the development of heart failure via Htra3-TGF-beta-IGFBP7 axis
Authors: T Ko, S Nomura, S Yamada, K Fujita, T Fujita, M Satoh, C Oka, M Katoh, M Ito, M Katagiri, T Sassa, B Zhang, S Hatsuse, T Yamada, M Harada, H Toko, E Amiya, M Hatano, O Kinoshita, K Nawata, H Abe, T Ushiku, M Ono, M Ikeuchi, H Morita, H Aburatani, I Komuro
Nature Communications, 2022;13(1):3275.
Species: Mouse
Sample Types: In Vivo
Applications: In vivo Control -
Serum bridging molecules drive candidal invasion of human but not mouse endothelial cells
Authors: QT Phan, NV Solis, J Lin, M Swidergall, S Singh, H Liu, DC Sheppard, AS Ibrahim, AP Mitchell, SG Filler
PloS Pathogens, 2022;18(7):e1010681.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Sarcoma Common MHC-I Haplotype Restricts Tumor-Specific CD8+ T Cell Response
Authors: L Mosca, A de Angelis, A Ronchi, A De Chiara, F Fazioli, C Ruosi, L Altucci, M Conte, F de Nigris
Cancers, 2022;14(14):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Inflammation triggers ILC3 patrolling of the intestinal barrier
Authors: A Jarade, Z Garcia, S Marie, A Demera, I Prinz, P Bousso, JP Di Santo, N Serafini
Nature Immunology, 2022;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19
Authors: S Mairpady S, A Gómez-Meji, TA Schweizer, M Huemer, CC Chang, C Acevedo, J Bergada-Pi, C Vulin, DA Hofmaenner, TC Scheier, S Hertegonne, E Parietti, N Miroshniko, PD Wendel Gar, MP Hilty, PK Buehler, RA Schuepbach, SD Brugger, AS Zinkernage
PloS Pathogens, 2022;18(1):e1010176.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Tumor-infiltrated activated B cells suppress liver metastasis of colorectal cancers
Authors: Y Xu, Z Wei, M Feng, D Zhu, S Mei, Z Wu, Q Feng, W Chang, M Ji, C Liu, Y Zhu, L Shen, F Yang, Y Chen, Y Feng, J Xu, D Zhu
Cell Reports, 2022;40(9):111295.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells
Authors: M Llorián-Sa, EM Byrne, M Szczepan, K Little, M Chen, H Xu
Journal of Neuroinflammation, 2022;19(1):182.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Bovine neutrophil chemotaxis to Listeria monocytogenes in neurolisteriosis depends on microglia-released rather than bacterial factors
Authors: S Bagatella, N Haghayegh, C Monney, M Polidori, FM Gall, E Marchionat, F Serra, R Riedl, B Engelhardt, A Oevermann
Journal of Neuroinflammation, 2022;19(1):304.
Species: Bovine
Sample Types: Cell Culture Supernates
Applications: Isotype Control -
Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for beta cell replacement
Authors: R Chimienti, T Baccega, S Torchio, F Manenti, S Pellegrini, A Cospito, A Amabile, MT Lombardo, P Monti, V Sordi, A Lombardo, M Malnati, L Piemonti
Cell Reports, 2022;40(13):111423.
Species: Mouse
Sample Types: In Vivo
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Proteomic Landscape and Deduced Functions of the Cardiac 14-3-3 Protein Interactome
Authors: JH Qu, KV Tarasov, K Chakir, YS Tarasova, DR Riordon, EG Lakatta
Cells, 2022;11(21):.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Isotype Control -
Dry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing
Authors: Y Matsuno, M Yanagihara, K Ueno, T Saito, H Kurazumi, R Suzuki, S Katsura, A Oga, K Hamano
Scientific Reports, 2022;12(1):12519.
Species: Mouse
Sample Types: Whole Tissue
Applications: Neutralization Control -
Neutralizing mAbs against SFTS Virus Gn Protein Show Strong Therapeutic Effects in an SFTS Animal Model
Authors: M Shimojima, S Sugimoto, K Umekita, T Onodera, K Sano, H Tani, Y Takamatsu, T Yoshikawa, T Kurosu, T Suzuki, Y Takahashi, H Ebihara, M Saijo
Viruses, 2022;14(8):.
Species: Primate - C. aethiops
Sample Types: Whole Cells
Applications: Isotype Control -
Inflammatory activation of surface molecule shedding by upregulation of the pseudoprotease iRhom2 in colon epithelial cells
Authors: AA Giese, A Babendreye, P Krappen, A Gross, P Strnad, S Düsterhöft, A Ludwig
Scientific Reports, 2021;11(1):24230.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201
Authors: I Trenevska, AP Anderson, C Bentley, T Hassanali, S Wiblin, S Maguire, F Pezzella, AH Banham, D Li
PLoS ONE, 2021;16(4):e0249967.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
IL-10 and class 1 histone deacetylases act synergistically and independently on the secretion of proinflammatory mediators in alveolar macrophages
Authors: BA Stanfield, T Purves, S Palmer, B Sullenger, K Welty-Wolf, K Haines, S Agarwal, G Kasotakis
PLoS ONE, 2021;16(1):e0245169.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
The ammonia oxidizing bacterium Nitrosomonas eutropha blocks T helper 2 cell polarization via the anti-inflammatory cytokine IL-10
Authors: D Maura, N Elmekki, CA Goddard
Scientific Reports, 2021;11(1):14162.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
Authors: N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain
Redox Biology, 2021;46(0):102092.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
Aberrant Expression of and Cell Death Induction by Engagement of the MHC-II Chaperone CD74 in Anaplastic Large Cell Lymphoma (ALCL)
Authors: KD Wurster, M Costanza, S Kreher, S Glaser, B Lamprecht, N Schleussne, I Anagnostop, M Hummel, K Jöhrens, H Stein, A Molina, A Diepstra, B Gillissen, K Köchert, R Siebert, O Merkel, L Kenner, M Janz, S Mathas
Cancers, 2021;13(19):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Perlecan in the Natural and Cell Therapy Repair of Human Adult Articular Cartilage: Can Modifications in This Proteoglycan Be a Novel Therapeutic Approach?
Authors: J Garcia, HS McCarthy, JH Kuiper, J Melrose, S Roberts
Biomolecules, 2021;11(1):.
Species: Human
Sample Types: Whole Tissue
Applications: Isotype Control -
Evidence for osteocyte-mediated bone-matrix degradation associated with periprosthetic joint infection (PJI)
Authors: RT Ormsby, AR Zelmer, D Yang, NJ Gunn, Y Starczak, SP Kidd, R Nelson, LB Solomon, GJ Atkins
European cells & materials, 2021;41(0):264-280.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
ALDH1 expression predicts progression of premalignant lesions to cancer in Type I endometrial carcinomas
Authors: V Mah, Y Elshimali, A Chu, NA Moatamed, JP Uzzell, J Tsui, S Schettler, H Shakeri, M Wadehra
Scientific Reports, 2021;11(1):11949.
Species: Human
Sample Types: Whole Tissue
Applications: IHC Control -
The Globular C1q Receptor Is Required for Epidermal Growth Factor Receptor Signaling during Candida albicans Infection
Authors: QT Phan, J Lin, NV Solis, M Eng, M Swidergall, F Wang, S Li, SL Gaffen, TF Chou, SG Filler
MBio, 2021;0(0):e0271621.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Epithelial membrane protein 2 (Emp2) modulates innate immune cell population recruitment at the maternal-fetal interface
Authors: A Chu, SY Kok, J Tsui, MC Lin, B Aguirre, M Wadehra
Journal of reproductive immunology, 2021;145(0):103309.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Pathophysiological clinical features of an infant with hypertension secondary to multicystic dysplastic kidney: a case report
Authors: K Sugimoto, T Enya, K Joh, K Miyazaki, T Miyazawa, R Ohshima, S Marutani, T Tsukasa, M Okada
Bmc Nephrology, 2021;22(1):55.
Species: Human
Sample Types: Whole Tissue
Applications: Isotype Control -
Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses
Authors: W Chen, SS Foo, E Hong, C Wu, WS Lee, SA Lee, D Evseenko, MEL Moreira, A García-Sas, G Cheng, K Nielsen-Sa, P Brasil, E Avvad-Port, JU Jung
Nature Microbiology, 2021;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Intercellular coupling between peripheral circadian oscillators by TGF-beta signaling
Authors: AM Finger, S Jäschke, M Del Olmo, R Hurwitz, AE Granada, H Herzel, A Kramer
Science Advances, 2021;7(30):.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization Control -
TNFalpha Mediates Inflammation-Induced Effects on PPARG Splicing in Adipose Tissue and Mesenchymal Precursor Cells
Authors: S Cataldi, M Aprile, D Melillo, I Mucel, S Giorgetti-, M Cormont, P Italiani, M Blüher, JF Tanti, A Ciccodicol, V Costa
Cells, 2021;11(1):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Recombinant CCL17-dependent CCR4 activation alleviates neuroinflammation and neuronal apoptosis through the PI3K/AKT/Foxo1 signaling pathway after ICH in mice
Authors: S Deng, P Jin, P Sherchan, S Liu, Y Cui, L Huang, JH Zhang, Y Gong, J Tang
Journal of Neuroinflammation, 2021;18(1):62.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization Control -
Plasma cell dynamics in the bone marrow niche
Authors: Z Benet, Z Jing, DR Fooksman
Cell Reports, 2021;34(6):108733.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
P-selectin axis plays a key role in microglia immunophenotype and glioblastoma progression
Authors: E Yeini, P Ofek, S Pozzi, N Albeck, D Ben-Shusha, G Tiram, S Golan, R Kleiner, R Sheinin, S Israeli Da, S Reich-Zeli, R Grossman, Z Ram, H Brem, TM Hyde, P Magod, D Friedmann-, A Madi, R Satchi-Fai
Nature Communications, 2021;12(1):1912.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
High Glucose Exacerbates TNF-&alpha-Induced Proliferative Inhibition in Human Periodontal Ligament Stem Cells through Upregulation and Activation of TNF Receptor 1
Authors: W Zhu, Q Qiu, H Luo, F Zhang, J Wu, X Zhu, M Liang
Stem Cells Int, 2020;2020(0):4910767.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Autophagy-based unconventional secretion of HMGB1 by keratinocytes plays a pivotal role in psoriatic skin in?ammation
Authors: Z Wang, H Zhou, H Zheng, X Zhou, G Shen, X Teng, X Liu, J Zhang, X Wei, Z Hu, F Zeng, Y Hu, J Hu, X Wang, S Chen, J Cheng, C Zhang, Y Gui, S Zou, Y Hao, Q Zhao, W Wu, Y Zhou, K Cui, N Huang, Y Wei, W Li, J Li
Autophagy, 2020;0(0):1-24.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer
Authors: R Nicolle, Y Blum, P Duconseil, C Vanbrugghe, N Brandone, F Poizat, J Roques, M Bigonnet, O Gayet, M Rubis, N Elarouci, L Armenoult, M Ayadi, A de Reyniès, M Giovannini, P Grandval, S Garcia, C Canivet, J Cros, B Bournet, L Buscail,, V Moutardier, M Gilabert, J Iovanna, N Dusetti
EBioMedicine, 2020;57(0):102858.
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Differentiation of induced pluripotent stem cells into definitive endoderm on Activin A-functionalized gradient surfaces
Authors: L Andreasson, H Evenbratt, R Mobini, S Simonsson
J Biotechnol, 2020;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Androgens predispose males to monocyte-mediated immunopathology by inducing the expression of leukocyte recruitment factor CXCL1
Authors: J Sellau, M Groneberg, H Fehling, T Thye, S Hoenow, C Marggraff, M Weskamm, C Hansen, S Stanelle-B, S Kuehl, J Noll, V Wolf, NG Metwally, SH Hagen, C Dorn, J Wernecke, H Ittrich, E Tannich, T Jacobs, I Bruchhaus, M Altfeld, H Lotter
Nat Commun, 2020;11(1):3459.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Development of canine PD-1/PD-L1 specific monoclonal antibodies and amplification of canine T cell function
Authors: JW Choi, SS Withers, H Chang, JA Spanier, VL De La Trin, H Panesar, BT Fife, R Sciammas, EE Sparger, PF Moore, MS Kent, RB Rebhun, SJ McSorley
PLoS ONE, 2020;15(7):e0235518.
Species: Canine
Sample Types: Whole Cell
Applications: FACS -
Single-cell analysis reveals fibroblast clusters linked to immunotherapy resistance in cancer
Authors: Y Kieffer, HR Hocine, G Gentric, F Pelon, C Bernard, B Bourachot, S Lameiras, L Albergante, C Bonneau, A Guyard, K Tarte, A Zinovyev, S Baulande, G Zalcman, A Vincent-Sa, F Mechta-Gri
Cancer Discov, 2020;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Activin A Modulates Inflammation in Acute Pancreatitis and Strongly Predicts Severe Disease Independent of Body Mass Index
Authors: AL Thomas, K Castellano, G Mancinelli, Y Xia, J Bauer, C Yazici, G Fantuzzi, RF Hwang, NL Krett, GI Papachrist, DC Whitcomb, B Jung
Clin Transl Gastroenterol, 2020;11(5):e00152.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Species-, organ- and cell-type-dependent expression of SPARCL1 in human and mouse tissues
Authors: A Klingler, D Regensburg, C Tenkerian, N Britzen-La, A Hartmann, M Stürzl, E Naschberge
PLoS ONE, 2020;15(5):e0233422.
Species: Mouse
Sample Types: Whole Tissue
Applications: Isotype Control -
Cancer-associated fibroblast heterogeneity in axillary lymph nodes drives metastases in breast cancer through complementary mechanisms
Authors: F Pelon, B Bourachot, Y Kieffer, I Magagna, F Mermet-Mei, I Bonnet, A Costa, AM Givel, Y Attieh, J Barbazan, C Bonneau, L Fuhrmann, S Descroix, D Vignjevic, P Silberzan, MC Parrini, A Vincent-Sa, F Mechta-Gri
Nat Commun, 2020;11(1):404.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody
Authors: N Bhudia, S Desai, N King, N Ancellin, D Grillot, AA Barnes, SJ Dowell
Sci Rep, 2020;10(1):1004.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Characterization of zika virus infection of human fetal cardiac mesenchymal stromal cells
Authors: F Rossi, B Josey, EC Sayitoglu, R Potens, T Sultu, AD Duru, V Beljanski
PLoS ONE, 2020;15(9):e0239238.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
A novel circulating tamiami mammarenavirus shows potential for zoonotic spillover
Authors: H Moreno, A Rastrojo, R Pryce, C Fedeli, G Zimmer, TA Bowden, G Gerold, S Kunz
PloS Neglected Tropical Diseases, 2020;14(12):e0009004.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Chemotherapy-induced IL-8 upregulates MDR1/ABCB1 in tumor blood vessels and results in unfavorable outcome
Authors: H Kikuchi, N Maishi, DA Annan, M Towfik Ala, R Ibrahim Ha, M Sato, M Morimoto, R Takeda, K Ishizuka, R Matsumoto, T Akino, K Tsuchiya, T Abe, T Osawa, N Miyajima, S Maruyama, T Harabayash, M Azuma, K Yamashiro, K Ameda, A Kashiwagi, Y Matsuno, Y Hida, N Shinohara, K Hida
Cancer Res., 2020;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Isotype Control -
CXCR4 or CXCR7 antagonists treat endometriosis by reducing bone marrow cell trafficking
Authors: N Pluchino, R Mamillapal, S Shaikh, S Habata, A Tal, M Gaye, HS Taylor
J. Cell. Mol. Med., 2020;24(4):2464-2474.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
RAC1B Regulation of TGFB1 Reveals an Unexpected Role of Autocrine TGF&beta1 in the Suppression of Cell Motility
Authors: H Ungefroren, H Otterbein, UF Wellner, T Keck, H Lehnert, JU Marquardt
Cancers, 2020;12(12):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Ex vivo culture of lesional psoriasis skin for pharmacological testing
Authors: ML Tiirikaine, A Woetmann, H Norsgaard, LF Santamaria, P Lovato
J. Dermatol. Sci., 2019;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Tissue Culture -
Fluoxetine induces direct inhibitory effects on mesenchymal stem cell?derived osteoprogenitor cells independent of serotonin concentration
Authors: SM Koura, M Salama, M El-Hussiny, MEA Khalil, A Lotfy, SA Hassan, SA Gad Elhak, MA Sobh
Mol Med Rep, 2019;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Flow Cytometry -
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice
Authors: M Kaur, AC Drake, G Hu, S Rudnick, Q Chen, R Phennicie, R Attar, J Nemeth, F Gaudet, J Chen
J. Immunol., 2019;0(0):.
Species: Human
Sample Types:
Applications: BFC Control -
Antibody opsonization enhances MAIT cell responsiveness to bacteria via a TNF dependent mechanism
Authors: Z Bánki, L Krabbendam, D Klaver, T Leng, S Kruis, H Mehta, B Müllauer, D Orth-Hölle, H Stoiber, CB Willberg, P Klenerman
Immunol. Cell Biol., 2019;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
CXCL4 assembles DNA into liquid crystalline complexes to amplify TLR9-mediated interferon-? production in systemic sclerosis
Authors: R Lande, EY Lee, R Palazzo, B Marinari, I Pietrafort, GS Santos, Y Mattenberg, F Spadaro, K Stefananto, N Iannace, AM Dufour, M Falchi, M Bianco, E Botti, L Bianchi, M Alvarez, V Riccieri, ME Truchetet, G C L Wong, C Chizzolini, L Frasca
Nat Commun, 2019;10(1):1731.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture -
Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1
Authors: H Yousef, CJ Czupalla, D Lee, MB Chen, AN Burke, KA Zera, J Zandstra, E Berber, B Lehallier, V Mathur, RV Nair, LN Bonanno, AC Yang, T Peterson, H Hadeiba, T Merkel, J Körbelin, M Schwaninge, MS Buckwalter, SR Quake, EC Butcher, T Wyss-Coray
Nat. Med., 2019;0(0):.
Species: Human
Sample Types: Plasma
Applications: Immunoprecipitation -
Pretreatment of Glioblastoma with Bortezomib Potentiates Natural Killer Cell Cytotoxicity through TRAIL/DR5 Mediated Apoptosis and Prolongs Animal Survival
Authors: A Gras Navar, H Espedal, JV Joseph, L Trachsel-M, M Bahador, B Tore Gjert, E Klæboe Kri, A Simonsen, H Miletic, P Øyvind Eng, MA Rahman, M Chekenya
Cancers (Basel), 2019;11(7):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
MUC20 expression marks the receptive phase of the human endometrium
Authors: A Stepanjuk, M Koel, M Pook, M Saare, K Jääger, M Peters, K Krjutškov, S Ingerpuu, A Salumets
Reprod. Biomed. Online, 2019;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria
Authors: S Suliman, M Murphy, M Musvosvi, A Gela, EW Meermeier, H Geldenhuys, C Hopley, A Toefy, N Bilek, A Veldsman, WA Hanekom, JL Johnson, WH Boom, G Obermoser, H Huang, M Hatherill, DM Lewinsohn, E Nemes, TJ Scriba
J. Immunol., 2019;0(0):.
Species: Human
Sample Types: Whole Blood
Applications: Neutralization -
Monoclonal Antibody to Marinobufagenin Downregulates TGFbeta Profibrotic Signaling in Left Ventricle and Kidney and Reduces Tissue Remodeling in Salt-Sensitive Hypertension
Authors: Y Zhang, W Wei, V Shilova, NN Petrashevs, VI Zernetkina, YN Grigorova, CA Marshall, RC Fenner, E Lehrmann, WH Wood, KG Becker, EG Lakatta, AY Bagrov, OV Fedorova
J Am Heart Assoc, 2019;8(20):e012138.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo -
Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis
Authors: D Izadi, TB Layton, L Williams, F McCann, M Cabrita, AI Espirito S, W Xie, M Fritzsche, H Colin-York, M Feldmann, KS Midwood, J Nanchahal
Sci Adv, 2019;5(12):eaay0370.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
α11?1 Integrin is Induced in a Subset of Cancer-Associated Fibroblasts in Desmoplastic Tumor Stroma and Mediates In Vitro Cell Migration
Authors: C Zeltz, J Alam, H Liu, PM Erusappan, H Hoschuetzk, A Molven, H Parajuli, E Cukierman, DE Costea, N Lu, D Gullberg
Cancers (Basel), 2019;11(6):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay -
The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection
Authors: L Miarka, C Hauser, O Helm, D Holdhof, S Beckinger, JH Egberts, JP Gundlach, L Lenk, S Rahn, W Mikulits, A Trauzold, S Sebens
Cancers (Basel), 2019;11(6):.
Species: Human
Sample Types: Transfected Whole Cells
Applications: Neutralization Control -
Interaction of Pregnancy-Specific Glycoprotein 1 With Integrin alpha5beta1 Is a Modulator of Extravillous Trophoblast Functions
Authors: S Rattila, CEE Dunk, M Im, O Grichenko, Y Zhou, M Yanez-Mo, SM Blois, KM Yamada, O Erez, N Gomez-Lope, SJ Lye, B Hinz, R Romero, M Cohen, G Dveksler
Cells, 2019;8(11):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging
Authors: DP Muñoz, SM Yannone, A Daemen, Y Sun, F Vakar-Lope, M Kawahara, AM Freund, F Rodier, JD Wu, PY Desprez, DH Raulet, PS Nelson, LJ van 't Vee, J Campisi, JP Coppé
JCI Insight, 2019;5(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
TGF-?1 promotes expression of fibrosis-related genes through the induction of histone variant H3.3 and histone chaperone HIRA
Authors: T Shindo, S Doi, A Nakashima, K Sasaki, K Arihiro, T Masaki
Sci Rep, 2018;8(1):14060.
Species: Mouse
Sample Types: In Vivo
Applications: Isotype Control -
CXCL5 secreted from adipose tissue-derived stem cells promotes cancer cell proliferation
Authors: Y Zhao, X Zhang, H Zhao, J Wang, Q Zhang
Oncol Lett, 2018;15(2):1403-1410.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation
Authors: YS Huang, NY Chiang, GW Chang, HH Lin
Sci Rep, 2018;8(1):4532.
Applications: Isotype Control -
A Subset of Paracrine Factors as Efficient Biomarkers for Predicting Vascular Regenerative Efficacy of Mesenchymal Stromal/Stem Cells
Authors: HK Kim, SG Lee, SW Lee, BJ Oh, JH Kim, JA Kim, G Lee, JD Jang, YA Joe
Stem Cells, 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Role of the E2 hypervariable region (HVR1) in the immunogenicity of a recombinant HCV vaccine
Authors: JLM Law, M Logan, J Wong, J Kundu, D Hockman, A Landi, C Chen, K Crawford, M Wininger, J Johnson, C Mesa Princ, E Dudek, N Mehta, DL Tyrrell, M Houghton
J. Virol., 2018;0(0):.
Species: Mouse
Sample Types: Serum
Applications: ELISA -
Cystic fibrosis epithelial cells are primed for apoptosis as a result of increased Fas (CD95)
Authors: Q Chen, SPS Pandi, L Kerrigan, NG McElvaney, CM Greene, JS Elborn, CC Taggart, S Weldon
J. Cyst. Fibros., 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival
Authors: L Kisiswa, D Fernández-, MC Sergaki, CF Ibáñez
Cell Rep, 2018;24(4):1013-1024.
Species: Mouse
Sample Types: Whole Cells
Applications: Isotype Control -
Exposure to wild-type AAV drives distinct capsid immunity profiles in humans
Authors: K Kuranda, P Jean-Alpho, C Leborgne, R Hardet, F Collaud, S Marmier, H Costa Verd, G Ronzitti, P Veron, F Mingozzi
J. Clin. Invest., 2018;0(0):.
Species: Human
Sample Types: Whole Cells
-
Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines
Authors: JL Booth, ES Duggan, VI Patel, W Wu, DM Burian, DC Hutchings, VL White, KM Coggeshall, MG Dozmorov, JP Metcalf
Microb. Pathog., 2018;0(0):.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization Control -
Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast Cancer
Authors: A Costa, Y Kieffer, A Scholer-Da, F Pelon, B Bourachot, M Cardon, P Sirven, I Magagna, L Fuhrmann, C Bernard, C Bonneau, M Kondratova, I Kuperstein, A Zinovyev, AM Givel, MC Parrini, V Soumelis, A Vincent-Sa, F Mechta-Gri
Cancer Cell, 2018;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: FACS -
Metalloprotease-disintegrin ADAM12 actively promotes the stem cell-like phenotype in claudin-low breast cancer
Authors: S Duhachek-M, Y Qi, R Wise, L Alyahya, H Li, J Hodge, A Zolkiewska
Mol. Cancer, 2017;16(1):32.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Discovery and characterization of a novel humanized anti-IL-15 antibody and its relevance for the treatment of refractory celiac disease and eosinophilic esophagitis
Authors: AP Vicari, AM Schoepfer, B Meresse, L Goffin, O Léger, S Josserand, N Guégan, S Yousefi, A Straumann, N Cerf-Bensu, HU Simon, Y Chvatchko
MAbs, 2017;0(0):0.
-
Histone deacetylase inhibitors downregulate CCR4 expression and decrease mogamulizumab efficacy in CCR4-positive mature T-cell lymphomas
Authors: A Kitadate, S Ikeda, F Abe, N Takahashi, N Shimizu, K Matsue, H Tagawa
Haematologica, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation
Authors: SN Cross, JA Potter, P Aldo, JY Kwon, M Pitruzzell, M Tong, S Guller, CV Rothlin, G Mor, VM Abrahams
J. Immunol., 2017;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: Neutralization -
Physiologically activated mammary fibroblasts promote postpartum mammary cancer
Authors: Q Guo, J Minnier, J Burchard, K Chiotti, P Spellman, P Schedin
JCI Insight, 2017;2(6):e89206.
Species: Mouse
Sample Types: Whole Cells
Applications: Neutralization -
Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology
Authors: PA Szabo, A Goswami, DM Mazzuca, K Kim, DB O'Gorman, DA Hess, ID Welch, HA Young, B Singh, JK McCormick, SM Haeryfar
J. Immunol, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways
Authors: AK Reuschl, MR Edwards, R Parker, DW Connell, L Hoang, A Halliday, H Jarvis, N Siddiqui, C Wright, S Bremang, SM Newton, P Beverley, RJ Shattock, OM Kon, A Lalvani
PLoS Pathog., 2017;13(9):e1006577.
Applications: Neutralization Control -
Isolation and characterization of equine native MSC populations
Authors: CL Esteves, TA Sheldrake, SP Mesquita, JJ Pesántez, T Menghini, L Dawson, B Péault, FX Donadeu
Stem Cell Res Ther, 2017;8(1):80.
Species: Equine
Sample Types: Whole Tissue
Applications: IHC -
The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis
Authors: GY Liou, L Bastea, A Fleming, H Döppler, BH Edenfield, DW Dawson, L Zhang, N Bardeesy, P Storz
Cell Rep, 2017;19(7):1322-1333.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Histone Deacetylase (HDAC) Inhibition Induces I?B Kinase (IKK)-dependent Interleukin-8/CXCL8 Expression in Ovarian Cancer Cells
Authors: HR Gatla, Y Zou, MM Uddin, B Singha, P Bu, A Vancura, I Vancurova
J. Biol. Chem., 2017;292(12):5043-5054.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130
Authors: X Wang, EB Miller, M Goswami, P Zhang, KE Ronning, SJ Karlen, RJ Zawadzki, EN Pugh, ME Burns
J Neuroinflammation, 2017;14(1):121.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
CXCR3 mediates ascites-directed tumor cell migration and predicts poor outcome in ovarian cancer patients
Authors: C Windmüller, D Zech, S Avril, M Boxberg, T Dawidek, B Schmalfeld, M Schmitt, M Kiechle, H Bronger
Oncogenesis, 2017;6(5):e331.
Species: Human
Sample Types: Whole Cells
-
Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice.
Authors: Jean-Mathieu Berger, Angel Loza Vald, Jesper Gromada, Norma Anderson, Jay D Horton
Journal of Lipid Research, 2017;0(0):1539-7262.
Species: Mouse
Sample Types: Plasma
Applications: Control -
Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus
Authors: J Uebele, C Stein, MT Nguyen, A Schneider, F Kleinert, O Tichá, G Bierbaum, F Götz, I Bekeredjia
PLoS Pathog., 2017;13(5):e1006387.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Equine Mesenchymal Stromal Cells retain a pericyte-like phenotype
Authors: CL Esteves, TA Sheldrake, L Dawson, T Menghini, E Rink, K Amilon, N Khan, B Peault, X Donadeu
Stem Cells Dev., 2017;0(0):.
Species: Equine
Sample Types: Whole Cells
Applications: ICC -
Induction of cathepsin B by the CXCR3 chemokines CXCL9 and CXCL10 in human breast cancer cells
Authors: H Bronger, A Karge, T Dreyer, D Zech, S Kraeft, S Avril, M Kiechle, M Schmitt
Oncol Lett, 2017;13(6):4224-4230.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling
Authors: YE Du, G Tu, G Yang, G Li, D Yang, L Lang, L Xi, K Sun, Y Chen, K Shu, H Liao, M Liu, Y Hou
Theranostics, 2017;7(16):3972-3988.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Inhibition of PCSK9 does not improve lipopolysaccharide-induced mortality in mice
Authors: JM Berger, A Loza Valde, J Gromada, N Anderson, JD Horton
J. Lipid Res., 2017;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo -
Interleukin-20 targets podocytes and is upregulated in experimental murine diabetic nephropathy
Authors: YH Hsu, HH Li, JM Sung, WY Chen, YC Hou, YH Weng, WT Lai, CH Wu, MS Chang
Exp. Mol. Med., 2017;49(3):e310.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Disruption of outer blood-retinal barrier by Toxoplasma gondii-infected monocytes is mediated by paracrinely activated FAK signaling
Authors: HB Song, HO Jun, JH Kim, YH Lee, MH Choi, JH Kim
PLoS ONE, 2017;12(4):e0175159.
Species: Human
Sample Types: Whole Tissue
Applications: Neutralization Control -
Oral fibroblasts modulate the macrophage response to bacterial challenge
Authors: R Tzach-Nahm, R Nashef, O Fleissig, A Palmon, L Shapira, A Wilensky, G Nussbaum
Sci Rep, 2017;7(1):11516.
Species: Human
Sample Types: Tissue Homogenates
Applications: Flow Cytometry -
Continuous Delivery of Neutralizing Antibodies Elevate CCL2 Levels in Mice Bearing MCF10CA1d Breast Tumor Xenografts
Authors: M Yao, C Smart, Q Hu, N Cheng
Transl Oncol, 2017;10(5):734-743.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Histone deacetylase 3 is required for iNKT cell development
Authors: P Thapa, S Romero Aro, JY Chung, DB Sant'Angel, VS Shapiro
Sci Rep, 2017;7(1):5784.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
IL-6 trans-signaling is another pathway to upregulate Osteopontin
Cytokine, 2016;90(0):88-95.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Mesenchymal Stem Cell-Educated Macrophages Ameliorate LPS-Induced Systemic Response
Authors: Yaoqin Hu
Mediators Inflamm, 2016;2016(0):3735452.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
PLoS ONE, 2016;11(4):e0153811.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V1.7 target sequences and block of human Na V1.7 currents
F1000Res, 2016;5(0):2764.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion
PLoS ONE, 2016;11(7):e0160108.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
MECHANICAL VENTILATION AUGMENTS POLY(I:C)INDUCED LUNG INJURY VIA A WISP1-INTEGRIN ?3 DEPENDENT PATHWAY IN MICE
Authors: Quan Li
Mol. Med., 2016;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Human pancreatic cancer cells induce a MyD88-dependent stromal response to promote a tumor-tolerant immune microenvironment
Cancer Res., 2016;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
[64Cu]XYIMSR-06: A dual-motif CAIX ligand for PET imaging of clear cell renal cell carcinoma
Authors: I Minn, SM Koo, HS Lee, M Brummet, SP Rowe, MA Gorin, P Sysa-Shah, WD Lewis, HH Ahn, Y Wang, SR Banerjee, RC Mease, S Nimmagadda, ME Allaf, MG Pomper, X Yang
Oncotarget, 2016;7(35):56471-56479.
Species: Mink
Sample Types: Whole Cells
Applications: Neutralization -
IL-17E synergizes with EGF and confers in vitro resistance to EGFR-targeted therapies in TNBC cells
Authors: Y Merrouche, J Fabre, H Cure, C Garbar, C Fuselier, J Bastid, F Antonicell, R Al-Daccak, A Bensussan, J Giustinian
Oncotarget, 2016;7(33):53350-53361.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses
Authors: Wan-Chien Cheng
Eur J Immunol, 2016;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Control -
miR-720 is a downstream target of an ADAM8-induced ERK signaling cascade that promotes the migratory and invasive phenotype of triple-negative breast cancer cells
Authors: SG Das, M Romagnoli, ND Mineva, S Barillé-Ni, P Jézéquel, M Campone, GE Sonenshein
Breast Cancer Res, 2016;18(1):40.
Species: Human
Sample Types: Whole Cells
Applications: Functional Assay -
TGF-?1 Is Present at High Levels in Wound Fluid from Breast Cancer Patients Immediately Post-Surgery, and Is Not Increased by Intraoperative Radiation Therapy (IORT)
PLoS ONE, 2016;11(9):e0162221.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1
PLoS ONE, 2016;11(11):e0167324.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Fibroblast Activation Protein (FAP) Accelerates Collagen Degradation and Clearance from Lungs in Mice
Authors: MH Fan, Q Zhu, HH Li, HJ Ra, S Majumdar, DL Gulick, JA Jerome, DH Madsen, M Christofid, DW Speicher, WW Bachovchin, C Feghali-Bo, E Puré
J. Biol. Chem., 2016;291(15):8070-89.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Immunoprecipitation -
Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner.
Authors: Anguille S, Van Acker H, Van den Bergh J, Willemen Y, Goossens H, Van Tendeloo V, Smits E, Berneman Z, Lion E
PLoS ONE, 2015;10(5):e0123340.
-
SDF-1alpha is a novel autocrine activator of platelets operating through its receptor CXCR4.
Authors: Walsh T, Harper M, Poole A
Cell Signal, 2015;27(1):37-46.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients.
Authors: Martinez L, Labovsky V, Calcagno M, Davies K, Garcia Rivello H, Bianchi M, Wernicke A, Fernandez Vallone V, Chasseing N
PLoS ONE, 2015;10(3):e0121421.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4+ T cells.
Authors: Schmetterer K, Neunkirchner A, Wojta-Stremayr D, Leitner J, Steinberger P, Pickl W
FASEB J, 2015;29(3):759-71.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Expression of the immune regulation antigen CD70 in osteosarcoma.
Authors: Pahl J, Santos S, Kuijjer M, Boerman G, Sand L, Szuhai K, Cleton-Jansen A, Egeler R, Bovee J, Schilham M, Lankester A
Cancer Cell Int, 2015;15(0):31.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Bortezomib inhibits expression of TGF-beta1, IL-10, and CXCR4, resulting in decreased survival and migration of cutaneous T cell lymphoma cells.
Authors: Chang T, Poltoratsky V, Vancurova I
J Immunol, 2015;194(6):2942-53.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition.
Authors: Mizuuchi Y, Aishima S, Ohuchida K, Shindo K, Fujino M, Hattori M, Miyazaki T, Mizumoto K, Tanaka M, Oda Y
Lab Invest, 2015;95(2):193-206.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
IL-18 Is Involved in Eosinophil-Mediated Tumoricidal Activity against a Colon Carcinoma Cell Line by Upregulating LFA-1 and ICAM-1.
Authors: Gatault S, Delbeke M, Driss V, Sarazin A, Dendooven A, Kahn J, Lefevre G, Capron M
J Immunol, 2015;195(5):2483-92.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Interleukin-10 receptor-1 expression in monocyte-derived antigen-presenting cell populations: dendritic cells partially escape from IL-10's inhibitory mechanisms.
Authors: von Lanzenauer S, Wolk K, Hoflich C, Kunz S, Grunberg B, Docke W, Reineke U, Asadullah K, Sterry W, Volk H, Sabat R
Genes Immun, 2015;16(1):8-14.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
CXCL8 and CCL20 Enhance Osteoclastogenesis via Modulation of Cytokine Production by Human Primary Osteoblasts.
Authors: Pathak J, Bakker A, Verschueren P, Lems W, Luyten F, Klein-Nulend J, Bravenboer N
PLoS ONE, 2015;10(6):e0131041.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor.
Authors: Agrawal V, Jaiswal M, Mallers T, Katara G, Gilman-Sachs A, Beaman K, Hirsch E
Sci Rep, 2015;5(0):9410.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.
Authors: Zmora P, Moldenhauer A, Hofmann-Winkler H, Pohlmann S
PLoS ONE, 2015;10(9):e0138380.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot Control -
Adipose Stromal Cell Contact with Endothelial Cells Results in Loss of Complementary Vasculogenic Activity Mediated by Induction of Activin A.
Authors: Merfeld-Clauss S, Lupov I, Lu H, March K, Traktuev D
Stem Cells, 2015;33(10):3039-51.
Species: Human
Sample Types: Cell Culture Supernates
Applications: Neutralization -
The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity.
Authors: Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister H, Alexander T, Hiepe F, Kumpfel T, Crawford H, Wekerle H, Hohlfeld R, Lichtenthaler S, Meinl E
J Immunol, 2015;194(2):542-52.
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
J Neuroinflammation, 2015;12(0):119.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
Authors: Kowalewska P, Patrick A, Fox-Robichaud A
PLoS ONE, 2014;9(9):e104537.
Species: Mouse
Sample Types: In Vivo
Applications: IHC-Fr -
Mesenchymal stem cell contact promotes CCN1 splicing and transcription in myeloma cells.
Authors: Dotterweich J, Ebert R, Kraus S, Tower R, Jakob F, Schutze N
Cell Commun Signal, 2014;12(0):36.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
RepSox slows decay of CD34+ acute myeloid leukemia cells and decreases T cell immunoglobulin mucin-3 expression.
Authors: Jajosky A, Coad J, Vos J, Martin K, Senft J, Wenger S, Gibson L
Stem Cells Transl Med, 2014;3(7):836-48.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
IL-17-induced CXCL12 recruits B cells and induces follicle formation in BALT in the absence of differentiated FDCs.
Authors: Fleige H, Ravens S, Moschovakis G, Bolter J, Willenzon S, Sutter G, Haussler S, Kalinke U, Prinz I, Forster R
J Exp Med, 2014;211(4):643-51.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
J Immunol, 2014;193(5):2297-305.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Phenotypic diversity of breast cancer-related mutations in metalloproteinase-disintegrin ADAM12.
Authors: Qi, Yue, Duhachek-Muggy, Sara, Li, Hui, Zolkiewska, Anna
PLoS ONE, 2014;9(3):e92536.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
The extracellular matrix protein MAGP1 supports thermogenesis and protects against obesity and diabetes through regulation of TGF-beta.
Authors: Craft C, Pietka T, Schappe T, Coleman T, Combs M, Klein S, Abumrad N, Mecham R
Diabetes, 2014;63(6):1920-32.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Negative regulation of Toll-like receptor-4 signaling through the binding of glycosylphosphatidylinositol-anchored glycoprotein, CD14, with the sialic acid-binding lectin, CD33.
Authors: Ishida A, Akita K, Mori Y, Tanida S, Toda M, Inoue M, Nakada H
J Biol Chem, 2014;289(36):25341-50.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
MicroRNA-147b regulates vascular endothelial barrier function by targeting ADAM15 expression.
Authors: Chatterjee V, Beard R, Reynolds J, Haines R, Guo M, Rubin M, Guido J, Wu M, Yuan S
PLoS ONE, 2014;9(10):e110286.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Skeletal muscle expression of the adhesion-GPCR CD97: CD97 deletion induces an abnormal structure of the sarcoplasmatic reticulum but does not impair skeletal muscle function.
Authors: Zyryanova T, Schneider R, Adams V, Sittig D, Kerner C, Gebhardt C, Ruffert H, Glasmacher S, Hepp P, Punkt K, Neuhaus J, Hamann J, Aust G
PLoS ONE, 2014;9(6):e100513.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Authors: Zmora P, Blazejewska P, Moldenhauer A, Welsch K, Nehlmeier I, Wu Q, Schneider H, Pohlmann S, Bertram S
J Virol, 2014;88(20):12087-97.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Surfactant protein D attenuates sub-epithelial fibrosis in allergic airways disease through TGF-ss
Authors: Ogawa H, Ledford J, Mukherjee S, Aono Y, Nishioka Y, Lee J, Izumi K, Hollingsworth J
Respir Res, 2014;15(1):143.
Species: Human
Sample Types: In Vivo
Applications: Control -
Crosstalk between mitochondrial ROS and depolarization in the potentiation of TRAIL-induced apoptosis in human tumor cells.
Authors: Suzuki-Karasaki M, Ochiai T, Suzuki-Karasaki Y
Int J Oncol, 2014;44(2):616-28.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Atmospheric gas plasma-induced ROS production activates TNF-ASK1 pathway for the induction of melanoma cancer cell apoptosis.
Authors: Ishaq, Musarat, Kumar, Shailesh, Varinli, Hilal, Han, Zhao Jun, Rider, Amanda E, Evans, Margaret, Murphy, Anthony, Ostrikov, Kostya
Mol Biol Cell, 2014;25(9):1523-31.
Species: Human
Sample Types: Cell Lysates
Applications: Neutralization -
Protein C inhibitor (PCI) binds to phosphatidylserine exposing cells with implications in the phagocytosis of apoptotic cells and activated platelets.
Authors: Rieger D, Assinger A, Einfinger K, Sokolikova B, Geiger M
PLoS ONE, 2014;9(7):e101794.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells.
Authors: Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, Latge J, Elbim C
J Immunol, 2014;192(11):5332-42.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control -
Chemokine receptor CXCR7 is a functional receptor for CXCL12 in brain endothelial cells.
Authors: Liu Y, Carson-Walter E, Walter K
PLoS ONE, 2014;9(8):e103938.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Tumour necrosis factor-alpha regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappaB and AP-1.
Authors: Kankaanranta H, Ilmarinen P, Zhang X, Adcock I, Lahti A, Barnes P, Giembycz M, Lindsay M, Moilanen E
PLoS ONE, 2014;9(2):e90298.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
Authors: Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A
Nat Immunol, 2014;15(4):354-64.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
Genetic evolution of T-cell resistance in the course of melanoma progression.
Authors: Sucker A, Zhao F, Real B, Heeke C, Bielefeld N, Mabetaen S, Horn S, Moll I, Maltaner R, Horn P, Schilling B, Sabbatino F, Lennerz V, Kloor M, Ferrone S, Schadendorf D, Falk C, Griewank K, Paschen A
Clin Cancer Res, 2014;20(24):6593-604.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
An important role of the SDF-1/CXCR4 axis in chronic skin inflammation.
Authors: Zgraggen, Silvana, Huggenberger, Reto, Kerl, Katrin, Detmar, Michael
PLoS ONE, 2014;9(4):e93665.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Dual regulation of osteopontin production by TLR stimulation in dendritic cells.
Authors: Salvi V, Scutera S, Rossi S, Zucca M, Alessandria M, Greco D, Bosisio D, Sozzani S, Musso T
J Leukoc Biol, 2013;94(1):147-58.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Transendothelial migration enables subsequent transmigration of neutrophils through underlying pericytes.
Authors: Ayres-Sander C, Lauridsen H, Maier C, Sava P, Pober J, Gonzalez A
PLoS ONE, 2013;8(3):e60025.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry Control -
Antibody-mediated targeting of the Orai1 calcium channel inhibits T cell function.
Authors: Cox J, Hussell S, Sondergaard H, Roepstorff K, Bui J, Deer J, Zhang J, Li Z, Lamberth K, Kvist P, Padkjaer S, Haase C, Zahn S, Odegard V
PLoS ONE, 2013;8(12):e82944.
Species: Mouse
Sample Types: Whole Cells
Applications: Flow Cytometry -
Astrocytes directly influence tumor cell invasion and metastasis in vivo.
Authors: Wang, Ling, Cossette, Stephani, Rarick, Kevin R, Gershan, Jill, Dwinell, Michael, Harder, David R, Ramchandran, Ramani
PLoS ONE, 2013;8(12):e80933.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Selective blockade of matrix metalloprotease-14 with a monoclonal antibody abrogates invasion, angiogenesis, and tumor growth in ovarian cancer.
Authors: Kaimal R, Aljumaily R, Tressel S, Pradhan R, Covic L, Kuliopulos A, Zarwan C, Kim Y, Sharifi S, Agarwal A
Cancer Res, 2013;73(8):2457-67.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
IL-1 Family Members IL-18 and IL-33 Upregulate the Inflammatory Potential of Differentiated Human Th1 and Th2 Cultures.
Authors: Blom L, Poulsen L
J Immunol, 2012;189(9):4331-7.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Activated Human CD4+CD45RO+ Memory T-Cells Indirectly Inhibit NLRP3 Inflammasome Activation through Downregulation of P2X7R Signalling.
Authors: Beynon V, Quintana FJ, Weiner HL
PLoS ONE, 2012;7(6):e39576.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Proinflammatory actions of visfatin/nicotinamide phosphoribosyltransferase (Nampt) involve regulation of insulin signaling pathway and Nampt enzymatic activity.
Authors: Jacques C, Holzenberger M, Mladenovic Z
J. Biol. Chem., 2012;287(18):15100-8.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Macrophages induce differentiation of plasma cells through CXCL10/IP-10.
J. Exp. Med., 2012;209(10):1813-23.
Species: Human
Sample Types: Whole Cells
Applications: Control -
IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival.
Authors: Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME
PLoS ONE, 2012;7(7):e40620.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities.
Authors: Tel J, Smits E, Anguille S, Joshi R, Figdor C, de Vries I
Blood, 2012;120(19):3936-44.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay -
Cytotoxicity of CD56(bright) NK cells towards autologous activated CD4+ T cells is mediated through NKG2D, LFA-1 and TRAIL and dampened via CD94/NKG2A.
Authors: Nielsen N, Odum N, Urso B, Lanier LL, Spee P
PLoS ONE, 2012;7(2):e31959.
Species: Human
Sample Types: Whole Cells
Applications: Control -
ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytes.
Authors: Wilhelmsen K, Mesa K, Lucero J, Xu F, Hellman J
J Biol Chem, 2012;287(32):26478-94.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Daily exposure to dust alters innate immunity.
Authors: Sahlander K, Larsson K, Palmberg L
PLoS ONE, 2012;7(2):e31646.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Adenovirus-engineered human dendritic cells induce natural killer cell chemotaxis via CXCL8/IL-8 and CXCL10/IP-10.
Authors: Vujanovic, Lazar, Ballard, Wenners, Thorne, Stephen, Vujanovic, Nikola L, Butterfield, Lisa H
Oncoimmunology, 2012;1(4):448-457.
Species: Mouse
Sample Types: In Vivo
Applications: Neutralization -
Brain-derived neurotrophic factor is increased in serum and skin levels of patients with chronic spontaneous urticaria.
Authors: Rossing K, Novak N, Mommert S, Pfab F, Gehring M, Wedi B, Kapp A, Raap U
Clin. Exp. Allergy, 2011;41(10):1392-1399.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Cocaine hijacks sigma1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS.
Authors: Yao H, Kim K, Duan M, Hayashi T, Guo M, Morgello S, Prat A, Wang J, Su TP, Buch S
J. Neurosci., 2011;31(16):5942-55.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Bovine lactoferrin counteracts Toll-like receptor mediated activation signals in antigen presenting cells.
Authors: Puddu P, Latorre D, Carollo M, Catizone A, Ricci G, Valenti P, Gessani S
PLoS ONE, 2011;6(7):e22504.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells.
Authors: Yamakawa N, Uchida T, Matthay MA, Makita K
Am. J. Physiol. Lung Cell Mol. Physiol., 2011;300(4):L516-25.
Species: Rat
Sample Types: Whole Cells
Applications: Control -
Expression and regulation of CCL15 by human airway smooth muscle cells.
Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
Clin. Exp. Allergy, 2011;42(1):85-94.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.
Authors: Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E
Nat. Med., 2011;17(11):1498-503.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
IL-17A-producing gammadelta T and Th17 lymphocytes mediate lung inflammation but not fibrosis in experimental silicosis.
Authors: Lo Re S, Dumoutier L, Couillin I, Van Vyve C, Yakoub Y, Uwambayinema F, Marien B, van den Brule S, Van Snick J, Uyttenhove C, Ryffel B, Renauld JC, Lison D, Huaux F
J. Immunol., 2010;184(11):6367-77.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Toll-like receptor 9 ligands enhance mesenchymal stem cell invasion and expression of matrix metalloprotease-13.
Authors: Nurmenniemi S, Kuvaja P, Lehtonen S
Exp. Cell Res., 2010;316(16):2676-82.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Stromal cell-derived factor-1 is essential for photoreceptor cell protection in retinal detachment.
Authors: Otsuka H, Arimura N, Sonoda S
Am. J. Pathol., 2010;177(5):2268-77.
Species: Rat
Sample Types: In Vivo
Applications: Control -
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Authors: Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, Kochert K, Bouhlel MA, Richter J, Soler E, Stadhouders R, Johrens K, Wurster KD, Callen DF, Harte MF, Giefing M, Barlow R, Stein H, Anagnostopoulos I, Janz M, Cockerill PN, Siebert R, Dorken B, Bonifer C, Mathas S
Nat. Med., 2010;16(5):571-9.
Species: Human
Sample Types: Cell Lysates
Applications: Control -
CXCR7 protein is not expressed on human or mouse leukocytes.
Authors: Berahovich RD, Zabel BA, Penfold ME, Lewen S, Wang Y, Miao Z, Gan L, Pereda J, Dias J, Slukvin II, McGrath KE, Jaen JC, Schall TJ
J. Immunol., 2010;185(9):5130-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Iris pigment epithelial cells express a functional lipopolysaccharide receptor complex.
Authors: Chui JJ, Li MW, Di Girolamo N, Chang JH, McCluskey PJ, Wakefield D
Invest. Ophthalmol. Vis. Sci., 2010;51(5):2558-67.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control -
IRF5 is required for late-phase TNF secretion by human dendritic cells.
Authors: Krausgruber T, Saliba D, Ryzhakov G
Blood, 2010;115(22):4421-30.
Species: Human
Sample Types: Whole Cells
Applications: Control -
CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1.
Authors: Kollmar O, Rupertus K, Scheuer C, Nickels RM, Haberl GC, Tilton B, Menger MD, Schilling MK
Int. J. Cancer, 2010;126(6):1302-15.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Erythropoietin exerts anti-epileptic effects with the suppression of aberrant new cell formation in the dentate gyrus and upregulation of neuropeptide Y in seizure model of rats.
Authors: Kondo A, Shingo T, Yasuhara T, Kuramoto S, Kameda M, Kikuchi Y, Matsui T, Miyoshi Y, Agari T, Borlongan CV, Date I
Brain Res., 2009;1296(0):127-36.
Species: Rat
Sample Types: In Vivo
Applications: Control -
The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells.
Authors: Nevo I, Sagi-Assif O, Meshel T, Ben-Baruch A, Johrer K, Greil R, Trejo LE, Kharenko O, Feinmesser M, Yron I, Witz IP
Cancer Lett., 2009;273(1):127-39.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells.
Authors: Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, Nausch N, Tuettenberg J, Steinle A, Cerwenka A, Schadendorf D, Paschen A
Int. J. Cancer, 2009;124(7):1594-604.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Plasmid-encoded interleukin-15 receptor alpha enhances specific immune responses induced by a DNA vaccine in vivo.
Authors: Kraynyak KA, Kutzler MA, Cisper NJ, Laddy DJ, Morrow MP, Waldmann TA, Weiner DB
Hum. Gene Ther., 2009;20(10):1143-56.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
CD69+ CD4+ CD25- T cells, a new subset of regulatory T cells, suppress T cell proliferation through membrane-bound TGF-beta 1.
Authors: Han Y, Guo Q, Zhang M, Chen Z, Cao X
J. Immunol., 2009;182(1):111-20.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6.
Authors: Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P
J. Immunol., 2008;181(4):2772-80.
Species: Human
Sample Types: Whole Cells
Applications: Control -
pVHL co-ordinately regulates CXCR4/CXCL12 and MMP2/MMP9 expression in human clear-cell renal cell carcinoma.
Authors: Struckmann K, Mertz K, Steu S, Storz M, Staller P, Krek W, Schraml P, Moch H
J. Pathol., 2008;214(4):464-71.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Characterization of human skin-derived mesenchymal stem cell proliferation rate in different growth conditions.
Authors: Riekstina U, Muceniece R, Cakstina I, Muiznieks I, Ancans J
Cytotechnology, 2008;58(3):153-62.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Reversible commitment to differentiation by human multipotent stromal cells in single-cell-derived colonies.
Authors: Ylostalo J, Bazhanov N, Prockop DJ
Exp. Hematol., 2008;36(10):1390-402.
Species: Human
Sample Types: Whole Cells
Applications: Control -
TLR7 Agonist 852A Inhibition of Tumor Cell Proliferation Is Dependent on Plasmacytoid Dendritic Cells and Type I IFN.
Authors: Inglefield JR, Dumitru CD, Alkan SS, Gibson SJ, Lipson KE, Tomai MA, Larson CJ, Vasilakos JP
J. Interferon Cytokine Res., 2008;28(4):253-63.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Cyclic regulation of T-Bet and GATA-3 in human endometrium.
Authors: Inman D, Kawana K, Schust D
Reprod Sci, 2008;15(1):83-90.
Species: Human
Sample Types: Whole Tissue
Applications: Control -
Characterization of naturally occurring CD4+CD25+ regulatory T cells in rhesus monkeys.
Authors: Haanstra KG, van der Maas MJ, 't Hart BA, Jonker M
Transplantation, 2008;85(8):1185-92.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Control -
IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells.
Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA
J. Immunol., 2007;178(4):2018-27.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction.
Authors: Bolovan-Fritts CA, Spector SA
Blood, 2007;111(1):175-82.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Effects of type I interferons on the adjuvant properties of plasmid granulocyte-macrophage colony-stimulating factor in vivo.
Authors: Qin L, Greenland JR, Moriya C
J. Virol., 2007;81(19):10606-13.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge.
Authors: He R, Oyoshi MK, Jin H, Geha RS
Proc. Natl. Acad. Sci. U.S.A., 2007;104(40):15817-22.
Species: Mouse
Sample Types: In Vivo
Applications: Control -
Human epithelial cells establish direct antifungal defense through TLR4-mediated signaling.
Authors: Weindl G, Naglik JR, Kaesler S, Biedermann T, Hube B, Korting HC, Schaller M
J. Clin. Invest., 2007;117(12):3664-3672.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Hepatitis C virus (HCV)-specific CD8+ cells produce transforming growth factor beta that can suppress HCV-specific T-cell responses.
Authors: Alatrakchi N, Graham CS, van der Vliet HJ, Sherman KE, Exley MA, Koziel MJ
J. Virol., 2007;81(11):5882-92.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Endothelial cells of human colorectal cancer and healthy colon reveal phenotypic differences in culture.
Authors: Schellerer VS, Croner RS, Weinlander K, Hohenberger W, Sturzl M, Naschberger E
Lab. Invest., 2007;87(11):1159-70.
Species: Human
Sample Types: Whole Cells
Applications: Control -
T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue.
Authors: Withers DR, Fiorini C, Fischer RT, Ettinger R, Lipsky PE, Grammer AC
Blood, 2007;109(11):4856-64.
Species: Human
Sample Types: Whole Cells
Applications: Control -
S100A11, an dual mediator for growth regulation of human keratinocytes.
Authors: Sakaguchi M, Sonegawa H, Murata H, Kitazoe M, Futami J, Kataoka K, Yamada H, Huh NH
Mol. Biol. Cell, 2007;19(1):78-85.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes.
Authors: Kanda N, Watanabe S
Endocrinology, 2007;148(5):2317-25.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
Authors: Ball SG, Shuttleworth CA, Kielty CM
J. Cell Biol., 2007;177(3):489-500.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Loss of IL-7 receptor alpha on CD4+ T cells defines terminally differentiated B cell-helping effector T cells in a B cell-rich lymphoid tissue.
Authors: Lim HW, Kim CH
J. Immunol., 2007;179(11):7448-56.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Induction of host chemotactic response by Encephalitozoon spp.
Authors: Fischer J, West J, Agochukwu N, Suire C, Hale-Donze H
Infect. Immun., 2007;75(4):1619-25.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Peroxisome proliferator-activated receptor-gamma agonists inhibit respiratory syncytial virus-induced expression of intercellular adhesion molecule-1 in human lung epithelial cells.
Authors: Arnold R, Neumann M, Konig W
Immunology, 2007;121(1):71-81.
Species: Human
Sample Types: Whole Cells
Applications: Control -
LPS/CD14 activation triggers SGLT-1-mediated glucose uptake and cell rescue in intestinal epithelial cells via early apoptotic signals upstream of caspase-3.
Authors: Yu LC, Turner JR, Buret AG
Exp. Cell Res., 2006;312(17):3276-86.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
Clin. Immunol., 2006;120(2):220-31.
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Hypoxia modifies the transcriptome of primary human monocytes: modulation of novel immune-related genes and identification of CC-chemokine ligand 20 as a new hypoxia-inducible gene.
Authors: Bosco MC, Puppo M, Santangelo C, Anfosso L, Pfeffer U, Fardin P, Battaglia F, Varesio L
J. Immunol., 2006;177(3):1941-55.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
Authors: Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
Blood, 2006;107(9):3617-23.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Increased levels of neutrophil-activating peptide-2 in acute coronary syndromes: possible role of platelet-mediated vascular inflammation.
Authors: Smith C, Damas JK, Otterdal K, ØIe E, Sandberg WJ, Yndestad A, Waehre T, Scholz H, Endresen K, Olofsson PS, Halvorsen B, Gullestad L, Froland SS, Hansson GK, Aukrust P
J. Am. Coll. Cardiol., 2006;48(8):1591-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.
Authors: Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF
Proc. Natl. Acad. Sci. U.S.A., 2006;103(9):3333-8.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes.
Authors: Koelle DM, Huang J, Hensel MT, McClurkan CL
J. Virol., 2006;80(6):2863-72.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
Authors: Ebert EC, Mehta V
Cell. Immunol., 2006;241(1):7-13.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis.
Authors: Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS
Arthritis Rheum., 2006;54(9):2722-33.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts.
Authors: Hatfield K, Ryningen A, Corbascio M, Bruserud O
Int. J. Cancer, 2006;119(10):2313-21.
Species: Human
Sample Types: Whole Cells
Applications: Control -
FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis.
Authors: Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP
Development, 2005;132(6):1223-34.
Species: Mouse
Sample Types: Whole Cells
Applications: Control -
Astroglial-derived lymphotoxin-alpha exacerbates inflammation and demyelination, but not remyelination.
Authors: Plant SR, Arnett HA, Ting JP
Glia, 2005;49(1):1-14.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control -
Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
J. Immunol., 2005;174(4):2376-86.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Human T cells constitutively express IL-15 that promotes ex vivo T cell homeostatic proliferation through autocrine/juxtacrine loops.
Authors: Miranda-Carus ME, Benito-Miguel M, Llamas MA, Balsa A, Martin-Mola E
J. Immunol., 2005;175(6):3656-62.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Protection of human conjunctival fibroblasts from NO-induced apoptosis by interleukin-4 or interleukin-13.
Authors: Fujitsu Y, Fukuda K, Kimura K, Seki K, Kumagai N, Nishida T
Invest. Ophthalmol. Vis. Sci., 2005;46(3):797-802.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
J. Immunol., 2004;172(9):5213-21.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses.
Authors: Lim HW, Hillsamer P, Kim CH
J. Clin. Invest., 2004;114(11):1640-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
IL1beta and TNFalpha differently modulate CXCL13 chemokine in stromal cells and osteoblasts isolated from osteoarthritis patients: evidence of changes associated to cell maturation.
Authors: Lisignoli G, Cristino S, Toneguzzi S, Grassi F, Piacentini A, Cavallo C, Facchini A, Mariani E
Exp. Gerontol., 2004;39(4):659-65.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Human cytomegalovirus-encoded interleukin-10 homolog inhibits maturation of dendritic cells and alters their functionality.
Authors: Chang WL, Baumgarth N, Yu D, Barry PA
J. Virol., 2004;78(16):8720-31.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Three-dimensional porous alginate scaffolds provide a conducive environment for generation of well-vascularized embryoid bodies from human embryonic stem cells.
Authors: Gerecht-Nir S, Cohen S, Ziskind A, Itskovitz-Eldor J
Biotechnol. Bioeng., 2004;88(3):313-20.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.
Authors: Artavanis-Tsakonas K, Eleme K, McQueen KL, Cheng NW, Parham P, Davis DM, Riley EM
J. Immunol., 2003;171(10):5396-405.
Species: Human
Sample Types: Whole Cells
Applications: Control -
In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
Authors: Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y
Blood, 2003;102(12):4084-9.
Species: Human
Sample Types: Whole Cells
Applications: Control -
Soluble CD54 induces human endothelial cells ex vivo expansion useful for cardiovascular regeneration and tissue engineering application.
Authors: Malara N, Trunzo V, Musolino G, Aprigliano S, Rotta G, Macrina L, Limongi T, Gratteri S, Di Fabrizio E, Renzulli A, Fini M, Mollace V
Int J Cardiol Heart Vasc, 0;6(0):48-53.
Species: Human
Sample Types: Whole Cells
Applications: Neutralization -
Tumor necrosis factor-alpha-accelerated degradation of type I collagen in human skin is associated with elevated matrix metalloproteinase (MMP)-1 and MMP-3 ex vivo.
Authors: Agren M, Schnabel R, Christensen L, Mirastschijski U
Eur J Cell Biol, 0;94(1):12-21.
Species: Human
Sample Types: Whole Tissue
Applications: Control
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used as a negative control
Need optimization of your specific cell types and use the same amount as the primary antibody.
We used this as an Isotype Control for our Endothelial Chemotaxis Assay experiments. Conditioned Medium from Breast cancer cells mixed with IgG1 Isotype Control was used to compare Conditioned Medium containing cytokines (IL6, IL8, IL1B) neutralization antibody cocktail.
Cancer Res; 78(5) March 1, 2018 (Fig 6F)
PFA 4% fixation. Used at 94ug/mL. No signal until 120-250msec of acquisition time.