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Mouse IL-1 beta/IL-1F2 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
15.6 - 1,000 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-1 beta/IL-1F2. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

Data Example

Mouse IL-1 beta / IL-1F2 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of IL-1 alpha, IL-1 beta, and the IL-1 receptor antagonist (IL-1ra). IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions (1). IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is seen. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulindependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases (2-5). 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid (aa) level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa (6, 7). Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response (2, 8). Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide (9-11), but evidence suggests that these factors can be secreted by non-classical pathways (12, 13). A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity (14). The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form (13, 15). Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes (16, 17). The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells (18). The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 aa, whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function (19). The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction (20). IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 (21, 22). Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines (23, 24). In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses (25).

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL of Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Mouse IL-1 beta/IL-1F2 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

371 Citations: Showing 1 - 10
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  1. Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
    Authors: YH Su, JY Lin
    International Journal of Molecular Sciences, 2022;23(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses
    Authors: S Ndeupen, A Bouteau, C Herbst, Z Qin, S Jacobsen, NE Powers, Z Hutchins, D Kurup, LZ Diba, M Watson, H Ramage, BZ Igyártó
    PloS Pathogens, 2022;18(1):e1010255.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. Acute exposure to phthalates during recovery from a myocardial infarction induces greater inflammasome activation in male C57bl/6N mice
    Authors: A Schwendt, JB Chammas, LE Chalifour
    Toxicology and Applied Pharmacology, 2022;440(0):115954.
    Species: Mouse
    Sample Types: Plasma
  4. Nociceptor-derived Reg3gamma prevents endotoxic death by targeting kynurenine pathway in microglia
    Authors: E Sugisawa, T Kondo, Y Kumagai, H Kato, Y Takayama, K Isohashi, E Shimosegaw, N Takemura, Y Hayashi, T Sasaki, MM Martino, M Tominaga, K Maruyama
    Cell Reports, 2022;38(10):110462.
    Species: Mouse
    Sample Types: Plasma
  5. Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice
    Authors: PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini
    PLoS ONE, 2022;17(1):e0261667.
    Species: Mouse
    Sample Types: Tissue Homogenates
  6. Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens
    Authors: AI Kanno, D Boraschi, LCC Leite, D Rodriguez
    Vaccines, 2022;10(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands
    Authors: F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani
    Journal of leukocyte biology, 2022;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
    Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  9. The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
    Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
    Biomedicines, 2022;10(1):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  10. The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases
    Authors: PR da Silva, RF do Espírit, CO Melo, FE Pachú Cava, TB Costa, YV Barbosa, YMSM E Silva, NF de Sousa, CF Villarreal, RO de Moura, VL Dos Santos
    Pharmaceutics, 2022;14(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis
    Authors: M Mae, MI Alam, Y Yamashita, Y Ozaki, K Higuchi, SM Ziauddin, JL Montenegro, E Sakai, T Tsukuba, A Yoshimura
    International Journal of Molecular Sciences, 2021;22(22):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  12. Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor
    Authors: B Venkataram, S Almarzooqi, V Raj, AT Alhassani, AS Alhassani, KJ Ahmed, VS Subramania, SK Ojha, S Attoub, TE Adrian, SB Subramanya
    Nutrients, 2021;13(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  13. &beta-Glucan-stimulated neutrophil secretion of IL-1&alpha is independent of GSDMD and mediated through extracellular vesicles
    Authors: B Ratitong, M Marshall, E Pearlman
    Cell Reports, 2021;35(7):109139.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  14. Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice
    Authors: Y Mishima, T Osaki, A Shimada, S Kamiya, S Hasegawa-I
    Scientific Reports, 2021;11(1):4640.
    Species: Mouse
    Sample Types: Serum
  15. Fatty Acids and a High-Fat Diet Induce Epithelial-Mesenchymal Transition by Activating TGF&beta and &beta-Catenin in Liver Cells
    Authors: O Kwapisz, J Górka, A Korlatowic, J Kotlinowsk, A Waligórska, P Marona, N Pydyn, JW Dobrucki, J Jura, K Miekus
    International Journal of Molecular Sciences, 2021;22(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  16. NLRP3-Inflammasome Inhibition during Respiratory Virus Infection Abrogates Lung Immunopathology and Long-Term Airway Disease Development
    Authors: CA Malinczak, CF Schuler, AJ Duran, AJ Rasky, MM Mire, G Núñez, NW Lukacs, W Fonseca
    Viruses, 2021;13(4):.
    Species: Mouse
    Sample Types: BALF
  17. Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-kappaB pathway in presenilin 1/2 conditional double knockout mice
    Authors: J Gao, L Wang, C Zhao, Y Wu, Z Lu, Y Gu, Z Ba, X Wang, J Wang, Y Xu
    Journal of leukocyte biology, 2021;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  18. STAT6-Dependent Exacerbation of House Dust Mite-Induced Allergic Airway Disease in Mice by Multi-Walled Carbon Nanotubes
    Authors: MD Ihrie, KS Duke, KA Shipkowski, DJ You, HY Lee, AJ Taylor-Jus, JC Bonner
    NanoImpact, 2021;22(0):.
    Species: Mouse
    Sample Types: BALF
  19. Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
    Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
    Cell Reports, 2021;36(12):109726.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. The SNX-482 peptide from Hysterocrates gigas spider acts as an immunomodulatory molecule activating macrophages
    Authors: J Munhoz, R Thomé, A Rostami, LLW Ishikawa, L Verinaud, C Rapôso
    Peptides, 2021;146(0):170648.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  21. Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
    Authors: BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen
    Nature Communications, 2021;12(1):7336.
    Species: Mouse
    Sample Types: Tissue Homogenates
  22. Anti-IAPP Monoclonal Antibody Improves Clinical Symptoms in a Mouse Model of Type 2 Diabetes
    Authors: AS Vogt, ES Roesti, MO Mohsen, A Leonchiks, M Vogel, MF Bachmann
    Vaccines, 2021;9(11):.
    Species: Mouse
    Sample Types: Serum
  23. Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases
    Authors: PM Soriano-Te, G García-Laí, M Marco-Salv, J Pardo, M Arias, C DeFord, I Merfort, MJ Vicent, P Pelegrín, M Sancho, M Orzáez
    Cell Death & Disease, 2021;12(12):1155.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  24. Generation and utilization of a HEK-293T murine GM-CSF expressing cell line
    Authors: EK Robinson, S Covarrubia, S Zhou, S Carpenter
    PLoS ONE, 2021;16(4):e0249117.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen
    Authors: LI Dos Santos, TA Torres, SQ Diniz, R Gonçalves, G Caballero-, G Núñez, RT Gazzinelli, KJ Maloy, L Ribeiro do
    Cell Reports, 2021;34(2):108613.
    Species: Mouse
    Sample Types: Serum
  26. Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice
    Authors: A Isaacs-Ten, M Moreno-Gon, C Bone, A Martens, F Bernuzzi, T Ludwig, C Hellmich, K Hiller, SA Rushworth, N Beraza
    Cellular and Molecular Gastroenterology and Hepatology, 2021;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  27. Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway
    Authors: N Majumder, M Velayutham, D Bitounis, VK Kodali, MH Hasan Mazu, J Amedro, VV Khramtsov, A Erdely, T Nurkiewicz, P Demokritou, EE Kelley, S Hussain
    Redox Biology, 2021;47(0):102161.
    Species: Mouse
    Sample Types: BALF
  28. Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    Authors: S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, C Peterson, A Zimmerman, MA Mandell, SD Jett, E Bigio, C Geula, N Mellios, JP Weick, GA Rosenberg, E Latz, MT Heneka, K Bhaskar
    Cell Reports, 2021;36(12):109720.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  29. PB1-F2 amyloid-like fibers correlate with pro-inflammatory signaling and respiratory distress in influenza-infected mice
    Authors: C Chevalier, O Leymarie, L Sedano, B Da Costa, CA Richard, P Maisonnass, M Réfregiers, F Jamme, R Le Goffic
    The Journal of Biological Chemistry, 2021;0(0):100885.
    Species: Mouse
    Sample Types: BALF
  30. Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
    Authors: N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain
    Redox Biology, 2021;46(0):102092.
    Species: Mouse
    Sample Types: BALF
  31. Acute Lung Injury in Cholinergic-Deficient Mice Supports Anti-Inflammatory Role of alpha7 Nicotinic Acetylcholine Receptor
    Authors: NM Pinheiro, R Banzato, I Tibério, MAM Prado, VF Prado, AK Hamouda, CM Prado
    International Journal of Molecular Sciences, 2021;22(14):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  32. Sambucus nigra: A traditional medicine effective in reducing inflammation in mice
    Authors: JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão
    Journal of ethnopharmacology, 2021;283(0):114736.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  33. Peroxiredoxin AhpC1 protects Pseudomonas aeruginosa against the inflammatory oxidative burst and confers virulence
    Authors: LS Rocha, BPD Silva, TML Correia, RPD Silva, DA Meireles, R Pereira, LES Netto, FC Meotti, RF Queiroz
    Redox Biology, 2021;46(0):102075.
    Species: Mouse
    Sample Types: Serum
  34. Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs
    Authors: L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin
    Journal of Immunology Research, 2021;2021(0):9957451.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS)
    Authors: D Shah, P Das, S Acharya, B Agarwal, DJ Christense, SM Robertson, V Bhandari
    International Journal of Molecular Sciences, 2021;22(5):.
    Species: Mouse
    Sample Types: BALF
  36. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
    Authors: V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea
    Biomedicines, 2021;9(6):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation
    Authors: S Nizami, V Millar, K Arunasalam, T Zarganes-T, D Brough, G Tresadern, PE Brennan, JB Davis, D Ebner, E Di Daniel
    Scientific Reports, 2021;11(1):15319.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  38. A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS
    Authors: M Najibi, HH Honwad, JA Moreau, SM Becker, JE Irazoqui
    Autophagy, 2021;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  39. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
    Authors: C Xu, S Sun, T Johnson, R Qi, S Zhang, J Zhang, K Yang
    Cell Reports, 2021;35(11):109235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  40. Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2
    Authors: WJ Melvin, CO Audu, FM Davis, SB Sharma, A Joshi, A DenDekker, S Wolf, E Barrett, K Mangum, X Zhou, M Bame, A Ruan, A Obi, SL Kunkel, BB Moore, KA Gallagher
    Proceedings of the National Academy of Sciences of the United States of America, 2021;118(38):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model
    Authors: M Hafner, S Paukner, WW Wicha, B Hrva?i?, M Cedilak, I Faraho, SP Gelone
    PLoS ONE, 2021;16(9):e0237659.
    Species: Mouse
    Sample Types: Tissue Homogenates
  42. Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice
    Authors: JP Martins, LC Silva, MS Nunes, G Rübensam, JR Oliveira, RBM Silva, MM Campos
    Nutrients, 2021;13(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  43. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity
    Authors: G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello
    Cell Reports, 2021;35(1):108955.
    Species: Mouse
    Sample Types: Tissue Homogenates
  44. Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages
    Authors: S Elhag, C Stremmel, A Zehrer, J Plocke, R Hennel, M Keuper, C Knabe, J Winterhalt, V Gölling, L Tomas, T Weinberger, M Fischer, L Liu, F Wagner, M Lorenz, K Stark, H Häcker, M Schmidt-Su, U Völker, M Jastroch, K Lauber, T Straub, B Walzog, E Hammer, C Schulz
    Cells, 2021;10(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  45. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
    Authors: R Peruzzo, S Corrà, R Costa, M Brischigli, T Varanita, L Biasutto, C Rampazzo, D Ghezzi, L Leanza, M Zoratti, M Zeviani, C De Pittà, C Viscomi, R Costa, I Szabò
    Nature Communications, 2021;12(1):2103.
    Species: Mouse
    Sample Types: Plasma
  46. Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
    Authors: S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, K Hamilton, A Badr, K Daily, C Carafice, D Baetzhold, X Zhang, T Li, H Wen, MA Gavrilin, H Haffez, S Soror, AO Amer
    Scientific Reports, 2021;11(1):855.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  47. Hepatocytes are resistant to cell death from canonical and non-canonical inflammasome-activated pyroptosis
    Authors: P Sun, J Zhong, H Liao, P Loughran, J Mulla, G Fu, D Tang, J Fan, TR Billiar, W Gao, MJ Scott
    Cellular and Molecular Gastroenterology and Hepatology, 2021;0(0):.
    Species: Mouse
    Sample Types: Plasma
  48. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus
    Authors: A Amend, N Wickli, AL Schäfer, DTL Sprenger, RA Manz, RE Voll, N Chevalier
    International Journal of Molecular Sciences, 2021;22(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  49. IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells
    Authors: J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar
    Elife, 2021;10(0):.
    Species: Mouse
    Sample Types: Serum
  50. Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
    Authors: N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim
    Journal of Immunology Research, 2021;2021(0):9944880.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)
    Authors: CK Lin, TH Huang, CT Yang, CS Shi
    PLoS ONE, 2021;16(3):e0248959.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. Parabens disrupt non-canonical inflammasome activation
    Authors: H Ahn, H Lee, G Lee, J Park, HW Sung, E Lee, GS Lee
    International immunopharmacology, 2021;101(0):108196.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  53. NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
    Authors: FRC Costa, JA Leite, DM Rassi, JF da Silva, J Elias-Oliv, JB Guimarães, MC Foss-Freit, NOS Câmara, A Pontillo, RC Tostes, JS Silva, D Carlos
    Cell Reports, 2021;35(8):109176.
    Species: Mouse
    Sample Types: Tissue Homogenates
  54. Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
    Authors: H Shokirova, T Inomata, T Saitoh, J Zhu, K Fujio, Y Okumura, A Yanagawa, K Fujimoto, J Sung, A Eguchi, M Miura, K Nagino, K Hirosawa, M Kuwahara, Y Akasaki, H Nagase, A Murakami
    Scientific Reports, 2021;11(1):8647.
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms
    Authors: PS Vieceli, PJ Lima Juiz, PS Sales Laur, RD Couto, TC Barbosa To, IM Ribeiro, MB Pereira So, CF Villarreal
    Journal of ethnopharmacology, 2021;0(0):113986.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  56. Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation
    Authors: S Omori, M Tsugita, Y Hoshikawa, M Morita, F Ito, SI Yamaguchi, Q Xie, O Noyori, T Yamaguchi, A Takada, T Saitoh, S Toyokuni, H Akiba, S Nagata, K Kinoshita, M Nakayama
    Cell Reports, 2021;34(6):108734.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes
    Authors: LAD Queiroz, JB Assis, JPT Guimarães, ESA Sousa, AC Milhomem, KKS Sunahara, A Sá-Nunes, JO Martins
    Mediators of Inflammation, 2021;2021(0):9940009.
    Species: Mouse
    Sample Types: Tissue Homogenates
  58. Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
    Cell Reports, 2021;34(10):108826.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  59. Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
    Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
    Journal of Neuroinflammation, 2021;18(1):60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  60. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway
    Authors: YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai
    Acta pharmacologica Sinica, 2021;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  61. Pertactin contributes to shedding and transmission of Bordetella bronchiseptica
    Authors: L Ma, KK Dewan, DL Taylor-Mul, SM Wagner, B Linz, I Rivera, Y Su, AD Caulfield, U Blas-Macha, ET Harvill
    PloS Pathogens, 2021;17(8):e1009735.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo
    Authors: HL Wang, FQ Chen, LJ Wu
    International immunopharmacology, 2021;103(0):107842.
    Species: Mouse
    Sample Types: BALF
  63. Itaconate confers tolerance to late NLRP3 inflammasome activation
    Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
    Cell Reports, 2021;34(10):108756.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  64. Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages
    Authors: PJ Chiu, J Rathod, YP Hong, PJ Tsai, YP Hung, WC Ko, JW Chen, D Paredes-Sa, IH Huang
    Anaerobe, 2021;70(0):102381.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  65. Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation
    Authors: SM Borghi, SKD Bussulo, FA Pinho-Ribe, V Fattori, TT Carvalho, FS Rasquel-Ol, TH Zaninelli, CR Ferraz, AMB Casella, FQ Cunha, TM Cunha, R Casagrande, WA Verri
    Frontiers in Pharmacology, 2021;12(0):734091.
    Species: Mouse
    Sample Types: Tissue Homogenates
  66. Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
    Authors: MG Dorrington, CJ Bradfield, JB Lack, B Lin, JJ Liang, T Starr, O Ernst, JL Gross, J Sun, AH Miller, O Steele-Mor, IDC Fraser
    PloS Pathogens, 2021;17(3):e1009395.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia
    Authors: J Lücht, N Rolfs, SJ Wowro, F Berger, KRL Schmitt, G Tong
    Mediators of Inflammation, 2021;2021(0):8906561.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  68. Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis
    Authors: JS Ha, HR Choi, IS Kim, EA Kim, SW Cho, SJ Yang
    International Journal of Molecular Sciences, 2021;22(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  69. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
    Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
    Nature Communications, 2021;12(1):6637.
    Species: Mouse
    Sample Types: Tissue Homogenates
  70. Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis
    Authors: D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi
    Nutrients, 2021;13(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  71. Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572
    Authors: P Diez-Echav, I Martín-Cab, J Garrido-Me, S Langa, T Vezza, JM Landete, L Hidalgo-Ga, F Algieri, MJ Mayer, A Narbad, A García-Laf, M Medina, A Rodríguez-, ME Rodríguez-, J Gálvez, JL Arqués
    Nutrients, 2021;13(6):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  72. Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice
    Authors: X Xiao, D Liu, S Chen, X Li, M Ge, W Huang
    Cellular Signalling, 2021;0(0):109966.
    Species: Mouse
    Sample Types: Tissue Homogenates
  73. Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
    Authors: J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao
    PLoS ONE, 2021;16(5):e0251677.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  74. &alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain
    Authors: FR Pinheiro-N, EM Lopes, BT Acha, LDS Gomes, WA Dias, ACD Reis Filho, BS Leal, DCDN Rodrigues, JDN Silva, D Dittz, PMP Ferreira, FRC Almeida
    Toxicology and Applied Pharmacology, 2021;418(0):115497.
    Species: Mouse
    Sample Types: Serum
  75. Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund's adjuvant-induced mouse model
    Authors: DJ Su, LF Li, SY Wang, Q Yang, YJ Wu, MG Zhao, L Yang
    Molecular pain, 2021;17(0):1744806921990.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  76. NLRP6-associated host microbiota composition impacts in the intestinal barrier to systemic dissemination of Brucella abortus
    Authors: M Rungue, V Melo, D Martins, PC Campos, G Leles, I Galvão, V Mendes, M Aganetti, Á Pedersen, NRG Assis, R Santos, GD Cassali, ALB Godard, FS Martins, SC Oliveira, AT Vieira
    PloS Neglected Tropical Diseases, 2021;15(2):e0009171.
    Species: Mouse
    Sample Types: Tissue Homogenates
  77. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
    Authors: TP Fidler, C Xue, M Yalcinkaya, B Hardaway, S Abramowicz, T Xiao, W Liu, DG Thomas, MA Hajebrahim, J Pircher, C Silvestre-, AG Kotini, LL Luchsinger, Y Wei, M Westerterp, HW Snoeck, EP Papapetrou, C Schulz, S Massberg, O Soehnlein, B Ebert, RL Levine, MP Reilly, P Libby, N Wang, AR Tall
    Nature, 2021;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  78. Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
    Authors: JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy
    Nature Communications, 2021;12(1):1460.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  79. Discovery and characterization of small molecule inhibitors of NLRP3 and NLRC4 inflammasomes
    Authors: M Sebastian-, H Wu, M Al Rahim, R Sanchez, K Kumar, RJ De Vita, GM Pasinetti
    The Journal of Biological Chemistry, 2021;0(0):100597.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  80. 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice
    Authors: LA Rojas-Coló, PK Dash, FA Morales-Ví, M Lebrón-Dáv, PA Ferchmin, JB Redell, G Maldonado-, WI Vélez-Torr
    Journal of Neuroinflammation, 2021;18(1):95.
    Species: Mouse
    Sample Types: Plasma
  81. Dual chemotherapy with benznidazole at suboptimal dose plus curcumin nanoparticles mitigates Trypanosoma cruzi-elicited chronic cardiomyopathy
    Authors: M Hernández, S Wicz, E Pérez Caba, MH Santamaría, RS Corral
    Parasitol Int, 2020;81(0):102248.
    Species: Mouse
    Sample Types: Tissue Homogenates
  82. Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract
    Authors: MC Gestal, U Blas-Macha, HM Johnson, LN Rubin, KK Dewan, C Bryant, M Tiemeyer, ET Harvill
    Microorganisms, 2020;8(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  83. Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis
    Authors: FM de Jesus O, CF Gonçalves-, IMM de Moraes, PA Reis, VN Rocha, PT Bozza, AR Silva, HC de Castro
    Mediators Inflamm, 2020;2020(0):1839762.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  84. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis
    Authors: P Mandal, AL McCormick, ES Mocarski
    Viruses, 2020;12(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  85. Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors
    Authors: N Hijaze, M Ledersnaid, E Simanovich, S Kassem, MA Rahat
    J Leukoc Biol, 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
    Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
    J Neuroinflammation, 2020;17(1):324.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  87. The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model
    Authors: K Sato, A Tobo, C Mogi, M Tobo, N Yamane, M Tosaka, H Tomura, DS Im, F Okajima
    Sci Rep, 2020;10(1):17193.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  88. Different experimental multiple trauma models induce comparable inflammation and organ injury
    Authors: B Relja, B Yang, K Bundkirche, B Xu, K Köhler, C Neunaber
    Sci Rep, 2020;10(1):20185.
    Species: Mouse
    Sample Types: Plasma
  89. Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation
    Authors: W Fonseca, CA Malinczak, CF Schuler, SKK Best, AJ Rasky, SB Morris, TX Cui, AP Popova, NW Lukacs
    Mucosal Immunol, 2020;0(0):.
    Species: Mouse
    Sample Types: BALF
  90. Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice
    Authors: JM Kline, E Arriaga-Go, T Yangdon, B Boo, J Landry, M Saldías-Mo, N Neamonitak, H Mengistu, S Silverio, H Zacheis, D Pasha, T Martinov, BT Fife, D Chatterjea
    PLoS ONE, 2020;15(10):e0241218.
    Species: Mouse
    Sample Types: Cell Lysates
  91. TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection
    Authors: AL Aldrich, CE Heim, W Shi, RW Fallet, B Duan, T Kielian
    J Neuroinflammation, 2020;17(1):114.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD
    Authors: KM Han, RJ Kang, H Jeon, HJ Lee, JS Lee, H Park, S Gak Jeon, K Suk, J Seo, HS Hoe
    Cells, 2020;9(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  93. Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation
    Authors: Y Guo, D Gu, T Huang, L Cao, X Zhu, Y Zhou, K Wang, X Kang, C Meng, X Jiao, Z Pan
    BMC Microbiol., 2020;20(1):226.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  94. Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction
    Authors: N Gebert, CW Cheng, JM Kirkpatric, D Di Fraia, J Yun, P Schädel, S Pace, GB Garside, O Werz, KL Rudolph, H Jasper, ÖH Yilmaz, A Ori
    Cell Rep, 2020;31(4):107565.
    Species: Mouse
    Sample Types: Tissue Homogenates
  95. I&kappaB? controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene
    Authors: J Kim, H Ahn, S Yu, JH Ahn, HJ Ko, MN Kweon, EJ Hong, BS An, E Lee, GS Lee
    Cytokine, 2020;127(0):154983.
    Species: Mouse
    Sample Types: Serum
  96. Detrimental Role of Nerve Injury-Induced Protein 1 in Myeloid Cells under Intestinal Inflammatory Conditions
    Authors: HJ Jung, JH Kang, S Pak, K Lee, JK Seong, SH Oh
    Int J Mol Sci, 2020;21(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  97. Maternal high fat diet consumption reduces liver alpha7 nicotinic cholinergic receptor expression and impairs insulin signalling in the offspring
    Authors: SO Costa, CM Souza, PG Lanza, JO Sartori, LM Ignacio-So, T Candreva, HG Rodrigues, AS Torsoni, M Milanski, MA Torsoni
    Sci Rep, 2020;10(1):48.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy following Ischemic Brain Injury
    Authors: C Espinosa-G, F Atif, S Yousuf, I Sayeed, GN Neigh, DG Stein
    Int J Mol Sci, 2020;21(11):.
    Species: Mouse
    Sample Types: Cell Supernatants
  99. Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    Authors: SB Kovacs, C Oh, VI Maltez, BD McGlaughon, A Verma, EA Miao, Y Aachoui
    Cell Rep, 2020;32(4):107967.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  100. TNF-&alpha Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury
    Authors: M Kim, K Jung, Y Ko, IS Kim, K Hwang, JH Jang, JE Shin, KI Park
    Cells, 2020;9(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  101. The C5a/C5aR2 axis promotes renal inflammation and tissue damage
    Authors: T Zhang, KY Wu, N Ma, LL Wei, M Garstka, W Zhou, K Li
    JCI Insight, 2020;5(7):.
    Species: Mouse
    Sample Types: Tissue Lysates
  102. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020;11(1):2212.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice
    Authors: MS Ko, JY Yun, IJ Baek, JE Jang, JJ Hwang, SE Lee, SH Heo, DA Bader, CH Lee, J Han, JS Moon, JM Lee, EG Hong, IK Lee, SW Kim, JY Park, SM Hartig, UJ Kang, DD Moore, EH Koh, KU Lee
    Autophagy, 2020;0(0):1-17.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides
    Authors: HC Lin, JY Lin
    Evid Based Complement Alternat Med, 2020;2020(0):9450246.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  105. The Role of ST2 Receptor in the Regulation of Brucella abortus Oral Infection
    Authors: R Santos, PC Campos, M Rungue, V Rocha, D Santos, V Mendes, FV Marinho, F Martins, MF Ricci, DCD Reis, GD Cassali, JC Alves-Filh, AT Vieira, SC Oliveira
    Pathogens, 2020;9(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
    Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
    Nat Commun, 2020;11(1):3624.
    Species: Human
    Sample Types: Cell Culture Supernates
  107. Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis
    Authors: H Liu, X Yang, K Tang, T Ye, C Duan, P Lv, L Yan, X Wu, Z Chen, J Liu, Y Deng, G Zeng, J Xing, Z Ye, H Xu
    Theranostics, 2020;10(16):7319-7334.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  108. Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization
    Authors: P De Cicco, M Maisto, GC Tenore, A Ianaro
    Nutrients, 2020;12(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  109. Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity
    Authors: H Ahn, GS Lee
    Sci Rep, 2020;10(1):19091.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  110. Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection
    Authors: TM Tucey, J Verma, FAB Olivier, TL Lo, AAB Robertson, T Naderer, A Traven
    PLoS Pathog., 2020;16(8):e1008695.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  111. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  112. Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice
    Authors: YS Lee, D Min, SY Park, J Lee, H Bae
    BMC Complement Med Ther, 2020;20(1):270.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  113. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
    Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
    J Neuroinflammation, 2020;17(1):299.
  114. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020;8(8):.
    Species: Mouse
    Sample Types: Cell Lysates
  115. A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
    Authors: S Narendran, F Pereira, P Yerramothu, I Apicella, SB Wang, A Varshney, KL Baker, KM Marion, M Ambati, VL Ambati, K Ambati, SR Sadda, BD Gelfand, J Ambati
    Invest. Ophthalmol. Vis. Sci., 2020;61(10):4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  116. Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer's disease mouse model
    Authors: RC Ng, M Jian, OK Ma, M Bunting, JS Kwan, GJ Zhou, K Senthilkum, A Iyaswamy, PK Chan, M Li, KM Leung, SS Kumar Dura, KS Lam, LW Chu, R Festenstei, SK Chung, KH Chan
    Mol. Psychiatry, 2020;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  117. Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
    Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
    Cell Rep, 2020;32(2):107906.
    Species: Mouse
    Sample Types: Serum
  118. &beta-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
    Authors: LL Friker, H Scheiblich, IV Hochheiser, R Brinkschul, D Riedel, E Latz, M Geyer, MT Heneka
    Cell Rep, 2020;30(11):3743-3754.e6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  119. Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine production in macrophages and associated experimental hepatitis
    Authors: J Schwaderer, TS Phan, A Glöckner, J Delp, M Leist, T Brunner, ME Delgado
    Cell Death Dis, 2020;11(2):154.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  120. Interleukin-1 Receptor-Induced Nitric Oxide Production in the Pancreas Controls Hyperglycemia Caused by Scorpion Envenomation
    Authors: MB Reis, J Elias-Oliv, MR Pastore, SG Ramos, LG Gardinassi, LH Faccioli
    Toxins (Basel), 2020;12(3):.
    Species: Mouse
    Sample Types: Serum
  121. Nose-Only Water-Pipe Smoke Exposure in Mice Elicits Renal Histopathological Alterations, Inflammation, Oxidative Stress, DNA Damage, and Apoptosis
    Authors: A Nemmar, S Beegam, P Yuvaraju, J Yasin, BH Ali, E Adeghate
    Front Physiol, 2020;11(0):46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  122. STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression
    Authors: JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell
    Nat Commun, 2020;11(1):3816.
    Species: Mouse
    Sample Types: Cell Lysate
  123. Angiotensin II induces RAW264.7 macrophage polarization to the M1?type through the connexin 43/NF?&kappaB pathway
    Authors: L Wu, K Chen, J Xiao, J Xin, L Zhang, X Li, L Li, J Si, L Wang, K Ma
    Mol Med Rep, 2020;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  124. GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation
    Authors: T Castro-Dop, A Fleming, TW Dennison, JR Ferdinand, K Harcourt, BJ Stewart, Z Cader, ZK Tuong, C Jing, LSC Lok, RJ Mathews, A Portet, A Kaser, S Clare, MR Clatworthy
    Cell Rep, 2020;32(1):107857.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
    Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
    Cytokine, 2020;137(0):155334.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  126. Mitochondrial dysfunction caused by outer membrane vesicles from Gram-negative bacteria activates intrinsic apoptosis and inflammation
    Authors: P Deo, SH Chow, ML Han, M Speir, C Huang, RB Schittenhe, S Dhital, J Emery, J Li, BT Kile, JE Vince, KE Lawlor, T Naderer
    Nat Microbiol, 2020;0(0):.
    Species: Mouse
    Sample Types: Serum
  127. Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling
    Authors: A Fajstova, N Galanova, S Coufal, J Malkova, M Kostovcik, M Cermakova, H Pelantova, M Kuzma, B Sediva, T Hudcovic, T Hrncir, H Tlaskalova, M Kverka, K Kostovciko
    Cells, 2020;9(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  128. Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917
    Authors: O Dusek, A Fajstova, A Klimova, P Svozilkova, T Hrncir, M Kverka, S Coufal, J Slemin, H Tlaskalova, JV Forrester, J Heissigero
    Cells, 2020;10(1):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  129. Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
    Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
    Cell Rep, 2020;33(2):108247.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  130. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
    Authors: X Li, M Zhang, X Huang, W Liang, G Li, X Lu, Y Li, H Pan, L Shi, H Zhu, L Qian, B Shan, J Yuan
    Nature Communications, 2020;11(1):6364.
    Species: Mouse
    Sample Types: Serum
  131. Unique maternal immune and functional microbial profiles during prenatal stress
    Authors: AM Antonson, MV Evans, JD Galley, HJ Chen, TA Rajasekera, SM Lammers, VL Hale, MT Bailey, TL Gur
    Sci Rep, 2020;10(1):20288.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. Waterpipe Tobacco Smoke Inhalation Triggers Thrombogenicity, Cardiac Inflammation and Oxidative Stress in Mice: Effects of Flavouring
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, NE Zaaba, J Yasin, BH Ali
    Int J Mol Sci, 2020;21(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  133. Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function
    Authors: SS Chiang, LS Chen, CY Chu
    Chemosphere, 2020;267(0):129267.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  134. Antitumor and Anti-Metastatic Effects of Citral-Loaded Nanostructured Lipid Carrier in 4T1-Induced Breast Cancer Mouse Model
    Authors: N Nordin, SK Yeap, HS Rahman, NR Zamberi, NE Mohamad, N Abu, MJ Masarudin, R Abdullah, NB Alitheen
    Molecules, 2020;25(11):.
    Species: Mouse
    Sample Types: Serum
  135. TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection
    Authors: DO Kim, JE Byun, WS Kim, MJ Kim, JH Choi, H Kim, E Choi, TD Kim, SR Yoon, JY Noh, YJ Park, J Lee, HJ Cho, HG Lee, SH Min, I Choi, H Jung
    International Journal of Molecular Sciences, 2020;21(24):.
    Species: Mouse
    Sample Types: Serum
  136. TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
    Authors: T Sakaguchi, R Okumura, C Ono, D Okuzaki, T Kawai, Y Okochi, N Tanimura, M Murakami, H Kayama, E Umemoto, H Kioka, T Ohtani, Y Sakata, K Miyake, Y Okamura, Y Baba, K Takeda
    Cell Rep, 2020;31(10):107755.
    Species: Mouse
    Sample Types: Serum
  137. (E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
    Authors: P Silva, M de Almeida, J Silva, S Albino, R Espírito-S, M Lima, C Villarreal, R Moura, V Santos
    Int J Mol Sci, 2020;21(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression
    Authors: JE Rexach, D Polioudaki, A Yin, V Swarup, TS Chang, T Nguyen, A Sarkar, L Chen, J Huang, LC Lin, W Seeley, JQ Trojanowsk, D Malhotra, DH Geschwind
    Cell Rep, 2020;33(7):108398.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  139. The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta
    Authors: J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock
    EBioMedicine, 2020;60(0):102984.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
    Authors: Y Duan, L Zhang, D Angosto-Ba, P Pelegrín, G Núñez, Y He
    Cell Rep, 2020;33(7):108405.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
    Authors: H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang
    Cell Rep, 2020;30(3):793-806.e6.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. SIRT1 Alleviates LPS-Induced IL-1&beta Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts
    Authors: S Park, J Shin, J Bae, D Han, SR Park, J Shin, SK Lee, HW Park
    Cells, 2020;9(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  143. Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus
    Authors: JS Ye, L Chen, YY Lu, SQ Lei, M Peng, ZY Xia
    Oxid Med Cell Longev, 2019;2019(0):8639618.
    Species: Mouse
    Sample Types: Tissue Secretion
  144. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
    Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
    Cell Rep, 2019;27(3):750-761.e7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  145. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  146. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019;15(4):e1007689.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice
    Authors: M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow
    J Neuroinflammation, 2019;16(1):69.
  148. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
    Authors: L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Gu, EV LeBlanc, CS Nation, R Hui, A Hutchinson, C Collins, S Chatterjee, R Trilles, JL Xie, DJ Krysan, S Lindquist, JA Porco, U Tatu, LE Brown, J Pizarro, LE Cowen
    Nat Commun, 2019;10(1):402.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  149. HSP70 is a negative regulator of NLRP3 inflammasome activation
    Authors: P Martine, A Chevriaux, V Derangère, L Apetoh, C Garrido, F Ghiringhel, C Rébé
    Cell Death Dis, 2019;10(4):256.
    Species: Mouse
    Sample Types: Lavage Fluid
  150. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
    Authors: Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan
    J Neuroinflammation, 2019;16(1):62.
    Species: Mouse
    Sample Types: Tissue Homogenates
  151. Caveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis
    Authors: X Lin, M Barravecch, R Matthew Ko, P Sime, DA Dean
    Sci Rep, 2019;9(1):19643.
  152. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
    Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
    Sci Rep, 2019;9(1):4034.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile
    Authors: P Mamareli, F Kruse, C Friedrich, N Smit, T Strowig, T Sparwasser, M Lochner
    Eur. J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  154. The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices
    Authors: MJR Ruigrok, J Tomar, HW Frijlink, BN Melgert, WLJ Hinrichs, P Olinga
    Sci Rep, 2019;9(1):16239.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  155. Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring
    Authors: RR E-Lacerda, CJ Teixeira, S Bordin, E Antunes, GF Anhê
    Nutrients, 2019;11(12):.
    Species: Mouse
    Sample Types: BALF
  156. Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
    Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
    Cytokine, 2019;119(0):71-80.
    Species: Mouse
    Sample Types: Tissue Homogenates
  157. Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway
    Authors: SZA Shah, D Zhao, G Taglialate, T Hussain, H Dong, N Sabir, MH Mangi, W Wu, M Lai, X Zhang, Y Duan, L Wang, X Zhou, L Yang
    Int J Mol Sci, 2019;20(5):.
    Species: Hamster
    Sample Types: Tissue Homogenates
  158. Interleukin-37 monomer is the active form for reducing innate immunity
    Authors: EZ Eisenmesse, A Gottschlic, JS Redzic, N Paukovich, JC Nix, T Azam, L Zhang, R Zhao, JS Kieft, E The, X Meng, CA Dinarello
    Proc. Natl. Acad. Sci. U.S.A., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  159. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome
    Authors: RVH de Carvalh, WA Andrade, DS Lima-Junio, M Dilucca, CV de Oliveir, K Wang, PM Nogueira, JN Rugani, RP Soares, SM Beverley, F Shao, DS Zamboni
    Cell Rep, 2019;26(2):429-437.e5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  160. Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
    Front Physiol, 2019;10(0):53.
    Species: Mouse
    Sample Types: Tissue Homogenates
  161. Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation
    Authors: K Ishimaru, K Yoshioka, K Kano, M Kurano, D Saigusa, J Aoki, Y Yatomi, N Takuwa, Y Okamoto, RL Proia, Y Takuwa
    Sci Rep, 2019;9(1):18329.
    Species: Mouse
    Sample Types: Plasma
  162. Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
    Authors: JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree
    Cell Rep, 2019;28(1):218-230.e7.
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  163. The three cytokines IL-1?, IL-18, and IL-1? share related but distinct secretory routes
    Authors: VS Tapia, MJD Daniels, P Palazón-Ri, M Dewhurst, NM Luheshi, J Rivers-Aut, J Green, E Redondo-Ca, P Kaldis, G Lopez-Cast, D Brough
    J. Biol. Chem., 2019;294(21):8325-8335.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  164. A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy
    Authors: M Torvell, DW Hampton, P Connick, AMJ MacLullich, C Cunningham, S Chandran
    Alzheimers Dement (N Y), 2019;5(0):579-591.
    Species: Mouse
    Sample Types: Serum
  165. Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
    Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
    MBio, 2019;10(5):.
    Species: Mouse
    Sample Types: BALF
  166. Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice
    Authors: DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira
    J. Nutr. Biochem., 2019;72(0):108208.
    Species: Mouse
    Sample Types: Tissue Homogenates
  167. Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
    Authors: HE Lee, G Yang, YB Park, HC Kang, YY Cho, HS Lee, JY Lee
    Molecules, 2019;24(11):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  168. IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
    Authors: AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, MM Abhyankar, CA Cowardin, JZ Ma, P Pramoonjag, SD Turner, AP Liou, EL Buonomo, WA Petri
    Nat Commun, 2019;10(1):2712.
    Species: Mouse
    Sample Types: Tissue Homogenates
  169. Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet
    Authors: H Lee, TH Tu, BS Park, S Yang, JG Kim
    Int J Mol Sci, 2019;20(22):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  170. PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
    Authors: L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie
    PLoS ONE, 2019;14(9):e0222753.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  171. Context-specific switch from anti- to pro-epileptogenic function of the P2Y1 receptor in experimental epilepsy
    Authors: M Alves, L De Diego G, G Conte, EM Jimenez-Ma, B D'Orsi, A Sanz-Rodri, JH Prehn, DC Henshall, T Engel
    J. Neurosci., 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  172. Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages
    Authors: G Kalugotla, L He, KJ Weber, S Daemen, A Reller, B Razani, JD Schilling
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  173. Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice
    Authors: B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues
    Sci Rep, 2019;9(1):9119.
    Species: Mouse
    Sample Types: Tissue Homogenates
  174. Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection
    Authors: I Santecchia, F Vernel-Pau, O Rasid, J Quintin, M Gomes-Sole, IG Boneca, C Werts
    PLoS Pathog., 2019;15(5):e1007811.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  175. In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
    Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
    EBioMedicine, 2019;0(0):.
    Species: Mouse
    Sample Types: Plasma
  176. In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
    Authors: N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli
    Mol Ther Methods Clin Dev, 2019;13(0):67-76.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  177. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  178. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling
    Authors: C McWherter, YJ Choi, RL Serrano, SK Mahata, R Terkeltaub, R Liu-Bryan
    Arthritis Res. Ther., 2018;20(1):204.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  179. Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
    Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
    Diabetologia, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  180. Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
    Authors: T Karasawa, A Kawashima, F Usui-Kawan, S Watanabe, H Kimura, R Kamata, K Shirasuna, Y Koyama, A Sato-Tomit, T Matsuzaka, H Tomoda, SY Park, N Shibayama, H Shimano, T Kasahara, M Takahashi
    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  181. A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
    Authors: C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar
    Autophagy, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  182. FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation
    Authors: Z Li, J Zhao, S Zhang, SA Weinman
    Cell Death Discov, 2018;4(0):16.
    Species: Mouse
    Sample Types: Serum
  183. Jugular arginine infusion relieves lipopolysaccharide-triggered inflammatory stress and improves immunity status of lactating dairy cows
    Authors: FF Zhao, TY Wu, HR Wang, LY Ding, G Ahmed, HW Li, W Tian, YZ Shen
    J. Dairy Sci., 2018;0(0):.
    Species: Bovine
    Sample Types: Serum
  184. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
    Authors: F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti
    Glia, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  185. A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
    Authors: B Koch, AA Barugahare, TL Lo, C Huang, RB Schittenhe, DR Powell, TH Beilharz, A Traven
    Cell Rep, 2018;25(8):2244-2258.e7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  186. Activation of M1 macrophages play a critical role in the initiation of acute lung injury
    Authors: HL Lu, XY Huang, YF Luo, WP Tan, PF Chen, YB Guo
    Biosci. Rep., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  187. NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
    Authors: SK Matta, K Patten, Q Wang, BH Kim, JD MacMicking, LD Sibley
    MBio, 2018;9(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  188. Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia
    Authors: S Kim, Y Joe, SU Park, SO Jeong, JK Kim, SH Park, HO Pae, YJ Surh, J Shin, HT Chung
    J. Leukoc. Biol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  189. Choline transport links macrophage phospholipid metabolism and inflammation
    Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  190. Analogous corticosteroids, 9A and EK100, derived from solid-state-cultured mycelium of Antrodia camphorata inhibit proinflammatory cytokine expression in macrophages
    Authors: ST Kao, YH Kuo, SD Wang, HJ Hong, LJ Lin
    Cytokine, 2018;108(0):136-144.
    Species: Mouse
    Sample Types: BALF
  191. Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation
    Authors: SB Kwak, S Koppula, EJ In, X Sun, YK Kim, MK Kim, KH Lee, TB Kang
    Mediators Inflamm., 2018;2018(0):6054069.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  192. Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation
    Authors: JC d'Avila, LD Siqueira, A Mazeraud, EP Azevedo, D Foguel, HC Castro-Far, T Sharshar, F Chrétien, FA Bozza
    J Neuroinflammation, 2018;15(1):28.
    Species: Mouse
    Sample Types: Tissue Homogenates
  193. MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice
    Authors: AP Perera, R Fernando, T Shinde, R Gundamaraj, B Southam, SS Sohal, AAB Robertson, K Schroder, D Kunde, R Eri
    Sci Rep, 2018;8(1):8618.
    Species: Mouse
    Sample Types: Tissue Homogenates
  194. HMGB1/IL-1? complexes in plasma microvesicles modulate immune responses to burn injury
    Authors: LG Coleman, R Maile, SW Jones, BA Cairns, FT Crews
    PLoS ONE, 2018;13(3):e0195335.
    Species: Mouse
    Sample Types: Plasma
  195. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
    Nat Commun, 2018;9(1):242.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  196. Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation
    Authors: K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao
    Cell. Physiol. Biochem., 2018;47(5):2170-2184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  197. Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria
    Authors: P Strangward, MJ Haley, MG Albornoz, J Barrington, T Shaw, R Dookie, L Zeef, SM Baker, E Winter, TC Tzeng, DT Golenbock, SM Cruickshan, SM Allan, A Craig, FY Liew, D Brough, KN Couper
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  198. Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway
    Authors: L Subedi, SH Baek, SY Kim
    Oxid Med Cell Longev, 2018;2018(0):8092713.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  199. Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
    Authors: M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld
    PLoS ONE, 2018;13(8):e0200615.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  200. Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
    Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
    Oncotarget, 2018;9(55):30635-30648.
    Species: Mouse
    Sample Types: BALF
  201. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy
    Authors: F Sato-Kanek, X Wang, S Yao, T Hosoya, FS Lao, K Messer, M Pu, NM Shukla, HB Cottam, M Chan, DA Carson, M Corr, T Hayashi
    Biomed Res Int, 2018;2018(0):8091283.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  202. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1? Activation
    Authors: JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, S Vijayaraj, LM Lindqvist, P Bouillet, MA Rizzacasa, SM Man, J Silke, SL Masters, G Lessene, DCS Huang, DHD Gray, BT Kile, F Shao, KE Lawlor
    Cell Rep, 2018;25(9):2339-2353.e4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  203. Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
    Authors: CW Hui, X Song, F Ma, X Shen, K Herrup
    J Neuroinflammation, 2018;15(1):308.
    Species: Mouse
    Sample Types: Tissue Homogenates
  204. Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine
    Authors: PK Shukla, AS Meena, V Rao, RG Rao, L Balazs, R Rao
    Sci Rep, 2018;8(1):16241.
  205. Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis
    Authors: IM Medeiros-d, CF Gonçalves-, ARM Kurz, FMJ Oliveira, VHP de Abreu, RC Torres, VF Carvalho, V Estato, PT Bozza, M Sperandio, HC de Castro-, AR Silva
    Oxid Med Cell Longev, 2018;2018(0):6053492.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  206. Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
    Authors: Y Fujita, A Khateb, Y Li, R Tinoco, T Zhang, H Bar-Yoseph, MA Tam, Y Chowers, E Sabo, S Gerassy-Va, E Starosvets, B James, K Brown, SS Shen-Orr, LM Bradley, PA Tessier, ZA Ronai
    Cell Rep, 2018;24(12):3296-3311.e6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  207. Enzymatic Activity Is Not Required for Phospholipase D Mediated TNF-? Regulation and Myocardial Healing
    Authors: M Klier, S Gorressen, MA Urbahn, D Barbosa, M Ouwens, JW Fischer, M Elvers
    Front Physiol, 2018;9(0):1698.
    Species: Mouse
    Sample Types: Plasma
  208. Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
    Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
    J. Nutr. Biochem., 2018;62(0):28-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  209. Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury
    Authors: HJ Kim, Y Joe, SY Rah, SK Kim, SU Park, J Park, J Kim, J Ryu, GJ Cho, YJ Surh, SW Ryter, UH Kim, HT Chung
    Cell Death Dis, 2018;9(11):1060.
    Species: Mouse
    Sample Types: Serum
  210. The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
    Authors: N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek
    Sci Rep, 2018;8(1):13077.
    Species: Mouse
    Sample Types:
  211. Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
    Authors: S Yi, R Chang, J Hu, Y Qiu, Q Wang, Q Cao, G Yuan, G Su, C Zhou, Y Wang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2018;59(11):4662-4669.
    Species: Human
    Sample Types: Cell Culture Supernates
  212. Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice
    Authors: RF Righetti, TM Dos Santos, LDN Camargo, LRCRB Aristótele, S Fukuzaki, FCR de Souza, FPR Santana, MVR de Agrela, MM Cruz, MIC Alonso-Val, IS Genaro, BM Saraiva-Ro, EA Leick, MA Martins, CM Prado, IFLC Tibério
    Front Pharmacol, 2018;9(0):1021.
    Species: Mouse
    Sample Types: Tissue Homogenates
  213. Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
    Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
    PLoS Pathog., 2018;14(12):e1007469.
    Species: Mouse
    Sample Types: Tissue Homogenates
  214. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
    Authors: V Neudecker, M Haneklaus, O Jensen, L Khailova, JC Masterson, H Tye, K Biette, P Jedlicka, KS Brodsky, ME Gerich, M Mack, AAB Robertson, MA Cooper, GT Furuta, CA Dinarello, LA O'Neill, HK Eltzschig, SL Masters, EN McNamee
    J. Exp. Med., 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  215. Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
    Authors: SY Lin, SY Hsieh, YT Fan, WC Wei, PW Hsiao, DH Tsai, TS Wu, NS Yang
    Autophagy, 2017;0(0):0.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  216. The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
    Authors: H Talwar, C Bauerfeld, Y Liu, L Samavati
    Data Brief, 2017;14(0):56-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  217. Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury
    Authors: GJ Martínez-C, QM Taylor, CA Wilke, AB Podsiad, BB Moore
    Mucosal Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: BALF
  218. Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
    Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  219. MyD88-dependent pro-interleukin-1? induction in dendritic cells exposed to food-grade synthetic amorphous silica
    Authors: HC Winkler, J Kornprobst, P Wick, LM von Moos, I Trantakis, EM Schraner, B Bathke, H Hochrein, M Suter, H Naegeli
    Part Fibre Toxicol, 2017;14(1):21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  220. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
    Authors: S Paetau, T Rolova, L Ning, CG Gahmberg
    Front Mol Neurosci, 2017;10(0):431.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  221. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
    Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
    Front Immunol, 2017;8(0):1777.
    Species: Mouse
    Sample Types: BALF
  222. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
    Authors: SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G N£¤ez, SL Masters, JM Murphy, K Schroder, DL Vaux, KE Lawlor, LM Lindqvist, JE Vince
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  223. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B
    Authors: J Braverman, SA Stanley
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  224. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
    Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
    PLoS ONE, 2017;12(6):e0179174.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  225. Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice
    Authors: LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi
    Sci Rep, 2017;7(1):3937.
    Species: Mouse
    Sample Types: Tissue Homogenates
  226. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection
    Authors: EE Hornick, B Banoth, AM Miller, ZR Zacharias, N Jain, ME Wilson, KN Gibson-Cor, KL Legge, GA Bishop, FS Sutterwala, SL Cassel
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  227. Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
    Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
    JCI Insight, 2017;2(17):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  228. CLEC5A is a critical receptor in innate immunity against Listeria infection
    Authors: ST Chen, FJ Li, TY Hsu, SM Liang, YC Yeh, WY Liao, TY Chou, NJ Chen, M Hsiao, WB Yang, SL Hsieh
    Nat Commun, 2017;8(1):299.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  229. Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
    Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  230. P2X7 receptor-dependent tuning of gut epithelial responses to infection
    Authors: SW Huang, C Walker, J Pennock, K Else, W Muller, MJ Daniels, C Pellegrini, D Brough, G Lopez-Cast, SM Cruickshan
    Immunol. Cell Biol, 2017;95(2):178-188.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  231. IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
    Authors: BX Ross, N Gao, X Cui, TJ Standiford, J Xu, FX Yu
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  232. Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
    Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
    Oxid Med Cell Longev, 2017;2017(0):9639035.
    Species: Mouse
    Sample Types: Tissue Homogenates
  233. Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection
    Authors: M Ivin, A Dumigan, FN de Vasconc, F Ebner, M Borroni, A Kavirayani, KN Przybyszew, RJ Ingram, S Lienenklau, U Kalinke, D Stoiber, JA Bengoechea, P Kovarik
    PLoS Pathog., 2017;13(11):e1006696.
    Species: Mouse
    Sample Types: Tissue Homogenates
  234. CRISPR/Cas9 mediated mutation of mouse IL-1? nuclear localisation sequence abolishes expression
    Authors: MJD Daniels, AD Adamson, N Humphreys, D Brough
    Sci Rep, 2017;7(1):17077.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  235. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.
    Authors: Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg
    PloS Pathogens, 2016;0(0):1553-7374.
    Species: Mouse
    Sample Types: Urine
  236. Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3
    Authors: Istvan Szatmari
    J. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  237. Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages
    J Immunol, 2016;196(11):4650-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  238. A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
    Authors: G Yang, HE Lee, JY Lee
    Sci Rep, 2016;6(0):24399.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  239. Manipulation of Interleukin-1? and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence
    Authors: D Ratner, MP Orning, KK Starheim, R Marty-Roix, MK Proulx, JD Goguen, E Lien
    J. Biol. Chem., 2016;291(19):9894-905.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  240. Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations
    Authors: Rujin Huang
    Sci. Total Environ., 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  241. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
    Sci Rep, 2016;6(0):26490.
    Species: Mouse
    Sample Types: Tissue Homogenates
  242. Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation
    J Clin Invest, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  243. C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
    J Immunol, 2016;196(5):2319-26.
    Species: Mouse
    Sample Types: BALF
  244. HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  245. Cell death is not essential for caspase-1-mediated interleukin-1? activation and secretion
    Cell Death Differ, 2016;0(0):.
  246. Dental Calculus Stimulates Interleukin-1? Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
    Authors: JL Montenegro, A Yoshimura, Z Sm, T Kaneko, Y Ozaki, T Ukai, T Miyazaki, E Latz, Y Hara
    PLoS ONE, 2016;11(9):e0162865.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  247. Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
    Authors: Marieke Pingen
    Immunity, 2016;44(6):1455-69.
    Species: Mouse
    Sample Types: Tissue Homogenates
  248. Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation
    Authors: Jand Venes R Medeiros
    Chem. Biol. Interact., 2016;260(0):129-140.
    Species: Mouse
    Sample Types: Tissue Homogenates
  249. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
    Sci Rep, 2016;6(0):29712.
    Species: Human
    Sample Types: Cell Culture Supernates
  250. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis
    PLoS ONE, 2016;11(5):e0156303.
    Species: Mouse
    Sample Types: Cell Lysates
  251. The circadian clock regulates inflammatory arthritis
    FASEB J, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  252. Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia
    MBio, 2016;7(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  253. Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
    EBioMedicine, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  254. Caspase-2 deficiency accelerates chemically induced liver cancer in mice
    Cell Death Differ, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  255. Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3
    J. Biomed. Sci, 2016;23(1):85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  256. NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
    Eur. J. Immunol., 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  257. The Carbohydrate Lectin Receptor, Dectin-1, Mediates Immune Response to Exserohilum rostratum
    Infect. Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  258. Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
    Authors: Arne Yndestad
    Biochim. Biophys. Acta, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  259. Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4
    Authors: Kamlesh K Gupta
    Biochem Biophys Res Commun, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  260. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
    Authors: Silvana Peterini Boeira
    Chem. Biol. Interact., 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  261. LRP1 modulates the microglial immune response via regulation of JNK and NF-?B signaling pathways
    J Neuroinflammation, 2016;13(1):304.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  262. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
    Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
    PLoS ONE, 2016;11(4):e0153829.
    Species: Mouse
    Sample Types: Tissue Homogenates
  263. A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease
    Authors: John S Tregoning
    mSystems, 2016;1(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  264. Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  265. Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2.
    Authors: Secor McVoy J, Oughli H, Oh U
    J Neuroinflammation, 2015;12(0):27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  266. An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1.
    Authors: Shipkowski K, Taylor A, Thompson E, Glista-Baker E, Sayers B, Messenger Z, Bauer R, Jaspers I, Bonner J
    PLoS ONE, 2015;10(6):e0128888.
    Species: Mouse
    Sample Types: BALF
  267. Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
    Authors: Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
    PLoS Pathog, 2015;11(11):e1005226.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  268. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
    Authors: Jabir M, Hopkins L, Ritchie N, Ullah I, Bayes H, Li D, Tourlomousis P, Lupton A, Puleston D, Simon A, Bryant C, Evans T
    Autophagy, 2015;11(1):166-82.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  269. Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production.
    Authors: Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H
    J Immunol, 2015;194(9):4498-506.
    Species: Mouse
    Sample Types: Serum
  270. Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.
    Authors: Sester D, Sagulenko V, Thygesen S, Cridland J, Loi Y, Cridland S, Masters S, Genske U, Hornung V, Andoniou C, Sweet M, Degli-Esposti M, Schroder K, Stacey K
    J Immunol, 2015;195(3):1233-41.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  271. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
    Authors: Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M
    J Immunol, 2015;195(5):2365-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  272. Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
    Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
    PLoS ONE, 2015;10(9):e0137273.
    Species: Mouse
    Sample Types: Tissue Homogenates
  273. Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
    Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
    J Immunol, 2015;195(6):2612-23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  274. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
    Authors: Coll R, Robertson A, Chae J, Higgins S, Munoz-Planillo R, Inserra M, Vetter I, Dungan L, Monks B, Stutz A, Croker D, Butler M, Haneklaus M, Sutton C, Nunez G, Latz E, Kastner D, Mills K, Masters S, Schroder K, Cooper M, O'Neill L
    Nat Med, 2015;21(3):248-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  275. A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
    Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
    Mucosal Immunol, 2015;8(5):982-92.
    Species: Mouse
    Sample Types: Tissue Homogenates
  276. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
    Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
    J Leukoc Biol, 2015;98(3):395-407.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  277. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
    Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
    Cell Death Differ, 2015;22(8):1313-27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  278. Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
    Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
    Infect Immun, 2014;82(8):3127-40.
    Species: Mouse
    Sample Types: Tissue Homogenates
  279. Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
    Authors: Dowling J, Becker C, Bourke N, Corr S, Connolly D, Quinn S, Pandolfi P, Mansell A, O'Neill L
    J Biol Chem, 2014;289(10):6429-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  280. Lysosomes integrate metabolic-inflammatory cross-talk in primary macrophage inflammasome activation.
    Authors: Weber K, Schilling J
    J Biol Chem, 2014;289(13):9158-71.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  281. Dendritic cell IL-1alpha and IL-1beta are polyubiquitinated and degraded by the proteasome.
    Authors: Ainscough J, Frank Gerberick G, Zahedi-Nejad M, Lopez-Castejon G, Brough D, Kimber I, Dearman R
    J Biol Chem, 2014;289(51):35582-92.
    Species: Mouse
    Sample Types: Cell Lysates
  282. PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
    Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
    J Immunol, 2014;192(5):2357-65.
    Species: Mouse
    Sample Types: Serum
  283. Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer.
    Authors: Viennois E, Xiao B, Ayyadurai S, Wang L, Wang P, Zhang Q, Chen Y, Merlin D
    Lab Invest, 2014;94(9):950-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  284. Peripheral inflammation is associated with remote global gene expression changes in the brain.
    Authors: Thomson, Carolyn, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J
    J Neuroinflammation, 2014;11(0):73.
    Species: Mouse
    Sample Types: Plasma
  285. MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection.
    Authors: Berod L, Stuve P, Swallow M, Arnold-Schrauf C, Kruse F, Gentilini M, Freitag J, Holzmann B, Sparwasser T
    Eur J Immunol, 2014;44(5):1399-409.
    Species: Mouse
    Sample Types: Serum
  286. A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
    Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
    Diabetes, 2014;63(3):850-66.
    Species: Mouse
    Sample Types: Plasma
  287. The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution.
    Authors: Hamilton, Raymond, Buckingham, Sarah, Holian, Andrij
    Int J Mol Sci, 2014;15(4):6815-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  288. Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.
    Authors: Noelker C, Morel L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W, Henze C, Michel P, Dodel R, Lu L, Hirsch E, Hunot S, Hartmann A
    J Neuroinflammation, 2014;11(0):86.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  289. Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
    Authors: Benmohamed F, Medina M, Wu Y, Maschalidi S, Jouvion G, Guillemot L, Chignard M, Manoury B, Touqui L
    PLoS ONE, 2014;9(3):e90466.
    Species: Mouse
    Sample Types: BALF
  290. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
    Authors: Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, Elian S, Martins F, Pereira D, Reed G, Fitzgerald K, Golenbock D, Gazzinelli R
    PLoS Pathog, 2014;10(1):e1003885.
    Species: Mouse
    Sample Types: Whole Blood
  291. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
    PLoS ONE, 2014;9(12):e114884.
    Species: Mouse
    Sample Types: Tissue Homogenates
  292. Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
    Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
    PLoS ONE, 2014;9(1):e87927.
    Species: Mouse
    Sample Types: Plasma
  293. Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
    Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
    Obesity (Silver Spring), 2014;22(3):663-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  294. No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
    Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
    PLoS ONE, 2014;9(9):e106420.
    Species: Mouse
    Sample Types: Serum
  295. Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor.
    Authors: Goncalves-de-Albuquerque C, Burth P, Silva A, de Moraes I, Oliveira F, Santelli R, Freire A, de Lima G, da Silva E, da Silva C, Morandi V, Bozza P, Younes-Ibrahim M, de Castro Faria Neto H, de Castro Faria M
    Respir Res, 2014;15(0):93.
    Species: Mouse
    Sample Types: BALF
  296. ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.
    Authors: Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
    Am J Pathol, 2014;184(5):1287-98.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  297. IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
    Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
    Proc Natl Acad Sci U S A, 2014;111(1):367-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  298. Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation.
    Authors: Cengiz P, Kintner D, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D
    PLoS ONE, 2014;9(1):e84294.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  299. Staphylococcus aureus infection of mice expands a population of memory gammadelta T cells that are protective against subsequent infection.
    Authors: Murphy A, O'Keeffe K, Lalor S, Maher B, Mills K, McLoughlin R
    J Immunol, 2014;192(8):3697-708.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  300. Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO.
    Authors: Biswas R, Hamilton R, Holian A
    J Immunol Res, 2014;2014(0):304180.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  301. The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
    Authors: Hernandes M, D'Avila J, Trevelin S, Reis P, Kinjo E, Lopes L, Castro-Faria-Neto H, Cunha F, Britto L, Bozza F
    J Neuroinflammation, 2014;11(0):36.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  302. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  303. Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.
    Authors: Calil I, Zarpelon A, Guerrero A, Alves-Filho J, Ferreira S, Cunha F, Cunha T, Verri W
    PLoS ONE, 2014;9(3):e90013.
    Species: Mouse
    Sample Types: Tissue Homogenates
  304. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
    Authors: Redlich S, Ribes S, Schutze S, Nau R
    J Neuroinflammation, 2014;11(0):108.
    Species: Mouse
    Sample Types: Tissue Homogenates
  305. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
    Authors: Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, Kim T, Yoon S, Min J, Na H, Lee S, Lee H, Lee Y, Lee H, Choi I
    PLoS Pathog, 2013;9(10):e1003646.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  306. Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice.
    Authors: Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P
    PLoS ONE, 2013;8(2):e56636.
    Species: Mouse
    Sample Types: BALF
  307. The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
    Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
    PLoS ONE, 2013;8(11):e80471.
    Species: Mouse
    Sample Types: Tissue Homogenates
  308. A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
    Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
    PLoS ONE, 2013;8(12):e84107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  309. Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.
    Authors: Alvarez-Fischer D, Noelker C, Vulinovic F, Grunewald A, Chevarin C, Klein C, Oertel W, Hirsch E, Michel P, Hartmann A
    PLoS ONE, 2013;8(4):e61700.
    Species: Mouse
    Sample Types: Tissue Homogenates
  310. Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation.
    Authors: Horton J, Hudak K, Chung E, White A, Scroggins B, Burkeen J, Citrin D
    Stem Cells, 2013;31(10):2231-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  311. A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
    Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
    EMBO Mol Med, 2013;5(4):516-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  312. Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones.
    Authors: Beynon A, Brown M, Wright R, Rees M, Sheldon I, Davies J
    J Neuroinflammation, 2013;10(0):40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  313. Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
    Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
    PLoS ONE, 2013;8(11):e80723.
    Species: Mouse
    Sample Types: BALF
  314. NLRP3 inflammasome activation by Paracoccidioides brasiliensis.
    Authors: Tavares A, Magalhaes K, Almeida R, Correa R, Burgel P, Bocca A
    PLoS Negl Trop Dis, 2013;7(12):e2595.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  315. Further evidence for an anti-inflammatory role of artesunate in experimental cerebral malaria.
    Authors: Miranda A, Brant F, Rocha N, Cisalpino D, Rodrigues D, Souza D, Machado F, Rachid M, Teixeira A, Campos A
    Malar J, 2013;12(0):388.
    Species: Mouse
    Sample Types: Tissue Homogenates
  316. Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
    Authors: Ermler M, Traylor Z, Patel K, Schattgen S, Vanaja S, Fitzgerald K, Hise A
    Virology, 2013;449(0):174-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  317. Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.
    Authors: Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S
    J Immunol, 2013;190(9):4773-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  318. TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
    Authors: Gowda NM, Wu X, Gowda DC
    J. Immunol., 2012;188(10):5073-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  319. Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
    Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
    Eur. J. Immunol., 2012;42(5):1226-36.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  320. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury.
    Authors: Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, Iwakura Y, Atsumi T, Shioda S
    J Neuroinflammation, 2012;9(0):65.
    Species: Mouse
    Sample Types: Tissue Homogenates
  321. Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
    Authors: Serezani CH, Kane S, Collins L
    J. Immunol., 2012;189(2):906-15.
    Species: Mouse
    Sample Types: BALF
  322. Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
    Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
    Infect. Immun., 2012;80(1):100-9.
    Species: Mouse
    Sample Types: Serum
  323. Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response.
    Authors: Oh J, Lee R, Yu J, Ko J, Lee H, Ko A, Roddy G, Prockop D
    Mol Ther, 2012;20(11):2143-52.
    Species: Mouse
    Sample Types: Tissue Homogenates
  324. Dok2 mediates the CD200Fc attenuation of Abeta-induced changes in glia.
    Authors: Lyons A, Downer E, Costello D, Murphy N, Lynch M
    J Neuroinflammation, 2012;9(0):107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  325. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
    Authors: Barber DL, Mayer-Barber KD, Feng CG
    J. Immunol., 2011;186(3):1598-607.
    Species: Mouse
    Sample Types: BALF
  326. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  327. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011;186(9):5425-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  328. P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases.
    Authors: Lopez-Castejon G, Theaker J, Pelegrin P
    J. Immunol., 2010;185(4):2611-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  329. Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
    Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
    J. Immunol., 2010;185(0):2516-24.
    Species: Mouse
    Sample Types: Serum
  330. Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
    Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
    Eur. J. Immunol., 2010;40(8):2221-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  331. Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
    Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
    J. Immunol., 2010;184(4):2076-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  332. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
    Authors: Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT
    Science, 2010;328(5975):228-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  333. IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
    Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
    Brain Behav. Immun., 2010;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  334. Tyrosine kinase 2 controls IL-1beta production at the translational level.
    Authors: Radwan M, Stiefvater R, Grunert T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B
    J. Immunol., 2010;185(6):3544-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  335. A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
    Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
    J. Immunol., 2010;185(11):6741-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  336. Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
    Authors: Sheldon IM, Roberts MH,
    PLoS ONE, 2010;5(9):e12906.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  337. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
    Authors: Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, Maroteaux L
    Circ. Res., 2009;104(1):113-23.
    Species: Mouse
    Sample Types: Plasma
  338. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009;183(4):2642-9.
    Species: Mouse
    Sample Types: BALF
  339. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.
    Authors: Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H
    Eur. J. Immunol., 2009;39(3):820-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  340. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
    Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
    J. Immunol., 2009;183(12):8195-202.
    Species: Mouse
    Sample Types: BALF
  341. A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.
    Authors: Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM
    J. Nutr., 2009;139(12):2351-7.
    Species: Mouse
    Sample Types: Serum
  342. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
    Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
    J. Immunol., 2009;183(3):2027-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
  343. Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
    Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
    Circulation, 2008;118(20):2063-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  344. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
    Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
    J. Immunol., 2008;180(6):4022-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  345. Mutual modulation between interleukin-10 and interleukin-6 induced by Rhodococcus aurantiacus infection in mice.
    Authors: Yimin, Kohanawa M, Ozaki M, Haga S, Fujikawa K, Zhao S, Kuge Y, Tamaki N
    Microbes Infect., 2008;10(14):1450-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  346. Induction of IL-33 expression and activity in central nervous system glia.
    Authors: Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT
    J. Leukoc. Biol., 2008;84(3):631-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  347. Divergent effects of hypoxia on dendritic cell functions.
    Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
    Blood, 2008;112(9):3723-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  348. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
    Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
    J. Immunol., 2008;180(2):1169-78.
    Species: Mouse
    Sample Types: Tissue Homogenates
  349. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007;111(8):4096-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  350. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
    Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
    J. Clin. Invest., 2007;117(12):3786-99.
    Species: Mouse
    Sample Types: BALF
  351. Deletion of TLR5 results in spontaneous colitis in mice.
    Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
    J. Clin. Invest., 2007;117(12):3909-21.
    Species: Mouse
    Sample Types: Serum
  352. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
    Authors: Schell JB, Crane CA, Smith MF, Roberts MR
    J. Neuroimmunol., 2007;189(1):75-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  353. ABCC transporter inhibition reduces zymosan-induced peritonitis.
    Authors: Leite DF, Echevarria-Lima J, Ferreira SC, Calixto JB, Rumjanek VM
    J. Leukoc. Biol., 2007;82(3):630-7.
    Species: Mouse
    Sample Types: Tissue Secretion
  354. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007;26(4):445-59.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  355. Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
    Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
    Vaccine, 2007;25(37):6730-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  356. CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
    Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
    Neurobiol. Dis., 2007;29(2):336-53.
    Species: Mouse
    Sample Types: Plasma
  357. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
    Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
    J. Leukoc. Biol., 2007;82(3):678-85.
    Species: Mouse
    Sample Types: Plasma
  358. Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
    Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
    J. Immunol., 2007;179(10):7079-86.
    Species: Mouse
    Sample Types: Tissue Homogenates
  359. Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
    Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
    Crit. Care Med., 2007;35(2):510-8.
    Species: Mouse
    Sample Types: Plasma
  360. Anti-tumor necrosis factor alpha F(ab')2 antibody fragments protect in murine polymicrobial sepsis: concentration and early intervention are fundamental to the outcome.
    Authors: Marquez-Velasco R, Bojalil R, Buelna A, Flores-Guzman F, Estevez-Ramirez J, Laguna J, Hernandez AM, Diaz-Quinonez A, Paniagua-Solis JF
    Inflamm. Res., 2006;55(9):378-84.
    Species: Mouse
    Sample Types: Serum
  361. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
    Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
    J. Immunol., 2006;177(11):7980-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  362. Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
    Authors: Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(4):L710-7.
    Species: Mouse
    Sample Types: BALF
  363. The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
    Authors: Powell JM, Sonnenfeld G
    J. Interferon Cytokine Res., 2006;26(1):34-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  364. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.
    Authors: Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R
    J. Immunol., 2006;177(9):6370-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  365. An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
    Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
    Am. J. Respir. Cell Mol. Biol., 2005;33(5):470-5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  366. Attenuation of primary nonfunction for syngeneic islet graft using sodium 4-phenylbutyrate.
    Authors: Fu SH, Chen ST, Hsu BR
    Transplant. Proc., 2005;37(4):1830-1.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  367. Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
    Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
    Biol. Pharm. Bull., 2005;28(6):1010-5.
    Species: Mouse
    Sample Types: Pleural Fluid
  368. Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
    Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
    J. Appl. Physiol., 2004;97(4):1437-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  369. Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.
    Authors: Esen N, Tanga FY, DeLeo JA, Kielian T
    J. Neurochem., 2004;88(3):746-58.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  370. TLR2 deletion promotes arthritis through reduction of IL-10.
    Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
    J Leukoc Biol, 0;93(5):751-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  371. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
    Authors: Evans C, Miners J, Piva G, Willis C, Heard D, Kidd E, Good M, Kehoe P
    Acta Neuropathol, 0;139(3):485-502.
    Species: Mouse
    Sample Types: Tissue Homogenates

FAQs

  1. Does the Mouse IL-1 beta/IL-1F2 DuoSet ELISA (Catalog DY401) crosss-react with the pro-form of Mouse IL-1 beta?

    • The Mouse IL-1 beta/IL-1F2 DuoSet ELISA is designed to detect mature mouse IL-1 beta and the assay is calibrated against the mature form of mouse IL-1 beta. It is possible that the kit also detects the pro-form, however, R&D Systems has not performed this characterization.

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Reviews for Mouse IL-1 beta/IL-1F2 DuoSet ELISA

Average Rating: 4.8 (Based on 28 Reviews)

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Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/15/2022
Sample Tested: BAL fluid

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/24/2022
Sample Tested: whole blood supernatant

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 03/03/2022
Sample Tested: J774A.1 mouse reticulum cell sarcoma macrophage cell line

Optimisation of cytokine response and cell numbers


Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 03/01/2022
Sample Tested: Cell Lysates

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/28/2022
Sample Tested: BMDM supernates,Cell Culture Supernates,J774A.1 mouse reticulum cell sarcoma macrophage cell line

Except for the highest standard all other standards worked well


Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/13/2021
Sample Tested: serum and cell supernatant

we have used this kit for LPS stimulated in vivo and in vitro experiments. It works very well and efficiently.


Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/06/2021
Sample Tested: Tissue Lysates

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Martin Torres on 09/23/2021
Sample Tested: Mice serum

Mouse IL-1b ELISA kit was used to assess IL-1b levels in serum after 12-weeks treatment of adult C57BL7/6J mice with a high-fat diet treatment. Results were accurate and showed low intra-experimental variation (less than 6 %). The picture shows the standard diet (SD), high-fat diet (HFD), and two concentrations of corn pericarp extract (200 and 500 parts per million of extract).


Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/11/2020
Sample Tested: Human cell conditioned medium

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Mustafa Girnary on 10/20/2020
Sample Tested: THP-1 human acute monocytic leukemia cell line

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 11/10/2019
Sample Tested: Cell culture supernatant,RAW 264.7 mouse monocyte/macrophage cell line

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/11/2019
Sample Tested: mouse macrophages

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Wen Li on 08/06/2019
Sample Tested: Bone marrow-derived dendritic cells

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/20/2019
Sample Tested: Adult lung

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ivan Luzardo on 12/11/2018
Sample Tested: Serum and Plasma

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Alejandra Palomino Antolín on 07/27/2018
Sample Tested: Brain (glial cell in hippocampus)

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/17/2018
Sample Tested: J774A.1 mouse reticulum cell sarcoma macrophage cell line

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/13/2018
Sample Tested: Cell culture supernatant

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ella Zeldich on 11/22/2017
Sample Tested: mouse primary microglia cells

We needed to calibrate the dilutions of our samples.


Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/27/2017
Sample Tested: Peritoneal resident macrophages

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/21/2017
Sample Tested: Brain tissue

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/24/2017
Sample Tested: Plasma

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/22/2017
Sample Tested: Whole blood

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/19/2017
Sample Tested: Lung tissue

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/05/2016
Sample Tested: Mouse plasma samples

Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ariela Haimovich on 05/24/2016
Sample Tested: BMDC cells stimulated with LPS for 4 hrs,Bone marrow-derived dendritic cells

Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Jacqueline Kimmey on 04/05/2016
Sample Tested: murine lung homogenate supernatant

lungs were homogenized in PBS-T, and sup was filtered through 0.22um filter before use. Homogenate was diluted 1:3 for analysis by ELISA.


Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Anonymous on 10/26/2015
Sample Tested: Purified mouse IL-1beta protein

50ul of murine IL-1beta Capture antibody (4ug/mL) was coated per well of a 96 well plate at 4 degrees overnight. Purified IL-1beta standard was diluted (7 fold) and assayed to ensure the quality of the ELISA. Mouse IL-1beta Detector antibody was added (2h @ RT) followed by a 20 min incubation with Streptavidin-HRP. Substrate solution was added to measure IL-1beta concentration according to the manufactures protocol. The standard curve looked great as can be seen by calculation of the R- squared value. Highly recommend doing ELISA's using kits from R&D.
Buffer: 7-point standard curve