Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Biotin

Antibody Source

Polyclonal Goat IgG
View all Noggin Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Noggin
Leu20-Cys232
Accession # P97466

Specificity

Detects mouse Noggin in Western blots.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Mouse Noggin Biotinylated Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Mouse Noggin (Catalog # 1967-NG)

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: Noggin

Noggin is a 232 amino acid (aa), ~31 kDa homodimer-forming glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Noggin is expressed in defined areas during development and in the adult central nervous system and peripheral tissues such as lung, skeletal muscle, and skin. It is important for neural tube, somite and cardiomyocyte growth and patterning, and for limiting chondrocyte growth. Noggin is secreted but probably remains close to the cell surface due to its binding of heparin-containing proteoglycans. Mature human, mouse, and rat Noggin share 99% aa sequence identity.

Alternate Names

NOG, SYM1, SYNS1, SYNS1A

Entrez Gene IDs

9241 (Human); 18121 (Mouse)

Gene Symbol

NOG

UniProt

P97466

Additional Noggin Products

Product Documents for Mouse Noggin Biotinylated Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Mouse Noggin Biotinylated Antibody

For research use only

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FAQs

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