Mouse SECTM1A Antibody

Catalog # Availability Size / Price Qty
SECTM1A in Mouse Embryo.
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Product Details
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Mouse SECTM1A Antibody Summary

Species Reactivity
Detects mouse SECTM1A in direct ELISAs.
Polyclonal Sheep IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant mouse SECTM1A
Accession # Q921W8
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.


Recommended Concentration
5-15 µg/mL
See below
Blockade of Receptor-ligand Interaction
In a functional ELISA, 0.2-1 µg/mL of this antibody willblock 50% of the binding of 0.1 µg/mL of Recombinant Mouse SECTM1A Fc Chimera (Catalog # 7837-ST) to immobilized Recombinant Mouse CD7 (Catalog # 8145-CD) coated at 1 µg/mL (100 µL/well).

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Immunohistochemistry SECTM1A antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr). View Larger

SECTM1A in Mouse Embryo. SECTM1A was detected in immersion fixed frozen sections of mouse embryo (13 d.p.c.) using Sheep Anti-Mouse SECTM1A Antigen Affinity-purified Polyclonal Antibody (Catalog # AF7837) at 15 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS019) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Frozen Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SECTM1A

SECTM1A (Secreted and Transmembrane 1A), is 192 amino acid (aa) protein that shares approximately 45‑51%, 81%, and 43% aa sequence identity with human SECTM1 (also called K12), rat SECTM1, and mouse SECTM1B/K12, respectively, and appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi‑like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts (1‑3). Stimulation with IFN‑ gamma is often necessary to detect human SECTM1 expression, and it is thought to be an interferon early‑response gene (1‑5). Mouse SECTM1A cDNA encodes a signal sequence, an extracellular domain with four potential N‑linked glycosylation sites, a transmembrane sequence, and a very short (approximately 6 aa) cytoplasmic sequence (6). SECTM1 proteins from human and mouse show species‑specific binding of CD7 and co‑stimulation of T cells, including enhancement of CD3‑induced proliferation (2‑4).

  1. Slentz-Kesler, K.A. et al. (1998) Genomics 47:327.
  2. Lam, G.K. et al. (2005) J. Clin. Immunol. 25:41.
  3. Wang, T. et al. (2012) J. Leukoc. Biol. 91:449.
  4. Lyman, S.D. et al. (2000) J. Biol. Chem. 275:3431.
  5. Huyton, T. et al. (2011) Biochim. Biophys. Acta 1810:1294.
  6. Swiss-Prot Accession # Q921W8.
Long Name
Secreted and Transmembrane 1A
Entrez Gene IDs
209588 (Mouse); 287885 (Rat)
Alternate Names

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