Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot, ELISA, Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free
View all MTCH2 Primary Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2. Amino Acid Squence: LQHYQESDKGEELGPG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for MTCH2 Antibody - BSA Free

Western Blot: MTCH2 AntibodyBSA Free [NBP1-76998]

Western Blot: MTCH2 AntibodyBSA Free [NBP1-76998]

Western Blot: MTCH2 Antibody [NBP1-76998] - 293 cell lysate with MTCH2 antibody at 1 ug/mL.
MTCH2 Antibody - BSA Free

Immunohistochemistry: MTCH2 Antibody - BSA Free [NBP1-76998] -

Immunohistochemistry: MTCH2 Antibody - BSA Free [NBP1-76998] - Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 u/mL.
MTCH2 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: MTCH2 Antibody - BSA Free [NBP1-76998] -

Immunocytochemistry/ Immunofluorescence: MTCH2 Antibody - BSA Free [NBP1-76998] - Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 ug/mL.

Applications for MTCH2 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: MTCH2

Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.

Alternate Names

2310034D24Rik, Met-induced mitochondrial protein, MIMP, mitochondrial carrier 2, mitochondrial carrier homolog 2, mitochondrial carrier homolog 2 (C. elegans)

Gene Symbol

MTCH2

UniProt

NP_055157 (Human)

Additional MTCH2 Products

Product Documents for MTCH2 Antibody - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for MTCH2 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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