Normal Goat IgG Control

Name: Normal Goat IgG Control
Brand: R&D Systems
Rating: 4.4 (11 reviews)

(210 citations)

(11 Reviews)

Datasheet / CoA / SDS

Control

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Product Details

Citations (210)

FAQs

Supplemental Products

Reviews

Specificity

Serum was obtained from naive (non-immunized) goats and purified for use as normal goat IgG.
Source

Polyclonal Goat IgG
Purification

Protein A or G purified
Immunogen

NA
Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.
Label

Unconjugated

Product Datasheets

Product Datasheet

COA

Certificate of Analysis Lookup

Certificate of Analysis Request Form

SDS

Applications

Recommended
Concentration

Sample

Control

Negative control for use in conjunction with R&D Systems antibodies. Use at the same concentration as the detection antibody.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

Control

click image to view larger

Detection of NormalGoat IgG Control by Flow Cytometry SH-SY5Y human neuroblastoma cell line was stained with Goat Anti-Human/Mouse/RatEphrin-B2 Antigen Affinity-purified Polyclonal Antibody (Catalog #AF496,filled histogram) or Normal Goat IgG Isotype Control Antibody(Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugatedAnti-Goat IgG Secondary Antibody
(Catalog #F0107).

Preparation and Storage

Reconstitution

Dissolve the lyophilized goat IgG in sterile PBS, pH 7.4. If 1 mL of PBS is used, the antibody concentration will be 1 mg/mL.
Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IgG

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Long Name:

Immunoglobulin G

Alternate Names:

IgG; immunoglobulin heavy constant gamma 1 (G1m marker)

Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

210 Citations: Showing 1 - 10
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Species	Applications	Sample Type
The SMAD2/3 interactome reveals that TGF? controls m6A mRNA methylation in pluripotency Authors: A Bertero, S Brown, P Madrigal, A Osnato, D Ortmann, L Yiangou, J Kadiwala, NC Hubner, IR de Los Moz, C Sadée, AS Lenaerts, S Nakanoh, R Grandy, E Farnell, J Ule, HG Stunnenber, S Mendjan, L Vallier Nature, 2018;555(7695):256-259. Species: Human Sample Type: Protein Application: IP Tumor-derived exosomes induce PD1+ macrophage population in human gastric cancer that promotes disease progression Authors: F Wang, B Li, Y Wei, Y Zhao, L Wang, P Zhang, J Yang, W He, H Chen, Z Jiao, Y Li Oncogenesis, 2018;7(5):41. Species: Human Sample Type: Whole Cells Application: Functional Assay Gdnf, Neurturin and Artemin Activate and Sensitize Bone Afferent Neurons and Contribute To Inflammatory Bone Pain Authors: S Nencini, M Ringuet, DH Kim, C Greenhill, JJ Ivanusic J. Neurosci., 2018;0(0):. Species: Rat Sample Type: In Vivo Application: Isotype control ATP-binding cassette member B5 (ABCB5) promotes tumor cell invasiveness in human colorectal cancer Authors: Q Guo, T Grimmig, G Gonzalez, A Giobbie-Hu, G Berg, N Carr, BJ Wilson, P Banerjee, J Ma, JS Gold, B Nandi, Q Huang, AM Waaga-Gass, CG Lian, GF Murphy, MH Frank, M Gasser, NY Frank J. Biol. Chem., 2018;0(0):. Species: Xenograft Sample Type: Whole Cells Application: Flow Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease Authors: X Qu, X Dang, W Wang, Y Li, D Xu, D Shang, Y Chang Mediators Inflamm., 2018;2018(0):7501851. Application: Isotype control Osteopontin contributes to effective neutrophils recruitment, IL-1? production, and apoptosis in Aspergillus fumigatus keratitis Authors: G Zhao, M Hu, C Li, J Lee, K Yuan, G Zhu, C Che Immunol. Cell Biol., 2018;0(0):. Species: Human Sample Type: Whole Cells Application: Neut Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea Authors: P Mirabelli, A Mukwaya, A Lennikov, M Xeroudaki, B Peebo, M Schaupper, N Lagali Sci Rep, 2017;7(1):7616. Species: Rat Sample Type: In Vivo Application: Neut IL-17A Produced by Innate Lymphoid Cells Is Essential for Intestinal Ischemia-Reperfusion Injury Authors: M Geha, MG Tsokos, RE Bosse, T Sannikova, Y Iwakura, JJ Dalle Lucc, R De Waal Ma, GC Tsokos J. Immunol., 2017;0(0):. Species: Mouse Sample Type: In Vivo Application: Neut Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He Autophagy, 2017;0(0):0. Species: Human Sample Type: Whole Cells Application: Neut Pan-cancer EMT-signature identifies RBM47 down-regulation during colorectal cancer progression Authors: M Rokavec, M Kaller, D Horst, H Hermeking Sci Rep, 2017;7(1):4687. Species: Human Sample Type: Cell Lysates Application: ChIP Surface Toll-Like Receptor 3 Expression in Metastatic Intestinal Epithelial Cells induces Inflammatory Cytokine Production and Promotes Invasiveness Authors: M Bugge, B Bergstrom, OK Eide, H Solli, IF Kjønstad, J Stenvik, T Espevik, NJ Nilsen J. Biol. Chem., 2017;0(0):. Species: Human Sample Type: Whole Cells Application: Neut MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo Nat Commun, 2017;8(0):16003. Species: Mouse Sample Type: Whole Tissue Application: IHC A split-luciferase complementation, real-time reporting assay enables monitoring of the disease-associated transmembrane protein TREM2 in live cells Authors: MM Varnum, KA Clayton, A Yoshii-Kit, G Yonemoto, L Koro, S Ikezu, T Ikezu J. Biol. Chem., 2017;0(0):. Species: Mouse Sample Type: Whole Cells Application: Functional Assay Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1? Authors: KM Tsang, JS Hyun, KT Cheng, M Vargas, D Mehta, M Ushio-Fuka, L Zou, KV Pajcini, J Rehman, AB Malik Stem Cell Reports, 2017;0(0):. Species: Mouse Sample Type: Whole Cells Application: Flow Integrin ?3/Akt signaling contributes to platelet-induced hemangioendothelioma growth Authors: R Gu, X Sun, Y Chi, Q Zhou, H Xiang, DB Bosco, X Lai, C Qin, KF So, Y Ren, XM Chen Sci Rep, 2017;7(1):6455. Species: Mouse Sample Type: Whole Cells Application: Flow control TPL-2 restricts Ccl24-dependent immunity to Heligmosomoides polygyrus Authors: Y Kannan, LJ Entwistle, VS Pelly, J Perez-Llor, AW Walker, SC Ley, MS Wilson PLoS Pathog., 2017;13(7):e1006536. Species: Mouse Sample Type: In Vivo Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray JCI Insight, 2017;2(17):. Species: Mouse Sample Type: In Vivo Application: In vivo Human Immunodeficiency Virus Type-1 Myeloid Derived Suppressor Cells Inhibit Cytomegalovirus Inflammation through Interleukin-27 and B7-H4 Authors: A Garg, R Trout, SA Spector Sci Rep, 2017;7(0):44485. Species: Human Sample Type: Whole Cells Application: Neut Scavenger receptor collectin placenta 1 is a novel receptor involved in the uptake of myelin by phagocytes Authors: JF Bogie, J Mailleux, E Wouters, W Jorissen, E Grajchen, J Vanmol, K Wouters, N Hellings, J Van Horsen, T Vanmierlo, JJ Hendriks Sci Rep, 2017;7(0):44794. Combined Effects of Androgen and Growth Hormone on Osteoblast Marker Expression in Mouse C2C12 and MC3T3-E1 Cells Induced by Bone Morphogenetic Protein Authors: K Kimura, T Terasaka, N Iwata, T Katsuyama, M Komatsubar, R Nagao, K Inagaki, F Otsuka J Clin Med, 2017;6(1):. Species: Mouse Sample Type: Whole Cells Application: Neut Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation Authors: S Esnault, EE Torr, K Bernau, MW Johansson, EA Kelly, N Sandbo, NN Jarjour PLoS ONE, 2017;12(1):e0170207. Species: Human Sample Type: Whole Cells Application: ICC Ctrl Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A Authors: R Velázquez-, M Law, J Bukh, J Prentoe PLoS Pathog, 2017;13(2):e1006214. Species: Human Sample Type: Whole Cells Application: Ctrl Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill,, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury JCI Insight, 2017;2(17):. Species: Mouse Sample Type: Complex Sample Type Application: Isotype control Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation Authors: SN Cross, JA Potter, P Aldo, JY Kwon, M Pitruzzell, M Tong, S Guller, CV Rothlin, G Mor, VM Abrahams J. Immunol., 2017;0(0):. Species: Human Sample Type: Whole Tissue Application: Neut Interleukin 27 is increased in carotid atherosclerosis and promotes NLRP3 inflammasome activation Authors: I Gregersen, Ø Sandanger, ET Askevold, EL Sagen, K Yang, S Holm, TM Pedersen, M Skjelland, K Krohg-Søre, TV Hansen, TB Dahl, K Otterdal, T Espevik, P Aukrust, A Yndestad, B Halvorsen PLoS ONE, 2017;12(11):e0188387. Species: Human Sample Type: Whole Cells Application: Neut Ctrl IFN-?4 Attenuates Antiviral Responses by Enhancing Negative Regulation of IFN Signaling Authors: AA Obajemu, N Rao, KA Dilley, JM Vargas, F Sheikh, RP Donnelly, RS Shabman, EG Meissner, L Prokunina-, OO Onabajo J. Immunol., 2017;0(0):. Species: Human Sample Type: Whole Cells Application: Ctrl Netrin 1 mediates protective effects exerted by insulin-like growth factor 1 on cochlear hair cells Authors: K Yamahara, T Nakagawa, J Ito, K Kinoshita, K Omori, N Yamamoto Neuropharmacology, 2017;119(0):26-39. Species: Mouse Sample Type: Whole Cells Application: Functional Assay Chronic hepatitis C liver microenvironment: role of the Th17/Treg interplay related to fibrogenesis Authors: DA Rios, P Valva, PC Casciato, S Frias, M Soledad Ca, MI Gaillard, L Bezrodnik, J Bandi, O Galdame, B Ameigeiras, D Krasniansk, C Brodersen, E Mullen, EN Matteo, MV Preciado Sci Rep, 2017;7(1):13283. Species: Human Sample Type: Whole Tissue Application: IHC Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells Authors: Y Shlyakhtin, V Pavet, H Gronemeyer Cell Death Dis, 2017;8(8):e3025. Species: Human Sample Type: Cell Lysates Application: IP Triple Staining Including FOXA2 Identifies Stem Cell Lineages Undergoing Hepatic and Biliary Differentiation in Cirrhotic Human Liver Authors: Leslie E Rogler J. Histochem. Cytochem., 2016;0(0):. Species: Human Sample Type: Whole Tissue Application: ICC Noncanonical WNT-5A signaling impairs endogenous lung repair in COPD Authors: Hoeke A Baarsma J. Exp. Med, 2016;0(0):. Species: Mouse Sample Type: In Vivo Application: Ctrl Dickkopf-1 promotes hematopoietic regeneration via direct and niche-mediated mechanisms Nat. Med, 2016;0(0):. Species: Mouse Sample Type: In Vivo Application: In vivo control Macrophagic control of the response to uropathogenic E. coli infection by regulation of iron retention in an IL-6-dependent manner Authors: Nana Owusu-Boai Immun Inflamm Dis, 2016;4(4):413-426. Species: Mouse Sample Type: Whole Cells Application: Bioassay PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently Authors: L Zheng, C Zhao, Y Du, X Lin, Y Jiang, C Lee, G Tian, J Mi, X Li, Q Chen, Z Ye, L Huang, S Wang, X Ren, L Xing, W Chen, D Huang, Z Gao, S Zhang, W Lu, Z Tang, B Wang, R Ju, X Li Oncotarget, 2016;7(47):77902-77915. Species: Mouse Sample Type: Whole Cells Application: Neut Zika virus cell tropism in the developing human brain and inhibition by azithromycin Proc. Natl. Acad. Sci. U.S.A., 2016;113(50):14408-14413. Species: Human Sample Type: Whole Cells Application: Neut Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy Sci Rep, 2016;6(0):37209. Species: Mouse Sample Type: In Vivo Application: In vivo control HEREGULIN/ErbB3 SIGNALING ENHANCES CXCR4-DRIVEN Rac1 ACTIVATION AND BREAST CANCER CELL MOTILITY VIA HIF-1? Mol Cell Biol, 2016;0(0):. Species: Human Sample Type: Chromatin Application: ChIP Assay Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway. Authors: Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, Buchheit K, Bhattacharya N, Laidlaw T, Katz H, Boyce J J Immunol, 2016;195(8):3537-45. Species: Mouse Sample Type: In Vivo Application: In vivo The Chemokine CCL2 Mediates the Seizure-enhancing Effects of Systemic Inflammation Authors: C Cerri, S Genovesi, M Allegra, F Pistillo, U Püntener, A Guglielmot, VH Perry, Y Bozzi, M Caleo J Neurosci, 2016;36(13):3777-88. Species: Mouse Sample Type: In Vivo Application: In vivo A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo. Authors: Wong J, Krueger K, Costa M, Aggarwal A, Du H, McLaughlin T, Feldman B Sci Signal, 2016;9(451):ra103. Species: Mouse Sample Type: In Vivo Application: Bioassay Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33 Authors: Sara Khaleghparast Athari Arthritis Res Ther, 2016;18(1):143. Species: Mouse Sample Type: Whole Tissue Application: IHC - Paraffin embedded The Effect of Chronic Hepatitis B Virus Infection on BDCA3+ Dendritic Cell Frequency and Function PLoS ONE, 2016;11(8):e0161235. Species: Human Sample Type: Whole Cells Application: Bioassay Expression and function of IL-1R8 (TIR8/SIGIRR), a regulatory member of the IL-1 receptor family in platelets Authors: Achille Anselmo Cardiovasc Res, 2016;0(0):. Species: Human Sample Type: Whole Cells Application: Flow Ctrl Interleukin-33 from Monocytes Recruited to the Lung Contributes to House Dust Mite-Induced Airway Inflammation in a Mouse Model Authors: Hiroki Tashiro PLoS ONE, 2016;11(6):e0157571. Species: Mouse Sample Type: Whole Tissue Application: IHC - Paraffin embedded Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization Mol Ther Methods Clin Dev, 2016;3(0):16056. Species: Mouse Sample Type: In Vivo Application: In vivo Antihypoxic Potentiation of Standard Therapy for Experimental Colorectal Liver Metastasis through Myo-Inositol Trispyrophosphate Clin Cancer Res, 2016;0(0):. Species: Mouse Sample Type: In Vivo Application: In vivo The Tissue Fibrinolytic System Contributes to the Induction of Macrophage Function and CCL3 during Bone Repair in Mice. Authors: Kawao N, Tamura Y, Horiuchi Y, Okumoto K, Yano M, Okada K, Matsuo O, Kaji H PLoS ONE, 2015;10(4):e0123982. Species: Mouse Sample Type: In Vivo Application: In vivo Monocyte chemoattractant protein 1 (MCP-1/CCL2) contributes to thymus atrophy in acute myeloid leukemia. Authors: Driss V, Quesnel B, Brinster C Eur J Immunol, 2015;45(2):396-406. Species: Mouse Sample Type: In Vivo Application: In vivo The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71. Authors: Leong, Shi Yun, Ong, Bryan Ki, Chu, Justin J PLoS Pathog, 2015;11(3):e1004686. Species: Human Sample Type: Whole Cells Application: Neut Expression of surfactant protein D in airways of asthmatics and interleukin-13 modulation of surfactant protein D in human models of airway epithelium. Authors: Xu J, Singhera G, Dorscheid D Respir Res, 2015;16(0):26. Species: Human Sample Type: Whole Cells Application: Neut IGFBP-4 and -5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells. Authors: Crosley, Erin J, Dunk, Caroline, Beristain, Alexande, Christians, Julian K Reprod Biol Endocrinol, 2015;12(0):123. Species: Human Sample Type: Whole Tissue Application: IHC Ctrl Crucial role of IL1beta and C3a in the in vitro-response of multipotent mesenchymal stromal cells to inflammatory mediators of polytrauma. Authors: Hengartner N, Fiedler J, Schrezenmeier H, Huber-Lang M, Brenner R PLoS ONE, 2015;10(1):e0116772. Species: Human Sample Type: Whole Cells Application: Blocking Discovery of molecular markers to discriminate corneal endothelial cells in the human body. Authors: Yoshihara M, Ohmiya H, Hara S, Kawasaki S, Hayashizaki Y, Itoh M, Kawaji H, Tsujikawa M, Nishida K PLoS ONE, 2015;10(3):e0117581. Species: Human Sample Type: Whole Tissue Application: IHC OCT-embedded An anti-inflammatory property of Candida albicans beta-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Authors: Smeekens S, Gresnigt M, Becker K, Cheng S, Netea S, Jacobs L, Jansen T, van de Veerdonk F, Williams D, Joosten L, Dinarello C, Netea M Cytokine, 2015;71(2):215-22. Species: Human Sample Type: Whole Cells Application: Neut Ctrl Spinal NF-kappaB and chemokine ligand 5 expression during spinal glial cell activation in a neuropathic pain model. Authors: Yin Q, Fan Q, Zhao Y, Cheng M, Liu H, Li J, Lu F, Jia J, Cheng W, Yan C PLoS ONE, 2015;10(1):e0115120. Species: Rat Sample Type: In Vivo Application: Neut Ctrl Increased Levels of Macrophage Inflammatory Proteins Result in Resistance to R5-Tropic HIV-1 in a Subset of Elite Controllers. Authors: Walker W, Kurscheid S, Joshi S, Lopez C, Goh G, Choi M, Barakat L, Francis J, Fisher A, Kozal M, Zapata H, Shaw A, Lifton R, Sutton R, Fikrig E J Virol, 2015;89(10):5502-14. Species: Human Sample Type: Whole Cells Application: Neut P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy. Authors: Wang H, Hong L, Huang J, Jiang Q, Tao R, Tan C, Lu N, Wang C, Ahmed M, Lu Y, Liu Z, Shi W, Lai E, Wilcox C, Han F Cell Res, 2015;25(6):674-90. Species: Mouse Sample Type: In Vivo Application: In vivo Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis. Authors: Bonapace L, Coissieux M, Wyckoff J, Mertz K, Varga Z, Junt T, Bentires-Alj M Nature, 2015;515(7525):130-3. Species: Mouse Sample Type: In Vivo High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirus. Authors: Scheuplein V, Seifried J, Malczyk A, Miller L, Hocker L, Vergara-Alert J, Dolnik O, Zielecki F, Becker B, Spreitzer I, Konig R, Becker S, Waibler Z, Muhlebach M J Virol, 2015;89(7):3859-69. Species: Human Sample Type: Whole Cells Application: Ctrl CD105 expression on CD34-negative spindle-shaped stromal cells of primary tumor is an unfavorable prognostic marker in early breast cancer patients. Authors: Martinez L, Labovsky V, Calcagno M, Davies K, Garcia Rivello H, Bianchi M, Wernicke A, Fernandez Vallone V, Chasseing N PLoS ONE, 2015;10(3):e0121421. Species: Human Sample Type: Whole Tissue Application: IHC Paraffin-embedded IL-1alpha signaling is critical for leukocyte recruitment after pulmonary Aspergillus fumigatus challenge. Authors: Caffrey A, Lehmann M, Zickovich J, Espinosa V, Shepardson K, Watschke C, Hilmer K, Thammahong A, Barker B, Rivera A, Cramer R, Obar J PLoS Pathog, 2015;11(1):e1004625. Species: Mouse Sample Type: In Vivo Application: In vivo Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts. Authors: Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G Br J Cancer, 2015;112(10):1675-86. Species: Human Sample Type: Whole Cells Application: Neut Ctrl Convergence of cMyc and beta-catenin on Tcf7l1 enables endoderm specification. Authors: Morrison G, Scognamiglio R, Trumpp A, Smith A EMBO J, 2015;35(3):356-68. Species: Mouse Sample Type: Cell Lysates Application: ChIP IL-4/CCL22/CCR4 axis controls regulatory T-cell migration that suppresses inflammatory bone loss in murine experimental periodontitis. Authors: Araujo-Pires A, Vieira A, Francisconi C, Biguetti C, Glowacki A, Yoshizawa S, Campanelli A, Trombone A, Sfeir C, Little S, Garlet G J Bone Miner Res, 2015;30(3):412-22. Species: Mouse Sample Type: In Vivo Application: Neut Ctrl Immature myeloid cells directly contribute to skin tumor development by recruiting IL-17-producing CD4+ T cells. Authors: Ortiz M, Kumar V, Martner A, Mony S, Donthireddy L, Condamine T, Seykora J, Knight S, Malietzis G, Lee G, Moorghen M, Lenox B, Luetteke N, Celis E, Gabrilovich D J Exp Med, 2015;212(3):351-67. Species: Mouse Sample Type: In Vivo Application: Neut Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice. Authors: Chien C, Lee M, Liou H, Liou H, Fu W PLoS ONE, 2015;10(2):e0115827. Species: Mouse Sample Type: In Vivo Application: In vivo The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity. Authors: Hoffmann F, Kuhn P, Laurent S, Hauck S, Berer K, Wendlinger S, Krumbholz M, Khademi M, Olsson T, Dreyling M, Pfister H, Alexander T, Hiepe F, Kumpfel T, Crawford H, Wekerle H, Hohlfeld R, Lichtenthaler S, Meinl E J Immunol, 2015;194(2):542-52. Species: Human Sample Type: Cell Culture Supernates Application: IP Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability. Authors: Hendel, Alon, Hsu, Ivy, Granville, David J Lab Invest, 2014;94(7):716-25. Species: Mouse Sample Type: In Vivo Application: Neut Ctrl The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Authors: Paolino, Magdalen, Choidas, Axel, Wallner, Stephani, Pranjic, Blanka, Uribesalgo, Iris, Loeser, Stefanie, Jamieson, Amanda M, Langdon, Wallace, Ikeda, Fumiyo, Fededa, Juan Pab, Cronin, Shane J, Nitsch, Roberto, Schultz-Fademrecht, Carsten, Eickhoff, Jan, Menninger, Sascha, Unger, Anke, Torka, Robert, Gruber, Thomas, Hinterleitner, Reinhard, Baier, Gottfrie, Wolf, Dominik, Ullrich, Axel, Klebl, Bert M, Penninger, Josef M Nature, 2014;507(7493):508-12. Species: Mouse Sample Type: Whole Cells Application: Flow Diversification of TAM receptor tyrosine kinase function. Authors: Zagorska A, Traves P, Lew E, Dransfield I, Lemke G Nat Immunol, 2014;15(10):920-8. Species: Mouse Sample Type: In Vivo Application: In vivo Brain glycolipids suppress T helper cells and inhibit autoimmune demyelination. Authors: Mycko M, Sliwinska B, Cichalewska M, Cwiklinska H, Raine C, Selmaj K J Neurosci, 2014;34(25):8646-58. Species: Mouse Sample Type: Whole Cells Application: Neut T cell-derived microvesicles induce mast cell production of IL-24: relevance to inflammatory skin diseases. Authors: Shefler I, Pasmanik-Chor M, Kidron D, Mekori Y, Hershko A J Allergy Clin Immunol, 2014;133(1):217-24.e1-3. Species: Human Sample Type: Whole Cells Application: Isotype control Cytoplasmic protein methylation is essential for neural crest migration. Authors: Vermillion K, Lidberg K, Gammill L J Cell Biol, 2014;204(1):95-109. Species: Chicken Sample Type: Cell Lysates Application: Neut Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia. Authors: Le D, Rochlitzer S, Fischer A, Heck S, Tschernig T, Sester M, Bals R, Welte T, Braun A, Dinh Q Respir Res, 2014;15(0):73. Species: Mouse Sample Type: Whole Tissue Application: IHC IL-27, targeting antigen-presenting cells, promotes Th17 differentiation and colitis in mice. Authors: Visperas A, Do J, Bulek K, Li X, Min B Mucosal Immunol, 2014;7(3):625-33. Species: Mouse Sample Type: Whole Cells Application: Bioassay Survival of neural stem cell grafts in the lesioned spinal cord is enhanced by a combination of treadmill locomotor training via insulin-like growth factor-1 signaling. Authors: Hwang D, Shin H, Kwon M, Choi J, Ryu B, Kim B J Neurosci, 2014;34(38):12788-800. Species: Rat Sample Type: In Vivo Application: In Vivo Quantitative analyses of retinal vascular area and density after different methods to reduce VEGF in a rat model of retinopathy of prematurity. Authors: Wang H, Yang Z, Jiang Y, Flannery J, Hammond S, Kafri T, Vemuri S, Jones B, Hartnett M Invest Ophthalmol Vis Sci, 2014;55(2):737-44. Species: Rat Sample Type: In Vivo Application: contorl Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients. Authors: Haga E, Endo Y, Haruta M, Koba C, Matsumura K, Takamatsu K, Ikeda T, Nishimura Y, Senju S J Immunol, 2014;193(4):2024-33. Species: Mouse Sample Type: Whole Cells Application: Flow Effect of thrombin on human amnion mesenchymal cells, mouse fetal membranes, and preterm birth. Authors: Mogami, Haruta, Keller, Patrick, Shi, Haolin, Word, R Ann J Biol Chem, 2014;289(19):13295-307. Species: Human Sample Type: Cell Lysates Application: Neut Ctrl Galectin-7 acts as an adhesion molecule during implantation and increased expression is associated with miscarriage. Authors: Menkhorst E, Gamage T, Cuman C, Kaitu'u-Lino T, Tong S, Dimitriadis E Placenta, 2014;35(3):195-201. Species: Human Sample Type: Whole Tissue Application: IHC Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta. Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y Am J Physiol Endocrinol Metab, 2014;307(2):E186-98. Species: Mouse Sample Type: In Vivo Application: In vivo Let-7d suppresses growth, metastasis, and tumor macrophage infiltration in renal cell carcinoma by targeting COL3A1 and CCL7. Authors: Su, Boxing, Zhao, Wei, Shi, Bentao, Zhang, Zhongyua, Yu, Xi, Xie, Feng, Guo, Zhongqia, Zhang, Xiaoyu, Liu, Jin, Shen, Qi, Wang, Jinghua, Li, Xuesong, Zhang, Zhiqian, Zhou, Liqun Mol Cancer, 2014;13(0):206. Species: Human Sample Type: Whole Cells Application: Neut Ctrl Microglia enhance neurogenesis and oligodendrogenesis in the early postnatal subventricular zone. Authors: Shigemoto-Mogami Y, Hoshikawa K, Goldman J, Sekino Y, Sato K J Neurosci, 2014;34(6):2231-43. Species: Rat Sample Type: Whole Cells Application: Neut Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K Nat Med, 2014;20(4):377-84. Species: Mouse Sample Type: Whole Cells Application: Bioassay - Ctrl Carbonic anhydrase IV is expressed on IL-5-activated murine eosinophils. Authors: Wen T, Mingler M, Wahl B, Khorki M, Pabst O, Zimmermann N, Rothenberg M J Immunol, 2014;192(12):5481-9. Species: Mouse Sample Type: Whole Tissue Application: IHC Paraffin-embedded The role of host and microbial factors in the pathogenesis of pneumococcal bacteraemia arising from a single bacterial cell bottleneck. Authors: Gerlini A, Colomba L, Furi L, Braccini T, Manso A, Pammolli A, Wang B, Vivi A, Tassini M, Van Rooijen N, Pozzi G, Ricci S, Andrew P, Koedel U, Moxon E, Oggioni M PLoS Pathog, 2014;10(3):e1004026. Species: Mouse Sample Type: Whole Cells Application: Flow Lymphotoxin beta receptor signaling induces IL-8 production in human bronchial epithelial cells. Authors: Mikami Y, Matsuzaki H, Horie M, Noguchi S, Jo T, Narumoto O, Kohyama T, Takizawa H, Nagase T, Yamauchi Y PLoS ONE, 2014;9(12):e114791. Species: Human Sample Type: Cell Lysates Application: Isotype control Attenuation of intestinal inflammation in interleukin-10-deficient mice infected with Citrobacter rodentium. Authors: Dann, Sara M, Le, Christin, Choudhury, Barun K, Liu, Houpu, Saldarriaga, Omar, Hanson, Elaine M, Cong, Yingzi, Eckmann, Lars Infect Immun, 2014;82(5):1949-58. Species: Mouse Sample Type: In Vivo Application: Neut Ctrl IL-9 regulates allergen-specific Th1 responses in allergic contact dermatitis. Authors: Liu J, Harberts E, Tammaro A, Girardi N, Filler R, Fishelevich R, Temann A, Licona-Limon P, Girardi M, Flavell R, Gaspari A J Invest Dermatol, 2014;134(7):1903-11. Species: Human Sample Type: Whole Cells Application: Neut Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies. Authors: Yang, Guang, Holl, T Matt, Liu, Yang, Li, Yi, Lu, Xiaozhi, Nicely, Nathan I, Kepler, Thomas B, Alam, S Munir, Liao, Hua-Xin, Cain, Derek W, Spicer, Leonard, VandeBerg, John L, Haynes, Barton F, Kelsoe, Garnett J Exp Med, 2013;210(2):241-56. Species: Human Sample Type: Whole Cells Application: IF Tricyclic antidepressant amitriptyline indirectly increases the proliferation of adult dentate gyrus-derived neural precursors: an involvement of astrocytes. Authors: Boku, Shuken, Hisaoka-Nakashima, Kazue, Nakagawa, Shin, Kato, Akiko, Kajitani, Naoto, Inoue, Takeshi, Kusumi, Ichiro, Takebayashi, Minoru PLoS ONE, 2013;8(11):e79371. Species: Rat Sample Type: Whole Cells Application: Neut Ctrl CCR6 is required for epidermal trafficking of gammadelta-T cells in an IL-23-induced model of psoriasiform dermatitis. Authors: Mabuchi T, Singh T, Takekoshi T, Jia G, Wu X, Kao M, Weiss I, Farber J, Hwang S J Invest Dermatol, 2013;133(1):164-71. Species: Mouse Sample Type: Whole Tissue Application: IHC Frozen A role for PVRL4-driven cell-cell interactions in tumorigenesis. Authors: Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, Elledge S Elife, 2013;2(0):e00358. Species: Human Sample Type: Whole Cells Application: Bioassay Interleukin-33 and alveolar macrophages contribute to the mechanisms underlying the exacerbation of IgE-mediated airway inflammation and remodelling in mice. Authors: Mizutani N, Nabe T, Yoshino S Immunology, 2013;139(2):205-18. Species: Mouse Sample Type: In Vivo Application: Isotype control Blimp1 (Prdm1) prevents re-specification of photoreceptors into retinal bipolar cells by restricting competence. Authors: Brzezinski J, Uoon Park K, Reh T Dev Biol, 2013;384(2):194-204. Species: Mouse Sample Type: Tissue Homogenates Application: IP Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells. Authors: Loebbermann, Jens, Durant, Lydia, Thornton, Hannah, Johansson, Cecilia, Openshaw, Peter J Proc Natl Acad Sci U S A, 2013;110(8):2987-92. Species: Mouse Sample Type: In Vivo Application: Neut Mast cells contribute to double-stranded RNA-induced augmentation of airway eosinophilia in a murine model of asthma. Authors: Kan-o K, Matsunaga Y, Fukuyama S, Moriwaki A, Hirai-Kitajima H, Yokomizo T, Aritake K, Urade Y, Nakanishi Y, Inoue H, Matsumoto K Respir Res, 2013;14(0):28. Species: Mouse Sample Type: Whole Cells Application: Flow Lack of oncostatin M receptor beta leads to adipose tissue inflammation and insulin resistance by switching macrophage phenotype. Authors: Komori T, Tanaka M, Senba E, Miyajima A, Morikawa Y J Biol Chem, 2013;288(30):21861-75. Species: Mouse Sample Type: Whole Cells Application: Flow Ctrl NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma. Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S PLoS ONE, 2013;8(11):e78728. Application: Isotype control Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice. Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R J Biol Chem, 2013;288(3):1953-66. Species: Human Sample Type: Whole Cells Application: Neut Ctrl Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma. Authors: Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, Ruan J, Xia L Cancer Res, 2013;73(24):7254-64. Species: Mouse Sample Type: Whole Cells Application: Neut Ctrl The CD8-derived chemokine XCL1/lymphotactin is a conformation-dependent, broad-spectrum inhibitor of HIV-1. Authors: Guzzo C, Fox J, Lin Y, Miao H, Cimbro R, Volkman B, Fauci A, Lusso P PLoS Pathog, 2013;9(12):e1003852. Species: Human Sample Type: Recombinant Protein Application: Co-immunoprecipitation Peptide inhibitor of CXCL4-CCL5 heterodimer formation, MKEY, inhibits experimental aortic aneurysm initiation and progression. Authors: Iida, Yasunori, Xu, Baohui, Xuan, Haojun, Glover, Keith J, Tanaka, Hiroki, Hu, Xiaolei, Fujimura, Naoki, Wang, Wei, Schultz, Joshua R, Turner, Court R, Dalman, Ronald L Arterioscler Thromb Vasc Biol, 2013;33(4):718-26. Species: Mouse Sample Type: Whole Tissue Application: IHC Chemokine 25-induced signaling suppresses colon cancer invasion and metastasis. J. Clin. Invest., 2012;122(9):3184-96. Species: Mouse Sample Type: In Vivo Application: In vivo control The adaptation of the blood-brain barrier to vascular endothelial growth factor and placental growth factor during pregnancy. Authors: Schreurs MP, Houston EM, May V, Cipolla MJ FASEB J., 2012;26(1):355-62. Species: Rat Sample Type: In Vivo Application: Ctrl Galectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling. Authors: Diskin S, Chen WS, Cao Z, Gyawali S, Gong H, Soza A, Gonzalez A, Panjwani N PLoS ONE, 2012;7(9):e44400. Species: Human Sample Type: Whole Tissue Application: Ctrl Cytomegalovirus impairs cytotrophoblast-induced lymphangiogenesis and vascular remodeling in an in vivo human placentation model. Authors: Tabata T, Petitt M, Fang-Hoover J, Rivera J, Nozawa N, Shiboski S, Inoue N, Pereira L Am J Pathol, 2012;181(5):1540-59. Species: Human Sample Type: Whole Cells Application: Ctrl Transforming growth factor Beta 3 is required for excisional wound repair in vivo. Authors: Le M, Naridze R, Morrison J, Biggs L, Rhea L, Schutte B, Kaartinen V, Dunnwald M PLoS ONE, 2012;7(10):e48040. Species: Mouse Sample Type: In Vivo Application: Ctrl Leukemia inhibitory factor signaling is required for lung protection during pneumonia. Authors: Quinton LJ, Mizgerd JP, Hilliard KL J. Immunol., 2012;188(12):6300-8. Species: Mouse Sample Type: In Vivo Application: Ctrl FcgammaRI mediates serum amyloid P inhibition of fibrocyte differentiation. Authors: Crawford J, Pilling D, Gomer R J Leukoc Biol, 2012;92(4):699-711. Species: Human Sample Type: Whole Cells Application: Ctrl The pulmonary endothelial glycocalyx regulates neutrophil adhesion and lung injury during experimental sepsis. Nat. Med., 2012;18(0):1217. Species: Mouse Sample Type: Whole Tissue Application: Ctrl Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function. Authors: Langer, Marybeth, Duggan, Elizabet, Booth, John Lel, Patel, Vineet I, Zander, Ryan A, Silasi-Mansat, Robert, Ramani, Vijay, Veres, Tibor Zo, Prenzler, Frauke, Sewald, Katherin, Williams, Daniel M, Coggeshall, Kenneth, Awasthi, Shanjana, Lupu, Florea, Burian, Dennis, Ballard, Jimmy Da, Braun, Armin, Metcalf, Jordan P Infect Immun, 2012;80(12):4374-87. Species: Human Sample Type: Whole Cells Application: Ctrl Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc. Authors: Sakai, Daisuke, Nakamura, Yoshihik, Nakai, Tomoko, Mishima, Taishi, Kato, Shunichi, Grad, Sibylle, Alini, Mauro, Risbud, Makarand, Chan, Danny, Cheah, Kathryn, Yamamura, Ken-ichi, Masuda, Koichi, Okano, Hideyuki, Ando, Kiyoshi, Mochida, Joji Nat Commun, 2012;3(0):1264. Species: Human Sample Type: Whole Cells Application: Bioassay Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy. Authors: Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, Tesniere A, Ibrahim N, Dechanet-Merville J, Chaput N, Smyth MJ, Kroemer G, Zitvogel L J. Exp. Med., 2011;208(3):491-503. Species: Mouse Sample Type: Whole Cells Application: Isotype control Th17 cells induce ectopic lymphoid follicles in central nervous system tissue inflammation. Authors: Peters A, Pitcher LA, Sullivan JM, Mitsdoerffer M, Acton SE, Franz B, Wucherpfennig K, Turley S, Carroll MC, Sobel RA, Bettelli E, Kuchroo VK Immunity, 2011;35(6):986-96. Species: Mouse Sample Type: In Vivo Application: Ctrl Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling. Authors: Tesio M, Golan K, Corso S Blood, 2011;117(2):419-28. Species: Mouse Sample Type: In Vivo Application: Ctrl The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Authors: Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Despres S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T Nature, 2011;477(7362):90-4. Species: Mouse Sample Type: Whole Cells Application: Ctrl Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virus. Authors: Noyce RS, Bondre DG, Ha MN PLoS Pathog., 2011;7(8):e1002240. Species: Hamster Sample Type: Whole Cells Application: Ctrl IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression. Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE J. Immunol., 2011;186(4):2613-22. Species: Mouse Sample Type: Whole Tissue Application: Ctrl Inhibitory actions of Anti-Mullerian Hormone (AMH) on ovarian primordial follicle assembly. Authors: Nilsson EE, Schindler R, Savenkova MI, Skinner MK PLoS ONE, 2011;6(5):e20087. Species: Rat Sample Type: Whole Tissue Application: Ctrl The immune-modulating cytokine and endogenous Alarmin interleukin-33 is upregulated in skin exposed to inflammatory UVB radiation. Authors: Byrne SN, Beaugie C, O'Sullivan C, Leighton S, Halliday GM Am. J. Pathol., 2011;179(1):211-22. Species: Human Sample Type: Whole Tissue Application: Ctrl Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells. Authors: Yamakawa N, Uchida T, Matthay MA, Makita K Am. J. Physiol. Lung Cell Mol. Physiol., 2011;300(4):L516-25. Species: Rat Sample Type: Whole Cells Application: Ctrl Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype. Authors: Ouwehand K, Oosterhoff D, Breetveld M J. Invest. Dermatol., 2011;131(2):418-25. Species: Human Sample Type: Whole Tissue Application: Ctrl Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth. Authors: Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E Nat. Med., 2011;17(11):1498-503. Species: Mouse Sample Type: In Vivo Application: Ctrl Relationship between complement membrane attack complex, chemokine (C-C motif) ligand 2 (CCL2) and vascular endothelial growth factor in mouse model of laser-induced choroidal neovascularization. Authors: Liu J, Jha P, Lyzogubov VV, Tytarenko RG, Bora NS, Bora PS J. Biol. Chem., 2011;286(23):20991-1001. Species: Mouse Sample Type: In Vivo Application: Ctrl Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma. Authors: Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C PLoS Pathog., 2011;7(4):e1002016. Species: Human Sample Type: Whole Cells Application: Ctrl Paternal recognition of adult offspring mediated by newly generated CNS neurons. Authors: Mak GK, Weiss S, Nat. Neurosci., 2010;13(6):753-8. Species: Mouse Sample Type: In Vivo Application: Ctrl Interleukin-1beta mediates the extra-intestinal thrombosis associated with experimental colitis. Authors: Yoshida H, Russell J, Senchenkova EY, Almeida Paula LD, Granger DN Am. J. Pathol., 2010;177(6):2774-81. Species: Mouse Sample Type: In Vivo Application: Ctrl IL-33 is produced by mast cells and regulates IgE-dependent inflammation. Authors: Hsu CL, Neilsen CV, Bryce PJ PLoS ONE, 2010;5(8):e11944. Species: Mouse Sample Type: Whole Cells Application: Ctrl Chemerin peptides promote phagocytosis in a ChemR23- and Syk-dependent manner. Authors: Cash JL, Christian AR, Greaves DR J. Immunol., 2010;184(9):5315-24. Species: Mouse Sample Type: In Vivo Application: Ctrl A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa. Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW Mucosal Immunol, 2010;3(1):40-8. Species: Mouse Sample Type: Whole Tissue Application: Ctrl Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells. Authors: Eidenschenk C, Crozat K, Krebs P, Arens R, Popkin D, Arnold CN, Blasius AL, Benedict CA, Moresco EM, Xia Y, Beutler B Proc. Natl. Acad. Sci. U.S.A., 2010;107(21):9759-64. Species: Mouse Sample Type: In Vivo Application: Ctrl Thymic stromal lymphopoietin contributes to myeloid hyperplasia and increased immunoglobulins, but not epidermal hyperplasia, in RabGEF1-deficient mice. Authors: Tsai M, Chen CC, Mukai K Am. J. Pathol., 2010;177(5):2411-20. Species: Mouse Sample Type: Whole Tissue Application: Ctrl GAS6/Mer axis regulates the homing and survival of the E2A/PBX1-positive B-cell precursor acute lymphoblastic leukemia in the bone marrow niche. Authors: Shiozawa Y, Pedersen EA, Taichman RS Exp. Hematol., 2010;38(2):132-40. Species: Human Sample Type: Whole Cells Application: Ctrl Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation. Authors: Reikvam H, Hatfield KJ, Oyan AM, Kalland KH, Kittang AO, Bruserud O Eur. J. Haematol., 2010;84(3):239-51. Species: Human Sample Type: Whole Cells Application: Ctrl IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells. Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM Brain Behav. Immun., 2010;0(0):. Species: Human Sample Type: Whole Cells Application: Ctrl Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. Authors: Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME J. Allergy Clin. Immunol., 2010;125(4):879-888. Species: Human Sample Type: Whole Tissue Application: Ctrl The B-cell tumor-associated antigen ROR1 can be targeted with T cells modified to express a ROR1-specific chimeric antigen receptor. Authors: Hudecek M, Schmitt TM, Baskar S Blood, 2010;116(22):4532-41. Species: Human Sample Type: Whole Cells Application: Ctrl Patched1 inhibits epidermal progenitor cell expansion and basal cell carcinoma formation by limiting Igfbp2 activity. Authors: Villani RM, Adolphe C, Palmer J, Waters MJ, Wainwright BJ Cancer Prev Res (Phila), 2010;3(10):1222-34. Species: Mouse Sample Type: Whole Tissue Application: Ctrl Stromal MCP-1 in mammary tumors induces tumor-associated macrophage infiltration and contributes to tumor progression. Authors: Fujimoto H, Sangai T, Ishii G, Ikehara A, Nagashima T, Miyazaki M, Ochiai A Int. J. Cancer, 2009;125(6):1276-84. Species: Mouse Sample Type: In Vivo Application: Ctrl Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production. Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ Proc. Natl. Acad. Sci. U.S.A., 2009;106(14):5954-9. Species: Mouse Sample Type: In Vivo Application: Ctrl Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway. Authors: Weng TI, Wu HY, Lin PY, Liu SH Infect. Immun., 2009;77(8):3312-9. Species: Mouse Sample Type: In Vivo Application: Ctrl CCR7-CCL19/CCL21-regulated dendritic cells are responsible for effectiveness of sublingual vaccination. Authors: Song JH, Kim JI, Kwon HJ, Shim DH, Parajuli N, Cuburu N, Czerkinsky C, Kweon MN J. Immunol., 2009;182(11):6851-60. Species: Mouse Sample Type: In Vivo Application: Ctrl Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells. Authors: Brounais B, David E, Chipoy C, Trichet V, Ferre V, Charrier C, Duplomb L, Berreur M, Redini F, Heymann D, Blanchard F Bone, 2009;44(5):830-9. Species: Mouse Sample Type: Cell Lysates Application: Ctrl Vascular endothelial growth factor-induced chemotaxis and IL-10 from T cells. Authors: Shin JY, Yoon IH, Kim JS, Kim B, Park CG Cell. Immunol., 2009;256(1):72-8. Species: Mouse Sample Type: Whole Cells Application: Ctrl The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis. Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R Eur. J. Immunol., 2009;39(12):3570-81. Species: Human Sample Type: Whole Cells Application: Ctrl Salmonella disrupts lymph node architecture by TLR4-mediated suppression of homeostatic chemokines. Authors: St John AL, Abraham SN Nat. Med., 2009;15(11):1259-65. Species: Mouse Sample Type: In Vivo Application: Ctrl Atropine-enhanced, antigen challenge-induced airway hyperreactivity in guinea pigs is mediated by eosinophils and nerve growth factor. Authors: Verbout NG, Jacoby DB, Gleich GJ, Fryer AD Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L228-37. Species: Guinea Pig Sample Type: In Vivo Application: Ctrl Leptin derived from adipocytes in injured peripheral nerves facilitates development of neuropathic pain via macrophage stimulation. Authors: Maeda T, Kiguchi N, Kobayashi Y, Ikuta T, Ozaki M, Kishioka S Proc. Natl. Acad. Sci. U.S.A., 2009;106(31):13076-81. Species: Mouse Sample Type: In Vivo Application: Ctrl Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha. Authors: Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, Wang P, Messina JL Endocrinology, 2008;149(5):2369-82. Species: Rat Sample Type: In Vivo Application: Ctrl Mature antigen-experienced T helper cells synthesize and secrete the B cell chemoattractant CXCL13 in the inflammatory environment of the rheumatoid joint. Arthritis Rheum., 2008;58(0):3377-87. Species: Human Sample Type: Whole Tissue Application: Ctrl Matrix metalloproteinase 8 contributes to solubilization of IL-13 receptor alpha2 in vivo. Authors: Chen W, Tabata Y, Gibson AM, Daines MO, Warrier MR, Wills-Karp M, Hershey GK J. Allergy Clin. Immunol., 2008;122(3):625-32. Species: Mouse Sample Type: Whole Cells Application: Ctrl CXCL12 is essential for migration of activated Langerhans cells from epidermis to dermis. Authors: Ouwehand K, Santegoets SJ, Bruynzeel DP, Scheper RJ, de Gruijl TD, Gibbs S Eur. J. Immunol., 2008;38(11):3050-9. Species: Human Sample Type: Ex Vivo Application: Ctrl Regulation of scar formation by vascular endothelial growth factor. Authors: Wilgus TA, Ferreira AM, Oberyszyn TM, Bergdall VK, DiPietro LA Lab. Invest., 2008;88(6):579-90. Species: Mouse Sample Type: In Vivo Application: Ctrl Fibroblast-type reticular stromal cells regulate the lymph node vasculature. Authors: Chyou S, Ekland EH, Carpenter AC, Tzeng TC, Tian S, Michaud M, Madri JA, Lu TT J. Immunol., 2008;181(6):3887-96. Species: Mouse Sample Type: In Vivo Application: Ctrl Neural-activity-dependent release of S100B from astrocytes enhances kainate-induced gamma oscillations in vivo. Authors: Sakatani S, Seto-Ohshima A, Shinohara Y, Yamamoto Y, Yamamoto H, Itohara S, Hirase H J. Neurosci., 2008;28(43):10928-36. Species: Mouse Sample Type: In Vivo Application: Ctrl The secretory leukocyte protease inhibitor (SLPI) and the secondary granule protein lactoferrin are synthesized in myelocytes, colocalize in subcellular fractions of neutrophils, and are coreleased by activated neutrophils. Authors: Jacobsen LC, Sorensen OE, Cowland JB, Borregaard N, Theilgaard-Monch K J. Leukoc. Biol., 2008;83(5):1155-64. Species: Human Sample Type: Whole Cells Application: Ctrl Overexpression of CXCL16 and its receptor CXCR6/Bonzo promotes growth of human schwannomas. Authors: Held-Feindt J, Rehmke B, Mentlein R, Hattermann K, Knerlich F, Hugo HH, Ludwig A, Mehdorn HM Glia, 2008;56(7):764-74. Species: Human Sample Type: Whole Cells Application: Ctrl The critical role of invading peripheral macrophage-derived interleukin-6 in vincristine-induced mechanical allodynia in mice. Authors: Kiguchi N, Maeda T, Kobayashi Y, Kondo T, Ozaki M, Kishioka S Eur. J. Pharmacol., 2008;592(1):87-92. Species: Mouse Sample Type: In Vivo Application: Ctrl BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. Authors: Jeanpierre S, Nicolini FE, Kaniewski B, Dumontet C, Rimokh R, Puisieux A, Maguer-Satta V Blood, 2008;112(8):3154-63. Species: Human Sample Type: Whole Cells Application: Ctrl Role of VEGF in maintaining renal structure and function under normotensive and hypertensive conditions. Authors: Advani A, Kelly DJ, Advani SL, Cox AJ, Thai K, Zhang Y, White KE, Gow RM, Marshall SM, Steer BM, Marsden PA, Rakoczy PE, Gilbert RE Proc. Natl. Acad. Sci. U.S.A., 2007;104(36):14448-53. Species: Rat Sample Type: In Vivo Application: Ctrl 12-O-tetradecanoyl phorbol 13-acetate induces the expression of B7-DC, -H1, -H2, and -H3 in K562 cells. Authors: Jang BC, Park YK, Choi IH, Kim SP, Hwang JB, Baek WK, Suh MH, Mun KC, Suh SI Int. J. Oncol., 2007;31(6):1439-47. Species: Human Sample Type: Whole Cells Application: Ctrl IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. Authors: Gleissner CA, Zastrow A, Klingenberg R, Kluger MS, Konstandin M, Celik S, Haemmerling S, Shankar V, Giese T, Katus HA, Dengler TJ Eur. J. Immunol., 2007;37(1):177-92. Species: Human Sample Type: Whole Cells Application: Ctrl IL-2 is essential for TGF-beta to convert naive CD4+CD25- cells to CD25+Foxp3+ regulatory T cells and for expansion of these cells. Authors: Zheng SG, Wang J, Wang P, Gray JD, Horwitz DA J. Immunol., 2007;178(4):2018-27. Species: Mouse Sample Type: Whole Cells Application: Ctrl Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation. Authors: Chandrasekar B, Patel DN, Mummidi S, Kim JW, Clark RA, Valente AJ J. Biol. Chem., 2007;283(7):4200-9. Species: Mouse Sample Type: Cell Culture Supernates Application: Ctrl Osteopontin has a crucial role in allergic airway disease through regulation of dendritic cell subsets. Authors: Xanthou G, Alissafi T, Semitekolou M, Simoes DC, Economidou E, Gaga M, Lambrecht BN, Lloyd CM, Panoutsakopoulou V Nat. Med., 2007;13(5):570-8. Bv8 regulates myeloid-cell-dependent tumour angiogenesis. Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N Nature, 2007;450(7171):825-31. Species: Mouse Sample Type: Cell Lysates Application: Ctrl Erythropoietin promotes survival of retinal ganglion cells in DBA/2J glaucoma mice. Authors: Zhong L, Bradley J, Schubert W, Ahmed E, Adamis AP, Shima DT, Robinson GS, Ng YS Invest. Ophthalmol. Vis. Sci., 2007;48(3):1212-8. Species: Mouse Sample Type: Whole Tissue Application: Ctrl The C-type lectin receptors CLEC-2 and Dectin-1, but not DC-SIGN, signal via a novel YXXL-dependent signaling cascade. Authors: Fuller GL, Williams JA, Tomlinson MG, Eble JA, Hanna SL, Pohlmann S, Suzuki-Inoue K, Ozaki Y, Watson SP, Pearce AC J. Biol. Chem., 2007;282(17):12397-409. Species: Chicken Sample Type: Whole Cells Application: Ctrl CD163 expression confers susceptibility to porcine reproductive and respiratory syndrome viruses. Authors: Calvert JG, Slade DE, Shields SL, Jolie R, Mannan RM, Ankenbauer RG, Welch SK J. Virol., 2007;81(14):7371-9. Species: Primate - Macaca mulatta (Rhesus Macaque) Sample Type: Whole Cells Application: Ctrl Vascular-derived artemin: a determinant of vascular sympathetic innervation? Authors: Damon DH, Teriele JA, Marko SB Am. J. Physiol. Heart Circ. Physiol., 2007;293(1):H266-73. Species: Rat Sample Type: Whole Cells Application: Ctrl Amelioration of coxsackievirus B3-mediated myocarditis by inhibition of tissue inhibitors of matrix metalloproteinase-1. Authors: Crocker SJ, Frausto RF, Whitmire JK, Benning N, Milner R, Whitton JL Am. J. Pathol., 2007;171(6):1762-73. Species: Mouse Sample Type: In Vivo Application: Ctrl Wnt-induced secreted protein-1 is a prohypertrophic and profibrotic growth factor. Authors: Colston JT, de la Rosa SD, Koehler M, Gonzales K, Mestril R, Freeman GL, Bailey SR, Chandrasekar B Am. J. Physiol. Heart Circ. Physiol., 2007;293(3):H1839-46. Species: Rat Sample Type: Whole Cells Application: Ctrl Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxia. Authors: Yeh WL, Lin CJ, Fu WM Mol. Pharmacol., 2007;73(1):170-7. Species: Rat Sample Type: Whole Cells Application: Ctrl Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage. Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH J. Mol. Cell. Cardiol., 2007;42(3):620-30. Species: Rat Sample Type: Application: Ctrl Inhibition of spinal microglial cathepsin S for the reversal of neuropathic pain. Authors: Clark AK, Yip PK, Grist J, Gentry C, Staniland AA, Marchand F, Dehvari M, Wotherspoon G, Winter J, Ullah J, Bevan S, Malcangio M Proc. Natl. Acad. Sci. U.S.A., 2007;104(25):10655-60. Species: Rat Sample Type: In Vivo Application: Ctrl T cell-dependent survival of CD20+ and CD20- plasma cells in human secondary lymphoid tissue. Authors: Withers DR, Fiorini C, Fischer RT, Ettinger R, Lipsky PE, Grammer AC Blood, 2007;109(11):4856-64. Species: Human Sample Type: Whole Cells Application: Ctrl The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation. Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K Crit. Care Med., 2007;35(9):2156-63. Species: Mouse Sample Type: In Vivo Application: Ctrl Bronchial epithelial cell growth regulation in fibroblast cocultures: the role of hepatocyte growth factor. Authors: Skibinski G, Elborn JS, Ennis M Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(1):L69-76. Species: Human Sample Type: Whole Cells Application: Ctrl Distribution of the receptor for advanced glycation end products in the human male reproductive tract: prevalence in men with diabetes mellitus. Authors: Mallidis C, Agbaje I, Rogers D, Glenn J, McCullough S, Atkinson AB, Steger K, Stitt A, McClure N Hum. Reprod., 2007;22(8):2169-77. Species: Human Sample Type: Whole Tissue Application: Ctrl Pleiotrophin is highly expressed by myeloma cells and promotes myeloma tumor growth. Authors: Chen H, Gordon MS, Campbell RA, Li M, Wang CS, Lee HJ, Sanchez E, Manyak SJ, Gui D, Shalitin D, Said J, Chang Y, Deuel TF, Baritaki S, Bonavida B, Berenson JR Blood, 2007;110(1):287-95. Species: Human Sample Type: Whole Cells Application: Ctrl Innate immune responses to herpes simplex virus type 2 influence skin homing molecule expression by memory CD4+ lymphocytes. Authors: Koelle DM, Huang J, Hensel MT, McClurkan CL J. Virol., 2006;80(6):2863-72. Species: Human Sample Type: Whole Cells Application: Ctrl CCL2 regulates angiogenesis via activation of Ets-1 transcription factor. Authors: Stamatovic SM, Keep RF, Mostarica-Stojkovic M, Andjelkovic AV J. Immunol., 2006;177(4):2651-61. Species: Mouse Sample Type: Whole Cells Application: Ctrl Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation. Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS Exp. Cell Res., 2006;312(10):1909-23. Species: Human Sample Type: Whole Cells Application: Ctrl Mechanism of IL-6-mediated cardiac dysfunction following trauma-hemorrhage. Authors: Yang S, Hu S, Hsieh YC, Choudhry MA, Rue LW, Bland KI, Chaudry IH J. Mol. Cell. Cardiol., 2006;40(4):570-9. Species: Rat Sample Type: Application: Ctrl Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. Authors: Li Y, Fan J, Chen M, Li W, Woodley DT J. Invest. Dermatol., 2006;126(9):2096-105. Species: Human Sample Type: Serum Application: Ctrl TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells. Authors: Patel DN, Bailey SR, Gresham JK, Schuchman DB, Shelhamer JH, Goldstein BJ, Foxwell BM, Stemerman MB, Maranchie JK, Valente AJ, Mummidi S, Chandrasekar B Biochem. Biophys. Res. Commun., 2006;347(4):1113-20. Species: Human Sample Type: Whole Cells Application: Ctrl Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha. Authors: Daryadel A, Grifone RF, Simon HU, Yousefi S J. Biol. Chem., 2006;281(37):27653-61. Species: Human Sample Type: Whole Cells Application: Ctrl Induction of interleukin-6 by hepatitis C virus core protein in hepatitis C-associated mixed cryoglobulinemia and B-cell non-Hodgkin's lymphoma. Authors: Feldmann G, Nischalke HD, Nattermann J, Banas B, Berg T, Teschendorf C, Schmiegel W, Duhrsen U, Halangk J, Iwan A, Sauerbruch T, Caselmann WH, Spengler U Clin. Cancer Res., 2006;12(15):4491-8. Species: Human Sample Type: Whole Cells Application: Ctrl Mast cells facilitate local VEGF release as an early event in the pathogenesis of postoperative peritoneal adhesions. Authors: Cahill RA, Wang JH, Soohkai S, Redmond HP Surgery, 2006;140(1):108-12. Species: Mouse Sample Type: In Vivo Application: Ctrl Junctional adhesion molecule 1 is a functional receptor for feline calicivirus. Authors: Makino A, Shimojima M, Miyazawa T, Kato K, Tohya Y, Akashi H J. Virol., 2006;80(9):4482-90. Species: Human Sample Type: Whole Cells Application: Ctrl Type I and type II interferons delay human neutrophil apoptosis via activation of STAT3 and up-regulation of cellular inhibitor of apoptosis 2. Authors: Sakamoto E, Hato F, Kato T, Sakamoto C, Akahori M, Hino M, Kitagawa S J. Leukoc. Biol., 2005;78(1):301-9. Species: Human Sample Type: Whole Cells Application: Ctrl Variation in macrophage-migration-inhibitory-factor immunoreactivity during porcine gestation. Authors: Paulesu L, Cateni C, Romagnoli R, Ietta F, Dantzer V Biol. Reprod., 2005;72(4):949-53. Species: Human Sample Type: Whole Tissue Application: Ctrl Immunosuppressive effects of CCL17 on pulmonary antifungal responses during pulmonary invasive aspergillosis. Authors: Carpenter KJ, Hogaboam CM Infect. Immun., 2005;73(11):7198-207. Species: Mouse Sample Type: Application: Ctrl Maladaptive role of IL-6 in ischemic acute renal failure. Authors: Kielar ML, John R, Bennett M J. Am. Soc. Nephrol., 2005;16(11):3315-25. Species: Mouse Sample Type: In Vivo Application: Ctrl Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses. Authors: Gould WR, Baxi SM, Schroeder R, Peng YW, Leadley RJ, Peterson JT, Perrin LA J. Thromb. Haemost., 2005;3(4):733-41. Species: Human Sample Type: Whole Cells Application: Neut The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. Authors: Puxeddu I, Bader R, Piliponsky AM, Reich R, Levi-Schaffer F, Berkman N J. Allergy Clin. Immunol., 2005;117(1):103-10. Species: Human Sample Type: Whole Cells Application: Ctrl Requirement for intercellular adhesion molecule 1 and caveolae in invasion of human oral epithelial cells by Porphyromonas gingivalis. Authors: Tamai R, Asai Y, Ogawa T Infect. Immun., 2005;73(10):6290-8. Species: Human Sample Type: Whole Cells Application: Ctrl IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. Authors: Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, Hishinuma T, Goto J, Lotze MT, Kolls JK, Sasaki H J. Immunol., 2005;175(9):6177-89. Species: Human Sample Type: Whole Tissue Application: Ctrl Protection of human conjunctival fibroblasts from NO-induced apoptosis by interleukin-4 or interleukin-13. Authors: Fujitsu Y, Fukuda K, Kimura K, Seki K, Kumagai N, Nishida T Invest. Ophthalmol. Vis. Sci., 2005;46(3):797-802. Species: Human Sample Type: Whole Cells Application: Flow Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism. Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D J. Immunol., 2005;174(4):2376-86. Species: Human Sample Type: Whole Cells Application: Ctrl Heparin-binding EGF-like growth factor regulates human extravillous cytotrophoblast development during conversion to the invasive phenotype. Authors: Leach RE, Kilburn B, Wang J, Liu Z, Romero R, Armant DR Dev. Biol., 2004;266(2):223-37. Species: Human Sample Type: Whole Cells Application: Ctrl Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10. Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA J. Immunol., 2004;172(9):5213-21. Species: Human Sample Type: Whole Cells Application: Ctrl Inhibition of human immunodeficiency virus type 1 replication by Z-100, an immunomodulator extracted from human-type tubercle bacilli, in macrophages. Authors: Emori Y, Ikeda T, Ohashi T, Masuda T, Kurimoto T, Takei M, Kannagi M J. Gen. Virol., 2004;85(0):2603-13. Species: Human Sample Type: Whole Cells Application: Neut Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates. Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ J. Immunol., 2004;172(9):5753-64. Species: Primate - Macaca mulatta (Rhesus Macaque) Sample Type: Whole Cells Application: Ctrl Interleukin 11 advances progesterone-induced decidualization of human endometrial stromal cells. Authors: Dimitriadis E, Robb L, Salamonsen LA Mol. Hum. Reprod., 2002;8(7):636-43. Species: Human Sample Type: Whole Cells Application: Ctrl Stromal-derived factor 1 inhibits the cycling of very primitive human hematopoietic cells in vitro and in NOD/SCID mice. Authors: Cashman J, Clark-Lewis I, Eaves A, Eaves C Blood, 2002;99(3):792-9. Species: Human Sample Type: Whole Cells Application: Ctrl Tumor necrosis factor-dependent segmental control of MIG expression by high endothelial venules in inflamed lymph nodes regulates monocyte recruitment. Authors: Janatpour MJ, Hudak S, Sathe M, McEvoy LM J. Exp. Med., 2001;194(9):1375-84. Species: Mouse Sample Type: In Vivo Application: Ctrl LeIF: a recombinant Leishmania protein that induces an IL-12-mediated Th1 cytokine profile. Authors: Skeiky YA, Kennedy M, Kaufman D J. Immunol., 1998;161(11):6171-9. Species: Mouse Sample Type: Whole Cells Application: Ctrl Fucose-based PAMPs prime dendritic cells for follicular T helper cell polarization via DC-SIGN-dependent IL-27 production. Authors: Gringhuis S, Kaptein T, Wevers B, van der Vlist M, Klaver E, van Die I, Vriend L, de Jong M, Geijtenbeek T Nat Commun, 0;5(0):5074. Species: Human Sample Type: Whole Cells Application: Isotype control Expand to show all Citations

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Isotype Controls

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Normal Goat IgG Biotinylated Control

Ctrl BAF108 19

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Goat IgG PE-conjugated Antibody

Ctrl IC108P 8

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Goat IgG APC-conjugated Antibody

Ctrl IC108A 2

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Normal Goat IgG Fluorescein-conjugated Control

Ctrl IC108F 1

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Normal Goat IgG Alexa Fluor® 488-conjugated Control

Ctrl IC108G

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Goat IgG Alexa Fluor® 647-conjugated Antibody

Ctrl IC108R

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Normal Goat IgG
PerCP-conjugated Control

Ctrl IC108C

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Normal Goat IgG Alexa Fluor® 700-conjugated Control

Ctrl IC108N

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Average Rating: 4.4 (Based on 11 reviews)

Have you used Normal Goat IgG Control?

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Read what people are saying who have used Normal Goat IgG Control.

We have 8 reviews tested in 6 species: input species here,Goat, Goat, Human, Mouse, Rabbit, Rat.
We have 8 reviews tested in 5 applications: Block/Neutralize, SiteClick, Functional Assay, Immunohistochemistry, Flow Cytometry.

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Block/Neutralize Normal Goat IgG Control AB-108-C Array AB-108-C

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Excellent

B/N

Mouse

Anonymous

04/18/2018

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Block/Neutralize: Normal Goat IgG Control [AB-108-C].

Summary

Application	Block/Neutralize
Sample Tested	lung endothelial cells
Species	Mouse

Other Experimental Details

Normal goat IgG control was used as an isotype control @ 2.5 ug/ml in a FITC-mediated permeability assay in transwells.

Very Good

SiteClick

Goat

Anonymous

10/03/2017

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Summary

Application	SiteClick
Sample Tested	Immature dendritic cells
Species	Goat

Very Good

B/N

Human

Anonymous

05/10/2017

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Summary

Application	Block/Neutralize
Sample Tested	E6.5 mouse embryo fixed in 4% PFA
Species	Human

Normal Goat IgG Control AB-108-C Array AB-108-C

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Excellent

Anonymous

12/19/2016

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: Normal Goat IgG Control [AB-108-C].

Other Experimental Details

Neuronal cultures were incubated with fresh media (control) or with NA 10µM. Three hours later, the media were replaced with half the volume of fresh ones and incubated for five hours. The resultant neuronal conditioned media (CM) were transferred to microglia cultures alone or in combination with a neutralizing antibody (Ab) against CX3CL1 (10µg/ml) or with normal goat IgG. Five hours after the addition of CM, 1µl of LPS (final concentration 0.1 µg/ml) or water was added to all culture wells and incubated for 24h. The concentration of nitrites in the culture media was measured in microglial media. Results published in:Article title: Noradrenaline induces CX3CL1 production and release by neuronsArticle reference: NP6524Journal title: NeuropharmacologyFinal version published online: 08-Dec-2016DOI information: 10.1016/j.neuropharm.2016.12.001

Excellent

Anonymous

12/19/2016

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Other Experimental Details

Used for both FACS and IF. Worked well for both.

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Very Good

Anonymous

11/08/2016

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: Normal Goat IgG Control [AB-108-C].

Very Good

Functional Assay

Mouse

Anonymous

09/01/2016

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Summary

Application	Functional Assay
Sample Tested	Whole blood
Species	Mouse

Very Good

IHC

Rabbit

Anonymous

06/28/2016

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Summary

Application	Immunohistochemistry
Sample Tested	mouse mmp14 +/-
Species	Rabbit

Excellent

Flow

Mouse

Anonymous

06/28/2016

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Summary

Application	Flow Cytometry
Sample Tested	PRIMARY MOUSE CELLS
Species	Mouse

Flow Cytometry Normal Goat IgG Control AB-108-C Array AB-108-C

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Very Good

Flow

Rat

Anonymous

06/01/2016

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Flow Cytometry: Normal Goat IgG Control [AB-108-C].

Summary

Application	Flow Cytometry
Sample Tested	RPE-J
Species	Rat

Very Good

Flow

input species here,Goat

Anonymous

02/22/2016

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Summary

Application	Flow Cytometry
Sample Tested	7TD1 mouse hybridoma cell line
Species	input species here,Goat

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Normal Goat IgG Control

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Normal Goat IgG Biotinylated Control

Goat IgG PE-conjugated Antibody

Goat IgG APC-conjugated Antibody

Normal Goat IgG Fluorescein-conjugated Control

Normal Goat IgG Alexa Fluor® 488-conjugated Control

Goat IgG Alexa Fluor® 647-conjugated Antibody

Normal Goat IgG
PerCP-conjugated Control

Normal Goat IgG Alexa Fluor® 700-conjugated Control

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Normal Goat IgG Control

Certificate of Analysis Lookup

Certificate of Analysis Lookup

Certificate of Analysis Request Form

FAQs

Normal Goat IgG Biotinylated Control

Goat IgG PE-conjugated Antibody

Goat IgG APC-conjugated Antibody

Normal Goat IgG Fluorescein-conjugated Control

Normal Goat IgG Alexa Fluor® 488-conjugated Control

Goat IgG Alexa Fluor® 647-conjugated Antibody

Normal Goat IgG PerCP-conjugated Control

Normal Goat IgG Alexa Fluor® 700-conjugated Control

Summary

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Normal Goat IgG
PerCP-conjugated Control