Normal Rabbit IgG Control

Catalog # Availability Size / Price Qty
AB-105-C
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Detection of Rabbit IgG Isotype Control by Flow Cytometry
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Product Details
Citations (158)
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Reviews (10)

Normal Rabbit IgG Control Summary

Specificity
Serum was obtained from naive (non-immunized) rabbits and purified for use as normal rabbit IgG.
Source
Polyclonal Rabbit IgG
Purification
Protein A or G purified
Immunogen
NA
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Control
Negative control for use in conjunction with R&D Systems antibodies. Use at the same concentration as the detection antibody.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Detection of Rabbit IgG Control by Flow Cytometry HepG2 human hepatocellular carcinoma cell line was stained with Rabbit Anti-Human Klotho beta Monoclonal Antibody (Catalog # MAB58891, filled histogram) or Rabbit IgG Isotype Control Antibody (Catalog # AB-105-C, open histogram), followed by Allophycocyanin-conjugated Anti-Rabbit IgG Secondary Antibody (Catalog # F0111). View our protocol for Staining Membrane-associated Proteins.

Western Blot Detection of Human IgG by Western Blot View Larger

Detection of Human IgG by Western Blot pSTAT5, but not NS1, interacts with the MCM complex.(A) Immunoprecipitation (IP) assay. Cell lysates of NS1Flag-expressing UT7/Epo-S1 cells were prepared for pull-down assays with either anti-Flag-conjugated beads or control beads. Immunoprecipitated proteins were examined for the presence of MCM2 by Western blotting. Blots were reprobed with rabbit anti-pSTAT5(Y694), anti-E2F5, and anti-Flag antibodies. Detection of E2F5 was used as a positive control for NS1 IP. (B) Co-IP assay. UT7/Epo-S1 cells were collected, washed, and lysed with RIPA buffer. After centrifugation, the supernatant was incubated with either rabbit anti-pSTAT5(Y694) or control IgG antibody. Immunoprecipitated proteins were blotted for the presence of the MCM complex with an anti-MCM5 antibody and for pSTAT5 with rabbit anti-pSTAT5(Y694). (C) Reverse Co-IP assay. Reverse Co-IP was performed with an anti-MCM5 antibody. Immunoprecipitated proteins were examined for pSTAT5, MCM2, and MCM5, respectively. (D) Co-IP of lysates treated with DNase. UT7/Epo-S1 cell lysates, either treated or untreated with DNase (750 units of Benzonase) were incubated with anti-pSTAT5(Y694) or control IgG antibodies for Co-IP assay, and immunoprecipitated proteins were examined for MCM2 by Western blot analysis. (E-H) Immunofluorescence analysis. (E&F) Mock- or B19V-infected CD36+ EPCs were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies, followed by (E) incubation with respective secondary antibodies, or by (F) proximal ligation assay, which produces amplified signal for labeled molecules in close proximity. (G) CD36+ EPCs were incubated with either DMSO or pimozide (at 30 μM) for 2 days. And then the cells were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies for proximity ligation assay. (H) Infected EPCs were stained with an anti-capsid antibody. Confocal images were taken with an Eclipse C1 Plus (Nikon) microscope at 100 × magnification. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.ppat.1006370), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Human IgG by Western Blot View Larger

Detection of Human IgG by Western Blot pSTAT5, but not NS1, interacts with the MCM complex.(A) Immunoprecipitation (IP) assay. Cell lysates of NS1Flag-expressing UT7/Epo-S1 cells were prepared for pull-down assays with either anti-Flag-conjugated beads or control beads. Immunoprecipitated proteins were examined for the presence of MCM2 by Western blotting. Blots were reprobed with rabbit anti-pSTAT5(Y694), anti-E2F5, and anti-Flag antibodies. Detection of E2F5 was used as a positive control for NS1 IP. (B) Co-IP assay. UT7/Epo-S1 cells were collected, washed, and lysed with RIPA buffer. After centrifugation, the supernatant was incubated with either rabbit anti-pSTAT5(Y694) or control IgG antibody. Immunoprecipitated proteins were blotted for the presence of the MCM complex with an anti-MCM5 antibody and for pSTAT5 with rabbit anti-pSTAT5(Y694). (C) Reverse Co-IP assay. Reverse Co-IP was performed with an anti-MCM5 antibody. Immunoprecipitated proteins were examined for pSTAT5, MCM2, and MCM5, respectively. (D) Co-IP of lysates treated with DNase. UT7/Epo-S1 cell lysates, either treated or untreated with DNase (750 units of Benzonase) were incubated with anti-pSTAT5(Y694) or control IgG antibodies for Co-IP assay, and immunoprecipitated proteins were examined for MCM2 by Western blot analysis. (E-H) Immunofluorescence analysis. (E&F) Mock- or B19V-infected CD36+ EPCs were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies, followed by (E) incubation with respective secondary antibodies, or by (F) proximal ligation assay, which produces amplified signal for labeled molecules in close proximity. (G) CD36+ EPCs were incubated with either DMSO or pimozide (at 30 μM) for 2 days. And then the cells were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies for proximity ligation assay. (H) Infected EPCs were stained with an anti-capsid antibody. Confocal images were taken with an Eclipse C1 Plus (Nikon) microscope at 100 × magnification. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.ppat.1006370), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Human IgG by Western Blot View Larger

Detection of Human IgG by Western Blot pSTAT5, but not NS1, interacts with the MCM complex.(A) Immunoprecipitation (IP) assay. Cell lysates of NS1Flag-expressing UT7/Epo-S1 cells were prepared for pull-down assays with either anti-Flag-conjugated beads or control beads. Immunoprecipitated proteins were examined for the presence of MCM2 by Western blotting. Blots were reprobed with rabbit anti-pSTAT5(Y694), anti-E2F5, and anti-Flag antibodies. Detection of E2F5 was used as a positive control for NS1 IP. (B) Co-IP assay. UT7/Epo-S1 cells were collected, washed, and lysed with RIPA buffer. After centrifugation, the supernatant was incubated with either rabbit anti-pSTAT5(Y694) or control IgG antibody. Immunoprecipitated proteins were blotted for the presence of the MCM complex with an anti-MCM5 antibody and for pSTAT5 with rabbit anti-pSTAT5(Y694). (C) Reverse Co-IP assay. Reverse Co-IP was performed with an anti-MCM5 antibody. Immunoprecipitated proteins were examined for pSTAT5, MCM2, and MCM5, respectively. (D) Co-IP of lysates treated with DNase. UT7/Epo-S1 cell lysates, either treated or untreated with DNase (750 units of Benzonase) were incubated with anti-pSTAT5(Y694) or control IgG antibodies for Co-IP assay, and immunoprecipitated proteins were examined for MCM2 by Western blot analysis. (E-H) Immunofluorescence analysis. (E&F) Mock- or B19V-infected CD36+ EPCs were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies, followed by (E) incubation with respective secondary antibodies, or by (F) proximal ligation assay, which produces amplified signal for labeled molecules in close proximity. (G) CD36+ EPCs were incubated with either DMSO or pimozide (at 30 μM) for 2 days. And then the cells were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies for proximity ligation assay. (H) Infected EPCs were stained with an anti-capsid antibody. Confocal images were taken with an Eclipse C1 Plus (Nikon) microscope at 100 × magnification. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.ppat.1006370), licensed under a CC-BY license. Not internally tested by R&D Systems.

Western Blot Detection of Normal Rabbit IgG Control by Western Blot View Larger

Detection of Normal Rabbit IgG Control by Western Blot pSTAT5, but not NS1, interacts with the MCM complex.(A) Immunoprecipitation (IP) assay. Cell lysates of NS1Flag-expressing UT7/Epo-S1 cells were prepared for pull-down assays with either anti-Flag-conjugated beads or control beads. Immunoprecipitated proteins were examined for the presence of MCM2 by Western blotting. Blots were reprobed with rabbit anti-pSTAT5(Y694), anti-E2F5, and anti-Flag antibodies. Detection of E2F5 was used as a positive control for NS1 IP. (B) Co-IP assay. UT7/Epo-S1 cells were collected, washed, and lysed with RIPA buffer. After centrifugation, the supernatant was incubated with either rabbit anti-pSTAT5(Y694) or control IgG antibody. Immunoprecipitated proteins were blotted for the presence of the MCM complex with an anti-MCM5 antibody and for pSTAT5 with rabbit anti-pSTAT5(Y694). (C) Reverse Co-IP assay. Reverse Co-IP was performed with an anti-MCM5 antibody. Immunoprecipitated proteins were examined for pSTAT5, MCM2, and MCM5, respectively. (D) Co-IP of lysates treated with DNase. UT7/Epo-S1 cell lysates, either treated or untreated with DNase (750 units of Benzonase) were incubated with anti-pSTAT5(Y694) or control IgG antibodies for Co-IP assay, and immunoprecipitated proteins were examined for MCM2 by Western blot analysis. (E-H) Immunofluorescence analysis. (E&F) Mock- or B19V-infected CD36+ EPCs were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies, followed by (E) incubation with respective secondary antibodies, or by (F) proximal ligation assay, which produces amplified signal for labeled molecules in close proximity. (G) CD36+ EPCs were incubated with either DMSO or pimozide (at 30 μM) for 2 days. And then the cells were co-stained with rabbit anti-STAT5 and mouse anti-MCM2 antibodies for proximity ligation assay. (H) Infected EPCs were stained with an anti-capsid antibody. Confocal images were taken with an Eclipse C1 Plus (Nikon) microscope at 100 × magnification. Image collected and cropped by CiteAb from the following open publication (https://dx.plos.org/10.1371/journal.ppat.1006370), licensed under a CC-BY license. Not internally tested by R&D Systems.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Dissolve the lyophilized rabbit IgG in sterile PBS, pH 7.4. If 1 mL of PBS is used, the antibody concentration will be 1 mg/mL.
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Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: IgG

R&D Systems offers a range of secondary antibodies and controls for flow cytometry, immunohistochemistry, and Western blotting. We provide species-specific secondary antibodies that are available with a variety of conjugated labels.

Our NorthernLights fluorescent secondary antibodies are bright and resistant to photobleaching. We are currently offering secondary antibodies recognizing mouse, rat, goat, sheep, and rabbit IgG as well as chicken IgY. These reagents are available with three distinct excitation and emission maxima, making them ideal for multi-color fluorescence microscopy.

Long Name
Immunoglobulin G
Alternate Names
IgG; Immunoglobulin G; ImmunoglobulinG

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Citations for Normal Rabbit IgG Control

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

158 Citations: Showing 1 - 10
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  1. CASC4/GOLM2 drives high grade serous carcinoma anoikis resistance through the recycling of EGFR
    Authors: Bapat, J;Yamamoto, TM;Woodruff, ER;Qamar, L;Mikeska, RG;Aird, KM;Watson, ZL;Brubaker, LW;Bitler, BG;
    Cancer gene therapy
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  2. Spinal cord injury dysregulates fibro-adipogenic progenitors miRNAs signaling to promote neurogenic heterotopic ossifications
    Authors: Jules Gueguen, Dorothée Girard, Bastien Rival, Juliette Fernandez, Marie-Emmanuelle Goriot, Sébastien Banzet
    Commun Biol
  3. SARS-CoV-2 ORF8 accessory protein is a virulence factor
    Authors: Bello-Perez, M;Hurtado-Tamayo, J;Mykytyn, AZ;Lamers, MM;Requena-Platek, R;Schipper, D;Muñoz-Santos, D;Ripoll-Gómez, J;Esteban, A;Sánchez-Cordón, PJ;Enjuanes, L;Haagmans, BL;Sola, I;
    mBio
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  4. Characterization of a spontaneous mouse model of mild, accelerated aging via ECM degradation in emphysematous lungs
    Authors: Tanino, R;Tsubata, Y;Hotta, T;Okimoto, T;Amano, Y;Takechi, M;Tanaka, T;Akita, T;Nagase, M;Yamashita, C;Wada, K;Isobe, T;
    Scientific reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells
    Authors: Lisa Bauer, Laurine C Rijsbergen, Lonneke Leijten, Feline FW Benavides, Danny Noack, Mart M Lamers et al.
    Life Science Alliance
  6. Spinal Cathepsin S promotes visceral hypersensitivity via FKN/CX3CR1/p38 MAPK signaling pathways
    Authors: Sun, P;Lin, W;Weng, Y;Gong, J;Huang, Y;Tang, Y;Lin, C;Chen, A;Chen, Y;
    Molecular pain
    Species: Rat
    Sample Types:
    Applications: In Vivo
  7. Osteoclast-derived IGF1 induces RANKL production in osteocytes and contributes to Pagetic lesion formation
    Authors: Miyagawa, K;Tenshin, H;Mulcrone, PL;Delgado-Calle, J;Subler, MA;Windle, JJ;Chirgwin, JM;Roodman, GD;Kurihara, N;
    JCI insight
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  8. O-GlcNAcylation of RIPK1 rescues red blood cells from necroptosis
    Authors: Junghwa Seo, Yeolhoe Kim, Suena Ji, Han Byeol Kim, Hyeryeon Jung, Eugene C. Yi et al.
    Frontiers in Immunology
  9. Elevated plasma complement factor H related 5 protein is associated with venous thromboembolism
    Authors: Iglesias, MJ;Sanchez-Rivera, L;Ibrahim-Kosta, M;Naudin, C;Munsch, G;Goumidi, L;Farm, M;Smith, PM;Thibord, F;Kral-Pointner, JB;Hong, MG;Suchon, P;Germain, M;Schottmaier, W;Dusart, P;Boland, A;Kotol, D;Edfors, F;Koprulu, M;Pietzner, M;Langenberg, C;Damrauer, SM;Johnson, AD;Klarin, DM;Smith, NL;Smadja, DM;Holmström, M;Magnusson, M;Silveira, A;Uhlén, M;Renné, T;Martinez-Perez, A;Emmerich, J;Deleuze, JF;Antovic, J;Soria Fernandez, JM;Assinger, A;Schwenk, JM;Souto Andres, JC;Morange, PE;Butler, LM;Trégouët, DA;Odeberg, J;
    Nature communications
    Species: Human
    Sample Types: Plasma
    Applications: Mass Spectrometry
  10. Neutralization of excessive levels of active TGF-beta 1 reduces MSC recruitment and differentiation to mitigate peritendinous adhesion
    Authors: YuSheng Li, Xiao Wang, Bo Hu, Qi Sun, Mei Wan, Andrew Carr et al.
    Bone Research
  11. BAFF and APRIL counterregulate susceptibility to inflammation-induced preterm birth
    Authors: JR Doll, ME Moreno-Fer, TE Stankiewic, JL Wayland, A Wilburn, B Weinhaus, CA Chougnet, D Giordano, M Cappellett, P Presicce, SG Kallapur, N Salomonis, T Tilburgs, S Divanovic
    Cell Reports, 2023-04-05;42(4):112352.
    Species: Rabbit
    Sample Types: Whole Tissue
    Applications: IHC
  12. Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer's Disease
    Authors: Chun-Sun Jiang, Tapasi Rana, Lee-Way Jin, Susan A Farr, John E Morley, Hongwei Qin et al.
    Aging Dis
  13. Spontaneous Osteoclastogenesis, a risk factor for bone metastasis in advanced luminal A-type breast cancer patients
    Authors: Valeria Fernández Vallone, Francisco Raúl Borzone, Leandro Marcelo Martinez, María Belén Giorello, Hosoon Choi, Federico Dimase et al.
    Frontiers in Oncology
  14. Anti-DNA-IgM Favors the Detection of NET-Associated Extracellular DNA
    Authors: H Wang, AM Stehr, J Singh, L Zlatar, A Hartmann, K Evert, E Naschberge, S von Stillf, P Boor, LE Muñoz, J Knopf, M Stürzl, M Herrmann
    International Journal of Molecular Sciences, 2023-02-17;24(4):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  15. Identification of AXL as a co-receptor for human parvovirus B19 infection of human erythroid progenitors
    Authors: K Ning, W Zou, P Xu, F Cheng, EY Zhang, A Zhang-Chen, S Kleiboeker, J Qiu
    Science Advances, 2023-01-11;9(2):eade0869.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization Control
  16. Identification and functional characterization of potential oncofetal targets in human hepatocellular carcinoma
    Authors: Mei-Mei Li, Fan-En Kong, Guang-Meng Li, Yi-Ti He, Xiao-Feng Zhang, Cheng-Yang Zhang et al.
    STAR Protocols
  17. Neural crest cell-placodal neuron interactions are mediated by Cadherin-7 and N-cadherin during early chick trigeminal ganglion assembly
    Authors: Caroline A. Halmi, Chyong-Yi Wu, Lisa A. Taneyhill
    F1000Research
  18. Adenosine A2a Receptor Antagonism Restores Additive Cytotoxicity by Cytotoxic T Cells in Metabolically Perturbed Tumors
    Authors: Jeroen Slaats, Esther Wagena, Daan Smits, Annemarie A. Berends, Ella Peters, Gert-Jan Bakker et al.
    Cancer Immunology Research
  19. The envelope protein of Zika virus interacts with apolipoprotein E early in the infectious cycle and this interaction is conserved on the secreted viral particles
    Authors: Yannick Tréguier, Jade Cochard, Julien Burlaud-Gaillard, Roxane Lemoine, Philippe Chouteau, Philippe Roingeard et al.
    Virology Journal
  20. L‐type Voltage‐Gated calcium channels partly mediate Mechanotransduction in the intervertebral disc
    Authors: Philip Poillot, Joseph W. Snuggs, Christine L. Le Maitre, Jacques M. Huyghe
    JOR SPINE
  21. Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair
    Authors: EC Jeffery, TLA Mann, JA Pool, Z Zhao, SJ Morrison
    Cell Stem Cell, 2022-10-21;29(11):1547-1561.e6.
    Species: Mouse
    Sample Types: Whole Cells
  22. Type I Interferon Receptor Subunit 1 Deletion Attenuates Experimental Abdominal Aortic Aneurysm Formation
    Authors: T Shoji, J Guo, Y Ge, Y Li, G Li, T Ikezoe, W Wang, X Zheng, S Zhao, N Fujimura, J Huang, B Xu, RL Dalman
    Biomolecules, 2022-10-21;12(10):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  23. Distinct role of mitochondrial function and protein kinase C in intimal and medial calcification in vitro
    Authors: Marina A. Heuschkel, Anne Babler, Jonas Heyn, Emiel P. C. van der Vorst, Marja Steenman, Maren Gesper et al.
    Frontiers in Cardiovascular Medicine
  24. In vitro and in vivo differences in neurovirulence between D614G, Delta And Omicron BA.1 SARS-CoV-2 variants
    Authors: L Bauer, M Rissmann, FFW Benavides, L Leijten, P van Run, L Begeman, EJB Veldhuis K, B Lendemeije, H Smeenk, FMS de Vrij, SA Kushner, MPG Koopmans, B Rockx, D van Riel
    Acta neuropathologica communications, 2022-09-05;10(1):124.
    Species: Hamster
    Sample Types: Whole Tissue
    Applications: IHC Control
  25. Sox9 directs divergent epigenomic states in brain tumor subtypes
    Authors: D Sardar, HC Chen, A Reyes, S Varadharaj, A Jain, C Mohila, R Curry, B Lozzi, K Rajendran, A Cervantes, K Yu, A Jalali, G Rao, SC Mack, B Deneen
    Oncogene, 2022-07-15;119(29):e2202015119.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ChIP Control
  26. p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation
    Authors: JP Pinnamanen, VP Singh, MB Kim, CT Ryan, A Pugazenthi, D Sanagasett, M Mathison, J Yang, TK Rosengart
    Scientific Reports, 2022-07-06;12(1):11416.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ChIP Control
  27. Stromal changes in the aged lung induce an emergence from melanoma dormancy
    Authors: ME Fane, Y Chhabra, GM Alicea, DA Maranto, SM Douglass, MR Webster, VW Rebecca, GE Marino, F Almeida, BL Ecker, DJ Zabransky, L Hüser, T Beer, HY Tang, A Kossenkov, M Herlyn, DW Speicher, W Xu, X Xu, EM Jaffee, JA Aguirre-Gh, AT Weeraratna
    Nature, 2022-06-01;606(7913):396-405.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Isotype Control
  28. Cross-talk between mutant p53 and p62/SQSTM1 augments cancer cell migration by promoting the degradation of cell adhesion proteins
    Authors: S Mukherjee, M Maddalena, Y Lü, S Martinez, NB Nataraj, A Noronha, S Sinha, K Teng, V Cohen-Kapl, T Ziv, S Arandkar, O Hassin, R Chatterjee, AC Pirona, M Shreberk-S, A Gershoni, Y Aylon, Z Elazar, Y Yarden, D Schramek, M Oren
    Proceedings of the National Academy of Sciences of the United States of America, 2022-04-19;119(17):e2119644119.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  29. DNA sequence-dependent formation of heterochromatin nanodomains
    Authors: GJ Thorn, CT Clarkson, A Rademacher, H Mamayusupo, G Schotta, K Rippe, VB Teif
    Nature Communications, 2022-04-06;13(1):1861.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP
  30. Inhibition of Integrin alpha v beta 6 Activation of TGF‐ beta Attenuates Tendinopathy
    Authors: Xiao Wang, Shen Liu, Tao Yu, Senbo An, Ruoxian Deng, Xiaohua Tan et al.
    Advanced Science
  31. Transcription Regulation of Tceal7 by the Triple Complex of Mef2c, Creb1 and Myod
    Authors: Z Xiong, M Wang, S You, X Chen, J Lin, J Wu, X Shi
    Biology, 2022-03-16;11(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ChIP
  32. ULK3-dependent activation of GLI1 promotes DNMT3A expression upon autophagy induction
    Authors: P González-R, M Cheray, L Keane, P Engskog-Vl, B Joseph
    Autophagy, 2022-02-28;0(0):1-12.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP Control
  33. Macrophage IL-1beta promotes arteriogenesis by autocrine STAT3- and NF-kappaB-mediated transcription of pro-angiogenic VEGF-A
    Authors: CS Mantsounga, C Lee, J Neverson, S Sharma, A Healy, JM Berus, C Parry, NM Ceneri, F López-Girá, HJ Chun, Q Lu, F Sellke, G Choudhary, AR Morrison
    Cell Reports, 2022-02-01;38(5):110309.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Isotype Control
  34. C2cd6-encoded CatSper tau targets sperm calcium channel to Ca2+ signaling domains in the flagellar membrane
    Authors: Jae Yeon Hwang, Huafeng Wang, Yonggang Lu, Masahito Ikawa, Jean-Ju Chung
    Cell Reports
  35. Interplay in neural functions of cell adhesion molecule close homolog of L1 (CHL1) and Programmed Cell Death 6 (PDCD6)
    Authors: Gabriele Loers, Thomas Theis, Helen Baixia Hao, Ralf Kleene, Sanjana Arsha, Nina Samuel et al.
    FASEB BioAdvances
  36. Hippo Pathway Effector Tead1 Induces Cardiac Fibroblast to Cardiomyocyte Reprogramming
    Authors: Vivek P. Singh, Jaya P. Pinnamaneni, Aarthi Pugazenthi, Deepthi Sanagasetti, Megumi Mathison, James F. Martin et al.
    Journal of the American Heart Association
  37. Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells
    Authors: Nam-Kyung Yu, Daniel B. McClatchy, Jolene K. Diedrich, Sarah Romero, Jun-Hyeok Choi, Salvador Martínez-Bartolomé et al.
    iScience
  38. Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes
    Authors: M Minguzzi, V Panichi, S D'Adamo, S Cetrullo, L Cattini, F Flamigni, E Mariani, RM Borzì
    International Journal of Molecular Sciences, 2021-11-05;22(21):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  39. TGF beta 1 signaling protects chondrocytes against oxidative stress via FOXO1–autophagy axis
    Authors: Ichiro Kurakazu, Yukio Akasaki, Hidetoshi Tsushima, Takuya Sueishi, Masakazu Toya, Masanari Kuwahara et al.
    Osteoarthritis and Cartilage
  40. Matricellular Protein SPARCL1 Regulates Blood Vessel Integrity and Antagonizes Inflammatory Bowel Disease
    Authors: Daniela Regensburger, Clara Tenkerian, Victoria Pürzer, Benjamin Schmid, Thomas Wohlfahrt, Iris Stolzer et al.
    Inflammatory Bowel Diseases
  41. Phase separation of Epstein-Barr virus EBNA2 protein reorganizes chromatin topology for epigenetic regulation
    Authors: Yiting Yang, Xidong Ye, Ranran Dai, Zhaoqiang Li, Yan Zhang, Wei Xue et al.
    Communications Biology
  42. N6-methyladenosine promotes induction of ADAR1-mediated A-to-I RNA editing to suppress aberrant antiviral innate immune responses
    Authors: H Terajima, M Lu, L Zhang, Q Cui, Y Shi, J Li, C He
    PloS Biology, 2021-07-29;19(7):e3001292.
    Species: Human
    Sample Types: Cell Lysate
    Applications: RNA Immunoprecipitation Contro
  43. Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
    Authors: F Pecori, N Kondo, C Ogura, T Miura, M Kume, Y Minamijima, K Yamamoto, S Nishihara
    Cell Reports, 2021-07-13;36(2):109361.
    Species: Human, Mouse
    Sample Types: Cell Lysates
    Applications: IP Control
  44. Extracellular vesicles carry SARS‐CoV‐2 spike protein and serve as decoys for neutralizing antibodies
    Authors: Zach Troyer, Najwa Alhusaini, Caroline O. Tabler, Thomas Sweet, Karina Inacio Ladislau de Carvalho, Daniela M. Schlatzer et al.
    Journal of Extracellular Vesicles
  45. 4-Hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen
    Authors: Hannah Tabakh, Adelle P McFarland, Maureen K Thomason, Alex J Pollock, Rochelle C Glover, Shivam A Zaver et al.
    eLife
  46. Steroid hormones and human choriogonadotropin influence the distribution of alpha6-integrin and desmoplakin 1 in gland-like endometrial epithelial spheroids
    Authors: V. U. Buck, M. T. Kohlen, A. K. Sternberg, B. Rösing, J. Neulen, R. E. Leube et al.
    Histochemistry and Cell Biology
  47. Chondrogenesis mediates progression of ankylosing spondylitis through heterotopic ossification
    Authors: Tao Yu, Jianguo Zhang, Wei Zhu, Xiao Wang, Yun Bai, Bin Feng et al.
    Bone Research
  48. Regulation of dual leucine zipper kinase activity through its interaction with calcineurin
    Authors: JD Escobar, A Kutschenko, S Schröder, R Blume, KA Köster, C Painer, T Lemcke, W Maison, E Oetjen
    Cellular Signalling, 2021-02-16;82(0):109953.
    Species: Hamster
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation Control
  49. Two distinct trophectoderm lineage stem cells from human pluripotent stem cells
    Authors: A Mischler, V Karakis, J Mahinthaku, CK Carberry, A San Miguel, JE Rager, RC Fry, BM Rao
    The Journal of Biological Chemistry, 2021-02-05;0(0):100386.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  50. CD48 Expression on Eosinophils in Nasal Polyps of Chronic Rhinosinusitis Patients
    Authors: Yara Zoabi, Fidan Rahimli Alekberli, Yael Minai-Fleminger, Ron Eliashar, Francesca Levi-Schaffer
    International Archives of Allergy and Immunology
  51. Novel bi-allelic variants in DNAH2 cause severe asthenoteratozoospermia with multiple morphological abnormalities of the flagella
    Authors: Y Gao, S Tian, Y Sha, X Zha, H Cheng, A Wang, C Liu, M Lv, X Ni, Q Li, H Wu, Q Tan, D Tang, B Song, D Ding, J Cong, Y Xu, P Zhou, Z Wei, Y Cao, Y Xu, F Zhang, X He
    Reproductive biomedicine online, 2021-01-22;0(0):.
    Species: Human
    Sample Types: Spermatozoa
    Applications: ICC
  52. Mutation of SPINOPHILIN (PPP1R9B) found in human tumors promotes the tumorigenic and stemness properties of cells
    Authors: EM Verdugo-Si, AM Rojas, S Muñoz-Galv, D Otero-Albi, A Carnero
    Theranostics, 2021-01-19;11(7):3452-3471.
    Species: Human
    Sample Types: Protein
    Applications: Immunoprecipitation
  53. Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis
    Authors: Sameh S. M. Soliman, Clara Baldin, Yiyou Gu, Shakti Singh, Teclegiorgis Gebremariam, Marc Swidergall et al.
    Nature Microbiology
  54. Genome-wide investigation of the dynamic changes of epigenome modifications after global DNA methylation editing
    Authors: J Broche, G Kungulovsk, P Bashtrykov, P Rathert, A Jeltsch
    Nucleic Acids Research, 2021-01-11;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: ChIP
  55. Molecular Targeting of H/MDM-2 Oncoprotein in Human Colon Cancer Cells and Stem-like Colonic Epithelial-derived Progenitor Cells
    Authors: ANUSHA THADI, WILLIAM F. MORANO, MARIAN KHALILI, BLAKE D. BABCOCK, MOHAMMAD F. SHAIKH, DESHKA S. FOSTER et al.
    Anticancer Research
  56. Platelets Selectively Regulate the Release of BDNF, But Not That of Its Precursor Protein, proBDNF
    Authors: Jessica Le Blanc, Samuel Fleury, Imane Boukhatem, Jean-Christophe Bélanger, Mélanie Welman, Marie Lordkipanidzé
    Frontiers in Immunology
  57. Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis
    Authors: F Pecori, Y Akimoto, H Hanamatsu, JI Furukawa, Y Shinohara, Y Ikehara, S Nishihara
    J. Cell. Sci., 2020-10-23;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  58. Identification of drivers of breast cancer invasion by secretome analysis: insight into CTGF signaling
    Authors: JW Hellinger, F Schömel, JV Buse, C Lenz, G Bauerschmi, G Emons, C Gründker
    Sci Rep, 2020-10-21;10(1):17889.
    Species: Human
    Sample Types: Reference Standard
    Applications: Control
  59. Identification of epilepsy-associated neuronal subtypes and gene expression underlying epileptogenesis
    Authors: U Pfisterer, V Petukhov, S Demharter, J Meichsner, JJ Thompson, MY Batiuk, AA Martinez, NA Vasistha, A Thakur, J Mikkelsen, I Adorjan, LH Pinborg, TH Pers, J von Engelh, PV Kharchenko, K Khodosevic
    Nat Commun, 2020-10-07;11(1):5038.
    Species: Human
    Sample Types: Tissue Homogenates
    Applications: IHC
  60. Overexpression of microRNA-367 inhibits angiogenesis in ovarian cancer by downregulating the expression of LPA1
    Authors: Q Zheng, X Dai, W Fang, Y Zheng, J Zhang, Y Liu, D Gu
    Cancer Cell Int, 2020-10-02;20(0):476.
    Species: Human, Mouse
    Sample Types: Cell Lysates, Whole Tissue
    Applications: IHC, Western Blot
  61. Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation
    Authors: Ewa Jankowska−Gan, Vrushali V. Agashe, Diego A. Lema, Ying Zhou, Laura Gonzalez Bosc, Jeremy A. Sullivan et al.
    Transplantation Direct
  62. A role of the CTCF binding site at enhancer Ealpha in the dynamic chromatin organization of the Tcra-Tcrd locus
    Authors: H Zhao, Z Li, Y Zhu, S Bian, Y Zhang, L Qin, AK Naik, J He, Z Zhang, MS Krangel, B Hao
    Nucleic Acids Res., 2020-09-25;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP Control, Immunoprecipitation
  63. Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture
    Authors: Tomáš Vaisar, Jie H. Hu, Nathan Airhart, Kate Fox, Jay Heinecke, Roberto F. Nicosia et al.
    Circulation Research
  64. The DNA methyltransferase DNMT3A contributes to autophagy long-term memory
    Authors: P González-R, M Cheray, J Füllgrabe, M Salli, P Engskog-Vl, L Keane, V Cunha, A Lupa, W Li, Q Ma, K Dreij, MG Rosenfeld, B Joseph
    Autophagy, 2020-09-14;0(0):1-19.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  65. Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
    Authors: N Niyonzima, SS Bakke, I Gregersen, S Holm, Ø Sandanger, HL Orrem, B Sporsheim, L Ryan, XY Kong, TB Dahl, M Skjelland, KK Sørensen, AM Rokstad, A Yndestad, E Latz, L Gullestad, GØ Andersen, JK Damås, P Aukrust, TE Mollnes, B Halvorsen, T Espevik
    EBioMedicine, 2020-09-11;60(0):102985.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  66. Leptospiral LPS escapes mouse TLR4 internalization and TRIF?associated antimicrobial responses through O antigen and associated lipoproteins
    Authors: D Bonhomme, I Santecchia, F Vernel-Pau, M Caroff, P Germon, G Murray, B Adler, IG Boneca, C Werts
    PLoS Pathog., 2020-08-13;16(8):e1008639.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  67. Lipid-specific IgMs induce antiviral responses in the CNS: implications for progressive multifocal leukoencephalopathy in multiple sclerosis
    Authors: L Hayden, T Semenoff, V Schultz, SF Merz, KJ Chapple, M Rodriguez, AE Warrington, X Shi, CS McKimmie, JM Edgar, K Thümmler, C Linington, M Pingen
    Acta Neuropathol Commun, 2020-08-13;8(1):135.
    Species: Mouse, Rat
    Sample Types: Whole Cells
    Applications: Isotype Control, Neutralization Control
  68. Abnormal Microvascular Architecture, Fibrosis, and Pericyte Characteristics in the Calf Muscle of Peripheral Artery Disease Patients with Claudication and Critical Limb Ischemia
    Authors: CJ Mietus, TJ Lackner, PS Karvelis, GT Willcockso, CM Shields, NG Lambert, P Koutakis, MA Fuglestad, H Hernandez, GR Haynatzki, JKS Kim, HK DeSpiegela, II Pipinos, GP Casale
    J Clin Med, 2020-08-08;9(8):.
    Species: Bovine, Human
    Sample Types: Whole Cells, Whole Tissue
    Applications: ICC, Isotype Control
  69. Neonatal exposure to chlordecone alters female social behaviors and central estrogen alpha receptor expression in socially monogamous mandarin voles
    Authors: Ting Lian, Xudong Zhang, Xiye Wang, Rong Wang, Huan Gao, Fadao Tai et al.
    Toxicology Research
  70. Regulation of Spermine Oxidase through Hypoxia-Inducible Factor-1alpha Signaling in Retinal Glial Cells under Hypoxic Conditions
    Authors: D Wu, K Noda, M Murata, Y Liu, A Kanda, S Ishida
    Invest. Ophthalmol. Vis. Sci., 2020-06-03;61(6):52.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Isotype Control
  71. Entry and exit of chemotherapeutically-promoted cellular dormancy in glioblastoma cells is differentially affected by the chemokines CXCL12, CXCL16, and CX3CL1
    Authors: Vivian Adamski, Kirsten Hattermann, Carolin Kubelt, Gesa Cohrs, Ralph Lucius, Michael Synowitz et al.
    Oncogene
  72. Na+/Ca2 + Exchange and Pacemaker Activity of Interstitial Cells of Cajal
    Authors: Haifeng Zheng, Bernard T. Drumm, Mei Hong Zhu, Yeming Xie, Kate E. O’Driscoll, Salah A. Baker et al.
    Frontiers in Physiology
  73. Complement inhibitor factor H expressed by breast cancer cells differentiates CD14+ human monocytes into immunosuppressive macrophages
    Authors: Karolina I. Smolag, Christine M. Mueni, Karin Leandersson, Karin Jirström, Catharina Hagerling, Matthias Mörgelin et al.
    OncoImmunology
  74. Ophiopogonin D promotes bone regeneration by stimulating CD31hi EMCNhi vessel formation
    Authors: Mi Yang, Chang‐Jun Li, Ye Xiao, Qi Guo, Yan Huang, Tian Su et al.
    Cell Proliferation
  75. Roxatidine inhibits fibrosis by inhibiting NF?kappaB and MAPK signaling in macrophages sensing breast implant surface materials
    Authors: L Ji, T Wang, L Tian, H Song, M Gao
    Mol Med Rep, 2019-11-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  76. Unsaturated Aldehyde Acrolein Promotes Retinal Glial Cell Migration
    Authors: M Murata, K Noda, S Yoshida, M Saito, A Fujiya, A Kanda, S Ishida
    Invest. Ophthalmol. Vis. Sci., 2019-10-01;60(13):4425-4435.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  77. In Vivo Imaging of Small Molecular Weight Peptides for Targeted Renal Drug Delivery: A Study in Normal and Polycystic Kidney Diseased Mice
    Authors: Stephen C. Lenhard, Allen McAlexander, Anthony Virtue, William Fieles, Tina Skedzielewski, Mary Rambo et al.
    Journal of Pharmacology and Experimental Therapeutics
  78. Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes
    Authors: Abani Kanta Naik, Aaron T. Byrd, Aaron C.K. Lucander, Michael S. Krangel
    Journal of Experimental Medicine
  79. Analysis of regulator of G-protein signalling 2 (RGS2) expression and function during prostate cancer progression
    Authors: A Linder, M Hagberg Th, JE Damber, K Welén
    Sci Rep, 2018-11-22;8(1):17259.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  80. A Lamina-Associated Domain Border Governs Nuclear Lamina Interactions, Transcription, and Recombination of the Tcrb Locus
    Authors: S Chen, TR Luperchio, X Wong, EB Doan, AT Byrd, K Roy Choudh, KL Reddy, MS Krangel
    Cell Rep, 2018-11-13;25(7):1729-1740.e6.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP Control
  81. Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice
    Authors: Ping Yang, Shan Lv, Yan Wang, Yi Peng, Zixing Ye, Zhuying Xia et al.
    Bone
  82. A Kaposi's Sarcoma-Associated Herpesvirus Infection Mechanism Is Independent of Integrins alpha 3 beta 1, alpha V beta 3, and alpha V beta 5
    Authors: Allison Alwan TerBush, Florianne Hafkamp, Hee Jun Lee, Laurent Coscoy
    Journal of Virology
  83. Ciliary parathyroid hormone signaling activates transforming growth factor-beta to maintain intervertebral disc homeostasis during aging
    Authors: Liwei Zheng, Yong Cao, Shuangfei Ni, Huabin Qi, Zemin Ling, Xin Xu et al.
    Bone Research
  84. Cathelicidin-Derived Antimicrobial Peptides Inhibit Zika Virus Through Direct Inactivation and Interferon Pathway
    Authors: Miao He, Hainan Zhang, Yuju Li, Guangshun Wang, Beisha Tang, Jeffrey Zhao et al.
    Frontiers in Immunology
  85. Genome-Wide Bimolecular Fluorescence Complementation-Based Proteomic Analysis ofToxoplasma gondiiROP18's Human Interactome Shows Its Key Role in Regulation of Cell Immunity and Apoptosis
    Authors: J Xia, L Kong, LJ Zhou, SZ Wu, LJ Yao, C He, CY He, HJ Peng
    Front Immunol, 2018-02-05;9(0):61.
    Species: Primate - Chlorocebus aethiops (African Green Monkey)
    Sample Types: Cell Lysates
    Applications: Western Blot
  86. Oncogenic dependency on beta -catenin in liver cancer cell lines correlates with pathway activation
    Authors: Zhihu Ding, Chaomei Shi, Lan Jiang, Tatiana Tolstykh, Hui Cao, Dinesh S. Bangari et al.
    Oncotarget
  87. MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2
    Authors: GA Howe, K Kazda, CL Addison
    PLoS ONE, 2017-10-04;12(10):e0185619.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  88. Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
    Authors: SS Bakke, MH Aune, N Niyonzima, K Pilely, L Ryan, M Skjelland, P Garred, P Aukrust, B Halvorsen, E Latz, JK Damås, TE Mollnes, T Espevik
    J. Immunol., 2017-08-30;0(0):.
    Species: Human
    Sample Types: Plasma
    Applications: Flow Cytometry
  89. Interactions between fibroblastic reticular cells and B cells promote mesenteric lymph node lymphangiogenesis
    Authors: L Kumar Dube, P Karempudi, SA Luther, B Ludewig, NL Harris
    Nat Commun, 2017-08-28;8(1):367.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  90. MiR-497?195 cluster regulates angiogenesis during coupling with osteogenesis by maintaining endothelial Notch and HIF-1? activity
    Authors: M Yang, CJ Li, X Sun, Q Guo, Y Xiao, T Su, ML Tu, H Peng, Q Lu, Q Liu, HB He, TJ Jiang, MX Lei, M Wan, X Cao, XH Luo
    Nat Commun, 2017-07-07;8(0):16003.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  91. Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex
    Authors: SS Ganaie, W Zou, P Xu, X Deng, S Kleiboeker, J Qiu
    PLoS Pathog., 2017-05-01;13(5):e1006370.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  92. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages
    Authors: L Zhu, A Gomez-Dura, G Saretzki, S Jin, K Tilgner, D Melguizo-S, G Anyfantis, J Al-Aama, L Vallier, P Chinnery, M Lako, L Armstrong
    J. Cell Biol., 2016-10-17;215(2):187-202.
    Species: Human
    Sample Types: Protein
    Applications: ChIP
  93. Dux4 controls migration of mesenchymal stem cells through the Cxcr4-Sdf1 axis
    Authors: P Dmitriev, E Kiseleva, O Kharchenko, E Ivashkin, A Pichugin, P Dessen, T Robert, F Coppée, A Belayew, G Carnac, D Laoudj-Che, M Lipinski, A Vasiliev, YS Vassetzky
    Oncotarget, 2016-10-04;7(40):65090-65108.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  94. Activity-Regulated Cytoskeleton-Associated Protein Controls AMPAR Endocytosis through a Direct Interaction with Clathrin-Adaptor Protein 2123
    Authors: Luis L. P. DaSilva, Mark J. Wall, Luciana P. de Almeida, Sandrine C. Wauters, Yunan C. Januário, Jürgen Müller et al.
    eNeuro
  95. TGF-? Neutralization Enhances AngII-Induced Aortic Rupture and Aneurysm in Both Thoracic and Abdominal Regions
    Authors: X Chen, DL Rateri, DA Howatt, A Balakrishn, JJ Moorleghen, LA Cassis, A Daugherty
    PLoS ONE, 2016-04-22;11(4):e0153811.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  96. Tumor-infiltrating monocytes/macrophages promote tumor invasion and migration by upregulating S100A8 and S100A9 expression in cancer cells
    Authors: SY Lim, AE Yuzhalin, AN Gordon-Wee, RJ Muschel
    Oncogene, 2016-04-18;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  97. Interleukin-10 deficiency impairs regulatory T cell-derived neuropilin-1 functions and promotes Th1 and Th17 immunity
    Authors: Shimin Wang, Xiang Gao, Guobo Shen, Wei Wang, Jingyu Li, Jingyi Zhao et al.
    Scientific Reports
  98. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells
    Authors: A Spiegel, MW Brooks, S Houshyar, F Reinhardt, M Ardolino, E Fessler, MB Chen, JA Krall, J DeCock, IK Zervantona, A Iannello, Y Iwamoto, V Cortez-Ret, RD Kamm, MJ Pittet, DH Raulet, RA Weinberg
    Cancer Discov, 2016-04-12;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  99. Lipoprotein receptor-related protein 6 is required for parathyroid hormone-induced Sost suppression
    Authors: Changjun Li, Weishan Wang, Liang Xie, Xianghang Luo, Xu Cao, Mei Wan
    Annals of the New York Academy of Sciences
  100. TGRL Lipolysis Products Induce Stress Protein ATF3 via the TGF-beta Receptor Pathway in Human Aortic Endothelial Cells
    Authors: Larissa Eiselein, Tun Nyunt, Michael W. Lamé, Kit F. Ng, Dennis W. Wilson, John C. Rutledge et al.
    PLOS ONE
  101. EpCAM-Independent Enrichment of Circulating Tumor Cells in Metastatic Breast Cancer
    Authors: Helen Schneck, Berthold Gierke, Frauke Uppenkamp, Bianca Behrens, Dieter Niederacher, Nikolas H. Stoecklein et al.
    PLOS ONE
  102. Convergence of cMyc and beta-catenin on Tcf7l1 enables endoderm specification.
    Authors: Morrison G, Scognamiglio R, Trumpp A, Smith A
    EMBO J, 2015-12-16;35(3):356-68.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP
  103. miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program
    Authors: Shicheng Su, Qiyi Zhao, Chonghua He, Di Huang, Jiang Liu, Fei Chen et al.
    Nature Communications
  104. Characterization of In Vitro Engineered Human Adipose Tissues: Relevant Adipokine Secretion and Impact of TNF-alpha.
    Authors: Aubin K, Safoine M, Proulx M, Audet-Casgrain M, Côté J, Tetu F, Roy A, Fradette J
    PLoS ONE, 2015-09-14;10(9):e0137612.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC Control
  105. Suppression of Hyperactive Immune Responses Protects against Nitrogen Mustard Injury.
    Authors: Au L, Meisch J, Das L, Binko A, Boxer R, Wen A, Steinmetz N, Lu K
    J Invest Dermatol, 2015-08-19;135(12):2971-81.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  106. A discrete chromatin loop in the mouse Tcra-Tcrd locus shapes the TCRdelta and TCRalpha repertoires.
    Authors: Chen L, Carico Z, Shih H, Krangel M
    Nat Immunol, 2015-08-10;16(10):1085-93.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP
  107. Optimisations and Challenges Involved in the Creation of Various Bioluminescent and Fluorescent Influenza A Virus Strains for In Vitro and In Vivo Applications.
    Authors: Spronken M, Short K, Herfst S, Bestebroer T, Vaes V, van der Hoeven B, Koster A, Kremers G, Scott D, Gultyaev A, Sorell E, de Graaf M, Barcena M, Rimmelzwaan G, Fouchier R
    PLoS ONE, 2015-08-04;10(8):e0133888.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC Control
  108. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
    Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
    J Neuroinflammation, 2015-06-16;12(0):119.
    Species: Human
    Sample Types: Whole Cells
    Applications: IHC
  109. Stearoyl-CoA desaturase 1 and paracrine diffusible signals have a major role in the promotion of breast cancer cell migration induced by cancer-associated fibroblasts.
    Authors: Angelucci C, Maulucci G, Colabianchi A, Iacopino F, D'Alessio A, Maiorana A, Palmieri V, Papi M, De Spirito M, Di Leone A, Masetti R, Sica G
    Br J Cancer, 2015-04-16;112(10):1675-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization Control
  110. An anti-silencer- and SATB1-dependent chromatin hub regulates Rag1 and Rag2 gene expression during thymocyte development.
    Authors: Hao B, Naik A, Watanabe A, Tanaka H, Chen L, Richards H, Kondo M, Taniuchi I, Kohwi Y, Kohwi-Shigematsu T, Krangel M
    J Exp Med, 2015-04-06;212(5):809-24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Immunoprecipitation
  111. Discovery of molecular markers to discriminate corneal endothelial cells in the human body.
    Authors: Yoshihara M, Ohmiya H, Hara S, Kawasaki S, Hayashizaki Y, Itoh M, Kawaji H, Tsujikawa M, Nishida K
    PLoS ONE, 2015-03-25;10(3):e0117581.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  112. T-cell receptor alpha enhancer is inactivated in alphabeta T lymphocytes.
    Authors: del Blanco B, Angulo U, Krangel M, Hernandez-Munain C
    Proc Natl Acad Sci U S A, 2015-03-23;112(14):E1744-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Immunoprecipitation
  113. HEB associates with PRC2 and SMAD2/3 to regulate developmental fates.
    Authors: Yoon, Se-Jin, Foley, Joseph W, Baker, Julie C
    Nat Commun, 2015-03-16;6(0):6546.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Co-Immunoprecipitation
  114. Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence.
    Authors: Gonzalez-Valdes I, Hidalgo I, Bujarrabal A, Lara-Pezzi E, Padron-Barthe L, Garcia-Pavia P, Gomez-del Arco P, Redondo J, Ruiz-Cabello J, Jimenez-Borreguero L, Enriquez J, de la Pompa J, Hidalgo A, Gonzalez S
    Nat Commun, 2015-03-09;6(0):6473.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  115. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
    Authors: Li, Chang-Ju, Cheng, Peng, Liang, Meng-Ke, Chen, Yu-Si, Lu, Qiong, Wang, Jin-Yu, Xia, Zhu-Ying, Zhou, Hou-De, Cao, Xu, Xie, Hui, Liao, Er-Yuan, Luo, Xiang-Ha
    J Clin Invest, 2015-03-09;125(4):1509-22.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  116. A transient wave of BMP signaling in the retina is necessary for Muller glial differentiation.
    Authors: Ueki Y, Wilken M, Cox K, Chipman L, Bermingham-McDonogh O, Reh T
    Development, 2015-02-01;142(3):533-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ChIP
  117. Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment.
    Authors: Tomellini E, Touil Y, Lagadec C, Julien S, Ostyn P, Ziental-Gelus N, Meignan S, Lengrand J, Adriaenssens E, Polakowska R, Le Bourhis X
    Stem Cells, 2015-02-01;33(2):342-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC Control
  118. Regulation of caspase-3 processing by cIAP2 controls the switch between pro-inflammatory activation and cell death in microglia
    Authors: E Kavanagh, J Rodhe, M A Burguillos, J L Venero, B Joseph
    Cell Death & Disease
  119. Specification of Vdelta and Valpha usage by Tcra/Tcrd locus V gene segment promoters.
    Authors: Naik A, Hawwari A, Krangel M
    J Immunol, 2014-12-03;194(2):790-4.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ChIP Control
  120. The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions
    Authors: Esther Steiner, Gaby U. Enzmann, Ruth Lyck, Shuo Lin, Markus A. Rüegg, Stephan Kröger et al.
    Cell and Tissue Research
  121. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture.
    Authors: Astarita, Jillian, Cremasco, Viviana, Fu, Jianxin, Darnell, Max C, Peck, James R, Nieves-Bonilla, Janice M, Song, Kai, Kondo, Yuji, Woodruff, Matthew, Gogineni, Alvin, Onder, Lucas, Ludewig, Burkhard, Weimer, Robby M, Carroll, Michael, Mooney, David J, Xia, Lijun, Turley, Shannon
    Nat Immunol, 2014-10-27;16(1):75-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  122. CD4(+)Foxp3(+) Tregs protect against innate immune cell-mediated fulminant hepatitis in mice.
    Authors: Hou X, Song J, Su J, Huang D, Gao W, Yan J, Shen J
    Mol Immunol, 2014-10-12;63(2):420-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization Control
  123. S100A4 is upregulated in proliferative diabetic retinopathy and correlates with markers of angiogenesis and fibrogenesis
    Authors: Ahmed M. Abu El-Asrar, Mohd Imtiaz Nawaz, Gert De Hertogh, Kaiser Alam, Mohammad Mairaj Siddiquei, Kathleen Van den Eynde et al.
    Mol. Vis
  124. Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
    Authors: Serkan Kir, James P. White, Sandra Kleiner, Lawrence Kazak, Paul Cohen, Vickie E. Baracos et al.
    Nature
  125. Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
    Authors: De Simone V, Franze E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, Sica G, Sileri P, MacDonald T, Pallone F, Monteleone G, Stolfi C
    Oncogene, 2014-09-01;34(27):3493-503.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  126. Proteomic analysis of the action of the Mycobacterium ulcerans toxin mycolactone: targeting host cells cytoskeleton and collagen.
    Authors: Gama J, Ohlmeier S, Martins T, Fraga A, Sampaio-Marques B, Carvalho M, Proenca F, Silva M, Pedrosa J, Ludovico P
    PLoS Negl Trop Dis, 2014-08-07;8(8):e3066.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Neutralization
  127. Differential Requirement for P2X7R Function in IL-17 Dependent vs. IL-17 Independent Cellular Immune Responses
    Authors: J.A. Sullivan, E. Jankowska-Gan, L. Shi, D. Roenneburg, S. Hegde, D.S. Greenspan et al.
    American Journal of Transplantation
  128. Fibrodysplasia ossificans progressiva-related activated activin-like kinase signaling enhances osteoclast formation during heterotopic ossification in muscle tissues.
    Authors: Yano M, Kawao N, Okumoto K, Tamura Y, Okada K, Kaji H
    J Biol Chem, 2014-05-05;289(24):16966-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Isotype Control
  129. In vivo neuronal action potential recordings via three-dimensional microscale needle-electrode arrays.
    Authors: Fujishiro A, Kaneko H, Kawashima T, Ishida M, Kawano T
    Sci Rep, 2014-05-02;4(0):4868.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  130. NADPH oxidase-independent formation of extracellular DNA traps by basophils.
    Authors: Morshed M, Hlushchuk R, Simon D, Walls A, Obata-Ninomiya K, Karasuyama H, Djonov V, Eggel A, Kaufmann T, Simon H, Yousefi S
    J Immunol, 2014-04-25;192(11):5314-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Isotype Control
  131. Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release.
    Authors: Samstad E, Niyonzima N, Nymo S, Aune M, Ryan L, Bakke S, Lappegard K, Brekke O, Lambris J, Damas J, Latz E, Mollnes T, Espevik T
    J Immunol, 2014-02-19;192(6):2837-45.
    Species: Human
    Sample Types:
    Applications: Isotype Control
  132. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
    Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
    Mucosal Immunol, 2014-01-15;7(5):1079-93.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  133. Autophagy fosters myofibroblast differentiation through MTORC2 activation and downstream upregulation of CTGF.
    Authors: Bernard M, Dieude M, Yang B, Hamelin K, Underwood K, Hebert M
    Autophagy, 2014-01-01;10(12):2193-207.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization
  134. A soluble fucose-specific lectin from Aspergillus fumigatus conidia--structure, specificity and possible role in fungal pathogenicity.
    Authors: Houser J, Komarek J, Kostlanova N, Cioci G, Varrot A, Kerr S, Lahmann M, Balloy V, Fahy J, Chignard M, Imberty A, Wimmerova M
    PLoS ONE, 2013-12-10;8(12):e83077.
    Species: Fungus - Aspergillus fumigatus
    Sample Types: Whole Tissue
    Applications: IHC
  135. FGF10 Signaling differences between type I pleuropulmonary blastoma and congenital cystic adenomatoid malformation
    Authors: Guillaume Lezmi, Virginie Verkarre, Naziha Khen-Dunlop, Shamila Vibhushan, Alice Hadchouel, Caroline Rambaud et al.
    Orphanet Journal of Rare Diseases
  136. Characterization of dextran sodium sulfate-induced inflammation and colonic tumorigenesis in Smad3(-/-) mice with dysregulated TGF beta
    Authors: Audrey Seamons, Piper M. Treuting, Thea Brabb, Lillian Maggio-Price
    PLoS ONE
  137. WISP1/CCN4: A Potential Target for Inhibiting Prostate Cancer Growth and Spread to Bone
    Authors: Mitsuaki Ono, Colette A. Inkson, Robert Sonn, Tina M. Kilts, Luis F. de Castro, Azusa Maeda et al.
    PLoS ONE
  138. Developmentally programmed 3' CpG island methylation confers tissue- and cell-type-specific transcriptional activation.
    Authors: Yu, Da-Hai, Ware, Carol, Waterland, Robert A, Zhang, Jiexin, Chen, Miao-Hsu, Gadkari, Manasi, Kunde-Ramamoorthy, Govindar, Nosavanh, Lagina M, Shen, Lanlan
    Mol Cell Biol, 2013-03-04;33(9):1845-58.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Immunoprecipitation
  139. Tcra gene recombination is supported by a Tcra enhancer- and CTCF-dependent chromatin hub
    Authors: Han-Yu Shih, Jiyoti Verma-Gaur, Ali Torkamani, Ann J. Feeney, Niels Galjart, Michael S. Krangel
    Proceedings of the National Academy of Sciences
  140. The miR-17/92 cluster is targeted by STAT5 but dispensable for mammary development
    Authors: Yonatan Feuermann, Gertraud W. Robinson, Bing-Mei Zhu, Keunsoo Kang, Noa Raviv, Daisuke Yamaji et al.
    genesis
  141. CX3CL1 expression in the conjunctiva is involved in immune cell trafficking during toxic ocular surface inflammation.
    Authors: Denoyer A, Godefroy D, Celerier I, Frugier J, Riancho L, Baudouin F, Rostene W, Baudouin C
    Mucosal Immunol, 2012-06-13;5(0):702.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  142. Genome-wide analyses reveal the extent of opportunistic STAT5 binding that does not yield transcriptional activation of neighboring genes
    Authors: Bing-Mei Zhu, Keunsoo Kang, Ji Hoon Yu, Weiping Chen, Harold E. Smith, Daeyoup Lee et al.
    Nucleic Acids Research
  143. Regulation of T cell receptor beta allelic exclusion by gene segment proximity and accessibility1,2
    Authors: Hrisavgi D. Kondilis-Mangum, Han-Yu Shih, Grace Mahowald, Barry P. Sleckman, Michael S. Krangel
    The Journal of Immunology
  144. Transforming Growth Factor Beta Expression by Human Vascular Cells Inhibits Interferon Gamma Production and Arterial Media Injury by Alloreactive Memory T Cells
    Authors: Amir H. Lebastchi, Salman F. Khan, Lingfeng Qin, Wei Li, Jing Zhou, Narutoshi Hibino et al.
    American Journal of Transplantation
  145. Long-distance regulation of fetal Vδ gene segment TRDV4 by the Tcrd enhancer1,2
    Authors: Bingtao Hao, Michael S. Krangel
    The Journal of Immunology
  146. A barrier-type insulator forms a boundary between active and inactive chromatin at the murine T cell receptor beta locus1,2
    Authors: Juan Carabana, Akiko Watanabe, Bingtao Hao, Michael S. Krangel
    The Journal of Immunology
  147. MEK5 is Activated by Shear Stress, Activates ERK5 and Induces KLF4 to Modulate TNF Responses in Human Dermal Microvascular Endothelial Cells
    Authors: PAUL R. CLARK, TODD J. JENSEN, MARTIN S. KLUGER, MAURICE MORELOCK, ADEDAYO HANIDU, ZHENHAO QI et al.
    Microcirculation
  148. Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells.
    Authors: Yamakawa N, Uchida T, Matthay MA, Makita K
    Am. J. Physiol. Lung Cell Mol. Physiol., 2011-01-21;300(4):L516-25.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Control
  149. A requirement for Lim domain binding protein 1 in erythropoiesis
    Authors: LiQi Li, Jan Y. Lee, Jennifer Gross, Sang-Hyun Song, Ann Dean, Paul E. Love
    Journal of Experimental Medicine
  150. Stemness markers characterize IGR-CaP1, a new cell line derived from primary epithelial prostate cancer.
    Authors: Chauchereau A, Al Nakouzi N, Gaudin C, Le Moulec S, Compagno D, Auger N, Benard J, Opolon P, Rozet F, Validire P, Fromont G, Fizazi K
    Exp. Cell Res., 2010-10-23;317(3):262-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Flow Cytometry Control
  151. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
    Authors: Suzuki K, Maruya M, Kawamoto S
    Immunity, 2010-07-23;33(1):71-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Control
  152. Stromal regulation of vessel stability by MMP14 and TGFbeta
    Authors: Nor E. Sounni, Kerstin Dehne, Leon van Kempen, Mikala Egeblad, Nesrine I. Affara, Ileana Cuevas et al.
    Disease Models & Mechanisms
  153. Tumor necrosis factor alpha as a new target for renal cell carcinoma: two sequential phase II trials of infliximab at standard and high dose.
    Authors: Harrison ML, Obermueller E, Maisey NR, Hoare S, Edmonds K, Li NF, Chao D, Hall K, Lee C, Timotheadou E, Charles K, Ahern R, King DM, Eisen T, Corringham R, DeWitte M, Balkwill F, Gore M
    J. Clin. Oncol., 2007-10-10;25(29):4542-9.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Control
  154. Endothelial damage from cytomegalovirus-specific host immune response can be prevented by targeted disruption of fractalkine-CX3CR1 interaction.
    Authors: Bolovan-Fritts CA, Spector SA
    Blood, 2007-09-25;111(1):175-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  155. Increase in transforming growth factor-beta in the brain during infection is related to fever, not depression of spontaneous motor activity.
    Authors: Matsumura S, Shibakusa T, Fujikawa T, Yamada H, Inoue K, Fushiki T
    Neuroscience, 2006-12-06;144(3):1133-40.
    Species: Rat
    Sample Types: CSF
    Applications: Control
  156. Natural and induced CD4+CD25+ cells educate CD4+CD25- cells to develop suppressive activity: the role of IL-2, TGF-beta, and IL-10.
    Authors: Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA
    J. Immunol., 2004-05-01;172(9):5213-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Control
  157. Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
    Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
    J. Immunol., 2004-05-01;172(9):5753-64.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Control
  158. Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2.
    Authors: Viti J, Gulacsi A, Lillien L
    J. Neurosci., 2003-07-02;23(13):5919-27.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Control

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Normal Rabbit IgG Control
By Anonymous on 09/22/2019
Application: WB Sample Tested: Recombinant protein Species: Human

Normal Rabbit IgG Control
By Lucy Quach on 11/05/2018
Application: Flow Sample Tested: SK-BR-3 human breast cancer cell line Species: Human

Normal Rabbit IgG Control
By Anonymous on 04/20/2018
Application: Flow Sample Tested: Human Cancer cell line Species: Human

Normal Rabbit IgG Control
By Anonymous on 08/24/2017
Application: Flow Sample Tested: Adult splenocytes Species: Mouse

Isotype control


Normal Rabbit IgG Control
By Anonymous on 06/17/2017
Application: B/N Sample Tested: Peritoneal macrophages Species: Human

Normal Rabbit IgG Control
By Anonymous on 05/22/2017
Application: Immunocytochemistry/Immunofluorescence Sample Tested: Neutrophils Species: Human

Very disappointed, the antibody is too noisy for IF with human neutrophils to be used as a control, compared to another IgG control that we have.ER

Technical Service is following up


Normal Rabbit IgG Control
By Anonymous on 10/11/2016
Application: Immunocytochemistry/Immunofluorescence Sample Tested: mouse P14 Species: Mouse and Rabbit

used as negative control


Normal Rabbit IgG Control
By Anonymous on 07/27/2016
Application: Func Sample Tested: mouse lung Species: Mouse

Normal Rabbit IgG Control
By Anonymous on 06/28/2016
Application: Flow Sample Tested: primary mouse cells Species: Mouse

Normal Rabbit IgG Control
By jingbin wang on 02/22/2016
Application: Flow Sample Tested: Mouse lymphocytes Species: input species here