N^ω-Propyl-L-arginine hydrochloride

Key Product Details

Product Description

N^ω-Propyl-L-arginine hydrochloride is a highly selective and potent inhibitor of nNOS (K_i = 57 nM). Displays 3158-fold and 149-fold selectivity over iNOS and eNOS respectively. Hypotensive in vivo.

Product Specifications for N^ω-Propyl-L-arginine hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for N^ω-Propyl-L-arginine hydrochloride

The following data is based on the product molecular weight 252.74.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

7 6 5 4 3 2 1 Recalculate

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.96 mL	19.78 mL	39.57 mL
5 mM	0.79 mL	3.96 mL	7.91 mL
10 mM	0.40 mL	1.98 mL	3.96 mL
50 mM	0.08 mL	0.40 mL	0.79 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 670 publications citing the usage of this product.

• Zhang Potent and selective inhibition of neuronal nitric oxide synthase by N^ω-propyl-L-arginine. J.Med.Chem. 1997 PMID: 9397167
• Kakoki The influence of nitric oxide synthase 1 on blood flow and interstitial nitric oxide in the kidney. Am.J.Physiol.Regul.Integr.Comp.Physiol. 2001 PMID: 11404282

Product Documents for N^ω-Propyl-L-arginine hydrochloride