Catalog Number: 4212
Chemical Name: 6,6'-Dithiodi-2-naphthtol
Biological Activity
Negative control of IPA 3, a direct, non-competitive inhibitor of group I p21-activated kinase (Pak1).

Active Analog also available.

Technical Data
  • M.Wt:
    350.45
  • Formula:
    C20H14O2S2
  • Solubility:
    Soluble to 75 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    6088-51-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Other Product-Specific Information:
Background References
  1. An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase.
    Deacon et al.
    Chem.Biol., 2008;15:322
Citations:

The citations listed below are publications that use Tocris products. Selected citations for PIR 3.5 include:

2 Citations: Showing 1 - 2
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  1. Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.
    Authors: Imle Et al.
    MBio 2015;6
  2. Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.
    Authors: Molosh Et al.
    J Biol Chem 2014;17:1583
Tocris Small Molecules
Description Application Cat# Citations Images  

IPA 3

3622 15  
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