IFN-gamma (Interferon-gamma) is the prototype proinflammatory cytokine and is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells. It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, upregulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects. In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation. IFN-gamma dimers signal through a receptor complex of two IFN-gamma R1 and two IFN-gamma R2 subunits.
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Quantikine Immunoassay Control Group 281
R&D Systems | Catalog # QC281
For use with catalog number DIF50C
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Key Product Details
Applications
Control
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Formulation, Preparation, and Storage
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IFN-gamma
Long Name
Interferon gamma
Alternate Names
IFG, IFI, IFNG, IFNgamma
Entrez Gene IDs
Gene Symbol
IFNG
Additional IFN-gamma Products
Product Documents for Quantikine Immunoassay Control Group 281
Certificate of Analysis
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Note: Certificate of Analysis not available for kit components.
Product Specific Notices for Quantikine Immunoassay Control Group 281
For research use only
Related Research Areas
Customer Reviews for Quantikine Immunoassay Control Group 281 (3)
5 out of 5
3 Customer Ratings
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Verified Customer | Posted 11/13/2020QC worked great. The location of the QC281 on the plate is as follows: Well A3 : R&D Low Well G12: R&D Medium Well H12: R&D High
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Verified Customer | Posted 11/12/2020QC was in wells G12 & H12 in singleton- signal was clear and within the expected values for our range.
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Verified Customer | Posted 11/12/2020Values for QC were great, they were well within the given ranges. A3 is low, 12G is medium and 12H is the high QC on this plate.
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Associated Pathways
Hematopoietic Stem Cell Differentiation Pathways & Lineage-specific Markers
IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
Innate Lymphoid Cell Differentiation Pathways
