Recombinant Human FGF basic (146 aa) Protein

Formulations:
Catalog # Availability Size / Price Qty
233-FB-025
233-FB-01M
233-FB-500
233-FB-010
Recombinant Human FGF basic (146 aa) Protein Bioactivity
2 Images
Product Details
Citations (255)
FAQs
Supplemental Products
Reviews (12)

Recombinant Human FGF basic (146 aa) Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using NR6R‑3T3 mouse fibroblast cells. Raines, E.W. et al. (1985) Methods Enzymol. 109:749. The ED50 for this effect is 0.1-0.6 ng/mL.
The specific activity of Recombinant Human FGF basic is approximately 800 IU/μg, which is calibrated against recombinant human FGF basic WHO International Standard (NIBSC code: 90/712).
Source
E. coli-derived human FGF basic protein
Pro143-Ser288, with an N-terminal Ala
Accession #
N-terminal Sequence
Analysis
Ala-Pro143
Predicted Molecular Mass
16.5 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

233-FB

Formulation Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl with BSA as a carrier protein.
Reconstitution Reconstitute at 100-250 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

233-FB/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Tris-HCl and NaCl.
Reconstitution Reconstitute at 100-250 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Human FGF basic (146 aa) Protein Bioactivity View Larger

Recombinant Human FGF basic (146aa) (Catalog # 233-FB) stimulates cell proliferation of the NR6R‑3T3 mouse fibroblast cell line. The ED50 for this effect is 0.1-0.6 ng/mL.

SDS-PAGE Recombinant Human FGF basic (146 aa) Protein SDS-PAGE View Larger

1 µg/lane of Recombinant Human FGF basic (146 aa) was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: FGF basic

FGF basic is a member of the FGF family of at least 23 related mitogenic proteins which show 35-60% amino acid conservation. FGF acidic and basic, unlike the other members of the family, lack signal peptides and are apparently secreted by mechanisms other than the classical protein secretion pathway. FGF basic has been isolated from a number of sources, including neural tissue, pituitary, adrenal cortex, corpus luteum, and placenta. This factor contains four cysteine residues, but reduced FGF basic retains full biological activity, indicating that disulfide bonds are not required for this activity. A variety of forms of FGF basic are produced as a result of N-terminal extensions. These extensions affect localization of FGF basic in cellular compartments but do not affect biological activity. Binding of FGF to heparin or cell surface heparan sulfate proteoglycans is necessary for binding of FGF to high affinity FGF receptors. FGF acidic and basic appear to bind to the same high affinity receptors and show a similar range of biological activities. FGF basic stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. FGF basic induces neuron differentiation, survival, and regeneration. FGF basic also modulates embryonic development and differentiation. These observed in vitro functions of FGF basic suggest FGF basic may play a role in vivo in the modulation of such normal processes as angiogenesis, wound healing and tissue repair, embryonic development and differentiation, and neuronal function and neural degeneration. Additionally, FGF basic may participate in the production of a variety of pathological conditions resulting from excessive cell proliferation and excessive angiogenesis.

References
  1. Coulier, F. et al. (1997) J. Mol. Evol. 44:43.
  2. Chen, C.H. et al. (2004) Curr. Vasc. Pharmacol. 2:33.
  3. Mohammadi, M. et al. (2005) Curr. Opin. Struct. Biol. 15:506.
  4. Fernig, D. et al. (1994) Prog. Growth Factor Res. 5:353.
Long Name
Fibroblast Growth Factor basic
Entrez Gene IDs
2247 (Human); 14173 (Mouse); 281161 (Bovine); 403857 (Canine); 100033955 (Equine)
Alternate Names
basic fibroblast growth factor bFGF; Basic fibroblast growth factor; bFGF; FGF basic; FGF2; FGF-2; FGF2AS; FGFBprostatropin; fibroblast growth factor 2 (basic); GFG1; HBGF-2; HBGH-2; heparin-binding growth factor 2; NUDT6; Prostatropin

Citations for Recombinant Human FGF basic (146 aa) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

255 Citations: Showing 1 - 10
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  1. Endothelial heparan sulfate 6-o-sulfation levels regulate angiogenic responses of endothelial cells to fibroblast growth factor 2 and vascular endothelial growth factor.
    Authors: Ferreras, Cristina, Rushton, Graham, Cole, Claire L, Babur, Muhammad, Telfer, Brian A, van Kuppevelt, Toin H, Gardiner, John M, Williams, Kaye J, Jayson, Gordon C, Avizienyte, Egle
    J Biol Chem, 2102;287(43):36132-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Skeletal Muscle Stem Cells from PSC-Derived Teratomas Have Functional Regenerative Capacity
    Authors: SS Chan, RW Arpke, A Filareto, N Xie, MP Pappas, JS Penaloza, RCR Perlingeir, M Kyba
    Cell Stem Cell, 2018;23(1):74-85.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Segmental Additive Tissue Engineering
    Authors: M Sladkova, R Alawadhi, R Jaragh Alh, A Esmael, S Alansari, M Saad, J Mulla Yous, L Alqaoud, GM de Peppo
    Sci Rep, 2018;8(1):10895.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Transcriptional activator DOT1L putatively regulates human embryonic stem cell differentiation into the cardiac lineage
    Authors: V Pursani, D Bhartiya, V Tanavde, M Bashir, P Sampath
    Stem Cell Res Ther, 2018;9(1):97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells
    Authors: N Dreyer-And, AS Almeida, P Jensen, M Kamand, J Okarmus, T Rosenberg, SD Friis, A Martínez S, M Blaabjerg, BW Kristensen, T Skrydstrup, JB Gramsberge, HLA Vieira, M Meyer
    PLoS ONE, 2018;13(1):e0191207.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. DNA topoisomerase II? stimulates neurite outgrowth in neural differentiated human mesenchymal stem cells through regulation of Rho-GTPases (RhoA/Rock2 pathway) and Nurr1 expression
    Authors: M Zaim, S Isik
    Stem Cell Res Ther, 2018;9(1):114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Attenuation of reactive gliosis in stroke-injured mouse brain does not affect neurogenesis from grafted human iPSC-derived neural progenitors
    Authors: C Laterza, N Uoshima, D Tornero, U Wilhelmsso, A Stokowska, R Ge, M Pekny, O Lindvall, Z Kokaia
    PLoS ONE, 2018;13(2):e0192118.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance
    Authors: IG Ryoo, BH Choi, SK Ku, MK Kwak
    Redox Biol, 2018;17(0):246-258.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. A novel ex vivo Huntington's disease model for studying GABAergic neurons and cell grafts by laser microdissection
    Authors: EM André, N Daviaud, L Sindji, J Cayon, R Perrot, CN Montero-Me
    PLoS ONE, 2018;13(3):e0193409.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferation
    Authors: JJ Gell, J Zhao, D Chen, TJ Hunt, AT Clark
    Stem Cell Res, 2018;27(0):46-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma
    Authors: F Ihler, R Gratz, HA Wolff, BG Weiss, M Bertlich, J Kitz, G Salinas, M Rave-Fränk, M Canis
    Biomed Res Int, 2018;2018(0):7929104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Highly efficient methods to obtain homogeneous dorsal neural progenitor cells from human and mouse embryonic stem cells and induced pluripotent stem cells
    Authors: M Zhang, J Ngo, F Pirozzi, YP Sun, A Wynshaw-Bo
    Stem Cell Res Ther, 2018;9(1):67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Laterally confined growth of cells induces nuclear reprogramming in the absence of exogenous biochemical factors
    Authors: B Roy, S Venkatacha, P Ratna, Y Wang, DS Jokhun, M Nagarajan, GV Shivashank
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
    Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Significant therapeutic effects of adult human multipotent neural cells on spinal cord injury
    Authors: KH Lee, HJ Pyeon, H Nam, JS Won, JY Hwang, KA Lee, JY Yeon, SC Hong, DH Nam, K Lee, SH Lee, KM Joo
    Stem Cell Res, 2018;31(0):71-78.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Streptozotocin-induced ?-cell damage, high fat diet, and metformin administration regulate Hes3 expression in the adult mouse brain
    Authors: P Nikolakopo, A Chatzigeor, I Kourtzelis, L Toutouna, J Masjkur, C Arps-Forke, SW Poser, J Rozman, B Rathkolb, JA Aguilar-Pi,, E Wolf, M Klingenspo, M Ollert, C Schmidt-We, H Fuchs, V Gailus-Dur, M Hrabe de A, V Tsata, LS Monasor, M Troullinak, A Witt, V Anastasiou, G Chrousos, CX Yi, C García-Các, MH Tschöp, SR Bornstein, A Androutsel
    Sci Rep, 2018;8(1):11335.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. SNAIL is a key regulator of alveolar rhabdomyosarcoma tumor growth and differentiation through repression of MYF5 and MYOD function
    Authors: K Skrzypek, A Kusienicka, E Trzyna, B Szewczyk, A Ulman, P Konieczny, T Adamus, B Badyra, M Kortylewsk, M Majka
    Cell Death Dis, 2018;9(6):643.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Functional 3D Human Liver Bud Assembled from MSC-Derived Multiple Liver Cell Lineages
    Authors: J Li, F Xing, F Chen, L He, KF So, Y Liu, J Xiao
    Cell Transplant, 2018;0(0):9636897187803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. The antigen ASB4 on cancer stem cells serves as a target for CTL immunotherapy of colorectal cancer
    Authors: S Miyamoto, V Kochin, T Kanaseki, A Hongo, S Tokita, Y Kikuchi, A Takaya, Y Hirohashi, T Tsukahara, T Terui, K Ishitani, F Hata, I Takemasa, A Miyazaki, H Hiratsuka, N Sato, T Torigoe
    Cancer Immunol Res, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition
    Authors: W Wang, D Chen, K Zhu
    J. Exp. Clin. Cancer Res., 2018;37(1):37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. In Vitro Regeneration of Patient-specific Ear-shaped Cartilage and Its First Clinical Application for Auricular Reconstruction
    Authors: G Zhou, H Jiang, Z Yin, Y Liu, Q Zhang, C Zhang, B Pan, J Zhou, X Zhou, H Sun, D Li, A He, Z Zhang, W Zhang, W Liu, Y Cao
    EBioMedicine, 2018;28(0):287-302.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Acoustic waves improves retroviral transduction in human retinal stem cells
    Authors: CH Peng, LC Woung, KH Lu, CY Tsai, SD Lee, CS Huang, TC Lin, KH Chien, DK Hwang
    J Chin Med Assoc, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis
    Authors: LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Gol
    J. Clin. Invest., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. ING5 activity in self-renewal of glioblastoma stem cells via calcium and follicle stimulating hormone pathways
    Authors: F Wang, AY Wang, C Chesnelong, Y Yang, A Nabbi, S Thalappill, V Alekseev, K Riabowol
    Oncogene, 2018;37(3):286-301.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. TNF-? induces human neural progenitor cell survival after oxygen-glucose deprivation by activating the NF-?B pathway
    Authors: M Kim, K Jung, IS Kim, IS Lee, Y Ko, JE Shin, KI Park
    Exp. Mol. Med., 2018;50(4):14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Differentiation of human induced pluripotent stem cells into nucleus pulposus-like cells
    Authors: R Tang, L Jing, VP Willard, CL Wu, F Guilak, J Chen, LA Setton
    Stem Cell Res Ther, 2018;9(1):61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Radiation-induced alternative transcripts as detected in total and polysome-bound mRNA
    Authors: A Wahba, MC Ryan, UT Shankavara, K Camphausen, PJ Tofilon
    Oncotarget, 2018;9(1):691-705.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Subcellular localisation modulates ubiquitylation and degradation of Ascl1
    Authors: S Gillotin, JD Davies, A Philpott
    Sci Rep, 2018;8(1):4625.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Neural Stem Cell-Conditioned Medium Ameliorated Cerebral Ischemia-Reperfusion Injury in Rats
    Authors: H Yang, C Wang, H Chen, L Li, S Ma, H Wang, Y Fu, T Qu
    Stem Cells Int, 2018;2018(0):4659159.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Brain and spinal cord injury repair by implantation of human neural progenitor cells seeded onto polymer scaffolds
    Authors: JE Shin, K Jung, M Kim, K Hwang, H Lee, IS Kim, BH Lee, IS Lee, KI Park
    Exp. Mol. Med., 2018;50(4):39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination
    Authors: Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, HE Shick, E Garrison, M T Karl, DC Factor, ZS Nevin, JL Sax, MA Thompson, Y Fedorov, J Jin, WK Wilson, M Giera, F Bracher, RH Miller, PJ Tesar, DJ Adams
    Nature, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Oxidation Prevents HMGB1 Inhibition on PDGF-Induced Differentiation of Multipotent Vascular Stem Cells to Smooth Muscle Cells: A Possible Mechanism Linking Oxidative Stress to Atherosclerosis
    Authors: X Meng, W Su, X Tao, M Sun, R Ying, W Wei, B Wang
    Biomed Res Int, 2018;2018(0):4019814.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Therapeutic Delivery Specifications Identified Through Compartmental Analysis of a Mesenchymal Stromal Cell-Immune Reaction
    Authors: M Li, D Khong, LY Chin, A Singleton, B Parekkadan
    Sci Rep, 2018;8(1):6816.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Breast cancer stem cells in HER2-negative breast cancer cells contribute to HER2-mediated radioresistance and molecular subtype conversion: clinical implications for serum HER2 in recurrent HER2-negative breast cancer
    Authors: YG Kim, YN Yoon, HS Choi, JH Kim, H Seol, JK Lee, MK Seong, IC Park, KI Kim, HA Kim, JS Kim, WC Noh
    Oncotarget, 2018;9(5):5811-5822.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Higher-Order Kidney Organogenesis from Pluripotent Stem Cells
    Authors: A Taguchi, R Nishinakam
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: differentiation
  36. Expression of Pluripotency Markers in Non-pluripotent Human Neural Stem and Progenitor Cells
    Authors: PH Vincent, E Benedikz, P Uhlen, O Hovatta, E Sundström
    Stem Cells Dev., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Ccl5 establishes an autocrine high-grade glioma growth regulatory circuit critical for mesenchymal glioblastoma survival
    Authors: Y Pan, LJ Smithson, Y Ma, D Hambardzum, DH Gutmann
    Oncotarget, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
    Authors: H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng
    Sci Rep, 2017;7(0):43736.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived From Human Induced Pluripotent Stem Cells After Intracerebral Transplantation
    Authors: JC Niclis, C Turner, J Durnall, S McDougal, JA Kauhausen, B Leaw, M Dottori, CL Parish, LH Thompson
    Stem Cells Transl Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Targeting BMI1(+) Cancer Stem Cells Overcomes Chemoresistance and Inhibits Metastases in Squamous Cell Carcinoma
    Authors: D Chen, M Wu, Y Li, I Chang, Q Yuan, M Ekimyan-Sa, P Deng, B Yu, Y Yu, J Dong, JM Szymanski, S Ramadoss, J Li, CY Wang
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells
    Authors: L Wang, Y Hirohashi, T Ogawa, M Shen, R Takeda, A Murai, E Yamamoto, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, T Nishidate, K Okita, G Kutomi, N Sato, I Takemasa, T Torigoe
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Cell-surface major vault protein promotes cancer progression through harboring mesenchymal and intermediate circulating tumor cells in hepatocellular carcinomas
    Authors: HM Lee, JW Joh, SR Seo, WT Kim, MK Kim, HS Choi, SY Kim, YJ Jang, DH Sinn, GS Choi, JM Kim, CHD Kwon, HJ Chang, DS Kim, CJ Ryu
    Sci Rep, 2017;7(1):13201.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Development of a human cardiac organoid injury model reveals innate regenerative potential
    Authors: HK Voges, RJ Mills, DA Elliott, RG Parton, ER Porrello, JE Hudson
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Nephron progenitor cell death elicits a limited compensatory response associated with interstitial expansion in the neonatal kidney
    Authors: SD Muthukrish, S Ryzhov, M Karolak, L Oxburgh
    Dis Model Mech, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Fast transdifferentiation of human Wharton's jelly mesenchymal stem cells into neurospheres and nerve-like cells
    Authors: AR Bonilla-Po, C Velez-Pard, M Jimenez-De
    J. Neurosci. Methods, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
    Authors: Xiu Li Ju
    Yonsei Med. J., 2017;58(1):206-216.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  47. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance
    Authors: RO Pereira, SM Tadinada, FM Zasadny, KJ Oliveira, KMP Pires, A Olvera, J Jeffers, R Souvenir, R Mcglauflin, A Seei, T Funari, H Sesaki, MJ Potthoff, CM Adams, EJ Anderson, ED Abel
    EMBO J., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. TMPRSS4 promotes cancer stem cell traits by regulating CLDN1 in hepatocellular carcinoma
    Authors: S Mahati, D Bolati, Y Yang, R Mao, H Zhang, Y Bao
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Large, Diverse Population Cohorts of hiPSCs and Derived Hepatocyte-like Cells Reveal Functional Genetic Variation at Blood Lipid-Associated Loci
    Authors: EE Pashos, Y Park, X Wang, A Raghavan, W Yang, D Abbey, DT Peters, J Arbelaez, M Hernandez, N Kuperwasse, W Li, Z Lian, Y Liu, W Lv, SL Lytle-Gabb, DH Marchadier, P Rogov, J Shi, KJ Slovik, IM Stylianou, L Wang, R Yan, X Zhang, S Kathiresan, SA Duncan, TS Mikkelsen, EE Morrisey, DJ Rader, CD Brown, K Musunuru
    Cell Stem Cell, 2017;20(4):558-570.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Directed differentiation of human induced pluripotent stem cells into functional cholangiocyte-like cells
    Authors: F Sampazioti, MC de Brito, I Geti, A Bertero, NR Hannan, L Vallier
    Nat Protoc, 2017;12(4):814-827.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of M�ller Glia-Derived Progenitor Cells in the Avian Retina
    Authors: L Todd, L Suarez, C Quinn, AJ Fischer
    Stem Cells, 2017;0(0):.
    Species: Chicken
    Sample Types: In Vivo
    Applications: In Vivo
  52. Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB
    Authors: NA Guadagno, C Moriconi, V Licursi, E D'Acunto, PS Nisi, N Carucci, A De Jaco, E Cacci, R Negri, G Lupo, E Miranda
    Neurobiol. Dis., 2017;103(0):32-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Eros is a novel transmembrane protein that controls the phagocyte respiratory burst and is essential for innate immunity
    Authors: DC Thomas, S Clare, JM Sowerby, M Pardo, JK Juss, DA Goulding, L van der We, D Storistean, A Prakash, M Espéli, S Flint, JC Lee, K Hoenderdos, L Kane, K Harcourt, S Mukhopadhy, Y Umrania, R Antrobus, JA Nathan, DJ Adams, A Bateman, JS Choudhary, PA Lyons, AM Condliffe, ER Chilvers, G Dougan, KG Smith
    J. Exp. Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex
    Authors: E Ercan, JM Han, A Di Nardo, K Winden, MJ Han, L Hoyo, A Saffari, A Leask, DH Geschwind, M Sahin
    J. Exp. Med, 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
    Authors: AG Kotini, CJ Chang, A Chow, H Yuan, TC Ho, T Wang, S Vora, A Solovyov, C Husser, M Olszewska, J Teruya-Fel, D Perumal, VM Klimek, A Spyridonid, RK Rampal, L Silverman, EP Reddy, E Papaemmanu, S Parekh, BD Greenbaum, CS Leslie, MG Kharas, EP Papapetrou
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy
    Authors: R Horibe, Y Hirohashi, T Asano, T Mariya, T Suzuki, A Takaya, H Saijo, Y Shionoya, T Kubo, M Nakatsugaw, T Kanaseki, T Tsukahara, K Watanabe, E Atsuyama, S Toji, H Hirano, T Hasegawa, H Takahashi, N Sato, T Torigoe
    PLoS ONE, 2017;12(3):e0171460.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia
    Authors: R Allison, JR Edgar, G Pearson, T Rizo, T Newton, S Günther, F Berner, J Hague, JW Connell, J Winkler, J Lippincott, C Beetz, B Winner, E Reid
    J. Cell Biol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells
    Authors: T Johansen, C Krabbe, SI Schmidt, AM Serrano, M Meyer
    Stem Cells Int, 2017;2017(0):9605432.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence
    Authors: N Rahman, PM Brauer, L Ho, T Usenko, M Tewary, JC Zúñiga-Pfl, PW Zandstra
    Nat Commun, 2017;8(0):15380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Prolonged inhibition of inflammation in osteoarthritis by triamcinolone acetonide released from a polyester amide microsphere platform
    Authors: I Rudnik-Jan, S Colen, J Berard, S Plomp, I Que, M van Rijen, N Woike, A Egas, G van Osch, E van Maarse, K Messier, A Chan, J Thies, L Creemers
    J Control Release, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling
    Authors: KB McCauley, F Hawkins, M Serra, DC Thomas, A Jacob, DN Kotton
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. In Vitro Micropatterned Human Pluripotent Stem Cell Test (�P-hPST) for Morphometric-Based Teratogen Screening
    Authors: J Xing, Y Cao, Y Yu, H Li, Z Song, H Yu
    Sci Rep, 2017;7(1):8491.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Self-crosslinking and injectable hyaluronic acid/RGD-functionalized pectin hydrogel for cartilage tissue engineering
    Authors: F Chen, Y Ni, B Liu, T Zhou, C Yu, Y Su, X Zhu, X Yu, Y Zhou
    Carbohydr Polym, 2017;166(0):31-44.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Bone marrow drives central nervous system regeneration after radiation injury
    Authors: J Dietrich, N Baryawno, N Nayyar, YK Valtis, B Yang, I Ly, A Besnard, N Severe, KU Gustafsson, OC Andronesi, TT Batchelor, A Sahay, DT Scadden
    J. Clin. Invest., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Circumferential Esophageal Replacement by a Tissue-engineered Substitute Using Mesenchymal Stem Cells: An Experimental Study in Mini Pigs
    Authors: J Catry, M Luong-Nguy, L Arakelian, T Poghosyan, P Bruneval, T Domet, L Michaud, R Sfeir, F Gottrand, J Larghero, V Vanneaux, P Cattan
    Cell Transplant, 2017;26(12):1831-1839.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells
    Authors: DJ Tischfield, J Kim, SA Anderson
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells
    Authors: KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima
    Stem Cell Reports, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Low extracellular potassium prolongs repolarization and evokes early afterdepolarization in human induced pluripotent stem cell-derived cardiomyocytes
    Authors: J Kuusela, K Larsson, D Shah, C Prajapati, K Aalto-Setä
    Biol Open, 2017;6(6):777-784.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK
    Authors: M Bhogal, CN Lwin, XY Seah, E Murugan, K Adnan, SJ Lin, G Peh, JS Mehta
    PLoS ONE, 2017;12(10):e0184824.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Targeting the Wnt pathway and cancer stem cells with anti-progastrin humanized antibodies: a major breakthrough for K-RAS mutated colorectal cancer treatment
    Authors: A Prieur, M Cappellini, G Habif, MP Lefranc, T Mazard, E Morency, JM Pascussi, M Flaceliere, N Cahuzac, B Vire, B Dubuc, A Durochat, P Liaud, J Ollier, C Pfeiffer, S Poupeau, V Saywell, C Planque, E Assenat, F Bibeau, JF Bourgaux, P Pujol, A Sézeur, M Ychou, D Joubert
    Clin. Cancer Res., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. A CARP-1 functional mimetic loaded vitamin E-TPGS micellar nano-formulation for inhibition of renal cell carcinoma
    Authors: VT Cheriyan, HO Alsaab, S Sekhar, C Stieber, P Kesharwani, S Sau, M Muthu, LA Polin, E Levi, AK Iyer, AK Rishi
    Oncotarget, 2017;8(62):104928-104945.
    Applications: Bioassay
  72. A cell-autonomous positive-signaling circuit associated with the PDGF-NO-ID4-regulatory axis in glioblastoma cells
    Authors: K Eun, HM Jeon, SO Kim, SH Choi, SY Lee, X Jin, SC Kim, H Kim
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Transplantation of Human Embryonic Stem Cell-Derived Retinal Cells into the Subretinal Space of a Non-Human Primate
    Authors: JR Chao, DA Lamba, TR Klesert, A Torre, A Hoshino, RJ Taylor, A Jayabalu, AL Engel, TH Khuu, RK Wang, M Neitz, J Neitz, TA Reh
    Transl Vis Sci Technol, 2017;6(3):4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Nutritional modulation of mouse and human liver bud growth through a branched-amino acid metabolism
    Authors: H Koike, RR Zhang, Y Ueno, K Sekine, YW Zheng, T Takebe, H Taniguchi
    Development, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration
    Authors: JS Saini, B Corneo, JD Miller, TR Kiehl, Q Wang, NC Boles, TA Blenkinsop, JH Stern, S Temple
    Cell Stem Cell, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017;12(4):e0175095.
    Species: Chicken
    Sample Types: Whole Embryo
    Applications: Bioassay
  77. Combining Injectable Plasma Scaffold with Mesenchymal Stem/Stromal Cells for Repairing Infarct Cavity after Ischemic Stroke
    Authors: H Zhang, F Sun, J Wang, L Xie, C Yang, M Pan, B Shao, GY Yang, SH Yang, Q ZhuGe, K Jin
    Aging Dis, 2017;8(2):203-214.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. An FAK-YAP-mTOR Signaling Axis Regulates Stem Cell-Based Tissue Renewal in Mice
    Authors: JK Hu, W Du, SJ Shelton, MC Oldham, CM DiPersio, OD Klein
    Cell Stem Cell, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Cografting astrocytes improves cell therapeutic outcomes in a Parkinson's disease model
    Authors: JJ Song, SM Oh, OC Kwon, N Wulnansari, HS Lee, MY Chang, E Lee, W Sun, SE Lee, S Chang, H An, CJ Lee, SH Lee
    J. Clin. Invest., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction
    Authors: A De Pauw, E Andre, B Sekkali, C Bouzin, H Esfahani, N Barbier, A Loriot, C De Smet, L Vanhoutte, S Moniotte, B Gerber, V di Mauro, D Catalucci, O Feron, D Hilfiker-K, JL Balligand
    JCI Insight, 2017;2(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Increased susceptibility to a? toxicity in neuronal cultures derived from familial Azheimer's disease (PSEN1-A246E) induced pluripotent stem cells
    Authors: Enrique Armijo
    Neurosci. Lett, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages
    Authors: L Zhu, A Gomez-Dura, G Saretzki, S Jin, K Tilgner, D Melguizo-S, G Anyfantis, J Al-Aama, L Vallier, P Chinnery, M Lako, L Armstrong
    J. Cell Biol., 2016;215(2):187-202.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Capturing the biology of disease severity in a PSC-based model of familial dysautonomia
    Authors: N Zeltner, F Fattahi, NC Dubois, N Saurat, F Lafaille, L Shang, B Zimmer, J Tchieu, MA Soliman, G Lee, JL Casanova, L Studer
    Nat. Med., 2016;22(12):1421-1427.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Intra-laboratory validated human cell-based in vitro vasculogenesis/angiogenesis test with serum-free medium
    Authors: T Toimela
    Reprod. Toxicol, 2016;0(0):.
    Species: Human
    Sample Types:
  86. Fibroblast growth factor (FGF) signaling regulates transforming growth factor beta (TGF?)-dependent smooth muscle cell phenotype modulation
    Sci Rep, 2016;6(0):33407.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
    Authors: Xiaoguang Fang
    J. Exp. Med, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Derivation of chicken induced pluripotent stem cells tolerant to Newcastle disease virus-induced lysis through multiple rounds of infection
    Authors: Leonardo Susta
    Virol. J, 2016;13(1):205.
    Species: Chicken
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition
    Authors: Young Dong Yoo
    EMBO Rep, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Mural-Endothelial cell-cell interactions stabilize the developing zebrafish dorsal aorta
    Authors: Amber N Stratman
    Development, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Ureteral reconstruction with reinforced collagen scaffolds in a porcine model
    Authors: Wout Feitz
    J Tissue Eng Regen Med, 2016;0(0):.
    Applications: Bioassay
  92. iPS-derived neural progenitor cells from PPMS patients reveal defect in myelin injury response
    Authors: Stephen J Crocker
    Exp. Neurol., 2016;288(0):114-121.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Engulfed cadherin fingers are polarized junctional structures between collectively migrating endothelial�cells
    Nat. Cell Biol., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Skeletal muscle atrophy is induced by Fbxw7? via atrogene upregulation
    Authors: Kyungshin Shin
    Cell Biol. Int, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
    Authors: Robert Thomas
    Biotechnol. Prog., 2016;32(1):215-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. The Semaphorin 4D-RhoA-Akt Signal Cascade Regulates Enamel Matrix Secretion in Coordination with Cell Polarization During Ameloblast Differentiation
    J Bone Miner Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity
    Authors: Ivan Carcamo-Or
    Cell Stem Cell, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Biomimetic Calcium Phosphate/Polyelectrolyte Multilayer Coatings for Sequential Delivery of Multiple Biological Factors
    Authors: E Jacobs
    J Biomed Mater Res A, 2016;0(0):.
  99. Improved neurological outcome by intramuscular injection of human amniotic fluid derived stem cells in a muscle denervation model.
    Authors: Chen C, Cheng F, Su H, Sheu M, Lu Z, Chiang C, Yang D, Sheehan J, Pan H
    PLoS ONE, 2015;10(5):e0124624.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Mitochondrial control by DRP1 in brain tumor initiating cells.
    Authors: Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, Dombrowski S, Huang Z, Fang X, Shi Y, Ferguson A, Kashatus D, Bao S, Rich J
    Nat Neurosci, 2015;18(4):501-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer.
    Authors: Wu, Bo, Cao, Xiaoming, Liang, Xuezhi, Zhang, Xuhui, Zhang, Wei, Sun, Guang, Wang, Dongwen
    PLoS ONE, 2015;10(1):e0117510.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Histone Chaperone HIRA in Regulation of Transcription Factor RUNX1.
    Authors: Majumder A, Syed K, Joseph S, Scambler P, Dutta D
    J Biol Chem, 2015;290(21):13053-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. mTOR inhibition improves fibroblast growth factor receptor targeting in hepatocellular carcinoma.
    Authors: Scheller, T, Hellerbrand, C, Moser, C, Schmidt, K, Kroemer, A, Brunner, S M, Schlitt, H J, Geissler, E K, Lang, S A
    Br J Cancer, 2015;112(5):841-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Endophilin marks and controls a clathrin-independent endocytic pathway.
    Authors: Boucrot E, Ferreira A, Almeida-Souza L, Debard S, Vallis Y, Howard G, Bertot L, Sauvonnet N, McMahon H
    Nature, 2015;517(7535):460-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Cellular Responses Modulated by FGF-2 Adsorbed on Albumin/Heparin Layer-by-Layer Assemblies.
    Authors: Kumorek M, Kubies D, Filova E, Houska M, Kasoju N, Mazl Chanova E, Matejka R, Kryslova M, Bacakova L, Rypacek F
    PLoS ONE, 2015;10(5):e0125484.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  106. The schizophrenia risk gene product miR-137 alters presynaptic plasticity.
    Authors: Siegert S, Seo J, Kwon E, Rudenko A, Cho S, Wang W, Flood Z, Martorell A, Ericsson M, Mungenast A, Tsai L
    Nat Neurosci, 2015;18(7):1008-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Resveratrol ameliorates the maturation process of beta-cell-like cells obtained from an optimized differentiation protocol of human embryonic stem cells.
    Authors: Pezzolla D, Lopez-Beas J, Lachaud C, Dominguez-Rodriguez A, Smani T, Hmadcha A, Soria B
    PLoS ONE, 2015;10(3):e0119904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Temporal and embryonic lineage-dependent regulation of human vascular SMC development by NOTCH3.
    Authors: Granata A, Bernard W, Zhao N, McCafferty J, Lilly B, Sinha S
    Stem Cells Dev, 2015;24(7):846-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Nerve growth factor and proNGF simultaneously promote symmetric self-renewal, quiescence, and epithelial to mesenchymal transition to enlarge the breast cancer stem cell compartment.
    Authors: Tomellini E, Touil Y, Lagadec C, Julien S, Ostyn P, Ziental-Gelus N, Meignan S, Lengrand J, Adriaenssens E, Polakowska R, Le Bourhis X
    Stem Cells, 2015;33(2):342-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Prolonged and tunable residence time using reversible covalent kinase inhibitors.
    Authors: Bradshaw J, McFarland J, Paavilainen V, Bisconte A, Tam D, Phan V, Romanov S, Finkle D, Shu J, Patel V, Ton T, Li X, Loughhead D, Nunn P, Karr D, Gerritsen M, Funk J, Owens T, Verner E, Brameld K, Hill R, Goldstein D, Taunton J
    Nat Chem Biol, 2015;11(7):525-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia.
    Authors: Chen X, Wales P, Quinti L, Zuo F, Moniot S, Herisson F, Rauf N, Wang H, Silverman R, Ayata C, Maxwell M, Steegborn C, Schwarzschild M, Outeiro T, Kazantsev A
    PLoS ONE, 2015;10(1):e0116919.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
    Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
    Nat Commun, 2015;6(0):6576.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain.
    Authors: Deverman B, Pravdo P, Simpson B, Kumar S, Chan K, Banerjee A, Wu W, Yang B, Huber N, Pasca S, Gradinaru V
    Nat Biotechnol, 2015;34(2):204-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. The in vitro generation of lung and airway progenitor cells from human pluripotent stem cells.
    Authors: Huang S, Green M, de Carvalho A, Mumau M, Chen Y, D'Souza S, Snoeck H
    Nat Protoc, 2015;10(3):413-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
    Authors: Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J
    Nat Med, 2015;21(5):530-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Enhanced SMAD1 Signaling Contributes to Impairments of Early Development in CFC-iPSCs.
    Authors: Han K, Kim S, Kim D, Choi J, Im I, Hwang K, Kim C, Lee B, Yoo H, Han Y
    Stem Cells, 2015;33(5):1447-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Early intervention for spinal cord injury with human induced pluripotent stem cells oligodendrocyte progenitors.
    Authors: All A, Gharibani P, Gupta S, Bazley F, Pashai N, Chou B, Shah S, Resar L, Cheng L, Gearhart J, Kerr C
    PLoS ONE, 2015;10(1):e0116933.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. The evidence of glioblastoma heterogeneity.
    Authors: Soeda, Akio, Hara, Akira, Kunisada, Takahiro, Yoshimura, Shin-ich, Iwama, Toru, Park, Deric M
    Sci Rep, 2015;5(0):7979.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Robust derivation of epicardium and its differentiated smooth muscle cell progeny from human pluripotent stem cells.
    Authors: Iyer D, Gambardella L, Bernard W, Serrano F, Mascetti V, Pedersen R, Talasila A, Sinha S
    Development, 2015;142(8):1528-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa.
    Authors: Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J
    J Invest Dermatol, 2014;134(5):1246-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
    Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
    PLoS ONE, 2014;9(12):e116114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Real-time discrimination between proliferation and neuronal and astroglial differentiation of human neural stem cells.
    Authors: Lee, Rimi, Kim, Il-Sun, Han, Nalae, Yun, Seokhwan, Park, Kook In, Yoo, Kyung-Hw
    Sci Rep, 2014;4(0):6319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy.
    Authors: Yan K, Wu Q, Yan D, Lee C, Rahim N, Tritschler I, DeVecchio J, Kalady M, Hjelmeland A, Rich J
    Genes Dev, 2014;28(10):1085-100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study.
    Authors: Zheng G, Huang L, Tong H, Shu Q, Hu Y, Ge M, Deng K, Zhang L, Zou B, Cheng B, Xu J
    Respir Res, 2014;15(0):39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Transcriptional profiling of adult neural stem-like cells from the human brain.
    Authors: Sandberg C, Vik-Mo E, Behnan J, Helseth E, Langmoen I
    PLoS ONE, 2014;9(12):e114739.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Targeted inversion and reversion of the blood coagulation factor 8 gene in human iPS cells using TALENs.
    Authors: Park, Chul-Yon, Kim, Jungeun, Kweon, Jiyeon, Son, Jeong Sa, Lee, Jae Souk, Yoo, Jeong-Eu, Cho, Sung-Rae, Kim, Jong-Hoo, Kim, Jin-Soo, Kim, Dong-Woo
    Proc Natl Acad Sci U S A, 2014;111(25):9253-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Hypoxic conditioned medium from human amniotic fluid-derived mesenchymal stem cells accelerates skin wound healing through TGF-beta/SMAD2 and PI3K/Akt pathways.
    Authors: Jun E, Zhang Q, Yoon B, Moon J, Lee G, Park G, Kang P, Lee J, Kim A, You S
    Int J Mol Sci, 2014;15(1):605-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Tissue-engineered vascular grafts created from human induced pluripotent stem cells.
    Authors: Sundaram S, One J, Siewert J, Teodosescu S, Zhao L, Dimitrievska S, Qian H, Huang A, Niklason L
    Stem Cells Transl Med, 2014;3(12):1535-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Adult human nasal mesenchymal-like stem cells restore cochlear spiral ganglion neurons after experimental lesion.
    Authors: Bas E, Van De Water T, Lumbreras V, Rajguru S, Goss G, Hare J, Goldstein B
    Stem Cells Dev, 2014;23(5):502-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells.
    Authors: Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S
    Stem Cells, 2014;32(5):1337-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
    Authors: Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, Moser C, Shaleh H, Thornburgh S, Walters I, Roberts L
    PLoS ONE, 2014;9(4):e92273.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. High efficient differentiation of functional hepatocytes from porcine induced pluripotent stem cells.
    Authors: Ao, Ying, Mich-Basso, Jocelyn, Lin, Bo, Yang, Lei
    PLoS ONE, 2014;9(6):e100417.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10.
    Authors: Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, Tamada T, Sugiura H, Harigae H, Ichinose M
    Mol Cell Biol, 2014;34(15):2848-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. CoCl2, a mimic of hypoxia, induces formation of polyploid giant cells with stem characteristics in colon cancer.
    Authors: Lopez-Sanchez L, Jimenez C, Valverde A, Hernandez V, Penarando J, Martinez A, Lopez-Pedrera C, Munoz-Castaneda J, De la Haba-Rodriguez J, Aranda E, Rodriguez-Ariza A
    PLoS ONE, 2014;9(6):e99143.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2.
    Authors: van Gastel N, Stegen S, Stockmans I, Moermans K, Schrooten J, Graf D, Luyten F, Carmeliet G
    Stem Cells, 2014;32(9):2407-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Genetic background drives transcriptional variation in human induced pluripotent stem cells.
    Authors: Rouhani, Foad, Kumasaka, Natsuhik, de Brito, Miguel C, Bradley, Allan, Vallier, Ludovic, Gaffney, Daniel
    PLoS Genet, 2014;10(6):e1004432.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
    Authors: Falcon B, Swearingen M, Gough W, Lee L, Foreman R, Uhlik M, Hanson J, Lee J, McClure D, Chintharlapalli S
    PLoS ONE, 2014;9(9):e106901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Resolving cancer-stroma interfacial signalling and interventions with micropatterned tumour-stromal assays.
    Authors: Shen K, Luk S, Hicks D, Elman J, Bohr S, Iwamoto Y, Murray R, Pena K, Wang F, Seker E, Weissleder R, Yarmush M, Toner M, Sgroi D, Parekkadan B
    Nat Commun, 2014;5(0):5662.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation.
    Authors: Hirata, Naoya, Yamada, Shigeru, Shoda, Takuji, Kurihara, Masaaki, Sekino, Yuko, Kanda, Yasunari
    Nat Commun, 2014;5(0):4806.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Histone hyperacetylation up-regulates protein kinase Cdelta in dopaminergic neurons to induce cell death: relevance to epigenetic mechanisms of neurodegeneration in Parkinson disease.
    Authors: Jin H, Kanthasamy A, Harischandra D, Kondru N, Ghosh A, Panicker N, Anantharam V, Rana A, Kanthasamy A
    J Biol Chem, 2014;289(50):34743-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Mesenchymal stromal cells support the viability and differentiation of follicular lymphoma-infiltrating follicular helper T-cells.
    Authors: Brady M, Hilchey S, Hyrien O, Spence S, Bernstein S
    PLoS ONE, 2014;9(5):e97597.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Autophagy modulates SNCA/alpha-synuclein release, thereby generating a hostile microenvironment.
    Authors: Poehler A, Xiang W, Spitzer P, May V, Meixner H, Rockenstein E, Chutna O, Outeiro T, Winkler J, Masliah E, Klucken J
    Autophagy, 2014;10(12):2171-92.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  143. FGFR2 is amplified in the NCI-H716 colorectal cancer cell line and is required for growth and survival.
    Authors: Mathur, Anjili, Ware, Christop, Davis, Lenora, Gazdar, Adi, Pan, Bo-Sheng, Lutterbach, Bart
    PLoS ONE, 2014;9(6):e98515.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Reprogramming activity of NANOGP8, a NANOG family member widely expressed in cancer.
    Authors: Palla, A R, Piazzolla, D, Abad, M, Li, H, Dominguez, O, Schonthaler, H B, Wagner, E F, Serrano, M
    Oncogene, 2014;33(19):2513-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
    Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
    J Clin Invest, 2014;124(1):425-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: cell culture
  146. Canine epidermal neural crest stem cells: characterization and potential as therapy candidate for a large animal model of spinal cord injury.
    Authors: Gericota B, Anderson J, Mitchell G, Borjesson D, Sturges B, Nolta J, Sieber-Blum M
    Stem Cells Transl Med, 2014;3(3):334-45.
    Species: Canine
    Sample Types: Whole Tissue
    Applications: Bioassay
  147. Inner ear hair cell-like cells from human embryonic stem cells.
    Authors: Ronaghi, Mohammad, Nasr, Marjan, Ealy, Megan, Durruthy-Durruthy, Robert, Waldhaus, Joerg, Diaz, Giovanni, Joubert, Lydia-Ma, Oshima, Kazuo, Heller, Stefan
    Stem Cells Dev, 2014;23(11):1275-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Chondrogenesis of infrapatellar fat pad derived adipose stem cells in 3D printed chitosan scaffold.
    Authors: Ye K, Felimban R, Traianedes K, Moulton S, Wallace G, Chung J, Quigley A, Choong P, Myers D
    PLoS ONE, 2014;9(6):e99410.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Cis-acting DNA sequence at a replication origin promotes repeat expansion to fragile X full mutation.
    Authors: Gerhardt J, Zaninovic N, Zhan Q, Madireddy A, Nolin S, Ersalesi N, Yan Z, Rosenwaks Z, Schildkraut C
    J Cell Biol, 2014;206(5):599-607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Long non-coding RNAs as surrogate indicators for chemical stress responses in human-induced pluripotent stem cells.
    Authors: Tani, Hidenori, Onuma, Yasuko, Ito, Yuzuru, Torimura, Masaki
    PLoS ONE, 2014;9(8):e106282.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.
    Authors: Flierl A, Oliveira L, Falomir-Lockhart L, Mak S, Hesley J, Soldner F, Arndt-Jovin D, Jaenisch R, Langston J, Jovin T, Schule B
    PLoS ONE, 2014;9(11):e112413.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Specific ablation of Nampt in adult neural stem cells recapitulates their functional defects during aging.
    Authors: Stein L, Imai S
    EMBO J, 2014;33(12):1321-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment.
    Authors: Rodin S, Antonsson L, Niaudet C, Simonson O, Salmela E, Hansson E, Domogatskaya A, Xiao Z, Damdimopoulou P, Sheikhi M, Inzunza J, Nilsson A, Baker D, Kuiper R, Sun Y, Blennow E, Nordenskjold M, Grinnemo K, Kere J, Betsholtz C, Hovatta O, Tryggvason K
    Nat Commun, 2014;5(0):3195.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Selective calcium sensitivity in immature glioma cancer stem cells.
    Authors: Wee S, Niklasson M, Marinescu V, Segerman A, Schmidt L, Hermansson A, Dirks P, Forsberg-Nilsson K, Westermark B, Uhrbom L, Linnarsson S, Nelander S, Andang M
    PLoS ONE, 2014;9(12):e115698.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Generation of a vascularized and functional human liver from an iPSC-derived organ bud transplant.
    Authors: Takebe, Takanori, Zhang, Ran-Ran, Koike, Hiroyuki, Kimura, Masaki, Yoshizawa, Emi, Enomura, Masahiro, Koike, Naoto, Sekine, Keisuke, Taniguchi, Hideki
    Nat Protoc, 2014;9(2):396-409.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. alpha-Synuclein oligomers impair neuronal microtubule-kinesin interplay.
    Authors: Prots I, Veber V, Brey S, Campioni S, Buder K, Riek R, Bohm K, Winner B
    J Biol Chem, 2013;288(30):21742-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Enrichment and characterization of human dermal stem/progenitor cells by intracellular granularity.
    Authors: Shim, Joong Hy, Lee, Tae Ryon, Shin, Dong Woo
    Stem Cells Dev, 2013;22(8):1264-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. ADAM12 is expressed in the tumour vasculature and mediates ectodomain shedding of several membrane-anchored endothelial proteins.
    Authors: Frohlich C, Klitgaard M, Noer J, Kotzsch A, Nehammer C, Kronqvist P, Berthelsen J, Blobel C, Kveiborg M, Albrechtsen R, Wewer U
    Biochem J, 2013;452(1):97-109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Production of hepatocyte-like cells from human pluripotent stem cells.
    Authors: Hannan, Nicholas, Segeritz, Charis-P, Touboul, Thomas, Vallier, Ludovic
    Nat Protoc, 2013;8(2):430-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons.
    Authors: Hong, Weimin C, Amara, Susan G
    FASEB J, 2013;27(8):2995-3007.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Chemotherapy activates cancer-associated fibroblasts to maintain colorectal cancer-initiating cells by IL-17A.
    Authors: Lotti, Fiorenza, Jarrar, Awad M, Pai, Rish K, Hitomi, Masahiro, Lathia, Justin, Mace, Adam, Gantt, Gerald A, Sukhdeo, Kumar, DeVecchio, Jennifer, Vasanji, Amit, Leahy, Patrick, Hjelmeland, Anita B, Kalady, Matthew, Rich, Jeremy N
    J Exp Med, 2013;210(13):2851-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Enhanced filopodium formation and stem-like phenotypes in a novel metastatic head and neck cancer cell model.
    Authors: Chen Y, Huang W, Chang S, Chang K, Kao S, Lo J, Su P
    Oncol Rep, 2013;30(6):2829-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Distinct effects of ligand-induced PDGFRalpha and PDGFRbeta signaling in the human rhabdomyosarcoma tumor cell and stroma cell compartments.
    Authors: Ehnman M, Missiaglia E, Folestad E, Selfe J, Strell C, Thway K, Brodin B, Pietras K, Shipley J, Ostman A, Eriksson U
    Cancer Res, 2013;73(7):2139-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012;7(4):e34965.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility.
    Authors: Cheung C, Bernardo AS, Trotter MW
    Nat. Biotechnol., 2012;30(2):165-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Non-canonical TAF complexes regulate active promoters in human embryonic stem cells.
    Authors: Maston G, Zhu L, Chamberlain L, Lin L, Fang M, Green M
    Elife, 2012;1(0):e00068.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. The endothelial cell line bEnd.3 maintains human pluripotent stem cells.
    Authors: Joubin, Katherin, Richardson, Amelia, Novoa, Natalia, Tu, Edmund, Tomishima, Mark J
    Stem Cells Dev, 2012;21(12):2312-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
    Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
    Blood, 2012;120(19):4104-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c.
    Authors: Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, Martin I
    Stem Cells, 2012;30(7):1455-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation.
    Authors: Pirotte S, Lamour V, Lambert V, Alvarez Gonzalez ML, Ormenese S, Noel A, Mottet D, Castronovo V, Bellahcene A
    Blood, 2011;117(8):2515-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Differentiation potential of human postnatal mesenchymal stem cells, mesoangioblasts, and multipotent adult progenitor cells reflected in their transcriptome and partially influenced by the culture conditions.
    Authors: Roobrouck VD, Clavel C, Jacobs SA, Ulloa-Montoya F, Crippa S, Sohni A, Roberts SJ, Luyten FP, Van Gool SW, Sampaolesi M, Delforge M, Luttun A, Verfaillie CM
    Stem Cells, 2011;29(5):871-82.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  173. Endogenous expression of matriptase in neural progenitor cells promotes cell migration and neuron differentiation.
    Authors: Fang JD, Chou HC, Tung HH
    J. Biol. Chem., 2011;286(7):5667-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  174. CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres.
    Authors: Walter D, Satheesha S, Albrecht P, Bornhauser BC, D'Alessandro V, Oesch SM, Rehrauer H, Leuschner I, Koscielniak E, Gengler C, Moch H, Bernasconi M, Niggli FK, Schafer BW
    PLoS ONE, 2011;6(5):e19506.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Specification of transplantable astroglial subtypes from human pluripotent stem cells.
    Authors: Krencik R, Weick JP, Liu Y, Zhang ZJ, Zhang SC
    Nat. Biotechnol., 2011;29(6):528-34.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.
    Authors: Roelandt P, Pauwelyn KA, Sancho-Bru P
    PLoS ONE, 2010;5(8):e12101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Expansion/Differentiation
  177. Selection and characterization of a human neutralizing antibody to human fibroblast growth factor-2.
    Authors: Tao J, Xiang JJ, Li D, Deng N, Wang H, Gong YP
    Biochem. Biophys. Res. Commun., 2010;394(3):767-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Improvement in disability after alemtuzumab treatment of multiple sclerosis is associated with neuroprotective autoimmunity.
    Authors: Jones JL, Anderson JM, Phuah CL, Fox EJ, Selmaj K, Margolin D, Lake SL, Palmer J, Thompson SJ, Wilkins A, Webber DJ, Compston DA, Coles AJ
    Brain, 2010;133(0):2232-47.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Enoxaparin improves the course of dextran sodium sulfate-induced colitis in syndecan-1-deficient mice.
    Authors: Floer M, Gotte M, Wild MK, Heidemann J, Gassar ES, Domschke W, Kiesel L, Luegering A, Kucharzik T
    Am. J. Pathol., 2010;176(1):146-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
    Authors: Chng Z, Teo A, Pedersen RA, Vallier L
    Cell Stem Cell, 2010;6(1):59-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome.
    Authors: Carvajal-Vergara X, Sevilla A, D'Souza SL
    Nature, 2010;465(7299):808-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.
    Authors: Yang MH, Hsu DS, Wang HW
    Nat. Cell Biol., 2010;12(10):982-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Growth factor regulation of growth factors in articular chondrocytes.
    Authors: Shi S, Mercer S, Eckert GJ, Trippel SB
    J. Biol. Chem., 2009;284(11):6697-704.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Establishment of a transitory dorsal-biased window of localized Ca2+ signaling in the superficial epithelium following the mid-blastula transition in zebrafish embryos.
    Authors: Ma LH, Webb SE, Chan CM, Zhang J, Miller AL
    Dev. Biol., 2009;327(1):143-57.
    Species: Zebrafish
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Functional coexpression of Interleukin (IL)-7 and its receptor (IL-7R) on Hodgkin and Reed-Sternberg cells: Involvement of IL-7 in tumor cell growth and microenvironmental interactions of Hodgkin's lymphoma.
    Authors: Cattaruzza L, Gloghini A, Olivo K, Di Francia R, Lorenzon D, De Filippi R, Carbone A, Colombatti A, Pinto A, Aldinucci D
    Int. J. Cancer, 2009;125(5):1092-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Similar expression to FGF (Sef) inhibits fibroblast growth factor-induced tumourigenic behaviour in prostate cancer cells and is downregulated in aggressive clinical disease.
    Authors: Darby S, Murphy T, Thomas H, Robson CN, Leung HY, Mathers ME, Gnanapragasam VJ
    Br. J. Cancer, 2009;101(11):1891-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Mitogen-activated protein kinase-signaling regulates the ability of Muller glia to proliferate and protect retinal neurons against excitotoxicity.
    Authors: Fischer AJ, Scott MA, Ritchey ER, Sherwood P
    Glia, 2009;57(14):1538-52.
    Species: Chicken
    Sample Types: In Vivo
    Applications: In Vivo
  188. Biphasic induction of Pdx1 in mouse and human embryonic stem cells can mimic development of pancreatic beta-cells.
    Authors: Bernardo AS, Cho CH, Mason S, Docherty HM, Pedersen RA, Vallier L, Docherty K
    Stem Cells, 2009;27(2):341-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Characterization of human skin-derived mesenchymal stem cell proliferation rate in different growth conditions.
    Authors: Riekstina U, Muceniece R, Cakstina I, Muiznieks I, Ancans J
    Cytotechnology, 2008;58(3):153-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Musashi1 RNA-binding protein regulates oligodendrocyte lineage cell differentiation and survival.
    Authors: Dobson NR, Zhou YX, Flint NC, Armstrong RC
    Glia, 2008;56(3):318-30.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  192. MDR1 expression identifies human melanoma stem cells.
    Authors: Keshet GI, Goldstein I, Itzhaki O, Cesarkas K, Shenhav L, Yakirevitch A, Treves AJ, Schachter J, Amariglio N, Rechavi G
    Biochem. Biophys. Res. Commun., 2008;368(4):930-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. High-throughput screening assay for the identification of compounds regulating self-renewal and differentiation in human embryonic stem cells.
    Authors: Desbordes SC, Placantonakis DG, Ciro A, Socci ND, Lee G, Djaballah H, Studer L
    Cell Stem Cell, 2008;2(6):602-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage.
    Authors: Elkabetz Y, Panagiotakos G, Al Shamy G, Socci ND, Tabar V, Studer L
    Genes Dev., 2008;22(2):152-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. A CXCL5- and bFGF-dependent effect of PDGF-B-activated fibroblasts in promoting trafficking and differentiation of bone marrow-derived mesenchymal stem cells.
    Authors: Nedeau AE, Bauer RJ, Gallagher K, Chen H, Liu ZJ, Velazquez OC
    Exp. Cell Res., 2008;314(11):2176-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Lineage selection of functional and cryopreservable human embryonic stem cell-derived neurons.
    Authors: Ladewig J, Koch P, Endl E, Meiners B, Opitz T, Couillard-Despres S, Aigner L, Brustle O
    Stem Cells, 2008;26(7):1705-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures.
    Authors: Rao RC, Boyd J, Padmanabhan R, Chenoweth JG, McKay RD
    Stem Cells, 2008;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Distinctions between fetal and adult human platelet-derived growth factor-responsive neural precursors.
    Authors: Chojnacki A, Kelly JJ, Hader W, Weiss S
    Ann. Neurol., 2008;64(2):127-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Specific heparan sulfate structures modulate FGF10-mediated submandibular gland epithelial morphogenesis and differentiation.
    Authors: Patel VN, Likar KM, Zisman-Rozen S, Cowherd SN, Lassiter KS, Sher I, Yates EA, Turnbull JE, Ron D, Hoffman MP
    J. Biol. Chem., 2008;283(14):9308-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Human embryonic stem cells in culture possess primary cilia with hedgehog signaling machinery.
    Authors: Kiprilov EN, Awan A, Desprat R, Velho M, Clement CA, Byskov AG, Andersen CY, Satir P, Bouhassira EE, Christensen ST, Hirsch RE
    J. Cell Biol., 2008;180(5):897-904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.
    Authors: McLean AB, D&amp;amp;apos;Amour KA, Jones KL, Krishnamoorthy M, Kulik MJ, Reynolds DM, Sheppard AM, Liu H, Xu Y, Baetge EE, Dalton S
    Stem Cells, 2007;25(1):29-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Long-term maintenance of brain tumor stem cell properties under at non-adherent and adherent culture conditions.
    Authors: Inagaki A, Soeda A, Oka N, Kitajima H, Nakagawa J, Motohashi T, Kunisada T, Iwama T
    Biochem. Biophys. Res. Commun., 2007;361(3):586-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Qualification of embryonal carcinoma 2102Ep as a reference for human embryonic stem cell research.
    Authors: Josephson R, Ording CJ, Liu Y, Shin S, Lakshmipathy U, Toumadje A, Love B, Chesnut JD, Andrews PW, Rao MS, Auerbach JM
    Stem Cells, 2007;25(2):437-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Short-term BMP-4 treatment initiates mesoderm induction in human embryonic stem cells.
    Authors: Zhang P, Li J, Tan Z, Wang C, Liu T, Chen L, Yong J, Jiang W, Sun X, DU L, Ding M, Deng H
    Blood, 2007;111(4):1933-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
    Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
    J. Biol. Chem., 2007;282(43):31643-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
    Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
    Nature, 2007;450(7171):825-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Role for amplification and expression of glypican-5 in rhabdomyosarcoma.
    Authors: Williamson D, Selfe J, Lu YJ, Pritchard-Jones K, Murai K, Jones P, Workman P, Shipley J
    Cancer Res., 2007;67(1):57-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Conditional gene expression in human embryonic stem cells.
    Authors: Vallier L, Alexander M, Pedersen R
    Stem Cells, 2007;25(6):1490-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Differentiation of ES cells into cerebellar neurons.
    Authors: Salero E, Hatten ME
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(8):2997-3002.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation.
    Authors: Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH
    Diabetes, 2007;57(1):158-66.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.
    Authors: Patel VN, Knox SM, Likar KM, Lathrop CA, Hossain R, Eftekhari S, Whitelock JM, Elkin M, Vlodavsky I, Hoffman MP
    Development, 2007;134(23):4177-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. A large-scale proteomic analysis of human embryonic stem cells.
    Authors: Schulz TC, Swistowska AM, Liu Y
    BMC Genomics, 2007;8(0):478.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. New cell lines from mouse epiblast share defining features with human embryonic stem cells.
    Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
    Nature, 2007;448(7150):196-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Fractalkine, a CX3C chemokine, as a mediator of ocular angiogenesis.
    Authors: You JJ, Yang CH, Huang JS, Chen MS, Yang CM
    Invest. Ophthalmol. Vis. Sci., 2007;48(11):5290-8.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling.
    Authors: Wang L, Schulz TC, Sherrer ES, Dauphin DS, Shin S, Nelson AM, Ware CB, Zhan M, Song CZ, Chen X, Brimble SN, McLean A, Galeano MJ, Uhl EW, D'Amour KA, Chesnut JD, Rao MS, Blau CA, Robins AJ
    Blood, 2007;110(12):4111-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats.
    Authors: Kobayashi T, Ahlenius H, Thored P, Kobayashi R, Kokaia Z, Lindvall O
    Stroke, 2006;37(9):2361-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Heterodimerization of FGF-receptor 1 and PDGF-receptor-alpha: a novel mechanism underlying the inhibitory effect of PDGF-BB on FGF-2 in human cells.
    Authors: Faraone D, Aguzzi MS, Ragone G, Russo K, Capogrossi MC, Facchiano A
    Blood, 2006;107(5):1896-902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Isolation of a novel population of multipotent adult stem cells from human hair follicles.
    Authors: Yu H, Fang D, Kumar SM, Li L, Nguyen TK, Acs G, Herlyn M, Xu X
    Am. J. Pathol., 2006;168(6):1879-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
    Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
    Br. J. Haematol., 2006;135(5):703-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
    Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
    Am. J. Pathol., 2006;168(2):529-41.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  223. Protective effects of neurotrophic factors on tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of murine adrenal chromaffin cell line tsAM5D.
    Authors: Murata T, Tsuboi M, Hikita K, Kaneda N
    J. Biol. Chem., 2006;281(32):22503-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
    Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
    Glia, 2006;53(8):845-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
    Authors: Narazaki M, Tosato G
    Blood, 2006;107(10):3892-901.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  226. Re-growth of catecholaminergic fibers and protection of cholinergic spinal cord neurons in spinal repaired rats.
    Authors: Lee YS, Lin CY, Robertson RT, Yu J, Deng X, Hsiao I, Lin VW
    Eur. J. Neurosci., 2006;23(3):693-702.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  227. Pretreatment of adult bone marrow mesenchymal stem cells with cardiomyogenic growth factors and repair of the chronically infarcted myocardium.
    Authors: Bartunek J, Croissant JD, Wijns W, Gofflot S, de Lavareille A, Vanderheyden M, Kaluzhny Y, Mazouz N, Willemsen P, Penicka M, Mathieu M, Homsy C, De Bruyne B, McEntee K, Lee IW, Heyndrickx GR
    Am. J. Physiol. Heart Circ. Physiol., 2006;292(2):H1095-104.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  229. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc.
    Authors: Nakayama T, Mutsuga N, Tosato G
    Blood, 2006;109(4):1363-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Expression of leukemia inhibitory factor and its receptors is increased during differentiation of human embryonic stem cells.
    Authors: Aghajanova L, Skottman H, Stromberg AM, Inzunza J, Lahesmaa R, Hovatta O
    Fertil. Steril., 2006;86(4):1193-209.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Neural conversion of human embryonic stem cell colonies in the presence of fibroblast growth factor-2.
    Authors: Benzing C, Segschneider M, Leinhaas A, Itskovitz-Eldor J, Brustle O
    Neuroreport, 2006;17(16):1675-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration.
    Authors: Li Y, Fan J, Chen M, Li W, Woodley DT
    J. Invest. Dermatol., 2006;126(9):2096-105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm.
    Authors: Lindsley RC, Gill JG, Kyba M, Murphy TL, Murphy KM
    Development, 2006;133(19):3787-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs (hESCs) to support hESC self-renewal.
    Authors: Greber B, Lehrach H, Adjaye J
    Stem Cells, 2006;25(2):455-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Embryonic stem cell-derived neuron models of Parkinson's disease exhibit delayed neuronal death.
    Authors: Yamashita H, Nakamura T, Takahashi T, Nagano Y, Hiji M, Hirabayashi T, Amano T, Yagi T, Sakai N, Kohriyama T, Matsumoto M
    J. Neurochem., 2006;98(1):45-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.
    Authors: Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D
    J. Biol. Chem., 2006;281(49):37844-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Clonal amniotic fluid-derived stem cells express characteristics of both mesenchymal and neural stem cells.
    Authors: Tsai MS, Hwang SM, Tsai YL, Cheng FC, Lee JL, Chang YJ
    Biol. Reprod., 2005;74(3):545-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
    Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2005;203(1):35-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Prox1 promotes lineage-specific expression of fibroblast growth factor (FGF) receptor-3 in lymphatic endothelium: a role for FGF signaling in lymphangiogenesis.
    Authors: Shin JW, Min M, Larrieu-Lahargue F, Canron X, Kunstfeld R, Nguyen L, Henderson JE, Bikfalvi A, Detmar M, Hong YK
    Mol. Biol. Cell, 2005;17(2):576-84.
    Species: Human
    Sample Types: Whole Cells
  240. Transitin, a nestin-related intermediate filament, is expressed by neural progenitors and can be induced in Muller glia in the chicken retina.
    Authors: Fischer AJ, Omar G
    J. Comp. Neurol., 2005;484(1):1-14.
    Species: Chicken
    Sample Types: In Vivo
    Applications: In Vivo
  241. Novel regulators of kidney development from the tips of the ureteric bud.
    Authors: Schmidt-Ott KM, Yang J, Chen X, Wang H, Paragas N, Mori K, Li JY, Lu B, Costantini F, Schiffer M, Bottinger E, Barasch J
    J. Am. Soc. Nephrol., 2005;16(7):1993-2002.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Bioassay
  242. Application of plasmid DNA encoding IL-18 diminishes development of herpetic stromal keratitis by antiangiogenic effects.
    Authors: Kim B, Lee S, Suvas S, Rouse BT
    J. Immunol., 2005;175(1):509-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy.
    Authors: Bagley RG, Weber W, Rouleau C, Teicher BA
    Cancer Res., 2005;65(21):9741-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. FGFR2b signaling regulates ex vivo submandibular gland epithelial cell proliferation and branching morphogenesis.
    Authors: Steinberg Z, Myers C, Heim VM, Lathrop CA, Rebustini IT, Stewart JS, Larsen M, Hoffman MP
    Development, 2005;132(6):1223-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Different aspects of gliosis in retinal Muller glia can be induced by CNTF, insulin, and FGF2 in the absence of damage.
    Authors: Fischer AJ, Omar G, Eubanks J, McGuire CR, Dierks BD, Reh TA
    Mol. Vis., 2004;10(0):973-86.
    Species: Chicken
    Sample Types: In Vivo
    Applications: In Vivo
  246. Growth differentiation factor-9 and stem cell factor promote primordial follicle formation in the hamster: modulation by follicle-stimulating hormone.
    Authors: Wang J, Roy SK
    Biol. Reprod., 2004;70(3):577-85.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Angiostatin-induced inhibition of endothelial cell proliferation/apoptosis is associated with the down-regulation of cell cycle regulatory protein cdk5.
    Authors: Sharma MR, Tuszynski GP, Sharma MC
    J. Cell. Biochem., 2004;91(2):398-409.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  248. High-level expression of functional chemokine receptor CXCR4 on human neural precursor cells.
    Authors: Ni HT, Hu S, Sheng WS, Olson JM, Cheeran MC, Chan AS, Lokensgard JR, Peterson PK
    Brain Res. Dev. Brain Res., 2004;152(2):159-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004;104(2):314-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.
    Authors: Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J
    Arthritis Rheum., 2004;50(8):2521-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
    Authors: Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
    Cancer Res., 2003;63(4):887-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Binding Assay
  252. Sef inhibits fibroblast growth factor signaling by inhibiting FGFR1 tyrosine phosphorylation and subsequent ERK activation.
    Authors: Kovalenko D, Yang X, Nadeau RJ, Harkins LK, Friesel R
    J. Biol. Chem., 2003;278(16):14087-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity.
    Authors: Yi M, Sakai T, Fassler R, Ruoslahti E
    Proc. Natl. Acad. Sci. U.S.A., 2003;100(20):11435-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  254. Extracellular domain of TGFbeta type III receptor inhibits angiogenesis and tumor growth in human cancer cells.
    Authors: Bandyopadhyay A, Zhu Y, Malik SN, Kreisberg J, Brattain MG, Sprague EA, Luo J, Lopez-Casillas F, Sun LZ
    Oncogene, 2002;21(22):3541-51.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  255. Regulation of alpha(v)beta3 and alpha5beta1 integrin receptors by basic fibroblast growth factor and platelet-derived growth factor-BB in intrasynovial flexor tendon cells.
    Authors: Harwood FL, Goomer RS, Gelberman RH, Silva MJ, Amiel D
    Wound Repair Regen, 1999;7(5):381-8.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. What receptors does FGF basic bind?

  2. Does human FGF basic show activity on mouse cells?
    • Yes, it does. The bioassay uses NR-6 mouse fibroblast cells.  There is 95% homology between the human and mouse protein and 98% homology between the human and mouse receptor.

View all Proteins and Enzyme FAQs

Animal-Free Recombinant Proteins

Reviews for Recombinant Human FGF basic (146 aa) Protein

Average Rating: 4.7 (Based on 12 Reviews)

5 Star
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4 Star
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3 Star
8.33%
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Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 07/27/2018
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 07/07/2018
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 05/10/2017
Application: Cell proliferation

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 04/26/2017

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 04/12/2017
Application: fibronection ELISA of cell culture supernatants

FGF-2 was used with EGF to induce proliferation and EMT


Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 04/09/2017
Application: Cell migration/motility

Growth of MDA-MB-231 spheroids in serum-free condition in the absence (A) or presence (B) of Recombinant Human FGF (#233-FB) after 72 hours. Medium: RPMI + 2% B-27 supplement + 1% L-glutamine + 1% Pen/Strep.


Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 12/15/2016
Application: Stem/Immune cell maintenance or differentiation

Supplement to human embryonic stem cell medium for differentiation.


Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 08/17/2016
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Recombinant protein used to induced spheres from olfactory stem cells and thr result was always excellent

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 08/03/2016
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 05/18/2016
Application: Cell proliferation
Reason for Rating: These cultures grew as expected with no observable variability due to growth factors.

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 01/19/2016
Application: In vitro bioactivity in cell culture

Recombinant Human FGF basic (146 aa) Protein
By Anonymous on 10/26/2015
Application: Cell Culture

Recombinant human FGF basic (146 aa) protein was used for growing human NSCs at the concentration of 20 ng/ml.