Recombinant Human TGF-beta 3 Protein, CF

A New rhTGF-beta 3 is Now Available! It is CHO-expressed and competitively priced.
New Product 8420-B3/CF.
(59 citations)   
  • Purity
    >97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
  • Endotoxin Level
    <0.01 EU per 1 μg of the protein by the LAL method.
  • Activity
    Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. Tsang, M. et al. (1995) Cytokine 7:389. The ED50 for this effect is 0.01-0.04 ng/mL.
    The specific activity of recombinant human TGF-beta 3 is approximately 2.2 x 104 IU/μg, which is calibrated against recombinant human TGF-beta 3 WHO International Standard (NIBSC code: 09/234).
  • Source
    Spodoptera frugiperda, Sf 21 (baculovirus)-derived Ala301-Ser412 (Tyr340Phe)
  • Accession #
  • N-terminal Sequence
    Analysis
    Ala301
  • Structure / Form
    Disulfide-linked homodimer
  • Predicted Molecular Mass
    12.7 kDa (monomer)
  • SDS-PAGE
    12 kDa, reducing conditions
    24 kDa, non-reducing conditions
Carrier Free
What does CF mean?
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
243-B3/CF
 
243-B3
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA.
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute 2 µg vials at 20 µg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin. Reconstitute 10 µg or larger vials at 50 µg/mL in sterile 4 mM HCl.
Reconstitution Reconstitute at 20 μg/mL in sterile 4 mM HCl containing 1 mg/mL human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Data Images
Recombinant Human TGF-beta 3 (Catalog # 243-B3/CF) inhibits Recombinant Mouse IL‑4 (Catalog # 404-ML) induced proliferation in the HT-2 mouse T cell line. The ED50 for this effect is 0.01-0.04 ng/mL.
1 μg/lane of Recombinant Human TGF-beta 3 was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing single bands at 12 kDa and 24 kDa, respectively.
Background: TGF-beta 3

TGF­ beta 3 (transforming growth factor-beta 3) is a member of a TGF­-beta superfamily subgroup that is defined by their structural and functional similarities (1-5). TGF-beta 3 and its closely related proteins, TGF-beta 1 and ­-beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial­-mesenchymal transition (4, 6, 7). The non-redundant biological effects of TGF-­ beta 3 include involvement in palatogenesis, chondrogenesis, and pulmonary development (1, 2, 7-9). Human TGF-­ beta 3 cDNA encodes a 412 amino acid (aa) precursor that contains a 20 aa signal peptide and a 392 aa proprotein. The proprotein is processed by a furin­like convertase to generate a 220 aa latency­associated peptide (LAP) and a 112 aa mature TGF­-beta 3 (10, 11). Mature human TGF­-beta 3 shows 100%, 99%, and 98% aa identity with mouse/dog/horse, rat, and pig TGF-­ beta 3, respectively. TGF-beta 3 is secreted as a complex with LAP. This latent form of TGF-beta 3 becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin-1, and a subset of integrins (12). TGF-beta 3 binds with high affinity to TGF-beta RII, a type II serine/threonine kinase receptor. This receptor then phosphorylates and activates type I serine/threonine kinase receptors, TGF-­ beta RI or ALK-­1, to modulate transcription through Smad phosphorylation (13-15). The divergent biological effects exerted by individual TGF-beta isoforms is dependent upon the recruitment of co-receptors (TGF-­ beta RIII and endoglin) and the subsequent initiation of Smad-­dependent or -independent signaling pathways (14, 16, 17).

  • References:
    1. Barrio, M.C. et al. (2014) Cells Tissues Organs. [Epub ahead of print; PMID 24861080].
    2. Doetschman, T. et al. (2012) Genesis 50:59.
    3. Mittl, P.R. et al. (1996) Protein Sci. 5:1261.
    4. Sporn, M.B. (2006) Cytokine Growth Factor Rev. 17:3.
    5. Wahl, S.M. et al. (2006) Immunol. Rev. 213:213.
    6. Chang, H. et al. (2002) Endocr. Rev. 23:787.
    7. Dunker, N. and K. Krieglstein (2000) Eur. J. Biochem. 267:6982.
    8. Jin, J.Z. et al. (2014) Dev. Dyn. [Epub ahead of print; PMID 25104574].
    9. Tang, Q.O. et al. (2009) Expert Opin. Biol Ther. 9:689.
    10. Derynck, R. et al. (1988) EMBO J. 7:3737.
    11. Miyazono, K. et al. (1988) J. Biol. Chem. 263:6407.
    12. Oklu, R. and R. Hesketh (2000) Biochem. J. 352 Pt 3:601.
    13. Cui, X.M. and C.F. Shuler (2000) Int. J. Dev. Biol. 44:397.
    14. de Caestecker, M. (2004) Cytokine Growth Factor Rev. 15:1.
    15. Nakajima, A. et al. (2007) Dev. Dyn. 236:791.
    16. Iwata, J. et al. (2012) J. Clin. Invest. 122:873.
    17. Gatza, C.E. et al. (2010) Cell. Signal. 22:1163.
  • Long Name:
    Transforming Growth Factor beta 3
  • Entrez Gene IDs:
    7043 (Human); 21809 (Mouse); 25717 (Rat)
  • Alternate Names:
    ARVD; FLJ16571; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor, beta 3
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

59 Citations: Showing 1 - 10
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Species
Applications
Sample Type
  1. Activin-A enhances mTOR signaling to promote aberrant chondrogenesis in fibrodysplasia ossificans progressiva
    Authors: K Hino, K Horigome, M Nishio, S Komura, S Nagata, C Zhao, Y Jin, K Kawakami, Y Yamada, A Ohta, J Toguchida, M Ikeya
    J. Clin. Invest., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  2. Culture-expanded allogenic adipose tissue-derived stem cells attenuate cartilage degeneration in an experimental rat osteoarthritis model
    Authors: L Mei, B Shen, P Ling, S Liu, J Xue, F Liu, H Shao, J Chen, A Ma, X Liu
    PLoS ONE, 2017;12(4):e0176107.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  3. Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs
    Authors: JM Brunger, A Zutshi, VP Willard, CA Gersbach, F Guilak
    Stem Cell Reports, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  4. Neurotoxic reactive astrocytes are induced by activated microglia
    Authors: SA Liddelow, KA Guttenplan, LE Clarke, FC Bennett, CJ Bohlen, L Schirmer, ML Bennett, AE Mnch, WS Chung, TC Peterson, DK Wilton, A Frouin, BA Napier, N Panicker, M Kumar, MS Buckwalter, DH Rowitch, VL Dawson, TM Dawson, B Stevens, BA Barres
    Nature, 2017;541(7638):481-487.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  5. Effect of microgravity on the mesenchymal stem cell characteristics of limbal fibroblasts
    Authors: SI Pao, KH Chien, HT Lin, MC Tai, JT Chen, CM Liang
    J Chin Med Assoc, 2017;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  6. Evaluation of Three Devices for the Isolation of the Stromal Vascular Fraction from Adipose Tissue and for ASC Culture: A Comparative Study
    Authors: J Rodriguez, AS Pratta, N Abbassi, H Fabre, F Rodriguez, C Debard, J Adobati, F Boucher, F Mallein-Ge, C Auxenfans, O Damour, A Mojallal
    Stem Cells Int, 2017;2017(0):9289213.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  7. Dynamics of chromatin accessibility during TGF-?-induced EMT of Ras-transformed mammary gland epithelial cells
    Authors: M Arase, Y Tamura, N Kawasaki, K Isogaya, R Nakaki, A Mizutani, S Tsutsumi, H Aburatani, K Miyazono, D Koinuma
    Sci Rep, 2017;7(1):1166.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  8. Characterization of single cell derived cultures of periosteal progenitor cells to ensure the cell quality for clinical application
    Authors: S Stich, A Loch, SJ Park, T Häupl, J Ringe, M Sittinger
    PLoS ONE, 2017;12(5):e0178560.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  9. TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
    Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
    PLoS ONE, 2017;12(5):e0177771.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  10. Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells
    Authors: HH Wu, OK Lee
    Stem Cell Res Ther, 2017;8(1):117.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  11. Mesenchymal stem cells from cortical bone demonstrate increased clonal incidence, potency, and developmental capacity compared to their bone marrow-derived counterparts
    J Tissue Eng, 2016;7(0):2041731416661.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  12. Anatomically shaped tissue-engineered cartilage with tunable and inducible anticytokine delivery for biological joint resurfacing
    Proc Natl Acad Sci USA, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  13. Aberrant Transforming Growth Factor-? Activation Recruits Mesenchymal Stem Cells During Prostatic Hyperplasia
    Stem Cells Transl Med, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  14. Characterization and Immunomodulatory Effects of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells
    PLoS ONE, 2016;11(12):e0167442.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  15. Generation, Characterization, and Multilineage Potency of Mesenchymal-Like Progenitors Derived from Equine Induced Pluripotent Stem Cells.
    Authors: Lepage S, Nagy K, Sung H, Kandel R, Nagy A, Koch T
    Stem Cells Dev, 2016;25(1):80-9.
    Species: Equine
    Sample Type: Whole Cells
    Application: Bioassay
  16. Means of enhancing bone fracture healing: optimal cell source, isolation methods and acoustic stimulation
    BMC Biotechnol, 2016;16(1):89.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  17. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  18. Canine Platelet Lysate Is Inferior to Fetal Bovine Serum for the Isolation and Propagation of Canine Adipose Tissue- and Bone Marrow-Derived Mesenchymal Stromal Cells.
    Authors: Russell K, Gibson T, Chong A, Co C, Koch T
    PLoS ONE, 2015;10(9):e0136621.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  19. Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA.
    Authors: Belzile, Jean-Phi, Stark, Thomas J, Yeo, Gene W, Spector, Deborah
    J Virol, 2014;88(8):4021-39.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  20. Human bone marrow-derived mesenchymal stem cells display enhanced clonogenicity but impaired differentiation with hypoxic preconditioning.
    Authors: Boyette, Lisa B, Creasey, Olivia A, Guzik, Lynda, Lozito, Thomas, Tuan, Rocky S
    Stem Cells Transl Med, 2014;3(2):241-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  21. microRNA-495 inhibits chondrogenic differentiation in human mesenchymal stem cells by targeting Sox9.
    Authors: Lee S, Yoon D, Paik S, Lee K, Jang Y, Lee J
    Stem Cells Dev, 2014;23(15):1798-808.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  22. Human fetal and adult bone marrow-derived mesenchymal stem cells use different signaling pathways for the initiation of chondrogenesis.
    Authors: Brady K, Dickinson S, Guillot P, Polak J, Blom A, Kafienah W, Hollander A
    Stem Cells Dev, 2014;23(5):541-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  23. Semaphorin 3A induces mesenchymal-stem-like properties in human periodontal ligament cells.
    Authors: Wada, Naohisa, Maeda, Hidefumi, Hasegawa, Daigaku, Gronthos, Stan, Bartold, Peter Ma, Menicanin, Danijela, Fujii, Shinsuke, Yoshida, Shinichi, Tomokiyo, Atsushi, Monnouchi, Satoshi, Akamine, Akifumi
    Stem Cells Dev, 2014;23(18):2225-36.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  24. Analysis of the effects of five factors relevant to in vitro chondrogenesis of human mesenchymal stem cells using factorial design and high throughput mRNA-profiling.
    Authors: Jakobsen R, Ostrup E, Zhang X, Mikkelsen T, Brinchmann J
    PLoS ONE, 2014;9(5):e96615.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  25. Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.
    Authors: Liu G, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla R, Goebl A, Aizawa E, Kim N, Kim J, Dubova I, Li Y, Ren R, Benner C, del Sol A, Bueren J, Trujillo J, Surralles J, Cappelli E, Dufour C, Esteban C, Izpisua Belmonte J
    Nat Commun, 2014;5(0):4330.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  26. Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage.
    Authors: Brunger J, Huynh N, Guenther C, Perez-Pinera P, Moutos F, Sanchez-Adams J, Gersbach C, Guilak F
    Proc Natl Acad Sci U S A, 2014;111(9):E798-806.
    Species: N/A
    Sample Type: Complex Sample Type
    Application: Bioassay
  27. Sox9-regulated miRNA-574-3p inhibits chondrogenic differentiation of mesenchymal stem cells.
    Authors: Guerit D, Philipot D, Chuchana P, Toupet K, Brondello J, Mathieu M, Jorgensen C, Noel D
    PLoS ONE, 2014;8(4):e62582.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  28. CD146 expression on mesenchymal stem cells is associated with their vascular smooth muscle commitment.
    Authors: Espagnolle N, Guilloton F, Deschaseaux F, Gadelorge M, Sensebe L, Bourin P
    J Cell Mol Med, 2014;18(1):104-14.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  29. Induction of immunomodulatory monocytes by human mesenchymal stem cell-derived hepatocyte growth factor through ERK1/2.
    Authors: Chen P, Liu K, Hsu P, Wei C, Bai C, Ho L, Sytwu H, Yen B
    J Leukoc Biol, 2014;96(2):295-303.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  30. Protein-releasing polymeric scaffolds induce fibrochondrocytic differentiation of endogenous cells for knee meniscus regeneration in sheep.
    Authors: Lee C, Rodeo S, Fortier L, Lu C, Erisken C, Mao J
    Sci Transl Med, 2014;6(266):266ra171.
    Species: Sheep
    Sample Type: Whole Cells
    Application: Bioassay
  31. In vitro model suggests oxidative stress involved in keratoconus disease.
    Authors: Karamichos D, Hutcheon A, Rich C, Trinkaus-Randall V, Asara J, Zieske J
    Sci Rep, 2014;4(0):4608.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  32. Interleukin-6 disrupts blood-testis barrier through inhibiting protein degradation or activating phosphorylated ERK in Sertoli cells.
    Authors: Zhang H, Yin Y, Wang G, Liu Z, Liu L, Sun F
    Sci Rep, 2014;4(0):4260.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  33. A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells.
    Authors: Karamichos D, Funderburgh M, Hutcheon A, Zieske J, Du Y, Wu J, Funderburgh J
    PLoS ONE, 2014;9(1):e86260.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  34. Molecular characterization of prospectively isolated multipotent mesenchymal progenitors provides new insight into the cellular identity of mesenchymal stem cells in mouse bone marrow.
    Authors: Qian H, Badaloni A, Chiara F, Stjernberg J, Polisetti N, Nihlberg K, Consalez G, Sigvardsson M
    Mol Cell Biol, 2013;33(4):661-77.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  35. Bone marrow stromal and vascular smooth muscle cells have chemosensory capacity via bitter taste receptor expression.
    Authors: Lund, Troy C, Kobs, Amanda J, Kramer, Ashley, Nyquist, Mick, Kuroki, Marcos T, Osborn, John, Lidke, Diane S, Low-Nam, Shalini, Blazar, Bruce R, Tolar, Jakub
    PLoS ONE, 2013;8(3):e58945.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  36. MicroRNA-based promotion of human neuronal differentiation and subtype specification.
    Authors: Stappert L, Borghese L, Roese-Koerner B, Weinhold S, Koch P, Terstegge S, Uhrberg M, Wernet P, Brustle O
    PLoS ONE, 2013;8(3):e59011.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  37. TGF-beta-induced apoptosis of B-cell lymphoma Ramos cells through reduction of MS4A1/CD20.
    Authors: Kawabata K, Ehata S, Komuro A, Takeuchi K, Miyazono K
    Oncogene, 2013;32(16):2096-106.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  38. Human embryonic stem cell-derived mesenchymal stroma cells (hES-MSCs) engraft in vivo and support hematopoiesis without suppressing immune function: implications for off-the shelf ES-MSC therapies.
    Authors: Li O, Tormin A, Sundberg B, Hyllner J, Le Blanc K, Scheding S
    PLoS ONE, 2013;8(1):e55319.
    Species: Human
    Sample Type: Whole Cells
    Application: Cell Culture Substrate
  39. Primary Mesenchymal Stem and Progenitor Cells from Bone Marrow Lack Expression of CD44 Protein.
    Authors: Qian H, Le Blanc K, Sigvardsson M
    J. Biol. Chem., 2012;287(31):25795-807.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  40. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors.
    Authors: Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J
    Nature, 2012;487(7408):505-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  41. Transforming growth factor Beta 3 is required for excisional wound repair in vivo.
    Authors: Le M, Naridze R, Morrison J, Biggs L, Rhea L, Schutte B, Kaartinen V, Dunnwald M
    PLoS ONE, 2012;7(10):e48040.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  42. Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth.
    Authors: Castonguay R, Werner ED, Matthews RG, Presman E, Mulivor AW, Solban N, Sako D, Pearsall RS, Underwood KW, Seehra J, Kumar R, Grinberg AV
    J. Biol. Chem., 2011;286(34):30034-46.
    Species: Human
    Sample Type: Recombinant Protein
    Application: Surface Plasmon Resonance
  43. Age-related changes in rat bone-marrow mesenchymal stem cell plasticity.
    Authors: Asumda FZ, Chase PB
    BMC Cell Biol., 2011;12(0):44.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  44. An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.
    Authors: Gregory PA, Bracken CP, Smith E, Bert AG, Wright JA, Roslan S, Morris M, Wyatt L, Farshid G, Lim YY, Lindeman GJ, Shannon MF, Drew PA, Khew-Goodall Y, Goodall GJ
    Mol. Biol. Cell, 2011;22(10):1686-98.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  45. Expression of the HGF receptor c-met by macrophages in experimental autoimmune encephalomyelitis.
    Authors: Moransard M, Sawitzky M, Fontana A, Suter T
    Glia, 2010;58(5):559-71.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  46. Isolation and propagation of enteric neural crest progenitor cells from mouse embryonic stem cells and embryos.
    Authors: Kawaguchi J, Nichols J, Gierl MS, Faial T, Smith A
    Development, 2010;137(5):693-704.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  47. Cell contact, prostaglandin E(2) and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25(High) forkhead box P3+ regulatory T cells.
    Authors: English K, Ryan JM, Tobin L, Murphy MJ, Barry FP, Mahon BP
    Clin. Exp. Immunol., 2009;156(1):149-60.
    Species: Human
    Sample Type: Whole Cells
    Application: differentiation
  48. Transforming growth factor-beta in the brain enhances fat oxidation via noradrenergic neurons in the ventromedial and paraventricular hypothalamic nucleus.
    Authors: Fujikawa T, Matsumura S, Yamada H, Inoue K, Fushiki T
    Brain Res., 2007;1173(0):92-101.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  49. Autologous stem cell regeneration in craniosynostosis.
    Authors: Moioli EK, Clark PA, Sumner DR, Mao JJ
    Bone, 2007;42(2):332-40.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  50. Activation of transforming growth factor-beta by the integrin alphavbeta8 delays epithelial wound closure.
    Authors: Neurohr C, Nishimura SL, Sheppard D
    Am. J. Respir. Cell Mol. Biol., 2006;35(2):252-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  51. Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta.
    Authors: Nagineni CN, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2005;203(1):35-43.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  52. Derivation of midbrain dopamine neurons from human embryonic stem cells.
    Authors: Perrier AL, Tabar V, Barberi T, Rubio ME, Bruses J, Topf N, Harrison NL, Studer L
    Proc. Natl. Acad. Sci. U.S.A., 2004;101(34):12543-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  53. Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads.
    Authors: Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI
    Am. J. Respir. Cell Mol. Biol., 2004;30(6):816-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  54. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein.
    Authors: Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R
    Int. J. Dev. Biol., 2003;47(1):15-29.
    Species: Xenopus
    Sample Type: In Vivo
    Application: In Vivo
  55. Th2 cytokine regulation of type I collagen gel contraction mediated by human lung mesenchymal cells.
    Authors: Liu X, Kohyama T, Wang H, Zhu YK, Wen FQ, Kim HJ, Romberger DJ, Rennard SI
    Am. J. Physiol. Lung Cell Mol. Physiol., 2002;282(5):L1049-56.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  56. Induction of a hypertrophic growth status of coronary smooth muscle cells is associated with an overexpression of TGF-beta.
    Authors: Schmidt A, Gopfert C, Vlodavsky I, Volker W, Buddecke E
    Eur. J. Cell Biol., 2002;81(3):138-44.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  57. Transforming growth factor beta expression in human placenta and placental bed during early pregnancy.
    Authors: Simpson H, Robson SC, Bulmer JN, Barber A, Lyall F
    Placenta, 2002;23(1):44-58.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  58. Isoform specificity of commercially-available anti-TGF-beta antibodies.
    Authors: Mozes MM, Hodics T, Kopp JB
    J. Immunol. Methods, 1999;225(1):87-93.
    Species: N/A
    Sample Type: N/A
    Application: WB Ctrl
  59. TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner.
    Authors: Elias S, Schmidt A, Kannan V, Andersson J, Tegner J
    Front Immunol, 0;7(0):603.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
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Have you used Recombinant Human TGF-beta 3 Protein, CF?

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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