Recombinant Human VEGF 165 Protein

Formulations:
Catalog # Availability Size / Price Qty
293-VE-010
293-VE-050
293-VE-500
293-VE-01M
Recombinant Human VEGF 165 Protein Bioactivity
2 Images
Product Details
Citations (312)
FAQs
Supplemental Products
Reviews (23)

Recombinant Human VEGF 165 Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using HUVEC human umbilical vein endothelial cells. Conn, G. et al. (1990) Proc. Natl. Acad. Sci. USA 87:1323. The ED50 for this effect is 1-6 ng/mL.
The specific activity of recombinant human VEGF165 is approximately 1.7 x 103 U/μg, which is calibrated against recombinant human VEGF165 WHO Standard (NIBSC code: 02/286).
Source
Spodoptera frugiperda, Sf 21 (baculovirus)-derived human VEGF protein
Ala27-Arg191
Accession #
N-terminal Sequence
Analysis
Ala27
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
19.2 kDa (monomer)
SDS-PAGE
20-22 kDa, reducing conditions
39-42 kDa, non-reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

293-VE

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin. Alternatively, reconstitute at 500 μg/mL in sterile 4 mM HCl containing 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

293-VE/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with trehalose.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS. Alternatively, reconstitute at 500 μg/mL in sterile 4 mM HCl.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Bioactivity View Larger

Recombinant Human VEGF165 (Catalog # 293-VE) stimulates proliferation in HUVEC human umbilical vein endothelial cells. The ED50 is 1-6 ng/mL.

SDS-PAGE SDS-PAGE View Larger

1 μg/lane of Recombinant Human VEGF165 was resolved by SDS-PAGE with silver staining, under reducing (R) and non-reducing (NR) conditions, showing major bands at 20-22 kDa and 39-42 kDa, respectively. Multiple bands in gel are due to glycosylation.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: VEGF

Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure (4). Humans express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206 amino acids (aa) in length (4). VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). Isoforms other than VEGF121 contain basic heparin-binding regions and are not freely diffusible (4). Human VEGF165 shares 88% aa sequence identity with corresponding regions of mouse and rat, 96% with porcine, 95% with canine, and 93% with feline, equine and bovine VEGF, respectively. VEGF binds the type I transmembrane receptor tyrosine kinases VEGF R1 (also called Flt-1) and VEGF R2 (Flk-1/KDR) on endothelial cells (4). Although VEGF affinity is highest for binding to VEGF R1, VEGF R2 appears to be the primary mediator of VEGF angiogenic activity (3, 4). VEGF165 binds the semaphorin receptor, Neuropilin-1 and promotes complex formation with VEGF R2 (5). VEGF is required during embryogenesis to regulate the proliferation, migration, and survival of endothelial cells (3, 4). In adults, VEGF functions mainly in wound healing and the female reproductive cycle (3). Pathologically, it is involved in tumor angiogenesis and vascular leakage (6, 7). Circulating VEGF levels correlate with disease activity in autoimmune diseases such as rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (8). VEGF is induced by hypoxia and cytokines such as IL-1, IL-6, IL-8, oncostatin M and TNF-alpha (3, 4, 9).

References
  1. Leung, D.W. et al. (1989) Science 246:1306. 
  2. Keck, P.J. et al. (1989) Science 246:1309. 
  3. Byrne, A.M. et al. (2005) J. Cell. Mol. Med. 9:777. 
  4. Robinson, C.J. and S.E. Stringer (2001) J. Cell. Sci. 114:853.
  5. Pan, Q. et al. (2007) J. Biol. Chem. 282:24049.
  6. Weis, S.M. and D.A. Cheresh (2005) Nature 437:497.
  7. Thurston, G. (2002) J. Anat. 200:575.
  8. Carvalho, J.F. et al. (2007) J. Clin. Immunol. 27:246.
  9. Angelo, L.S. and R. Kurzrock (2007) Clin. Cancer Res. 13:2825.
Long Name
Vascular Endothelial Growth Factor
Entrez Gene IDs
7422 (Human); 22339 (Mouse); 83785 (Rat); 281572 (Bovine); 403802 (Canine); 493845 (Feline); 30682 (Zebrafish)
Alternate Names
MVCD1; VAS; vascular endothelial growth factor A; Vascular permeability factor; Vasculotropin; VEGF; VEGFA; VEGF-A; VEGFMGC70609; VPF; VPFvascular endothelial growth factor

Citations for Recombinant Human VEGF 165 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

312 Citations: Showing 1 - 10
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  1. Glycosaminoglycans from Alzheimer's disease hippocampus have altered capacities to bind and regulate growth factors activities and to bind tau
    Authors: MB Huynh, MO Ouidja, S Chantepie, G Carpentier, A Maïza, G Zhang, J Vilares, R Raisman-Vo, D Papy-Garci
    PLoS ONE, 2019;14(1):e0209573.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Development
  2. Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming
    Authors: N Muraoka, K Nara, F Tamura, H Kojima, H Yamakawa, T Sadahiro, K Miyamoto, M Isomi, S Haginiwa, H Tani, S Kurotsu, R Osakabe, S Torii, S Shimizu, H Okano, Y Sugimoto, K Fukuda, M Ieda
    Nat Commun, 2019;10(1):674.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Exosomes Derived from Human Induced Pluripotent Stem Cells-Endothelia Cells Promotes Postnatal Angiogenesis in Mice Bearing Ischemic Limbs
    Authors: M Ye, Q Ni, H Qi, X Qian, J Chen, X Guo, M Li, Y Zhao, G Xue, H Deng, L Zhang
    Int. J. Biol. Sci., 2019;15(1):158-168.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Dickkopf-1 (DKK1) promotes tumor growth via Akt-phosphorylation and independently of Wnt-axis in Barrett's associated esophageal adenocarcinoma
    Authors: O Lyros, AK Lamprecht, L Nie, R Thieme, K Götzel, M Gasparri, G Haasler, P Rafiee, R Shaker, I Gockel
    Am J Cancer Res, 2019;9(2):330-346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. The addition of a polyglutamate domain to the angiogenic QK peptide improves peptide coupling to bone graft materials leading to enhanced endothelial cell activation
    Authors: NW Pensa, AS Curry, MS Reddy, SL Bellis
    PLoS ONE, 2019;14(3):e0213592.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Ultrasonic Generation of Pulsatile and Sequential Therapeutic Delivery Profiles from Calcium-Crosslinked Alginate Hydrogels
    Authors: T Emi, K Michaud, E Orton, G Santilli, C Linh, M O'Connell, F Issa, S Kennedy
    Molecules, 2019;24(6):.
    Applications: Bioassay
  7. In-vitro binding analysis of anti-human vascular endothelial growth factor antibodies bevacizumab and aflibercept with canine, feline, and equine vascular endothelial growth factor
    Authors: LM Muellerlei, B Buxbaum, B Nell, DA Fux
    Res. Vet. Sci., 2019;124(0):233-238.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA
  8. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
    Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
    Cancer Res., 2019;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  9. Growth Factor-like Gene Regulation Is Separable from Survival and Maturation in Antibody-Secreting Cells
    Authors: S Stephenson, MA Care, I Fan, A Zougman, DR Westhead, GM Doody, RM Tooze
    J. Immunol., 2019;202(4):1287-1300.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Dual-functional gelatin-capped silver nanoparticles for antibacterial and antiangiogenic treatment of bacterial keratitis
    Authors: LJ Luo, TY Lin, CH Yao, PY Kuo, M Matsusaki, SG Harroun, CC Huang, JY Lai
    J Colloid Interface Sci, 2019;536(0):112-126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Tumorigenicity assay essential for facilitating safety studies of hiPSC-derived cardiomyocytes for clinical application
    Authors: E Ito, S Miyagawa, M Takeda, A Kawamura, A Harada, H Iseoka, S Yajima, N Sougawa, N Mochizuki-, S Yasuda, Y Sato, Y Sawa
    Sci Rep, 2019;9(1):1881.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Enhancing bioactivity, physicochemical, and pharmacokinetic properties of a nano-sized, anti-VEGFR2 Adnectin, through PASylation technology
    Authors: S Aghaabdoll, R Ahangari C, D Norouzian, F Davami, MR Asadi Kara, F Torkashvan, G Vaseghi, R Moazzami, S Latif Diza
    Sci Rep, 2019;9(1):2978.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. G protein-coupled receptors activate p38 MAPK via a non-canonical TAB1-TAB2 and TAB1-TAB3 dependent pathway in endothelial cells
    Authors: NJ Grimsey, Y Lin, R Narala, CC Rada, H Mejia-Pena, J Trejo
    J. Biol. Chem., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Rapid Production of Human VEGF-A following Intradermal Injection of Modified VEGF-A mRNA Demonstrated by Cutaneous Microdialysis in the Rabbit and Pig In Vivo
    Authors: S Pehrsson, M Hölttä, G Linhardt, RF Danielson, L Carlsson
    Biomed Res Int, 2019;2019(0):3915851.
    Species: Transgenic Rabbit
    Sample Types: Microdialysates
    Applications: Immunoassay Standard
  15. CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularisation
    Authors: S Ashraf, S Bell, C O'Leary, P Canning, I Micu, JA Fernandez, M O'Hare, P Barabas, H McCauley, DP Brazil, AW Stitt, JG McGeown, TM Curtis
    JCI Insight, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering
    Authors: Y Jang, J Choi, N Park, J Kang, M Kim, Y Kim, JH Ju
    Exp. Mol. Med., 2019;51(1):3.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair
    Authors: T Colunga, M Hayworth, S Kre beta, DM Reynolds, L Chen, KL Nazor, J Baur, AM Singh, JF Loring, M Metzger, S Dalton
    Cell Rep, 2019;26(10):2566-2579.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. A VEGF-A/SOX2/SRSF2 network controls VEGFR1 pre-mRNA alternative splicing in lung carcinoma cells
    Authors: C Abou Fayca, S Gazzeri, B Eymin
    Sci Rep, 2019;9(1):336.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis
    Authors: G Genet, K Boyé, T Mathivet, R Ola, F Zhang, A Dubrac, J Li, N Genet, L Henrique G, L Benedetti, S Künzel, L Pibouin-Fr, JL Thomas, A Eichmann
    Nat Commun, 2019;10(1):2350.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  21. Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function
    Authors: S Jauhiainen, JP Laakkonen, K Ketola, PI Toivanen, T Nieminen, T Ninchoji, AL Levonen, MU Kaikkonen, S Ylä-Herttu
    Front Physiol, 2019;10(0):224.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Effect of recombinant human vascular endothelial growth factor on testis tissue xenotransplants from prepubertal boys: a three-case study
    Authors: E Ntemou, P Kadam, S Van Laere, D Van Saen, E Vicini, E Goossens
    Reprod. Biomed. Online, 2019;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  23. Nrf2 Activator RS9 Suppresses Pathological Ocular Angiogenesis and Hyperpermeability
    Authors: S Nakamura, T Noguchi, Y Inoue, S Sakurai, A Nishinaka, Y Hida, T Masuda, Y Nakagami, N Horai, H Tsusaki, H Hara, M Shimazawa
    Invest. Ophthalmol. Vis. Sci., 2019;60(6):1943-1952.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies
    Authors: B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat
    Cell Rep, 2019;27(2):599-615.e12.
    Species: Human
    Sample Types: cell culture
    Applications: Differentiation
  25. Generation of TCR-Expressing Innate Lymphoid-like Helper Cells that Induce Cytotoxic T Cell-Mediated Anti-leukemic Cell Response
    Authors: N Ueda, Y Uemura, R Zhang, S Kitayama, S Iriguchi, Y Kawai, Y Yasui, M Tatsumi, T Ueda, TY Liu, Y Mizoro, C Okada, A Watanabe, M Nakanishi, S Senju, Y Nishimura, K Kuzushima, H Kiyoi, T Naoe, S Kaneko
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. VEGF may contribute to macrophage recruitment and M2 polarization in the decidua
    Authors: KC Wheeler, MK Jena, BS Pradhan, N Nayak, S Das, CD Hsu, DS Wheeler, K Chen, NR Nayak
    PLoS ONE, 2018;13(1):e0191040.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Extracellular anti-angiogenic proteins augment an endosomal protein trafficking pathway to reach mitochondria and execute apoptosis in HUVECs
    Authors: M Chen, T Qiu, J Wu, Y Yang, GD Wright, M Wu, R Ge
    Cell Death Differ., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Effects of concentrated growth factor on proliferation, migration, and differentiation of human dental pulp stem cells in vitro
    Authors: R Jin, G Song, J Chai, X Gou, G Yuan, Z Chen
    J Tissue Eng, 2018;9(0):2041731418817.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. ?-Escin Effectively Modulates HUVECS Proliferation and Tube Formation
    Authors: L Varinská, L Fáber, M Kello, E Petrovová, ? Balážová, P Solár, M ?oma, P Urdzík, J Mojžiš, E Švajdlenka, P Mu?aji, P Gál
    Molecules, 2018;23(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Enhancing T Cell Receptor Stability in Rejuvenated iPSC-Derived T Cells Improves Their Use in Cancer Immunotherapy
    Authors: A Minagawa, T Yoshikawa, M Yasukawa, A Hotta, M Kunitomo, S Iriguchi, M Takiguchi, Y Kassai, E Imai, Y Yasui, Y Kawai, R Zhang, Y Uemura, H Miyoshi, M Nakanishi, A Watanabe, A Hayashi, K Kawana, T Fujii, T Nakatsura, S Kaneko
    Cell Stem Cell, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. The transcription factor Vezf1 represses the expression of the antiangiogenic factor d2 in endothelial cells
    Authors: L Alabdi, M He, Q Yang, AB Norvil, H Gowher
    J. Biol. Chem., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Phorbol esters induce PLVAP expression via VEGF and additional secreted molecules in MEK1-dependent and p38, JNK and PI3K/Akt-independent manner
    Authors: BJ Hamilton, D Tse, RV Stan
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Bioassay
  33. Modified VEGF-A mRNA induces sustained multifaceted microvascular response and accelerates diabetic wound healing
    Authors: N Sun, B Ning, KM Hansson, AC Bruce, SA Seaman, C Zhang, M Rikard, CA DeRosa, CL Fraser, M Wågberg, R Fritsche-D, J Wikström, KR Chien, A Lundahl, M Hölttä, LG Carlsson, SM Peirce, S Hu
    Sci Rep, 2018;8(1):17509.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  34. Bevacizumab or fibronectin gene editing inhibits the osteoclastogenic effects of fibroblasts derived from human radicular cysts
    Authors: HC Wang, P Wang, YW Chen, Y Zhang
    Acta Pharmacol. Sin., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. IL-8 associates with a pro-angiogenic and mesenchymal subtype in glioblastoma
    Authors: S Conroy, FAE Kruyt, M Wagemakers, KPL Bhat, WFA den Dunnen
    Oncotarget, 2018;9(21):15721-15731.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. RF/6A Chorioretinal Cells Do Not Display Key Endothelial Phenotypes
    Authors: RD Makin, I Apicella, Y Nagasaka, H Kaneko, SD Turner, N Kerur, J Ambati, BD Gelfand
    Invest. Ophthalmol. Vis. Sci., 2018;59(15):5795-5802.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Curcumin inhibits hepatocellular carcinoma growth by targeting VEGF expression
    Authors: Z Pan, J Zhuang, C Ji, Z Cai, W Liao, Z Huang
    Oncol Lett, 2018;15(4):4821-4826.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Sensory neuronal sensitisation occurs through HMGB-1/ RAGE and TRPV1 in high glucose conditions
    Authors: SM Bestall, RP Hulse, Z Blackley, M Swift, N Ved, K Paton, N Beazley-Lo, DO Bates, LF Donaldson
    J. Cell. Sci., 2018;0(0):.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  39. A Linc1405/Eomes Complex Promotes Cardiac Mesoderm Specification and Cardiogenesis
    Authors: X Guo, Y Xu, Z Wang, Y Wu, J Chen, G Wang, C Lu, W Jia, J Xi, S Zhu, Z Jiapaer, X Wan, Z Liu, S Gao, J Kang
    Cell Stem Cell, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. VEGF165b, a splice variant of VEGF-A, promotes lung tumor progression and escape from anti-angiogenic therapies through a ?1 integrin/VEGFR autocrine loop
    Authors: A Boudria, C Abou Fayca, T Jia, S Gout, M Keramidas, C Didier, N Lemaître, S Manet, JL Coll, AC Toffart, D Moro-Sibil, C Albiges-Ri, V Josserand, E Faurobert, C Brambilla, E Brambilla, S Gazzeri, B Eymin
    Oncogene, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Preclinical Evaluation of ADVM-022, a Novel Gene Therapy Approach to Treating Wet Age-Related Macular Degeneration
    Authors: R Grishanin, B Vuillemeno, P Sharma, A Keravala, J Greengard, C Gelfman, M Blumenkran, M Lawrence, W Hu, S Kiss, M Gasmi
    Mol. Ther., 2018;0(0):.
    Species: Primate - Chlorocebus sabaeus (Green Monkey)
    Sample Types: Vitreous Humor
    Applications: ELISA (Capture)
  42. Preparation of iPS cell-derived CD31+ endothelial cells using three-dimensional suspension culture
    Authors: S Masuda, K Matsuura, T Shimizu
    Regen Ther, 2018;9(0):1-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Tbx1 represses Mef2c gene expression and is correlated with histone 3 deacetylation of the anterior heart field enhancer
    Authors: LS Pane, FG Fulcoli, A Cirino, A Altomonte, R Ferrentino, M Bilio, A Baldini
    Dis Model Mech, 2018;11(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability
    Authors: GA Rodrigues, M Mason, LA Christie, C Hansen, LM Hernandez, J Burke, KA Luhrs, TC Hohman
    Invest. Ophthalmol. Vis. Sci., 2018;59(15):5836-5846.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  45. Inhibition of Endothelial SCUBE2 (Signal Peptide-CUB-EGF Domain-Containing Protein 2), a Novel VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) Coreceptor, Suppresses Tumor Angiogenesis
    Authors: YC Lin, CY Liu, R Kannagi, RB Yang
    Arterioscler. Thromb. Vasc. Biol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys
    Authors: MQ Wentink, HMW Verheul, AW Griffioen, KA Schafer, S McPherson, RJ Early, HJ van der Vl, TD de Gruijl
    Vaccine, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies
    Authors: R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Applications: Bioassay
  48. VEGFR (Vascular Endothelial Growth Factor Receptor) Inhibition Induces Cardiovascular Damage via Redox-Sensitive Processes
    Authors: KB Neves, FJ Rios, L van der Me, R Alves-Lope, AC Cameron, M Volpe, AC Montezano, C Savoia, RM Touyz
    Hypertension, 2018;71(4):638-647.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis
    Authors: H Alsaffar, N Martino, JP Garrett, AP Adam
    Am. J. Physiol., Cell Physiol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Analytical and functional similarity of Amgen biosimilar ABP 215 to bevacizumab
    Authors: N Seo, A Polozova, M Zhang, Z Yates, S Cao, H Li, S Kuhns, G Maher, HJ McBride, J Liu
    MAbs, 2018;0(0):1-58.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Capture
  51. MicroRNA-134 inhibits osteosarcoma angiogenesis and proliferation by targeting the VEGFA/VEGFR1 pathway
    Authors: L Zhang, Z Lv, J Xu, C Chen, Q Ge, P Li, D Wei, Z Wu, X Sun
    FEBS J., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Investigating Colorimetric Protein Array Assay Schemes for Detection of Recurrence of Bladder Cancer
    Authors: S Gogalic, U Sauer, S Doppler, C Preininger
    Biosensors (Basel), 2018;8(1):.
    Species: Human
    Sample Types: Urine
    Applications: Array Development
  53. The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
    Authors: K Koefoed, J Skat-Rørda, P Andersen, CB Warzecha, M Pye, TA Andersen, KD Ajbro, E Bendsen, M Narimatsu, F Vilhardt, LB Pedersen, JL Wrana, RH Anderson, K Møllgård, ST Christense, LA Larsen
    Sci Rep, 2018;8(1):9542.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Engineered ligand-based VEGFR antagonists with increased receptor binding affinity more effectively inhibit angiogenesis
    Authors: S Kapur, AP Silverman, AZ Ye, N Papo, D Jindal, MS Blumenkran, JR Cochran
    Bioeng Transl Med, 2017;2(1):81-91.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  55. Novel Small Molecule JP-153 Targets the Src-FAK-Paxillin Signaling Complex to Inhibit VEGF-Induced Retinal Angiogenesis
    Authors: Charles R Yates
    Mol. Pharmacol., 2017;91(1):1-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Vascular endothelial growth factor-A165b ameliorates outer-retinal barrier and vascular dysfunction in the diabetic retina
    Authors: N Ved, RP Hulse, SM Bestall, LF Donaldson, JW Bainbridge, DO Bates
    Clin. Sci, 2017;0(0):.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  57. Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis
    Authors: LA Murray, DM Habiel, M Hohmann, A Camelo, H Shang, Y Zhou, AL Coelho, X Peng, M Gulati, B Crestani, MA Sleeman, T Mustelin, MW Moore, C Ryu, AD Osafo-Addo, JA Elias, CG Lee, B Hu, JD Herazo-May, DA Knight, CM Hogaboam, EL Herzog
    JCI Insight, 2017;2(16):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Monitoring response to anti-angiogenic mTOR inhibitor therapy in vivo using (111)In-bevacizumab
    Authors: N Patel, S Able, D Allen, E Fokas, B Cornelisse, FV Gleeson, AL Harris, KA Vallis
    EJNMMI Res, 2017;7(1):49.
    Applications: Western Blot
  59. Vascular Endothelial Growth Factor in Cartilage Development and Osteoarthritis
    Authors: M Nagao, JL Hamilton, R Kc, AD Berendsen, X Duan, CW Cheong, X Li, HJ Im, BR Olsen
    Sci Rep, 2017;7(1):13027.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  60. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  61. The angiostatic molecule Multimerin 2 is processed by MMP-9 to allow sprouting angiogenesis
    Authors: E Andreuzzi, R Colladel, R Pellicani, G Tarticchio, R Cannizzaro, P Spessotto, B Bussolati, A Brossa, P De Paoli, V Canzonieri, RV Iozzo, A Colombatti, M Mongiat
    Matrix Biol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Vertical bone regeneration using rhBMP-2 and VEGF
    Authors: L Schorn, C Sproll, M Ommerborn, C Naujoks, NR Kübler, R Depprich
    Head Face Med, 2017;13(1):11.
    Species: Porcine
    Sample Types: In Vivo
  63. Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3
    Authors: H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng
    Sci Rep, 2017;7(0):43736.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Angiopoietin-1 Modified Human Umbilical Cord Mesenchymal Stem Cell Therapy for Endotoxin-Induced Acute Lung Injury in Rats
    Authors: Xiu Li Ju
    Yonsei Med. J., 2017;58(1):206-216.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  65. A randomized, single-blind, Phase I trial (INVICTAN-1) assessing the bioequivalence and safety of BI 695502, a bevacizumab biosimilar candidate, in healthy subjects
    Authors: W Hettema, C Wynne, B Lang, M Altendorfe, N Czeloth, R Lohmann, S Athalye, D Schliephak
    Expert Opin Investig Drugs, 2017;0(0):.
    Applications: ELISA (Capture)
  66. Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy
    Authors: ME LeBlanc, W Wang, X Chen, NB Caberoy, F Guo, C Shen, Y Ji, H Tian, H Wang, R Chen, W Li
    J. Exp. Med, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Hyaluronan-Binding Protein Involved in Hyaluronan Depolymerization Controls Endochondral Ossification through Hyaluronan Metabolism
    Authors: M Shimoda, H Yoshida, S Mizuno, T Hirozane, K Horiuchi, Y Yoshino, H Hara, Y Kanai, S Inoue, M Ishijima, Y Okada
    Am. J. Pathol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Matrix Stiffness Enhances VEGFR-2 Internalization, Signaling, and Proliferation in Endothelial Cells
    Authors: DJ LaValley, MR Zanotelli, F Bordeleau, W Wang, SC Schwager, CA Reinhart-K
    Converg Sci Phys Oncol, 2017;3(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Gelatin device for the delivery of growth factors involved in endochondral ossification
    Authors: LA Ahrens, D Vonwil, J Christense, VP Shastri
    PLoS ONE, 2017;12(4):e0175095.
    Species: Chicken
    Sample Types: Egg
    Applications: Bioassay
  70. Apatinib, an Inhibitor of Vascular Endothelial Growth Factor Receptor 2, Suppresses Pathologic Ocular Neovascularization in Mice
    Authors: KL Kim, W Suh
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3592-3599.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. MicroRNA-30b controls endothelial cell capillary morphogenesis through regulation of transforming growth factor beta 2
    Authors: GA Howe, K Kazda, CL Addison
    PLoS ONE, 2017;12(10):e0185619.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
    Authors: E Giacomelli, M Bellin, L Sala, BJ van Meer, LG Tertoolen, VV Orlova, CL Mummery
    Development, 2017;144(6):1008-1017.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Inhibition of Single Routes of Intracellular Signaling is Not Sufficient to Neutralize the Biphasic Disturbance of a Retinal Endothelial Cell Barrier Induced by VEGF-A165
    Authors: HL Deissler, GK Lang, GE Lang
    Cell. Physiol. Biochem., 2017;42(4):1493-1513.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Endothelial adenosine A2a receptor-mediated glycolysis is essential for pathological retinal angiogenesis
    Authors: Z Liu, S Yan, J Wang, Y Xu, Y Wang, S Zhang, X Xu, Q Yang, X Zeng, Y Zhou, X Gu, S Lu, Z Fu, DJ Fulton, NL Weintraub, RB Caldwell, W Zhang, C Wu, XL Liu, JF Chen, A Ahmad, I Kaddour-Dj, M Al-Shabraw, Q Li, X Jiang, Y Sun, A Sodhi, L Smith, M Hong, Y Huo
    Nat Commun, 2017;8(1):584.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis
    Authors: J Cao, M Ehling, S März, J Seebach, K Tarbashevi, T Sixta, ME Pitulescu, AC Werner, B Flach, E Montanez, E Raz, RH Adams, H Schnittler
    Nat Commun, 2017;8(1):2210.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Discovery of High-Affinity PDGF-VEGFR Interactions: Redefining RTK Dynamics
    Authors: SB Mamer, S Chen, JC Weddell, A Palasz, A Wittenkell, M Kumar, PI Imoukhuede
    Sci Rep, 2017;7(1):16439.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  77. Discovery of novel 2-substituted-4-(2-fluorophenoxy) pyridine derivatives possessing pyrazolone and triazole moieties as dual c-Met/VEGFR-2 receptor tyrosine kinase inhibitors
    Authors: W Gu, Y Dai, H Qiang, W Shi, C Liao, F Zhao, W Huang, H Qian
    Bioorg. Chem., 2017;72(0):116-122.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Ehmt2/G9a controls placental vascular maturation by activating the Notch pathway
    Authors: L Chi, A Ahmed, AR Roy, S Vuong, LS Cahill, L Caporiccio, JG Sled, I Caniggia, MD Wilson, P Delgado-Ol
    Development, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. TSLP promotes angiogenesis of human umbilical vein endothelial cells by strengthening the crosstalk between cervical cancer cells and eosinophils
    Authors: B Zhang, CY Wei, KK Chang, JJ Yu, WJ Zhou, HL Yang, J Shao, JJ Yu, MQ Li, F Xie
    Oncol Lett, 2017;14(6):7483-7488.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  80. TNFSF15 inhibits VEGF-stimulated vascular hyperpermeability by inducing VEGFR2 dephosphorylation
    Authors: GL Yang, Z Zhao, TT Qin, D Wang, L Chen, R Xiang, Z Xi, R Jiang, ZS Zhang, J Zhang, LY Li
    FASEB J, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  81. Efficacy of aflibercept (EYLEA(�)) on inhibition of human VEGF in vitro
    Authors: M Schicht, K Hesse, H Schröder, E Naschberge, W Lamprecht, F Garreis, FP Paulsen, L Bräuer
    Ann. Anat, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. In smokers, Sonic hedgehog modulates pulmonary endothelial function through vascular endothelial growth factor
    Authors: P Henno, S Grassin-De, E Belle, M Brollo, E Naline, E Sage, P Devillier, D Israël-Bie
    Respir. Res., 2017;18(1):102.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  83. Inhibition of VEGF-Induced VEGFR-2 Activation and HUVEC Migration by Melatonin and Other Bioactive Indolic Compounds
    Authors: AB Cerezo, R Hornedo-Or, MA Álvarez-Fe, AM Troncoso, MC García-Par
    Nutrients, 2017;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Establishment of a three-dimensional model to study human uterine angiogenesis
    Authors: CL Duran, CA Abbey, KJ Bayless
    Mol. Hum. Reprod., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. PM2.5 exposure decreases viability, migration and angiogenesis in human umbilical vein endothelial cells and human microvascular endothelial cells
    Authors: S Chen, X Wu, J Hu, G Dai, A Rong, G Guo
    Mol Med Rep, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations
    Authors: JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
    Cell Stem Cell, 2017;21(2):179-194.e4.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Antiangiogenic effect of dasatinib in murine models of oxygen-induced retinopathy and laser-induced choroidal neovascularization
    Authors: S Seo, W Suh
    Mol. Vis., 2017;23(0):823-831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
    Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
    Exp. Mol. Med., 2017;49(8):e363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Dual targeting of vascular endothelial growth factor and bone morphogenetic protein-9/10 impairs tumor growth through inhibition of angiogenesis
    Authors: Y Akatsu, Y Yoshimatsu, T Tomizawa, K Takahashi, A Katsura, K Miyazono, T Watabe
    Cancer Sci, 2017;108(1):151-155.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Exclusive inhibition of PI3K/Akt/mTOR signaling is not sufficient to prevent PDGF-mediated effects on glycolysis and proliferation in colorectal cancer
    Oncotarget, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Angiogenic Effects of Collagen/Mesoporous Nanoparticle Composite Scaffold Delivering VEGF165
    Biomed Res Int, 2016;2016(0):9676934.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  92. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance
    Authors: C Jang, SF Oh, S Wada, GC Rowe, L Liu, MC Chan, J Rhee, A Hoshino, B Kim, A Ibrahim, LG Baca, E Kim, CC Ghosh, SM Parikh, A Jiang, Q Chu, DE Forman, SH Lecker, S Krishnaiah, JD Rabinowitz, AM Weljie, JA Baur, DL Kasper, Z Arany
    Nat Med, 2016;22(4):421-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. A Quininib Analogue and Cysteinyl Leukotreine Receptor Antagonist inhibits VEGF-Independent Angiogenesis and Exerts an Additive Anti-angiogenic Response with Bevacizumab
    Authors: Clare T Butler
    J. Biol. Chem, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Mesenchymal Stem Cells Reshape and Provoke Proliferation of Articular Chondrocytes by Paracrine Secretion
    Sci Rep, 2016;6(0):32705.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  95. The Robo4 cytoplasmic domain is dispensable for vascular permeability and neovascularization
    Nat Commun, 2016;7(0):13517.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. CNTF Attenuates Vasoproliferative Changes Through Upregulation of SOCS3 in a Mouse-Model of Oxygen-Induced Retinopathy
    Invest Ophthalmol Vis Sci, 2016;57(10):4017-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Proangiogenic Interactions of Vascular Endothelial MMP14 With VEGF Receptor 1 in VEGFA-Mediated Corneal Angiogenesis.
    Authors: Kyu-Yeon Han, Jin-Hong Chang, Hyun Lee, Dimitri T Azar
    Investigative Ophthalmology & Visual Science, 2016;0(0):1552-5783.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  98. Deciphering the Role of Emx1 in Neurogenesis: A Neuroproteomics Approach
    Authors: Jialing Liu
    Front Mol Neurosci, 2016;9(0):98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function
    Authors: GJ Prud'homme, Y Glinka, Z Lichner, GM Yousef
    Oncotarget, 2016;7(42):68057-68071.
    Species: Human
    Sample Types: RNA
    Applications: Bioassay
  100. Miniaturizing VEGF: Peptides mimicking the discontinuous VEGF receptor-binding site modulate the angiogenic response
    Sci Rep, 2016;6(0):31295.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Ureteral reconstruction with reinforced collagen scaffolds in a porcine model
    Authors: Wout Feitz
    J Tissue Eng Regen Med, 2016;0(0):.
    Applications: Bioassay
  102. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016;6(0):39190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. The Poly-cistronic miR-23-27-24 Complexes Target Endothelial Cell Junctions: Differential Functional and Molecular Effects of miR-23a and miR-23b
    Authors: Jia Li
    Mol Ther Nucleic Acids, 2016;5(8):e354.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Intra-laboratory validated human cell-based in vitro vasculogenesis/angiogenesis test with serum-free medium
    Authors: T Toimela
    Reprod. Toxicol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Opposite Effects of Mechanical Action of Fluid Flow on Proangiogenic Factor Secretion from Human Adipose-Derived Stem Cells with and without Oxidative Stress
    Authors: Beatriz Bravo
    J. Cell. Physiol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Analysis of angiogenesis related factors in glioblastoma, peritumoral tissue and their derived cancer stem cells.
    Authors: Alessio D'alessio, Gabriella Proietti, Gina Lama, Filippo Biamonte, Libero Lauriola, Umberto Moscato, Angelo Vescovi, Annunziato Mangiola, Cristiana Angelucci, Gigliola Sica
    Oncotarget, 2016;0(0):1949-2553.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation
    Authors: I Papangeli, J Kim, I Maier, S Park, A Lee, Y Kang, K Tanaka, OF Khan, H Ju, Y Kojima, K Red-Horse, DG Anderson, AF Siekmann, HJ Chun
    Nat Commun, 2016;7(0):11268.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Tie1 controls angiopoietin function in vascular remodeling and inflammation
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Proline-rich tyrosine kinase 2 via enhancing signal transducer and activator of transcription 3-dependent cJun expression mediates retinal neovascularization
    Sci Rep, 2016;6(0):26480.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Automated image analysis with the potential for process quality control applications in stem cell maintenance and differentiation
    Authors: Robert Thomas
    Biotechnol. Prog., 2016;32(1):215-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain
    Neurobiol Dis, 2016;96(0):186-200.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  112. Soluble VEGF receptor 1 (sFLT1) induces non-apoptotic death in ovarian and colorectal cancer cells.
    Authors: Tatsuya Miyake, Keiichi Kumasawa, Noriko Sato, Tsuyoshi Takiuchi, Hitomi Nakamura, Tadashi Kimura
    Scientific Reports, 2016;0(0):2045-2322.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. VEGF drives cancer-initiating stem cells through VEGFR-2/Stat3 signaling to upregulate Myc and Sox2.
    Authors: Zhao D, Pan C, Sun J, Gilbert C, Drews-Elger K, Azzam D, Picon-Ruiz M, Kim M, Ullmer W, El-Ashry D, Creighton C, Slingerland J
    Oncogene, 2015;34(24):3107-19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth.
    Authors: Wang T, Xiao M, Ge Y, Krepler C, Belser E, Lopez-Coral A, Xu X, Zhang G, Azuma R, Liu Q, Liu R, Li L, Amaravadi R, Xu W, Karakousis G, Gangadhar T, Schuchter L, Lieu M, Khare S, Halloran M, Herlyn M, Kaufman R
    Clin Cancer Res, 2015;21(7):1652-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development.
    Authors: Schaker K, Bartsch S, Patry C, Stoll S, Hillebrands J, Wieland T, Kroll J
    J Biol Chem, 2015;290(10):6408-18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. The proangiogenic effect of iroquois homeobox transcription factor Irx3 in human microvascular endothelial cells.
    Authors: Scarlett K, Pattabiraman V, Barnett P, Liu D, Anderson L
    J Biol Chem, 2015;290(10):6303-15.
  117. Hypoxia augments outgrowth endothelial cell (OEC) sprouting and directed migration in response to sphingosine-1-phosphate (S1P).
    Authors: Williams P, Stilhano R, To V, Tran L, Wong K, Silva E
    PLoS ONE, 2015;10(4):e0123437.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. The effect of vascular endothelial growth factor on osteoclastogenesis in rheumatoid arthritis.
    Authors: Kim H, Kim K, Kim B, Cho M, Lee S
    PLoS ONE, 2015;10(4):e0124909.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Inhibition of IGF-1-Mediated Cellular Migration and Invasion by Migracin A in Ovarian Clear Cell Carcinoma Cells.
    Authors: Ukaji T, Lin Y, Banno K, Okada S, Umezawa K
    PLoS ONE, 2015;10(9):e0137663.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. JSI-124 suppresses invasion and angiogenesis of glioblastoma cells in vitro.
    Authors: Yuan G, Yan S, Xue H, Zhang P, Sun J, Li G
    PLoS ONE, 2015;10(3):e0118894.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization.
    Authors: Rama N, Dubrac A, Mathivet T, Ni Charthaigh R, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chedotal A
    Nat Med, 2015;21(5):483-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
    Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
    Nat Commun, 2015;6(0):6576.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. IL-25 induces airways angiogenesis and expression of multiple angiogenic factors in a murine asthma model.
    Authors: Yao, Xiujuan, Wang, Wei, Li, Yan, Huang, Ping, Zhang, Qian, Wang, Jingjing, Wang, Wen, Lv, Zhe, An, Yunqing, Qin, Jianguo, Corrigan, Chris J, Huang, Kewu, Sun, Yongchan, Ying, Sun
    Respir Res, 2015;16(0):39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Synergistic Binding of Vascular Endothelial Growth Factor-A and Its Receptors to Heparin Selectively Modulates Complex Affinity.
    Authors: Teran M, Nugent M
    J Biol Chem, 2015;290(26):16451-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Ecto-5'-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature.
    Authors: Yegutkin G, Auvinen K, Rantakari P, Hollmen M, Karikoski M, Grenman R, Elima K, Jalkanen S, Salmi M
    Eur J Immunol, 2015;45(2):562-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Improved hematopoietic differentiation efficiency of gene-corrected beta-thalassemia induced pluripotent stem cells by CRISPR/Cas9 system.
    Authors: Song B, Fan Y, He W, Zhu D, Niu X, Wang D, Ou Z, Luo M, Sun X
    Stem Cells Dev, 2015;24(9):1053-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Insulin-like growth factor 1 (IGF-1) stabilizes nascent blood vessels.
    Authors: Jacobo S, Kazlauskas A
    J Biol Chem, 2015;290(10):6349-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. R-Ras protein inhibits autophosphorylation of vascular endothelial growth factor receptor 2 in endothelial cells and suppresses receptor activation in tumor vasculature.
    Authors: Sawada J, Li F, Komatsu M
    J Biol Chem, 2015;290(13):8133-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. GSK3beta inhibition activates the CDX/HOX pathway and promotes hemogenic endothelial progenitor differentiation from human pluripotent stem cells.
    Authors: Kitajima K, Nakajima M, Kanokoda M, Kyba M, Dandapat A, Tolar J, Saito M, Toyoda M, Umezawa A, Hara T
    Exp Hematol, 2015;44(1):68-74.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development.
    Authors: Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y
    PLoS ONE, 2014;9(4):e94239.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Memo has a novel role in S1P signaling and is [corrected] crucial for vascular development.
    Authors: Kondo, Shunya, Bottos, Alessia, Allegood, Jeremy C, Masson, Regis, Maurer, Francisc, Genoud, Christel, Kaeser, Patrick, Huwiler, Andrea, Murakami, Masato, Spiegel, Sarah, Hynes, Nancy E
    PLoS ONE, 2014;9(4):e94114.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Antifibrotic and anti-inflammatory activity of the tyrosine kinase inhibitor nintedanib in experimental models of lung fibrosis.
    Authors: Wollin L, Maillet I, Quesniaux V, Holweg A, Ryffel B
    J Pharmacol Exp Ther, 2014;349(2):209-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014;32(10):2714-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. LF-15 & T7, synthetic peptides derived from tumstatin, attenuate aspects of airway remodelling in a murine model of chronic OVA-induced allergic airway disease.
    Authors: Grafton K, Moir L, Black J, Hansbro N, Hansbro P, Burgess J, Oliver B
    PLoS ONE, 2014;9(1):e85655.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses.
    Authors: Ashino S, Takeda K, Li H, Taylor V, Joetham A, Pine P, Gelfand E
    J Allergy Clin Immunol, 2014;133(4):1162-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Sox7 is regulated by ETV2 during cardiovascular development.
    Authors: Behrens, Ann N, Zierold, Claudia, Shi, Xiaozhon, Ren, Yi, Koyano-Nakagawa, Naoko, Garry, Daniel J, Martin, Cindy M
    Stem Cells Dev, 2014;23(17):2004-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. An in vitro cord formation assay identifies unique vascular phenotypes associated with angiogenic growth factors.
    Authors: Falcon B, Swearingen M, Gough W, Lee L, Foreman R, Uhlik M, Hanson J, Lee J, McClure D, Chintharlapalli S
    PLoS ONE, 2014;9(9):e106901.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling.
    Authors: Fan J, Ponferrada V, Sato T, Vemaraju S, Fruttiger M, Gerhardt H, Ferrara N, Lang R
    Development, 2014;141(2):448-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. The docking protein FRS2alpha is a critical regulator of VEGF receptors signaling.
    Authors: Chen P, Qin L, Zhuang Z, Tellides G, Lax I, Schlessinger J, Simons M
    Proc Natl Acad Sci U S A, 2014;111(15):5514-9.
  140. Intraocular pharmacokinetics of ranibizumab in vitrectomized versus nonvitrectomized eyes.
    Authors: Ahn S, Ahn J, Park S, Kim H, Hwang D, Park J, Park J, Chung J, Park K, Woo S
    Invest Ophthalmol Vis Sci, 2014;55(1):567-73.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  141. PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells.
    Authors: Lanahan A, Lech D, Dubrac A, Zhang J, Zhuang Z, Eichmann A, Simons M
    Circulation, 2014;130(11):902-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  142. Peroxisome proliferator-activated receptor gamma ligands inhibit VEGF-mediated vasculogenic mimicry of prostate cancer through the AKT signaling pathway.
    Authors: Qin L, Ren Y, Chen A, Guo F, Xu F, Gong C, Cheng P, Du Y, Liao H
    Mol Med Rep, 2014;10(1):276-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Effects of sFlt-1 and alpha 2-macroglobulin on vascular endothelial growth factor-induced endothelin-1 upregulation in human microvascular endothelial cells.
    Authors: Yi K, Jung S, Cho G, Seol H, Hong S, Oh M, Kim H
    Placenta, 2014;35(1):64-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Conformational remodeling of the fibronectin matrix selectively regulates VEGF signaling.
    Authors: Ambesi A, McKeown-Longo P
    J Cell Sci, 2014;127(0):3805-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Functionality of endothelial cells and pericytes from human pluripotent stem cells demonstrated in cultured vascular plexus and zebrafish xenografts.
    Authors: Orlova, Valeria, Drabsch, Yvette, Freund, Christia, Petrus-Reurer, Sandra, van den Hil, Francijn, Muenthaisong, Suchitra, Dijke, Peter Te, Mummery, Christin
    Arterioscler Thromb Vasc Biol, 2014;34(1):177-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment.
    Authors: Adini, Irit, Ghosh, Kaustabh, Adini, Avner, Chi, Zai-Long, Yoshimura, Takeru, Benny, Ofra, Connor, Kip M, Rogers, Michael, Bazinet, Lauren, Birsner, Amy E, Bielenberg, Diane R, D'Amato, Robert J
    J Clin Invest, 2014;124(1):425-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  147. Rap1b in smooth muscle and endothelium is required for maintenance of vascular tone and normal blood pressure.
    Authors: Lakshmikanthan S, Zieba B, Ge Z, Momotani K, Zheng X, Lund H, Artamonov M, Maas J, Szabo A, Zhang D, Auchampach J, Mattson D, Somlyo A, Chrzanowska-Wodnicka M
    Arterioscler Thromb Vasc Biol, 2014;34(7):1486-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Genetic correction of HAX1 in induced pluripotent stem cells from a patient with severe congenital neutropenia improves defective granulopoiesis.
    Authors: Morishima, Tatsuya, Watanabe, Ken-ichi, Niwa, Akira, Hirai, Hideyo, Saida, Satoshi, Tanaka, Takayuki, Kato, Itaru, Umeda, Katsutsu, Hiramatsu, Hidefumi, Saito, Megumu K, Matsubara, Kousaku, Adachi, Souichi, Kobayashi, Masao, Nakahata, Tatsutos, Heike, Toshio
    Haematologica, 2014;99(1):19-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Dll4-containing exosomes induce capillary sprout retraction in a 3D microenvironment.
    Authors: Sharghi-Namini S, Tan E, Ong L, Ge R, Asada H
    Sci Rep, 2014;4(0):4031.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling.
    Authors: Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, Moser C, Shaleh H, Thornburgh S, Walters I, Roberts L
    PLoS ONE, 2014;9(4):e92273.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. MMP9 processing of HSPB1 regulates tumor progression.
    Authors: Choi, Seo-hyun, Lee, Hae-June, Jin, Yeung Ba, Jang, Junho, Kang, Ga-young, Lee, Minyoung, Kim, Chun-Ho, Kim, Joon, Yoon, Sam S, Lee, Yun-sil, Lee, Yoon-Jin
    PLoS ONE, 2014;9(1):e85509.
  152. Gas6 stimulates angiogenesis of human retinal endothelial cells and of zebrafish embryos via ERK1/2 signaling.
    Authors: Kim, Young So, Jung, Seung-Hy, Jung, Dong Ho, Choi, So-Jin, Lee, Yu-Ri, Kim, Jin Sook
    PLoS ONE, 2014;9(1):e83901.
    Species: Zebrafish
    Sample Types: Whole Organism
    Applications: In Vivo
  153. Granzyme B releases vascular endothelial growth factor from extracellular matrix and induces vascular permeability.
    Authors: Hendel, Alon, Hsu, Ivy, Granville, David J
    Lab Invest, 2014;94(7):716-25.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  154. Simultaneous targeting of two ligand-binding sites on VEGFR2 using biparatopic Affibody molecules results in dramatically improved affinity.
    Authors: Fleetwood F, Klint S, Hanze M, Gunneriusson E, Frejd F, Stahl S, Lofblom J
    Sci Rep, 2014;4(0):7518.
  155. Glutathione adducts on sarcoplasmic/endoplasmic reticulum Ca2+ ATPase Cys-674 regulate endothelial cell calcium stores and angiogenic function as well as promote ischemic blood flow recovery.
    Authors: Thompson M, Mei Y, Weisbrod R, Silver M, Shukla P, Bolotina V, Cohen R, Tong X
    J Biol Chem, 2014;289(29):19907-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Heparin binding VEGF isoforms attenuate hyperoxic embryonic lung growth retardation via a FLK1-neuropilin-1-PKC dependent pathway.
    Authors: Esquibies A, Karihaloo A, Quaggin S, Bazzy-Asaad A, Cantley L
    Respir Res, 2014;15(0):32.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  157. Generation, expansion and functional analysis of endothelial cells and pericytes derived from human pluripotent stem cells.
    Authors: Orlova, Valeria, van den Hil, Francijn, Petrus-Reurer, Sandra, Drabsch, Yvette, Ten Dijke, Peter, Mummery, Christin
    Nat Protoc, 2014;9(6):1514-31.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Endothelial podosome rosettes regulate vascular branching in tumour angiogenesis.
    Authors: Seano G, Chiaverina G, Gagliardi P, di Blasio L, Puliafito A, Bouvard C, Sessa R, Tarone G, Sorokin L, Helley D, Jain R, Serini G, Bussolino F, Primo L
    Nat Cell Biol, 2014;16(10):931-41, 1-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  159. Angiogenic sprouting is regulated by endothelial cell expression of Slug.
    Authors: Welch-Reardon K, Ehsan S, Wang K, Wu N, Newman A, Romero-Lopez M, Fong A, George S, Edwards R, Hughes C
    J Cell Sci, 2014;127(0):2017-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. miR-27a regulates endothelial differentiation of breast cancer stem like cells.
    Authors: Tang, W, Yu, F, Yao, H, Cui, X, Jiao, Y, Lin, L, Chen, J, Yin, D, Song, E, Liu, Q
    Oncogene, 2014;33(20):2629-38.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas.
    Authors: Shahrabi-Farahani, Shokoufe, Wang, Lili, Zwaans, Bernadet, Santana, Jeans M, Shimizu, Akio, Takashima, Seiji, Kreuter, Michael, Coultas, Leigh, D'Amore, Patricia, Arbeit, Jeffrey, Akslen, Lars A, Bielenberg, Diane R
    Lab Invest, 2014;94(7):752-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye.
    Authors: Michael, Iacovos, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa C, Ballios, Brian G, Kurihara, Toshihid, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentin, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
    EMBO Mol Med, 2014;6(5):604-23.
  163. Resveratrol attenuates diabetic nephropathy via modulating angiogenesis.
    Authors: Wen, Donghai, Huang, Xinzhong, Zhang, Min, Zhang, Liying, Chen, Jing, Gu, Yong, Hao, Chuan-Mi
    PLoS ONE, 2013;8(12):e82336.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Unraveling a novel transcription factor code determining the human arterial-specific endothelial cell signature.
    Authors: Aranguren X, Agirre X, Beerens M, Coppiello G, Uriz M, Vandersmissen I, Benkheil M, Panadero J, Aguado N, Pascual-Montano A, Segura V, Prosper F, Luttun A
    Blood, 2013;122(24):3982-92.
    Species: Human
    Sample Types: In Vivo
    Applications: In Vivo
  165. Structure-activity relationships of benzbromarone metabolites and derivatives as EYA inhibitory anti-angiogenic agents.
    Authors: Pandey, Ram Nare, Wang, Tim Sen, Tadjuidje, Emmanuel, McDonald, Matthew, Rettie, Allan E, Hegde, Rashmi S
    PLoS ONE, 2013;8(12):e84582.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  166. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis.
    Authors: Zhang G, Panigrahy D, Mahakian L, Yang J, Liu J, Stephen Lee K, Wettersten H, Ulu A, Hu X, Tam S, Hwang S, Ingham E, Kieran M, Weiss R, Ferrara K, Hammock B
    Proc Natl Acad Sci U S A, 2013;110(16):6530-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Distinct transcriptional profiles of angioblasts derived from human embryonic stem cells.
    Authors: Song S, Jung W, Kim K, Hong W, Kim H, Lee K, Lee K, Suh W
    Exp Cell Res, 2013;319(8):1136-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Simple patterned nanofiber scaffolds and its enhanced performance in immunoassay.
    Authors: Wang, Jing, Kang, Qin-shu, Lv, Xiao-gua, Song, Jia, Zhan, Na, Dong, Wei-guo, Huang, Wei-hua
    PLoS ONE, 2013;8(12):e82888.
    Species: Human
    Sample Types: N/A
    Applications: Immunoassay Development
  169. Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.
    Authors: Su, Yu-Ting, Gao, Chengzhu, Liu, Yu, Guo, Shuang, Wang, Anthony, Wang, Benlian, Erdjument-Bromage, Hediye, Miyagi, Masaru, Tempst, Paul, Kao, Hung-Yin
    Mol Cell Biol, 2013;33(8):1546-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Loss of CCM3 impairs DLL4-Notch signalling: implication in endothelial angiogenesis and in inherited cerebral cavernous malformations.
    Authors: You C, Sandalcioglu I, Dammann P, Felbor U, Sure U, Zhu Y
    J Cell Mol Med, 2013;17(3):407-18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglin.
    Authors: Tannetta D, Dragovic R, Gardiner C, Redman C, Sargent I
    PLoS ONE, 2013;8(2):e56754.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Abl family kinases regulate endothelial barrier function in vitro and in mice.
    Authors: Chislock, Elizabet, Pendergast, Ann Mari
    PLoS ONE, 2013;8(12):e85231.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Detection of rapalog-mediated therapeutic response in renal cancer xenografts using (6)(4)Cu-bevacizumab immunoPET.
    Authors: Chang A, Sohn R, Lu Z, Arbeit J, Lapi S
    PLoS ONE, 2013;8(0):U821.
    Species: Human
    Sample Types: Antibody
    Applications: Bioassay
  174. Detection of VEGF-A(xxx)b isoforms in human tissues.
    Authors: Bates, David O, Mavrou, Athina, Qiu, Yan, Carter, James G, Hamdollah-Zadeh, Maryam, Barratt, Shaney, Gammons, Melissa, Millar, Ann B, Salmon, Andrew H, Oltean, Sebastia, Harper, Steven J
    PLoS ONE, 2013;8(7):e68399.
    Species: N/A
    Sample Types: Recombinant Protein
    Applications: Western Blot
  175. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions.
    Authors: Smith A, Bowers S, Stratman A, Davis G
    PLoS ONE, 2013;8(12):e85147.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. HOXC9 regulates formation of parachordal lymphangioplasts and the thoracic duct in zebrafish via stabilin 2.
    Authors: Stoll S, Bartsch S, Kroll J
    PLoS ONE, 2013;8(3):e58311.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Overexpression of the autoimmunity-associated phosphatase PTPN22 promotes survival of antigen-stimulated CLL cells by selectively activating AKT.
    Blood, 2012;119(26):6278-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting.
    Authors: van Meeteren LA, Thorikay M, Bergqvist S, Pardali E, Stampino CG, Hu-Lowe D, Goumans MJ, ten Dijke P
    J. Biol. Chem., 2012;287(22):18551-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. The regulatory roles of apoptosis-inducing factor in the formation and regression processes of ocular neovascularization.
    Authors: Hisatomi T, Nakao S, Murakami Y, Noda K, Nakazawa T, Notomi S, Connolly E, She H, Almulki L, Ito Y, Vavvas DG, Ishibashi T, Miller JW
    Am. J. Pathol., 2012;181(1):53-61.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  180. Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/integrin alphavbeta5-induced secretion of VEGF-A.
    Am. J. Pathol., 2012;181(2):693-705.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Sjogren's syndrome pathological neovascularization is regulated by VEGF-A-stimulated TACE-dependent crosstalk between VEGFR2 and NF-kappaB.
    Authors: Sisto M, Lisi S, Lofrumento DD, D'Amore M, Frassanito MA, Ribatti D
    Genes Immun., 2012;13(5):411-20.
    Species: Chicken
    Sample Types: In Ovo
    Applications: Bioassay
  182. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma.
    Authors: Dupuy S, Lambert M, Zucman D, Choukem SP, Tognarelli S, Pages C, Lebbe C, Caillat-Zucman S
    PLoS Pathog., 2012;8(1):e1002486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. ADAMTS5 functions as an anti-angiogenic and anti-tumorigenic protein independent of its proteoglycanase activity.
    Authors: Kumar S, Sharghi-Namini S, Rao N, Ge R
    Am J Pathol, 2012;181(3):1056-68.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
    Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
    Blood, 2012;120(19):4104-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Flt-1 regulates vascular endothelial cell migration via a protein tyrosine kinase-7-dependent pathway.
    Authors: Lee HK, Chauhan SK, Kay E
    Blood, 2011;117(21):5762-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. A novel serum-free monolayer culture for orderly hematopoietic differentiation of human pluripotent cells via mesodermal progenitors.
    Authors: Niwa A, Heike T, Umeda K
    PLoS ONE, 2011;6(7):e22261.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8.
    Authors: Delgado VM, Nugnes LG, Colombo LL, Troncoso MF, Fernandez MM, Malchiodi EL, Frahm I, Croci DO, Compagno D, Rabinovich GA, Wolfenstein-Todel C, Elola MT
    FASEB J., 2011;25(1):242-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation.
    Authors: Pirotte S, Lamour V, Lambert V, Alvarez Gonzalez ML, Ormenese S, Noel A, Mottet D, Castronovo V, Bellahcene A
    Blood, 2011;117(8):2515-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Increased VEGFR-2 Gene Copy Is Associated with Chemoresistance and Shorter Survival in Patients with Non-Small-Cell Lung Carcinoma Who Receive Adjuvant Chemotherapy.
    Authors: Yang F, Tang X, Riquelme E, Behrens C, Nilsson MB, Giri U, Varella-Garcia M, Byers LA, Lin HY, Wang J, Raso MG, Girard L, Coombes K, Lee JJ, Herbst RS, Minna JD, Heymach JV, Wistuba II
    Cancer Res., 2011;71(16):5512-5521.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Endorepellin, the angiostatic module of perlecan, interacts with both the alpha2beta1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism.
    Authors: Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV
    J. Biol. Chem., 2011;286(29):25947-62.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Binding Assay
  191. Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells.
    Authors: Evans IM, Yamaji M, Britton G, Pellet-Many C, Lockie C, Zachary IC, Frankel P
    Mol. Cell. Biol., 2011;31(6):1174-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state.
    Authors: Lanner F, Lee KL, Sohl M, Holmborn K, Yang H, Wilbertz J, Poellinger L, Rossant J, Farnebo F
    Stem Cells, 2010;28(2):191-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma.
    Authors: Cocco C, Giuliani N, Di Carlo E
    Clin. Cancer Res., 2010;16(16):4188-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Vascular endothelial growth factor is crucial for erythropoietin-induced improvement of cardiac function in heart failure.
    Authors: Westenbrink BD, Ruifrok WP, Voors AA
    Cardiovasc. Res., 2010;87(1):30-9.
    Species: Rat
    Sample Types: Plasma
    Applications: Bioassay
  195. Neuropilin-1 regulates platelet-derived growth factor receptor signalling in mesenchymal stem cells.
    Authors: Ball SG, Bayley C, Shuttleworth CA, Kielty CM
    Biochem. J., 2010;427(1):29-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Vitreous VEGF clearance is increased after vitrectomy.
    Authors: Lee SS, Ghosn C, Yu Z, Zacharias LC, Kao H, Lanni C, Abdelfattah N, Kuppermann B, Csaky KG, D'Argenio DZ, Burke JA, Hughes PM, Robinson MR
    Invest. Ophthalmol. Vis. Sci., 2010;51(4):2135-8.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  197. Lymphangiogenesis and angiogenesis: concurrence and/or dependence? Studies in inbred mouse strains.
    Authors: Nakao S, Maruyama K, Zandi S, Melhorn MI, Taher M, Noda K, Nusayr E, Doetschman T, Hafezi-Moghadam A
    FASEB J., 2010;24(2):504-13.
  198. Platelet-derived growth factor (PDGF)-PDGF receptor interaction activates bone marrow-derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch.
    Authors: Ding W, Knox TR, Tschumper RC
    Blood, 2010;116(16):2984-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Macrophage inhibitory cytokine-1 regulates melanoma vascular development.
    Authors: Huh SJ, Chung CY, Sharma A
    Am. J. Pathol., 2010;176(6):2948-57.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  200. Angiopoietin-4 promotes glioblastoma progression by enhancing tumor cell viability and angiogenesis.
    Authors: Brunckhorst MK, Wang H, Lu R, Yu Q
    Cancer Res., 2010;70(18):7283-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain.
    Authors: Martino MM, Hubbell JA
    FASEB J., 2010;24(12):4711-21.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  202. Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis.
    Authors: Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G
    Blood, 2010;116(16):3099-107.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7.
    Authors: Jung DW, Che ZM, Kim J, Kim K, Kim KY, Williams D, Kim J
    Int. J. Cancer, 2010;127(2):332-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Vascular endothelial growth factor drives autocrine epithelial cell proliferation and survival in chronic rhinosinusitis with nasal polyposis.
    Authors: Lee HS, Myers A, Kim J
    Am. J. Respir. Crit. Care Med., 2009;180(11):1056-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. The hypoxia-inducible factor 1/NOR-1 axis regulates the survival response of endothelial cells to hypoxia.
    Authors: Martorell L, Gentile M, Rius J, Rodriguez C, Crespo J, Badimon L, Martinez-Gonzalez J
    Mol. Cell. Biol., 2009;29(21):5828-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. VEGF(121)b, a new member of the VEGF(xxx)b family of VEGF-A splice isoforms, inhibits neovascularisation and tumour growth in vivo.
    Authors: Rennel ES, Varey AH, Churchill AJ, Wheatley ER, Stewart L, Mather S, Bates DO, Harper SJ
    Br. J. Cancer, 2009;101(7):1183-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Production of scFv antibody fragments from a hybridoma with functional activity against human vascular endothelial growth factor.
    Authors: Irani Y, Brereton HM, Tilton RG
    Hybridoma (Larchmt), 2009;28(3):205-9.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Binding Assay
  209. Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells.
    Authors: Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, Daida H, Yano K, Ohhashi T, Oettgen P, Aird WC, Kodama T, Minami T
    J. Biol. Chem., 2009;284(42):29109-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/AP-1 pathway.
    Authors: Chien MH, Ku CC, Johansson G, Chen MW, Hsiao M, Su JL, Inoue H, Hua KT, Wei LH, Kuo ML
    Carcinogenesis, 2009;30(12):2005-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Identification of protein kinase D2 as a pivotal regulator of endothelial cell proliferation, migration, and angiogenesis.
    Authors: Hao Q, Wang L, Zhao ZJ, Tang H
    J. Biol. Chem., 2009;284(2):799-806.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Colocalization of the VEGF-R2 and the common IL-3/GM-CSF receptor beta chain to lipid rafts leads to enhanced p38 activation.
    Authors: Saulle E, Riccioni R, Coppola S, Parolini I, Diverio D, Riti V, Mariani G, Laufer S, Sargiacomo M, Testa U
    Br. J. Haematol., 2009;145(3):399-411.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Pleiotrophin produced by multiple myeloma induces transdifferentiation of monocytes into vascular endothelial cells: a novel mechanism of tumor-induced vasculogenesis.
    Authors: Chen H, Campbell RA, Chang Y, Li M, Wang CS, Li J, Sanchez E, Share M, Steinberg J, Berenson A, Shalitin D, Zeng Z, Gui D, Perez-Pinera P, Berenson RJ, Said J, Bonavida B, Deuel TF, Berenson JR
    Blood, 2009;113(9):1992-2002.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases.
    Authors: Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(24):9826-30.
  215. Expression of soluble vascular endothelial growth factor receptor-1 in human monocyte-derived mature dendritic cells contributes to their antiangiogenic property.
    Authors: Kishuku M, Nishioka Y, Abe S, Kishi J, Ogino H, Aono Y, Azuma M, Kinoshita K, Batmunkh R, Rentsenhand B, Makino H, Ranjan P, Minakuchi K, Sone S
    J. Immunol., 2009;183(12):8176-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. DC-SIGN mediates cell-free infection and transmission of human T-cell lymphotropic virus type 1 by dendritic cells.
    Authors: Jain P, Manuel SL, Khan ZK, Ahuja J, Quann K, Wigdahl B
    J. Virol., 2009;83(21):10908-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis.
    Authors: Gooz P, Gooz M, Baldys A, Hoffman S
    Biochem. Biophys. Res. Commun., 2009;380(1):33-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Hyperoxia disrupts vascular endothelial growth factor-nitric oxide signaling and decreases growth of endothelial colony-forming cells from preterm infants.
    Authors: Fujinaga H, Baker CD, Ryan SL, Markham NE, Seedorf GJ, Balasubramaniam V, Abman SH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(6):L1160-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Sensitive and multiplexed detection of proteomic antigens via quantum dot aggregation.
    Authors: Soman C, Giorgio T,
    Nanomedicine, 2009;5(4):402-9.
    Species: N/A
    Sample Types: N/A
    Applications: Quantum Dot
  220. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
    Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
    J. Clin. Invest., 2009;119(8):2257-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. The impact of proliferative potential of umbilical cord-derived endothelial progenitor cells and hypoxia on vascular tubule formation in vitro.
    Authors: Zhang Y, Fisher N, Newey SE
    Stem Cells Dev., 2009;18(2):359-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Angioinhibitory action of NK4 involves impaired extracellular assembly of fibronectin mediated by perlecan-NK4 association.
    Authors: Sakai K, Nakamura T, Matsumoto K, Nakamura T
    J. Biol. Chem., 2009;284(33):22491-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Vascular endothelial growth factor-mediated decrease in plasma soluble vascular endothelial growth factor receptor-2 levels as a surrogate biomarker for tumor growth.
    Authors: Ebos JM, Lee CR, Bogdanovic E, Alami J, Van Slyke P, Francia G, Xu P, Mutsaers AJ, Dumont DJ, Kerbel RS
    Cancer Res., 2008;68(2):521-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population.
    Authors: Yang L, Soonpaa MH, Adler ED, Roepke TK, Kattman SJ, Kennedy M, Henckaerts E, Bonham K, Abbott GW, Linden RM, Field LJ, Keller GM
    Nature, 2008;453(7194):524-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Development of anti-atherosclerotic tissue-engineered blood vessel by A20-regulated endothelial progenitor cells seeding decellularized vascular matrix.
    Authors: Zhu C, Ying D, Mi J, Li L, Zeng W, Hou C, Sun J, Yuan W, Wen C, Zhang W
    Biomaterials, 2008;29(17):2628-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression.
    Authors: Wanami LS, Chen HY, Peiro S, Garcia de Herreros A, Bachelder RE
    Exp. Cell Res., 2008;314(13):2448-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Sulfated polysaccharides identified as inducers of neuropilin-1 internalization and functional inhibition of VEGF165 and semaphorin3A.
    Authors: Narazaki M, Segarra M, Tosato G
    Blood, 2008;111(8):4126-36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Modulation of angiogenesis by a tetrameric tripeptide that antagonizes vascular endothelial growth factor receptor 1.
    Authors: Ponticelli S, Marasco D, Tarallo V, Albuquerque RJ, Mitola S, Takeda A, Stassen JM, Presta M, Ambati J, Ruvo M, De Falco S
    J. Biol. Chem., 2008;283(49):34250-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B.
    Authors: Lejmi E, Leconte L, Pedron-Mazoyer S, Ropert S, Raoul W, Lavalette S, Bouras I, Feron JG, Maitre-Boube M, Assayag F, Feumi C, Alemany M, Jie TX, Merkulova T, Poupon MF, Ruchoux MM, Tobelem G, Sennlaub F, Plouet J
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(34):12491-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Bone marrow cells recruited through the neuropilin-1 receptor promote arterial formation at the sites of adult neoangiogenesis in mice.
    Authors: Zacchigna S, Pattarini L, Zentilin L, Moimas S, Carrer A, Sinigaglia M, Arsic N, Tafuro S, Sinagra G, Giacca M
    J. Clin. Invest., 2008;118(6):2062-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Robo4 stabilizes the vascular network by inhibiting pathologic angiogenesis and endothelial hyperpermeability.
    Authors: Jones CA, London NR, Chen H, Park KW, Sauvaget D, Stockton RA, Wythe JD, Suh W, Larrieu-Lahargue F, Mukouyama YS, Lindblom P, Seth P, Frias A, Nishiya N, Ginsberg MH, Gerhardt H, Zhang K, Li DY
    Nat. Med., 2008;14(4):448-53.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  232. Plasma levels of soluble Tie2 and vascular endothelial growth factor distinguish critical limb ischemia from intermittent claudication in patients with peripheral arterial disease.
    Authors: Findley CM, Mitchell RG, Duscha BD, Annex BH, Kontos CD
    J. Am. Coll. Cardiol., 2008;52(5):387-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Transcriptional profiling of VEGF-A and VEGF-C target genes in lymphatic endothelium reveals endothelial-specific molecule-1 as a novel mediator of lymphangiogenesis.
    Authors: Shin JW, Huggenberger R, Detmar M
    Blood, 2008;112(6):2318-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis.
    Authors: Clerin V, Shih HH, Deng N, Hebert G, Resmini C, Shields KM, Feldman JL, Winkler A, Albert L, Maganti V, Wong A, Paulsen JE, Keith JC, Vlasuk GP, Pittman DD
    Atherosclerosis, 2008;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Dopamine regulates endothelial progenitor cell mobilization from mouse bone marrow in tumor vascularization.
    Authors: Chakroborty D, Chowdhury UR, Sarkar C, Baral R, Dasgupta PS, Basu S
    J. Clin. Invest., 2008;118(4):1380-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy.
    Authors: Hilberg F, Roth GJ, Krssak M, Kautschitsch S, Sommergruber W, Tontsch-Grunt U, Garin-Chesa P, Bader G, Zoephel A, Quant J, Heckel A, Rettig WJ
    Cancer Res., 2008;68(12):4774-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008;7(6):2406-14.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  238. Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation.
    Authors: Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH
    Diabetes, 2007;57(1):158-66.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  239. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques.
    Authors: Babinska A, Azari BM, Salifu MO, Liu R, Jiang XC, Sobocka MB, Boo D, Al Khoury G, Deitch JS, Marmur JD, Ehrlich YH, Kornecki E
    Thromb. Haemost., 2007;97(2):272-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Glomerular endothelial glycocalyx constitutes a barrier to protein permeability.
    Authors: Singh A, Satchell SC, Neal CR
    J. Am. Soc. Nephrol., 2007;18(11):2885-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Mutant anthrax toxin B moiety (protective antigen) inhibits angiogenesis and tumor growth.
    Authors: Rogers MS, Christensen KA, Birsner AE, Short SM, Wigelsworth DJ, Collier RJ, D'Amato RJ
    Cancer Res., 2007;67(20):9980-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Inhibition of hypoxia-induced increase of blood-brain barrier permeability by YC-1 through the antagonism of HIF-1alpha accumulation and VEGF expression.
    Authors: Yeh WL, Lu DY, Lin CJ, Liou HC, Fu WM
    Mol. Pharmacol., 2007;72(2):440-9.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells.
    Authors: Rajesh&lt;/LastName&gt;&lt;ForeNam D&lt;/Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF
    Stem Cells, 2007;25(2):490-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Lymphatic reprogramming of microvascular endothelial cells by CEA-related cell adhesion molecule-1 via interaction with VEGFR-3 and Prox1.
    Authors: Kilic N, Oliveira-Ferrer L, Neshat-Vahid S, Irmak S, Obst-Pernberg K, Wurmbach JH, Loges S, Kilic E, Weil J, Lauke H, Tilki D, Singer BB, Ergun S
    Blood, 2007;110(13):4223-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells.
    Authors: Lin YL, Liang YC, Chiang BL
    J. Leukoc. Biol., 2007;82(6):1473-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
    Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
    Crit. Care Med., 2007;35(8):1955-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  247. Impairment of the antifibrotic effect of hepatocyte growth factor in lung fibroblasts from African Americans: possible role in systemic sclerosis.
    Authors: Bogatkevich GS, Ludwicka-Bradley A, Highland KB, Hant F, Nietert PJ, Singleton CB, Feghali-Bostwick CA, Silver RM
    Arthritis Rheum., 2007;56(7):2432-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors.
    Authors: Ball SG, Shuttleworth CA, Kielty CM
    J. Cell Biol., 2007;177(3):489-500.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Enhancement of glucose transporter expression of brain endothelial cells by vascular endothelial growth factor derived from glioma exposed to hypoxia.
    Authors: Yeh WL, Lin CJ, Fu WM
    Mol. Pharmacol., 2007;73(1):170-7.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Thrombopoietin enhances generation of CD34+ cells from human embryonic stem cells.
    Authors: Srivastava AS, Nedelcu E, Esmaeli-Azad B, Mishra R, Carrier E
    Stem Cells, 2007;25(6):1456-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: identification of novel MSC subpopulations that respond to guidance cues in brain.
    Authors: Isakova IA, Baker K, Dutreil M, Dufour J, Gaupp D, Phinney DG
    Stem Cells, 2007;25(12):3261-70.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Fractalkine, a CX3C chemokine, as a mediator of ocular angiogenesis.
    Authors: You JJ, Yang CH, Huang JS, Chen MS, Yang CM
    Invest. Ophthalmol. Vis. Sci., 2007;48(11):5290-8.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting.
    Authors: Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, Bagri A, Tessier-Lavigne M, Koch AW, Watts RJ
    J. Biol. Chem., 2007;282(33):24049-56.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance
  254. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007;53(11):1990-5.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  255. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts.
    Authors: Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, Petrucci E, Cedrone M, Lo-Coco F, Foa R, Peschle C, Testa U
    Stem Cells, 2007;25(8):1862-71.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. The original Pathologische Anatomie Leiden-Endothelium monoclonal antibody recognizes a vascular endothelial growth factor binding site within neuropilin-1.
    Authors: Jaalouk DE, Ozawa MG, Sun J, Lahdenranta J, Schlingemann RO, Pasqualini R, Arap W
    Cancer Res., 2007;67(20):9623-9.
    Species: N/A
    Sample Types: Virus
    Applications: Bioassay
  257. Selective functional exhaustion of hematopoietic progenitor cells in the bone marrow of patients with postinfarction heart failure.
    Authors: Kissel CK, Lehmann R, Assmus B, Aicher A, Honold J, Fischer-Rasokat U, Heeschen C, Spyridopoulos I, Dimmeler S, Zeiher AM
    J. Am. Coll. Cardiol., 2007;49(24):2341-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. Evaluation of a xenogeneic VEGF vaccine in dogs with soft tissue sarcoma.
    Authors: Kamstock D, Elmslie R, Thamm D
    Cancer Immunol. Immunother., 2007;56(8):1299-309.
    Species: Canine
    Sample Types: In Vivo
    Applications: In Vivo
  259. Preclinical evaluation of antiangiogenic thrombospondin-1 peptide mimetics, ABT-526 and ABT-510, in companion dogs with naturally occurring cancers.
    Authors: Rusk A, McKeegan E, Haviv F, Majest S, Henkin J, Khanna C
    Clin. Cancer Res., 2006;12(24):7444-55.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1.
    Authors: Lake AC, Vassy R, Di Benedetto M, Lavigne D, Le Visage C, Perret GY, Letourneur D
    J. Biol. Chem., 2006;281(49):37844-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Multipotent adult progenitor cells from swine bone marrow.
    Authors: Zeng L, Rahrmann E, Hu Q, Lund T, Sandquist L, Felten M, O'Brien TD, O'Brien TD, Zhang J, Verfaillie C
    Stem Cells, 2006;24(11):2355-66.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Association between UHMWPE particle-induced inflammatory osteoclastogenesis and expression of RANKL, VEGF, and Flt-1 in vivo.
    Authors: Ren WP, Markel DC, Zhang R, Peng X, Wu B, Monica H, Wooley PH
    Biomaterials, 2006;27(30):5161-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  263. Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells.
    Authors: Hiroyama T, Miharada K, Aoki N, Fujioka T, Sudo K, Danjo I, Nagasawa T, Nakamura Y
    Exp. Hematol., 2006;34(6):760-9.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  264. Antagonists to human and mouse vascular endothelial growth factor receptor 2 generated by directed protein evolution in vitro.
    Authors: Getmanova EV, Chen Y, Bloom L, Gokemeijer J, Shamah S, Warikoo V, Wang J, Ling V, Sun L
    Chem. Biol., 2006;13(5):549-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Neurogenic effect of vascular endothelial growth factor during germ layer formation of human embryonic stem cells.
    Authors: Kim BK, Kim SE, Shim JH, Woo DH, Gil JE, Kim SK, Kim JH
    FEBS Lett., 2006;580(25):5869-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Hepatocyte growth factor induces retinal vascular permeability via MAP-kinase and PI-3 kinase without altering retinal hemodynamics.
    Authors: Clermont AC, Cahill M, Salti H, Rook SL, Rask-Madsen C, Goddard L, Wong JS, Bursell D, Bursell SE, Aiello LP
    Invest. Ophthalmol. Vis. Sci., 2006;47(6):2701-8.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  267. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2006;38(4):497-508.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Insulin-like growth factor binding protein-4 (IGFBP-4) is a novel anti-angiogenic and anti-tumorigenic mediator secreted by dibutyryl cyclic AMP (dB-cAMP)-differentiated glioblastoma cells.
    Authors: Moreno MJ, Ball M, Andrade MF, McDermid A, Stanimirovic DB
    Glia, 2006;53(8):845-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A.
    Authors: Nozaki M, Sakurai E, Raisler BJ, Baffi JZ, Witta J, Ogura Y, Brekken RA, Sage EH, Ambati BK, Ambati J
    J. Clin. Invest., 2006;116(2):422-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  270. Isolation of an adult blood-derived progenitor cell population capable of differentiation into angiogenic, myocardial and neural lineages.
    Authors: Porat Y, Porozov S, Belkin D, Shimoni D, Fisher Y, Belleli A, Czeiger D, Silverman WF, Belkin M, Battler A, Fulga V, Savion N
    Br. J. Haematol., 2006;135(5):703-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Interaction between Tie receptors modulates angiogenic activity of angiopoietin2 in endothelial progenitor cells.
    Authors: Kim KL, Shin IS, Kim JM, Choi JH, Byun J, Jeon ES, Suh W, Kim DK
    Cardiovasc. Res., 2006;72(3):394-402.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Inhibitory Smad transcription factors protect arterial endothelial cells from apoptosis induced by BMP4.
    Authors: Kiyono M, Shibuya M
    Oncogene, 2006;25(54):7131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Bactericidal/permeability-increasing protein's signaling pathways and its retinal trophic and anti-angiogenic effects.
    Authors: Yamagata M, Rook SL, Sassa Y, Ma RC, Geraldes P, Goddard L, Clermont A, Gao B, Salti H, Gundel R, White M, Feener EP, Aiello LP, King GL
    FASEB J., 2006;20(12):2058-67.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells.
    Authors: Sreekumar PG, Kannan R, de Silva AT, Burton R, Ryan SJ, Hinton DR
    Biochem. Biophys. Res. Commun., 2006;346(4):1200-6.
    Species: N/A
    Sample Types: N/A
    Applications: Western Blot
  275. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term.
    Authors: Bates DO, MacMillan PP, Manjaly JG, Qiu Y, Hudson SJ, Bevan HS, Hunter AJ, Soothill PW, Read M, Donaldson LF, Harper SJ
    Clin. Sci., 2006;110(5):575-85.
    Species: N/A
    Sample Types: N/A
    Applications: Western Blot
  276. Expression of DC-SIGN and DC-SIGNR on human sinusoidal endothelium: a role for capturing hepatitis C virus particles.
    Authors: Lai WK, Sun PJ, Zhang J, Jennings A, Lalor PF, Hubscher S, McKeating JA, Adams DH
    Am. J. Pathol., 2006;169(1):200-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration.
    Authors: Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F
    Blood, 2006;108(4):1243-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
    Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
    Cardiovasc. Res., 2006;69(4):925-35.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  279. Efficacy of systemic administration of SDF-1 in a model of vascular insufficiency: support for an endothelium-dependent mechanism.
    Authors: Carr AN, Howard BW, Yang HT, Eby-Wilkens E, Loos P, Varbanov A, Qu A, DeMuth JP, Davis MG, Proia A, Terjung RL, Peters KG
    Cardiovasc. Res., 2006;69(4):925-35.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  280. Specific involvement of SRC family kinase activation in the pathogenesis of retinal neovascularization.
    Authors: Werdich XQ, Penn JS
    Invest. Ophthalmol. Vis. Sci., 2006;47(11):5047-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Monocytes/macrophages cooperate with progenitor cells during neovascularization and tissue repair: conversion of cell columns into fibrovascular bundles.
    Authors: Anghelina M, Krishnan P, Moldovan L, Moldovan NI
    Am. J. Pathol., 2006;168(2):529-41.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  282. Regulation of Ang2 release by PTEN/PI3-kinase/Akt in lung microvascular endothelial cells.
    Authors: Tsigkos S, Zhou Z, Kotanidou A, Fulton D, Zakynthinos S, Roussos C, Papapetropoulos A
    J. Cell. Physiol., 2006;207(2):506-11.
    Species: Bovine
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  283. Ligand-induced internalization selects use of common receptor neuropilin-1 by VEGF165 and semaphorin3A.
    Authors: Narazaki M, Tosato G
    Blood, 2006;107(10):3892-901.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  284. Tal1/Scl gene transduction using a lentiviral vector stimulates highly efficient hematopoietic cell differentiation from common marmoset (Callithrix jacchus) embryonic stem cells.
    Authors: Kurita R, Sasaki E, Yokoo T, Hiroyama T, Takasugi K, Imoto H, Izawa K, Dong Y, Hashiguchi T, Soda Y, Maeda T, Suehiro Y, Tanioka Y, Nakazaki Y, Tani K
    Stem Cells, 2006;24(9):2014-22.
    Species: Primate - Callitrix jacchus (Common Marmoset)
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Osteoprotegerin (OPG)--a potential new role in the regulation of endothelial cell phenotype and tumour angiogenesis?
    Authors: Cross SS, Yang Z, Brown NJ, Balasubramanian SP, Evans CA, Woodward JK, Neville-Webbe HL, Lippitt JM, Reed MW, Coleman RE, Holen I
    Int. J. Cancer, 2006;118(8):1901-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Human peripheral blood eosinophils induce angiogenesis.
    Authors: Puxeddu I, Alian A, Piliponsky AM, Ribatti D, Panet A, Levi-Schaffer F
    Int. J. Biochem. Cell Biol., 2005;37(3):628-36.
    Species: Chicken
    Sample Types: Whole Tissue
    Applications: Bioassay
  287. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005;174(1):215-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  288. CXCR 3 activation promotes lymphocyte transendothelial migration across human hepatic endothelium under fluid flow.
    Authors: Curbishley SM, Eksteen B, Gladue RP, Lalor P, Adams DH
    Am. J. Pathol., 2005;167(3):887-99.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Microvascular patterning is controlled by fine-tuning the Akt signal.
    Authors: Sun JF, Phung T, Shiojima I, Felske T, Upalakalin JN, Feng D, Kornaga T, Dor T, Dvorak AM, Walsh K, Benjamin LE
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(1):128-33.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Pericytes and endothelial precursor cells: cellular interactions and contributions to malignancy.
    Authors: Bagley RG, Weber W, Rouleau C, Teicher BA
    Cancer Res., 2005;65(21):9741-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Normalization of coronary microvascular reactivity and improvement in myocardial perfusion by surgical vascular endothelial growth factor therapy combined with oral supplementation of l-arginine in a porcine model of endothelial dysfunction.
    Authors: Voisine P, Bianchi C, Khan TA, Ruel M, Xu SH, Feng J, Li J, Malik T, Rosinberg A, Sellke FW
    J. Thorac. Cardiovasc. Surg., 2005;129(6):1414-20.
    Species: Porcine
    Sample Types: In Vivo
    Applications: In Vivo
  292. Expression and activity of SRC regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis.
    Authors: Trevino JG, Summy JM, Gray MJ, Nilsson MB, Lesslie DP, Baker CH, Gallick GE
    Cancer Res., 2005;65(16):7214-22.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  293. VEGF164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2.
    Authors: Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP
    Invest. Ophthalmol. Vis. Sci., 2004;45(2):368-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties.
    Authors: Satchell SC, Anderson KL, Mathieson PW
    J. Am. Soc. Nephrol., 2004;15(3):566-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. GM-CSF induces expression of soluble VEGF receptor-1 from human monocytes and inhibits angiogenesis in mice.
    Authors: Eubank TD, Roberts R, Galloway M, Wang Y, Cohn DE, Marsh CB
    Immunity, 2004;21(6):831-42.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  296. VEGF-promoted surgical angiogenesis in necrotic bone.
    Authors: Suzuki O, Bishop AT, Sunagawa T, Katsube K, Friedrich PF
    Microsurgery, 2004;24(1):85-91.
    Species: Rabbit
    Sample Types: In Vivo
    Applications: In Vivo
  297. Inhibition of tumor growth and angiogenesis by soluble EphB4.
    Authors: Martiny-Baron G, Korff T, Schaffner F, Esser N, Eggstein S, Marme D, Augustin HG
    Neoplasia, 2004;6(3):248-57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein.
    Authors: Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R
    Int. J. Dev. Biol., 2003;47(1):15-29.
    Species: Xenopus
    Sample Types: In Vivo
    Applications: In Vivo
  299. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1.
    Authors: Caine GJ, Blann AD, Stonelake PS, Ryan P, Lip GY
    Eur. J. Clin. Invest., 2003;33(10):883-90.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  300. Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells.
    Authors: Fuller T, Korff T, Kilian A, Dandekar G, Augustin HG
    J. Cell. Sci., 2003;116(0):2461-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Expansion of human SCID-repopulating cells under hypoxic conditions.
    Authors: Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC
    J. Clin. Invest., 2003;112(1):126-35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3.
    Authors: Barbour AP, Reeder JA, Walsh MD, Fawcett J, Antalis TM, Gotley DC
    Cancer Res., 2003;63(4):887-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Binding Assay
  303. Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops.
    Authors: Masood R, Kundra A, Zhu S, Xia G, Scalia P, Smith DL, Gill PS
    Int. J. Cancer, 2003;104(5):603-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
    Authors: Maynard SE, Min JY, Merchan J, Lim KH, Mondal S, Stillman IE, Epstein FH, Karumanchi SA
    J. Clin. Invest., 2003;111(5):649-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Quantitative assessment of the integrity of the blood-retinal barrier in mice.
    Authors: Derevjanik NL, Vinores SA, Xiao WH, Mori K, Turon T, Hudish T, Dong S, Campochiaro PA
    Invest. Ophthalmol. Vis. Sci., 2002;43(7):2462-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  306. Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome.
    Authors: Keane MP, Donnelly SC, Belperio JA, Goodman RB, Dy M, Burdick MD, Fishbein MC, Strieter RM
    J. Immunol., 2002;169(11):6515-21.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  307. VEGF signaling is required for the assembly but not the maintenance of embryonic blood vessels.
    Authors: Argraves WS, Larue AC, Fleming PA, Drake CJ
    Dev. Dyn., 2002;225(3):298-304.
    Species: Avian - Quail
    Sample Types: In Vivo
    Applications: In Vivo
  308. 17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta.
    Authors: Gargett CE, Zaitseva M, Bucak K, Chu S, Fuller PJ, Rogers PA
    J. Clin. Endocrinol. Metab., 2002;87(9):4341-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. A critical role of placental growth factor in the induction of inflammation and edema formation.
    Authors: Oura H, Bertoncini J, Velasco P, Brown LF, Carmeliet P, Detmar M
    Blood, 2002;101(2):560-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  310. Role of matrix metalloproteinase-9 in angiogenesis caused by ocular infection with herpes simplex virus.
    Authors: Lee S, Zheng M, Kim B, Rouse BT
    J. Clin. Invest., 2002;110(8):1105-11.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  311. Antiangiogenic gene therapy for cancer via systemic administration of adenoviral vectors expressing secretable endostatin.
    Authors: Chen CT, 2018, Lin J, Li Q, Phipps SS, Jakubczak JL, Stewart DA, Skripchenko Y, Forry-Schaudies S, Wood J, Schnell C, Hallenbeck PL
    132, 2000;11(14):1983-96.
  312. The dineolignan from Saururus chinensis, manassantin B, inhibits tumor-induced angiogenesis via downregulation of matrix metalloproteinases 9 in human endothelial cells.
    Authors: Liu, Zhaojie, Lu, Hong, Liu, Rong, Chen, Bin, Wang, Shan, Ma, Junchao, Fu, Jianjian
    Oncol Rep, 0;32(2):659-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

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Reviews for Recombinant Human VEGF 165 Protein

Average Rating: 4.8 (Based on 23 Reviews)

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Recombinant Human VEGF 165 Protein
By Anonymous on 12/10/2018
Application: Cell migration/motility

Recombinant Human VEGF 165 Protein
By Anonymous on 11/26/2018
Application: Immunoassay Standard

The recombinant human VEGF protein was used as the calibration reagent in MSD assay with biotinylated MAB293 (capture) and Sulfo-Tag labeled AF-293-NA (detection) antibodies.


Recombinant Human VEGF 165 Protein
By Anonymous on 10/15/2018
Application: CellProlif

Recombinant Human VEGF 165 Protein
By Anonymous on 08/22/2018
Application: Stem/Immune cell maintenance or differentiation

Recombinant Human VEGF 165 Protein
By Anonymous on 03/22/2018
Application: SDS-PAGE Control

Recombinant Human VEGF 165 Protein
By Anonymous on 02/08/2018
Application: SDS-PAGE Control

Recombinant Human VEGF 165 Protein
By Anonymous on 12/01/2017
Application: CellProlif

Recombinant Human VEGF 165 Protein
By Anonymous on 11/18/2017
Application: Binding assay/Protein-protein interaction

Recombinant Human VEGF 165 Protein
By Anonymous on 11/10/2017
Application: SPR(SURFACE PLASMA RESONANCE)

Recombinant Human VEGF 165 Protein
By Anonymous on 10/20/2017
Application: preeclampsia study, Genomics

Recombinant Human VEGF 165 Protein
By Anonymous on 08/23/2017
Application: In vitro bioactivity in cell culture

Recombinant Human VEGF 165 Protein
By Anonymous on 08/15/2017
Application: In vivo study

Recombinant Human VEGF 165 Protein
By Anonymous on 08/15/2017
Application: Binding assay/Protein-protein interaction

Recombinant Human VEGF 165 Protein
By Anonymous on 06/13/2017
Application: Cell migration/motility
Reason for Rating: Very good agonist and I always see a very good response with VEGF-A on retinal endothelial migration and it also highly induces various signaling proteins.

I have used at 40 ng/ml concentration in a serum-free media both for cell migration and cell signaling (western blots).


Recombinant Human VEGF 165 Protein
By Anonymous on 05/15/2017

Recombinant Human VEGF 165 Protein
By Anonymous on 05/03/2017

Recombinant Human VEGF 165 Protein
By Anonymous on 12/15/2016
Application: Stem/Immune cell maintenance or differentiation

Human Recombinant VEGF165 protein is a cornerstone reagent for our protocol which looks to differentiate induced pluripotent stem cells into endothelial cells (ECs). Activin A and BMP-4 purchased from R&D was also utilized in the initial differentiation stages in combination with VEGF165. We routinely perform this differentiation protocol and VEGF165 has been reliable in expanding iPSC-derived ECs to sufficient quantities required for us to recellularize rat lung scaffolds which have been decellularized.


Recombinant Human VEGF 165 Protein
By Anonymous on 12/15/2016
Application: Stem/Immune cell maintenance or differentiation

rhVEGF is used to induce differentiation of iPSC to cardiomyotcyes.


Recombinant Human VEGF 165 Protein
By Anonymous on 12/15/2016
Application: Stem/Immune cell maintenance or differentiation

We use VEGF in a variety of iPSC differentiations. The differeniations include; endothelial, hematopoietic, and hepatoctye to name a few. There has been no lot to lot variability, all lots have preformed the same across multiple experiments.


Recombinant Human VEGF 165 Protein
By Anonymous on 08/19/2016
Application: Media additive for protein or antibody production

Recombinant Human VEGF 165 Protein
By Anonymous on 08/12/2016
Application: CellProlif

Recombinant Human VEGF 165 Protein
By Anonymous on 06/08/2016
Application: VEGF 165 was used to induce neurite growth from sensory neurons. In the picture, primary trigeminal ganglia neuron treated with 50 ng/ml VEGF 165 after 3 days in culture showed extensive neurite growth.

Recombinant Human VEGF 165 Protein
By Anonymous on 01/13/2016
Application: CellProlif