Recombinant Mouse IFN-gamma Protein

Formulations:
Catalog # Availability Size / Price Qty
485-MI-100
Recombinant Mouse IFN-gamma Protein Data
2 Images
Product Details
Citations (284)
FAQs
Reviews (9)

Recombinant Mouse IFN-gamma Protein Summary

Purity
>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in an anti-viral assay using L‑929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. Vogel, S.N. et al. (1982) Infect. Immunol. 38:681. The ED50 for this effect is 0.3-0.9 ng/mL.
Source
E. coli-derived mouse IFN-gamma protein
His23-Cys155, with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
15.6 kDa
SDS-PAGE
11-12 kDa, reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

485-MI

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol,Tween® 80 and TCEP with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

485-MI/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol,Tween® 80 and TCEP with Trehalose.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity View Larger

Recombinant Mouse IFN-gamma (Catalog # 485-ML) demonstrates anti-viral activity in L-929 mouse fibroblast cells infected with encephalomyocarditis (EMC) virus. The ED50for this effect is 0.3-0.9 ng/mL.

SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IFN-gamma was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 11-12 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IFN-gamma

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2). Mature mouse IFN-gamma exists as a noncovalently linked homodimer of 20-25 kDa variably glycosylated subunits (3). It shares 86% amino acid sequence identity with rat IFN-gamma and 38%-44% with bovine, canine, cotton rat, equine, feline, human, porcine, and rhesus IFN-gamma. IFN-gamma dimers bind to IFN‑ gamma RI (alpha subunits) which then interact with IFN-gamma RII (beta subunits) to form the functional receptor complex of two alpha and two beta subunits. Inclusion of IFN-gamma RII increases the binding affinity for ligand and the efficiency of signal transduction (4, 5). IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells (6). It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, up-regulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects (6, 7). In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation (8, 9). The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis (7).

References
  1. Billiau, A. and P. Matthys (2009) Cytokine Growth Factor Rev. 20:97.
  2. Pestka, S. et al. (2004) Immunol. Rev. 202:8.
  3. Gray, P.W. and D.V. Goeddel (1983) Proc. Natl. Acad. Sci. 80:5842.
  4. Marsters, S.A. et al. (1995) Proc. Natl. Acad. Sci. 92:5401.
  5. Krause, C.D. et al. (2000) J. Biol. Chem. 275:22995.
  6. Schroder, K. et al. (2004) J. Leukoc. Biol. 75:163.
  7. McLaren, J.E. and D.P. Ramji (2009) Cytokine Growth Factor Rev. 20:125.
  8. Muhl, H. and J. Pfeilschifter (2003) Int. Immunopharmacol. 3:1247.
  9. Kelchtermans, H. et al. (2008) Trends Immunol. 29:479.
Long Name
Interferon gamma
Entrez Gene IDs
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
Alternate Names
IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma

Citations for Recombinant Mouse IFN-gamma Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

284 Citations: Showing 1 - 10
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  1. Microbiota-driven interleukin-17 production provides immune protection against invasive candidiasis
    Authors: M Li, C Li, X Wu, T Chen, L Ren, B Xu, J Cao
    Crit Care, 2020;24(1):268.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  2. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress
    Authors: M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura
    Haematologica, 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  3. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells
    Authors: S Steinmann, M Schoedsack, F Heinrich, PC Breda, A Ochel, G Tiegs, K Neumann
    Sci Rep, 2020;10(1):1071.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  4. N6-methyladenosine demethylase FTO promotes M1 and M2 macrophage activation
    Authors: X Gu, Y Zhang, D Li, H Cai, L Cai, Q Xu
    Cell. Signal., 2020;0(0):109553.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  5. Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
    Authors: K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito
    BMC Cancer, 2020;20(1):25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  6. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells
    Authors: J Falero-Per, N Sheibani, CM Sorenson
    PLoS ONE, 2020;15(5):e0232779.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Role of pyruvate kinase M2-mediated metabolic reprogramming during podocyte differentiation
    Authors: Q Yuan, J Miao, Q Yang, L Fang, Y Fang, H Ding, Y Zhou, L Jiang, C Dai, K Zen, Q Sun, J Yang
    Cell Death Dis, 2020;11(5):355.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Cycling hypoxia promotes a pro-inflammatory phenotype in macrophages via JNK/p65 signaling pathway
    Authors: V Delprat, C Tellier, C Demazy, M Raes, O Feron, C Michiels
    Sci Rep, 2020;10(1):882.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Paracrine regulation and improvement of &beta-cell function by thioredoxin
    Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
    Redox Biol, 2020;34(0):101570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  10. Myeloid Slc2a1-Deficient Murine Model Revealed Macrophage Activation and Metabolic Phenotype Are Fueled by GLUT1
    Authors: AJ Freemerman, L Zhao, AK Pingili, B Teng, AJ Cozzo, AM Fuller, AR Johnson, JJ Milner, MF Lim, JA Galanko, MA Beck, JE Bear, JD Rotty, L Bezavada, HS Smallwood, MA Puchowicz, J Liu, JW Locasale, DP Lee, BJ Bennett, ED Abel, JC Rathmell, L Makowski
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  11. Blunting neuroinflammation with resolvin D1 prevents early pathology in a rat model of Parkinson's disease
    Authors: P Krashia, A Cordella, A Nobili, L La Barbera, M Federici, A Leuti, F Campanelli, G Natale, G Marino, V Calabrese, F Vedele, V Ghiglieri, B Picconi, G Di Lazzaro, T Schirinzi, G Sancesario, N Casadei, O Riess, S Bernardini, A Pisani, P Calabresi, MT Viscomi, CN Serhan, V Chiurchiù, M D'Amelio, NB Mercuri
    Nat Commun, 2019;10(1):3945.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  12. Trabectedin Reduces Skeletal Prostate Cancer Tumor Size in Association with Effects on M2 Macrophages and Efferocytosis
    Authors: JD Jones, BP Sinder, D Paige, FN Soki, AJ Koh, S Thiele, Y Shiozawa, LC Hofbauer, S Daignault, H Roca, LK McCauley
    Neoplasia, 2019;21(2):172-184.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation
    Authors: Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan
    Sci Rep, 2019;9(1):1022.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
    Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
    Br. J. Cancer, 2019;121(7):556-566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. IL-33 deficiency causes persistent inflammation and severe neurodegeneration in retinal detachment
    Authors: J Augustine, S Pavlou, I Ali, K Harkin, E Ozaki, M Campbell, AW Stitt, H Xu, M Chen
    J Neuroinflammation, 2019;16(1):251.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. The combination of Radix Astragali and Radix Angelicae Sinensis attenuates the IFN-gamma-induced immune destruction of hematopoiesis in bone marrow cells
    Authors: J Liu, J Wei, C Wang, X Meng, H Chen, P Deng, M Huandike, H Zhang, X Li, L Chai
    BMC Complement Altern Med, 2019;19(1):356.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Metabolic regulation of gene expression by histone lactylation
    Authors: D Zhang, Z Tang, H Huang, G Zhou, C Cui, Y Weng, W Liu, S Kim, S Lee, M Perez-Neut, J Ding, D Czyz, R Hu, Z Ye, M He, YG Zheng, HA Shuman, L Dai, B Ren, RG Roeder, L Becker, Y Zhao
    Nature, 2019;574(7779):575-580.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  18. Macrophage miR-34a Is a Key Regulator of Cholesterol Efflux and Atherosclerosis
    Authors: Y Xu, Y Xu, Y Zhu, H Sun, C Juguilon, F Li, D Fan, L Yin, Y Zhang
    Mol. Ther., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. A20 as an immune tolerance factor can determine islet transplant outcomes
    Authors: NW Zammit, SN Walters, KL Seeberger, PJ O'Connell, GS Korbutt, ST Grey
    JCI Insight, 2019;4(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
    Authors: M Kita, Y Ano, A Inoue, J Aoki
    Sci Rep, 2019;9(1):3135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. The combination of Cytokines and albendazole therapy for prophylaxis and treatment of experimental./hydatid cyst
    Authors: M Rahdar, A Rafiei, R Valipour-N
    Acta Trop., 2019;201(0):105206.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  22. Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury
    Authors: C Claser, SYT Nguee, A Balachande, S Wu Howland, E Becht, B Gunasegara, SV Hartimath, AWQ Lee, J Theng Then, C Bing Ong, EW Newell, J Goggi, L Guan Ng, L Renia
    Nat Commun, 2019;10(1):4241.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
    Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Theaflavins Improve Memory Impairment and Depression-Like Behavior by Regulating Microglial Activation
    Authors: Y Ano, R Ohya, M Kita, Y Taniguchi, K Kondo
    Molecules, 2019;24(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Phlda3 regulates beta cell survival during stress
    Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
    Sci Rep, 2019;9(1):12827.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis
    Authors: H Lindahl, AO Guerreiro-, SK Bedri, M Linnerbaue, M Lindén, N Abdelmagid, K Tandre, C Hollins, L Irving, C Glover, C Jones, L Alfredsson, L Rönnblom, I Kockum, M Khademi, M Jagodic, T Olsson
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  27. Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe
    Authors: PM Ryan, EH Stolte, LEE London, JM Wells, SL Long, SA Joyce, CGM Gahan, GF Fitzgerald, RP Ross, NM Caplice, C Stanton
    BMC Microbiol., 2019;19(1):33.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein
    Authors: PAM Cavalcante, N Alenina, A Budu, LC Freitas-Li, T Alves-Silv, JSH Agudelo, F Qadri, NOS Camara, M Bader, RC Araújo
    Mediators Inflamm., 2019;2019(0):9086758.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  29. SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm
    Authors: TA Nguyen, BRC Smith, KD Elgass, SJ Creed, S Cheung, MD Tate, GT Belz, IP Wicks, SL Masters, KC Pang
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  30. The Rho/MRTF pathway inhibitor CCG-222740 reduces stellate cell activation and modulates immune cell populations in KrasG12D; Pdx1-Cre (KC) mice
    Authors: AS Leal, SA Misek, EM Lisabeth, RR Neubig, KT Liby
    Sci Rep, 2019;9(1):7072.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Genetic Screen in Chlamydia muridarum Reveals Role for an Interferon-Induced Host Cell Death Program in Antimicrobial Inclusion Rupture
    Authors: AM Giebel, S Hu, K Rajaram, R Finethy, E Toh, JA Brothwell, SG Morrison, RJ Suchland, BD Stein, J Coers, RP Morrison, DE Nelson
    MBio, 2019;10(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Vitamin D improves sunburns by increasing autophagy in M2 macrophages
    Authors: LM Das, AM Binko, ZP Traylor, H Peng, KQ Lu
    Autophagy, 2019;0(0):1-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
    Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
    Nat. Med., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Signal regulatory protein ? protects podocytes through promoting autophagic activity
    Authors: L Li, Y Liu, S Li, Y Yang, C Zeng, W Rong, H Liang, M Zhang, X Zhu, K Kidder, Y Liu, Z Liu, K Zen
    JCI Insight, 2019;5(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model
    Authors: Y Nakamura, S Miyagawa, S Yoshida, S Sasawatari, T Toyofuku, K Toda, Y Sawa
    Sci Rep, 2019;9(1):10840.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. MUC16 suppresses human and murine innate immune responses
    Authors: M Felder, A Kapur, AL Rakhmilevi, X Qu, PM Sondel, SD Gillies, J Connor, MS Patankar
    Gynecol. Oncol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Maternal Type-I interferon signaling adversely affects the microglia and the behavior of the offspring accompanied by increased sensitivity to stress
    Authors: H Ben-Yehuda, O Matcovitch, A Kertser, A Spinrad, M Prinz, I Amit, M Schwartz
    Mol. Psychiatry, 2019;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  39. Tetrahydrocurcumin Enhances Islet Cell Function and Attenuates Apoptosis in Mouse Islets
    Authors: SS Kim, HJ Jang, MY Oh, JH Lee, KS Kang
    Transplant. Proc., 2018;50(9):2847-2853.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Innate and adaptive signals enhance differentiation and expansion of dual-antibody autoreactive B cells in lupus
    Authors: A Sang, T Danhorn, JN Peterson, AL Rankin, BP O'Connor, SM Leach, RM Torres, R Pelanda
    Nat Commun, 2018;9(1):3973.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
    Authors: C Sun, SY Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
    Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
    Mol Metab, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Weighted Gene Correlation Network Analysis (WGCNA) Detected Loss of MAGI2 Promotes Chronic Kidney Disease (CKD) by Podocyte Damage
    Authors: Z Zuo, JX Shen, Y Pan, J Pu, YG Li, XH Shao, WP Wang
    Cell. Physiol. Biochem., 2018;51(1):244-261.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Role of IL-18 induced Amphiregulin expression on virus induced ocular lesions
    Authors: SK Varanasi, NK Rajasagi, U Jaggi, BT Rouse
    Mucosal Immunol, 2018;0(0):.
    Species: Mouse
    Sample Types:
  45. Induced pluripotent stem cells-derived myeloid-derived suppressor cells regulate the CD8+ T cell response
    Authors: D Joyce, M Fujino, M Morita, R Araki, J Fung, S Qian, L Lu, XK Li
    Stem Cell Res, 2018;29(0):32-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Total Flavonoids from Radix Glycyrrhiza Exert Anti-Inflammatory and Antitumorigenic Effects by Inactivating iNOS Signaling Pathways
    Authors: YX Jiang, YY Dai, YF Pan, XM Wu, Y Yang, K Bian, DD Zhang
    Evid Based Complement Alternat Med, 2018;2018(0):6714282.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
    Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
    Front Immunol, 2018;9(0):22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. SOCS3 deficiency in myeloid cells promotes retinal degeneration and angiogenesis through arginase-1 up-regulation in experimental autoimmune uveoretinitis
    Authors: M Chen, J Zhao, IH Ali, S Marry, J Augustine, M Bhuckory, A Lynch, A Kissenpfen, H Xu
    Am. J. Pathol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
    Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
    Neurobiol. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  50. PEDF Expression Affects the Oxidative and Inflammatory State of Choroidal Endothelial Cells
    Authors: M Farnoodian, CM Sorenson, N Sheibani
    Am. J. Physiol., Cell Physiol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
    Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
    Sci Rep, 2018;8(1):8414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. In vitro evaluation of the anti-leishmanial activity and toxicity of PK11195
    Authors: CES Guedes, BRS Dias, ALOA Petersen, KP Cruz, NJ Almeida, DR Andrade, JPB Menezes, VM Borges, PST Veras
    Mem. Inst. Oswaldo Cruz, 2018;113(4):e170345.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
    Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
    EMBO Mol Med, 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  54. AMPK Activation Regulates LTBP4-Dependent TGF-?1 Secretion by Pro-inflammatory Macrophages and Controls Fibrosis in Duchenne Muscular Dystrophy
    Authors: G Juban, M Saclier, H Yacoub-You, A Kernou, L Arnold, C Boisson, S Ben Larbi, M Magnan, S Cuvellier, M Théret, BJ Petrof, I Desguerre, J Gondin, R Mounier, B Chazaud
    Cell Rep, 2018;25(8):2163-2176.e6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Human papillomavirus E7 oncoprotein expression by keratinocytes alters the cytotoxic mechanisms used by CD8 T cells
    Authors: P Bhat, AS Bergot, N Waterhouse, IH Frazer
    Oncotarget, 2018;9(5):6015-6027.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Disease-specific oligodendrocyte lineage cells arise in multiple sclerosis
    Authors: AM Falcão, D van Brugge, S Marques, M Meijer, S Jäkel, E Agirre, Samudyata, EM Floriddia, DP Vanichkina, C Ffrench-Co, A Williams, AO Guerreiro-, G Castelo-Br
    Nat. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
    Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
    Biol. Reprod., 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  58. Loss of Paneth Cell Autophagy Causes Acute Susceptibility to Toxoplasma gondii-Mediated Inflammation
    Authors: E Burger, A Araujo, A López-Ygle, MW Rajala, L Geng, B Levine, LV Hooper, E Burstein, F Yarovinsky
    Cell Host Microbe, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Stimulation
  59. Loss of NF-?B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner
    Authors: LA O'Reilly, TL Putoczki, LA Mielke, JT Low, A Lin, A Preaudet, MJ Herold, K Yaprianto, L Tai, A Kueh, G Pacini, RL Ferrero, R Gugasyan, Y Hu, M Christie, S Wilcox, R Grumont, MDW Griffin, L O'Connor, GK Smyth, M Ernst, P Waring, S Gerondakis, A Strasser
    Immunity, 2018;48(3):570-583.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Collagen-derived peptides modulate CD4T-cell differentiation and suppress allergic responses in mice
    Authors: A Nishikimi, YI Koyama, S Ishihara, S Kobayashi, C Tometsuka, M Kusubata, K Kuwaba, O Hayashida, S Hattori, K Katagiri
    Immun Inflamm Dis, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Protection against Staphylococcus aureus Colonization and Infection by B- and T-Cell-Mediated Mechanisms
    Authors: F Zhang, O Ledue, M Jun, C Goulart, R Malley, YJ Lu
    MBio, 2018;9(5):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  62. PGC-1? ameliorates kidney fibrosis in mice with diabetic kidney disease through an antioxidative mechanism
    Authors: L Zhang, J Liu, F Zhou, W Wang, N Chen
    Mol Med Rep, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  64. A20 upregulation during treated HIV disease is associated with intestinal epithelial cell recovery and function
    Authors: AS Chitre, MG Kattah, YY Rosli, M Pao, M Deswal, SG Deeks, PW Hunt, M Abdel-Mohs, LJ Montaner, CC Kim, A Ma, M Somsouk, JM McCune
    PLoS Pathog., 2018;14(3):e1006806.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  65. Plectin protects podocytes from adriamycin-induced apoptosis and F-actin cytoskeletal disruption through the integrin ?6?4/FAK/p38 MAPK pathway
    Authors: Y Ni, X Wang, X Yin, Y Li, X Liu, H Wang, X Liu, J Zhang, H Gao, B Shi, S Zhao
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Mesenchymal stem cells ameliorate experimental arthritis via expression of interleukin-1 receptor antagonist
    Authors: K Lee, N Park, H Jung, YA Rim, Y Nam, J Lee, SH Park, JH Ju
    PLoS ONE, 2018;13(2):e0193086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Reduction of MHC-I expression limits T-lymphocyte-mediated killing of Cancer-initiating cells
    Authors: BJ Morrison, JC Steel, JC Morris
    BMC Cancer, 2018;18(1):469.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Circular RNAs as novel regulators of ?-cell functions in normal and disease conditions
    Authors: L Stoll, J Sobel, A Rodriguez-, C Guay, K Lee, MT Venø, J Kjems, DR Laybutt, R Regazzi
    Mol Metab, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. The deficiency of CX3CL1/CX3CR1 system ameliorates high fructose diet-induced kidney injury by regulating NF-κB pathways in CX3CR1-knock out mice
    Authors: YW Yu, MX Li, ZY Zhang, H Yu
    Int. J. Mol. Med., 2018;41(6):3577-3585.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche
    Authors: YM Nusse, AK Savage, P Marangoni, AKM Rosendahl-, TA Landman, FJ de Sauvage, RM Locksley, OD Klein
    Nature, 2018;559(7712):109-113.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  71. Roles of Exosome-Like Vesicles Released from Inflammatory C2C12 Myotubes: Regulation of Myocyte Differentiation and Myokine Expression
    Authors: S Kim, MJ Lee, JY Choi, DH Park, HB Kwak, S Moon, JW Koh, HK Shin, JK Ryu, CS Park, JH Park, JH Kang
    Cell. Physiol. Biochem., 2018;48(5):1829-1842.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  72. REV-ERB? Regulates TH17 Cell Development and Autoimmunity
    Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
    Cell Rep, 2018;25(13):3733-3749.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice
    Authors: Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu
    Cell Death Dis, 2018;9(7):760.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Mycobacterium tuberculosis PPE60 antigen drives Th1/Th17 responses via Toll-like receptor 2-dependent maturation of dendritic cells
    Authors: H Su, Z Zhang, Z Liu, B Peng, C Kong, H Wang, Z Zhang, Y Xu
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Astaxanthin exerts anti-inflammatory and antioxidant effects in macrophages in NRF2-dependent and independent manners
    Authors: C Farruggia, MB Kim, M Bae, Y Lee, TX Pham, Y Yang, MJ Han, YK Park, JY Lee
    J. Nutr. Biochem., 2018;62(0):202-209.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
    Authors: E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén
    Sci Rep, 2018;8(1):13600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Tumor-Repopulating Cells Induce PD-1 Expression in CD8+T Cells by Transferring Kynurenine and AhR Activation
    Authors: Y Liu, X Liang, W Dong, Y Fang, J Lv, T Zhang, R Fiskesund, J Xie, J Liu, X Yin, X Jin, D Chen, K Tang, J Ma, H Zhang, J Yu, J Yan, H Liang, S Mo, F Cheng, Y Zhou, H Zhang, J Wang, J Li, Y Chen, B Cui, ZW Hu, X Cao, F Xiao-Feng, B Huang
    Cancer Cell, 2018;33(3):480-494.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells
    Authors: J Falero-Per, YS Song, Y Zhao, L Teixeira, CM Sorenson, N Sheibani
    PLoS ONE, 2018;13(10):e0206756.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. BCL6-Mediated Silencing of PD-1 Ligands in Germinal Center B Cells Maintains Follicular T Cell Population
    Authors: C Peng, Q Hu, F Yang, H Zhang, F Li, C Huang
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Astrocytic orosomucoid-2 modulates microglial activation and neuroinflammation
    Authors: M Jo, JH Kim, G Song, M Seo, E Mi Hwang, K Suk
    J. Neurosci, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma
    Authors: A K Kosmides
    Biomaterials, 2017;118(0):16-26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy
    Authors: SA Samant, A Kanwal, VB Pillai, R Bao, MP Gupta
    Sci Rep, 2017;7(1):11877.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
    Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
    Cardiovasc Diabetol, 2017;16(1):143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Metabolic origins of spatial organization in the tumor microenvironment
    Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Interferon-? derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
    Authors: P Bhat, G Leggatt, N Waterhouse, IH Frazer
    Cell Death Dis, 2017;8(6):e2836.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Characterisation of iunH gene knockout strain from Mycobacterium tuberculosis
    Authors: AD Villela, VD Rodrigues, AF Pinto, PL Wink, ZA Sánchez-Qu, GO Petersen, MM Campos, LA Basso, DS Santos
    Mem. Inst. Oswaldo Cruz, 2017;112(3):203-208.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
    Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
    Cell Death Discov, 2017;3(0):16097.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
    Authors: MG Ledesma-Co, N Adán, G Ortiz, M Solís-Guti, F López-Barr, G Martínez d, C Clapp
    Arthritis Res. Ther., 2017;19(1):93.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  89. Robust growth of avirulent phase II Coxiella burnetii in bone marrow-derived murine macrophages
    Authors: DC Cockrell, CM Long, SJ Robertson, JG Shannon, HE Miller, L Myers, CL Larson, T Starr, PA Beare, RA Heinzen
    PLoS ONE, 2017;12(3):e0173528.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. MicroRNA-27a promotes podocyte injury via PPAR?-mediated ?-catenin activation in diabetic nephropathy
    Authors: Z Zhou, J Wan, X Hou, J Geng, X Li, X Bai
    Cell Death Dis, 2017;8(3):e2658.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice
    Authors: J Lau, J Cheung, A Navarro, S Lianoglou, B Haley, K Totpal, L Sanders, H Koeppen, P Caplazi, J McBride, H Chiu, R Hong, J Grogan, V Javinal, R Yauch, B Irving, M Belvin, I Mellman, JM Kim, M Schmidt
    Nat Commun, 2017;8(0):14572.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  92. A Rab20-Dependent Membrane Trafficking Pathway Controls M.�tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity
    Authors: L Schnettger, A Rodgers, U Repnik, RP Lai, G Pei, M Verdoes, RJ Wilkinson, DB Young, MG Gutierrez
    Cell Host Microbe, 2017;21(5):619-628.e5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
    Authors: V Piccolo, A Curina, M Genua, S Ghisletti, M Simonatto, A Sabò, B Amati, R Ostuni, G Natoli
    Nat. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Modulation of Roquin Function in Myeloid Cells Reduces Mycobacterium tuberculosis-Induced Inflammation
    Authors: G Nagalingam, CG Vinuesa, WJ Britton, BM Saunders
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Pathogen-mediated manipulation of arthropod microbiota to promote infection
    Authors: NM Abraham, L Liu, BL Jutras, AK Yadav, S Narasimhan, V Gopalakris, JM Ansari, KK Jefferson, F Cava, C Jacobs-Wag, E Fikrig
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(5):E781-E790.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  96. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
    Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
    Sci Rep, 2017;7(0):42846.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Therapeutic reversal of food allergen sensitivity by mature retinoic acid-differentiated dendritic cell induction of LAG3(+)CD49b(-)Foxp3(-) regulatory T�cells
    Authors: W Dawicki, C Li, J Town, X Zhang, JR Gordon
    J. Allergy Clin. Immunol., 2017;139(5):1608-1620.e3.
    Species: Mouse
    Sample Types: Serum
    Applications: ELISA (Standard)
  98. IL-10 down-regulates the expression of survival associated gene hspX of Mycobacterium tuberculosis in murine macrophage
    Authors: B Jee, P Sharma, K Katoch, B Joshi, SK Awasthi
    Braz J Infect Dis, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid
    Authors: CA Sorgi, S Zarini, SA Martin, RL Sanchez, RF Scandiuzzi, MA Gijón, C Guijas, N Flamand, RC Murphy, LH Faccioli
    Sci Rep, 2017;7(1):10981.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4(+) memory T cells
    Authors: BA Szilagyi, J Triebus, C Kressler, M de Almeida, S Tierling, P Durek, M Mardahl, A Szilagyi, S Floess, J Huehn, U Syrbe, J Walter, JK Polansky, A Hamann
    Mucosal Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Conditionally Immortal Slc4a11-/- Mouse Corneal Endothelial Cell Line Recapitulates Disrupted Glutaminolysis Seen in Slc4a11-/- Mouse Model
    Authors: W Zhang, DG Ogando, ET Kim, MJ Choi, H Li, JM Tenessen, JA Bonanno
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3723-3731.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. CD4(+)CD8?(+) double-positive T cells in skin-draining lymph nodes respond to inflammatory signals from the skin
    Authors: NH Overgaard, JL Cruz, JA Bridge, HJ Nel, IH Frazer, NL La Gruta, A Blumenthal, RJ Steptoe, JW Wells
    J. Leukoc. Biol., 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  103. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
    Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
    Sci Rep, 2017;7(1):5107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B
    Authors: J Braverman, SA Stanley
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis
    Authors: MA L‚cuyer, O Saint-Laur, L BourbonniŠ, S Larouche, C Larochelle, L Michel, M Charabati, M Abadier, S Zandee, N Haghayegh, E Gowing, C Pittet, R Lyck, B Engelhardt, A Prat
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(4):E524-E533.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Interleukin 4 receptor-targeted pro-apoptotic peptide blocks tumor growth and metastasis by enhancing anti-tumor immunity
    Authors: SMP Vadevoo, JE Kim, GR Gunassekar, HK Jung, L Chi, DE Kim, SH Lee, SH Im, B Lee
    Mol. Cancer Ther., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages
    Authors: AJ Morales, JA Carrero, PJ Hung, AT Tubbs, JM Andrews, BT Edelson, B Calderon, CL Innes, RS Paules, JE Payton, BP Sleckman
    Elife, 2017;6(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Pancreatic ?-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF)
    Authors: DA Cunha, M Cito, FA Grieco, C Cosentino, T Danilova, L Ladriere, M Lindahl, A Domanskyi, M Bugliani, P Marchetti, DL Eizirik, M Cnop
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Microglia activation is essential for BMP7-mediated retinal reactive gliosis
    Authors: S Dharmaraja, DL Fisk, CM Sorenson, N Sheibani, TL Belecky-Ad
    J Neuroinflammation, 2017;14(1):76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. STAT3 promotes IFN?/TNF?-induced muscle wasting in an NF-?B-dependent and IL-6-independent manner
    Authors: JF Ma, BJ Sanchez, DT Hall, AK Tremblay, S Di Marco, IE Gallouzi
    EMBO Mol Med, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  111. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
    Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
    Nat Commun, 2017;8(0):14919.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells
    Authors: S Iwata, Y Mikami, HW Sun, SR Brooks, D Jankovic, K Hirahara, A Onodera, HY Shih, T Kawabe, K Jiang, T Nakayama, A Sher, JJ O'Shea, FP Davis, Y Kanno
    Immunity, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression
    Authors: R Ahn, V Sabourin, AM Bolt, S Hébert, S Totten, N De Jay, MC Festa, YK Young, YK Im, T Pawson, AE Koromilas, WJ Muller, KK Mann, CL Kleinman, J Ursini-Sie
    Nat Commun, 2017;8(0):14638.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. TRIM21 is critical for survival of Toxoplasma gondii infection and localises to GBP-positive parasite vacuoles
    Authors: C Foltz, A Napolitano, R Khan, B Clough, EM Hirst, EM Frickel
    Sci Rep, 2017;7(1):5209.
  115. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
    Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
    J. Nutr. Biochem, 2017;44(0):11-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
    Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
    EBioMedicine, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  117. The inhibition of NLRP3 signaling attenuates liver injury in an ?-galactosylceramide-induced hepatitis model
    Authors: A Kanbe, H Ito, Y Omori, A Hara, M Seishima
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Applications: ELISA (Standard)
  118. CD11b regulates antibody class switching via induction of AID
    Authors: S Park, H Sim, HI Kim, D Jeong, G Wu, SY Cho, YS Lee, HJ Kwon, K Lee
    Mol. Immunol., 2017;87(0):47-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients
    Authors: L Quinti, S Dayalan Na, U Träger, X Chen, K Kegel-Glea, D Llères, C Connolly, V Chopra, C Low, S Moniot, E Sapp, AR Tousley, P Vodicka, MJ Van Kanega, LS Kaltenbach, LA Crawford, M Fuszard, M Higgins, JRC Miller, RE Farmer, V Potluri, S Samajdar, L Meisel, N Zhang, A Snyder, R Stein, SM Hersch, LM Ellerby, E Weerapana, MA Schwarzsch, C Steegborn, BR Leavitt, A Degterev, SJ Tabrizi, DC Lo, M DiFiglia, LM Thompson, AT Dinkova-Ko, AG Kazantsev
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Co-encapsulation and co-transplantation of mesenchymal stem cells reduces pericapsular fibrosis and improves encapsulated islet survival and function when allografted
    Authors: V Vaithiling, MDM Evans, DM Lewy, PA Bean, S Bal, BE Tuch
    Sci Rep, 2017;7(1):10059.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. The IL-1RI Co-Receptor TILRR (FREM1�Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease
    Authors: SA Smith, AO Samokhin, M Alfadi, EC Murphy, D Rhodes, WML Holcombe, E Kiss-Toth, RF Storey, SP Yee, SE Francis, EE Qwarnstrom
    JACC Basic Transl Sci, 2017;2(4):398-414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
    Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
    J. Allergy Clin. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis
    Authors: C Shimojima, H Takeuchi, S Jin, B Parajuli, H Hattori, A Suzumura, H Hibi, M Ueda, A Yamamoto
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Elastin-Derived Peptides Promote Abdominal Aortic Aneurysm Formation by Modulating M1/M2 Macrophage Polarization
    J Immunol, 2016;196(11):4536-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. G2A Signaling Dampens Colitic Inflammation via Production of IFN-?
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  126. Mechanisms Underlying Interferon-?-Induced Priming of Microglial Reactive Oxygen Species Production
    PLoS ONE, 2016;11(9):e0162497.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
    JCI Insight, 2016;1(14):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Th1 cells downregulate connexin 43 gap junctions in astrocytes via microglial activation
    Sci Rep, 2016;6(0):38387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Dimethyl fumarate alters microglia phenotype and protects neurons against proinflammatory toxic microenvironments
    Authors: Haiyan Peng
    J. Neuroimmunol, 2016;299(0):35-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Identification and Function of Fibrocytes in Skeletal Muscle Injury Repair and Muscular Dystrophy
    J. Immunol., 2016;197(12):4750-4761.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription
    Nat Commun, 2016;7(0):11624.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Individual and interactive sex-specific effects of acute restraint and systemic IFN-? treatment on neurochemistry
    Authors: Shawn Hayley
    Neurochem. Int., 2016;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  134. Proteasome Activators, PA28? and PA28?, Govern Development of Microvascular Injury in Diabetic Nephropathy and Retinopathy
    Authors: Ali Mahmoudpou
    Int J Nephrol, 2016;2016(0):3846573.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Application of genetically engineered Salmonella typhimurium for interferon-gamma-induced therapy against melanoma
    Authors: Byeong Mo Kim
    Eur. J. Cancer, 2016;70(0):48-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Context-Specific and Immune Cell-Dependent Antitumor Activities of ?1-Antitrypsin
    Authors: Ofer Guttman
    Front Immunol, 2016;7(0):559.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Early infiltration of p40IL12(+)CCR7(+)CD11b(+) cells is critical for fibrosis development
    Authors: Niels Olsen Saraiva Camara
    Immun Inflamm Dis, 2016;4(3):300-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
    Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
    J. Biol. Chem., 2016;291(30):15830-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages
    Authors: L R Batista-Si
    Sci Rep, 2016;6(0):27632.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
    Circ Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
    Nat Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Anti-Tumor and Immune Enhancing Activities of Rice Bran Gramisterol on Acute Myelogenous Leukemia.
    Authors: Somintara S, Leardkamolkarn V, Suttiarporn P, Mahatheeranont S
    PLoS ONE, 2016;11(1):e0146869.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Macrophages form functional vascular mimicry channels in vivo
    Sci Rep, 2016;6(0):36659.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  145. Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei
    PLoS Negl Trop Dis, 2016;10(8):e0004907.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
    Sci Rep, 2016;6(0):37211.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
    Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
    Oncogene, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Platelets Guide Leukocytes to Their Sites of Extravasation
    PLoS Biol, 2016;14(5):e1002459.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  149. Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.
    Authors: Doench J, Fusi N, Sullender M, Hegde M, Vaimberg E, Donovan K, Smith I, Tothova Z, Wilen C, Orchard R, Virgin H, Listgarten J, Root D
    Nat Biotechnol, 2016;34(2):184-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016;6(0):37977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Epobis is a Nonerythropoietic and Neuroprotective Agonist of the Erythropoietin Receptor with Anti-Inflammatory and Memory Enhancing Effects
    Authors: Oksana Dmytriyeva
    Mediators Inflamm, 2016;2016(0):1346390.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. NADPH oxidases are essential for macrophage differentiation
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Tumor-intrinsic PD-L1 signals regulate cell growth, pathogenesis and autophagy in ovarian cancer and melanoma
    Cancer Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Horizontal transfer of exosomal microRNAs transduce apoptotic signals between pancreatic beta-cells.
    Authors: Guay C, Menoud V, Rome S, Regazzi R
    Cell Commun Signal, 2015;13(0):17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
    Autophagy, 2015;11(2):271-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Defining immunological impact and therapeutic benefit of mild heating in a murine model of arthritis.
    Authors: Lee C, Kokolus K, Leigh N, Capitano M, Hylander B, Repasky E
    PLoS ONE, 2015;10(3):e0120327.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Disruption of an M. tuberculosis membrane protein causes a magnesium-dependent cell division defect and failure to persist in mice.
    Authors: Goodsmith N, Guo X, Vandal O, Vaubourgeix J, Wang R, Botella H, Song S, Bhatt K, Liba A, Salgame P, Schnappinger D, Ehrt S
    PLoS Pathog, 2015;11(2):e1004645.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
    Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
    J Immunol, 2015;195(9):4415-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.
    Authors: Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, Birrell M, Saijo S, Mostowy S, Shaunak S, Armstrong-James D
    EMBO Mol Med, 2015;7(3):240-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Distinct functions of epidermal and myeloid-derived VEGF-A in skin tumorigenesis mediated by HPV8.
    Authors: Ding X, Lucas T, Marcuzzi G, Pfister H, Eming S
    Cancer Res, 2015;75(2):330-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
    Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
    J Immunol, 2015;195(8):3531-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Protective role for caspase-11 during acute experimental murine colitis.
    Authors: Oficjalska K, Raverdeau M, Aviello G, Wade S, Hickey A, Sheehan K, Corr S, Kay E, O'Neill L, Mills K, Creagh E
    J Immunol, 2015;194(3):1252-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Nuclear export inhibitors avert progression in preclinical models of inflammatory demyelination.
    Authors: Haines J, Herbin O, de la Hera B, Vidaurre O, Moy G, Sun Q, Fung H, Albrecht S, Alexandropoulos K, McCauley D, Chook Y, Kuhlmann T, Kidd G, Shacham S, Casaccia P
    Nat Neurosci, 2015;18(4):511-20.
    Species: Mouse
    Sample Types: In Vivo
  164. Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences.
    Authors: Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D
    J Invest Dermatol, 2015;135(7):1771-80.
  165. Positive feedback regulation of type I IFN production by the IFN-inducible DNA sensor cGAS.
    Authors: Ma F, Li B, Liu S, Iyer S, Yu Y, Wu A, Cheng G
    J Immunol, 2015;194(4):1545-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Glycogen Synthase Kinase-3beta (GSK-3beta) Inhibition Enhances Dendritic Cell-based Cancer Vaccine Potency via Suppression of Interferon-gamma-induced Indoleamine 2,3-Dioxygenase Expression.
    Authors: Noh K, Son K, Jung I, Kang T, Choi C, Park Y
    J Biol Chem, 2015;290(19):12394-402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Dynamics of Circulating gammadelta T Cell Activity in an Immunocompetent Mouse Model of High-Grade Glioma.
    Authors: Beck B, Kim H, O'Brien R, Jadus M, Gillespie G, Cloud G, Hoa N, Langford C, Lopez R, Harkins L, Lamb L
    PLoS ONE, 2015;10(5):e0122387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.
    Authors: Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G
    Genes Dev, 2015;29(4):394-408.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Interferon Gamma, but not Calcitriol Improves the Osteopetrotic Phenotypes in ADO2 Mice.
    Authors: Alam I, Gray A, Acton D, Gerard-O'Riley R, Reilly A, Econs M
    J Bone Miner Res, 2015;30(11):2005-13.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  170. Activated Brain Endothelial Cells Cross-Present Malaria Antigen.
    Authors: Howland S, Poh C, Renia L
    PLoS Pathog, 2015;11(6):e1004963.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. IFN-gamma Prevents Adenosine Receptor (A2bR) Upregulation To Sustain the Macrophage Activation Response.
    Authors: Cohen H, Ward A, Hamidzadeh K, Ravid K, Mosser D
    J Immunol, 2015;195(8):3828-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. The cholesterol transporter ABCG1 links cholesterol homeostasis and tumour immunity.
    Authors: Sag D, Cekic C, Wu R, Linden J, Hedrick C
    Nat Commun, 2015;6(0):6354.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
    Authors: Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H
    Eur J Immunol, 2015;45(9):2494-503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  174. MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration.
    Authors: Cebrian C, Zucca F, Mauri P, Steinbeck J, Studer L, Scherzer C, Kanter E, Budhu S, Mandelbaum J, Vonsattel J, Zecca L, Loike J, Sulzer D
    Nat Commun, 2014;5(0):3633.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
    Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
    J Immunol, 2014;193(6):3036-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. IL-13 orchestrates resolution of chronic intestinal inflammation via phosphorylation of glycogen synthase kinase-3beta.
    Authors: Fichtner-Feigl S, Kesselring R, Martin M, Obermeier F, Ruemmele P, Kitani A, Brunner S, Haimerl M, Geissler E, Strober W, Schlitt H
    J Immunol, 2014;192(8):3969-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Intramolecular polyspecificity in CD4 T-cell recognition of Ad-restricted epitopes of proteoglycan aggrecan.
    Authors: Falconer J, Lowes K, Furmanski A, Dyson J, Ng W, Robinson J
    Immunology, 2014;142(1):101-110.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
    Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
    Elife, 2014;3(0):e02809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. The primary cilium influences interleukin-1beta-induced NFkappaB signalling by regulating IKK activity.
    Authors: Wann A, Chapple J, Knight M
    Cell Signal, 2014;26(8):1735-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Interferon regulatory factor 1 restricts gammaherpesvirus replication in primary immune cells.
    Authors: Mboko W, Mounce B, Emmer J, Darrah E, Patel S, Tarakanova V
    J Virol, 2014;88(12):6993-7004.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
    Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
    J Immunol, 2014;192(1):59-72.
  182. USP18 is crucial for IFN-gamma-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity.
    Authors: Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, Yi Q
    Mol Cancer, 2014;13(0):132.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury.
    Authors: Dohi, Kenji, Kraemer, Brian C, Erickson, Michelle, McMillan, Pamela J, Kovac, Andrej, Flachbartova, Zuzana, Hansen, Kim M, Shah, Gul N, Sheibani, Nader, Salameh, Therese, Banks, William
    PLoS ONE, 2014;9(9):e108034.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Improved repair of dermal wounds in mice lacking microRNA-155.
    Authors: van Solingen C, Araldi E, Chamorro-Jorganes A, Fernandez-Hernando C, Suarez Y
    J Cell Mol Med, 2014;18(6):1104-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Curcumin ameliorates autoimmune diabetes. Evidence in accelerated murine models of type 1 diabetes.
    Authors: Castro C, Barcala Tabarrozzi A, Winnewisser J, Gimeno M, Antunica Noguerol M, Liberman A, Paz D, Dewey R, Perone M
    Clin Exp Immunol, 2014;177(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
    Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
    Mucosal Immunol, 2014;7(4):818-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis.
    Authors: Stoolman J, Duncker P, Huber A, Segal B
    J Immunol, 2014;193(2):564-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Mesenchymal stem cells use IDO to regulate immunity in tumor microenvironment.
    Authors: Ling W, Zhang J, Yuan Z, Ren G, Zhang L, Chen X, Rabson A, Roberts A, Wang Y, Shi Y
    Cancer Res, 2014;74(5):1576-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. All-trans retinoic acid induces arginase-1 and inducible nitric oxide synthase-producing dendritic cells with T cell inhibitory function.
    Authors: Bhatt S, Qin J, Bennett C, Qian S, Fung J, Hamilton T, Lu L
    J Immunol, 2014;192(11):5098-108.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Essential role of CD11a in CD8+ T-cell accumulation and activation in adipose tissue.
    Authors: Jiang E, Perrard X, Yang D, Khan I, Perrard J, Smith C, Ballantyne C, Wu H
    Arterioscler Thromb Vasc Biol, 2014;34(1):34-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. A novel immunomodulatory function of PHLPP1: inhibition of iNOS via attenuation of STAT1 ser727 phosphorylation in mouse macrophages.
    Authors: Alamuru N, Behera S, Butchar J, Tridandapani S, Kaimal Suraj S, Babu P, Hasnain S, Ehtesham N, Parsa K
    J Leukoc Biol, 2014;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Recombinant Wnt3a and Wnt5a elicit macrophage cytokine production and tolerization to microbial stimulation via Toll-like receptor 4.
    Authors: Yu C, Nguyen T, Irvine K, Sweet M, Frazer I, Blumenthal A
    Eur J Immunol, 2014;44(5):1480-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
    Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
    J Immunol, 2014;192(1):103-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Control of intracellular Francisella tularensis by different cell types and the role of nitric oxide.
    Authors: Newstead S, Gates A, Hartley M, Rowland C, Williamson E, Lukaszewski R
    J Immunol Res, 2014;2014(0):694717.
  196. Paneth cell extrusion and release of antimicrobial products is directly controlled by immune cell-derived IFN-gamma.
    Authors: Farin H, Karthaus W, Kujala P, Rakhshandehroo M, Schwank G, Vries R, Kalkhoven E, Nieuwenhuis E, Clevers H
    J Exp Med, 2014;211(7):1393-405.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  197. Delineating the importance of serum opsonins and the bacterial capsule in affecting the uptake and killing of Burkholderia pseudomallei by murine neutrophils and macrophages.
    Authors: Mulye M, Bechill M, Grose W, Ferreira V, Lafontaine E, Wooten R
    PLoS Negl Trop Dis, 2014;8(8):e2988.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Collective nitric oxide production provides tissue-wide immunity during Leishmania infection.
    Authors: Olekhnovitch R, Ryffel B, Muller A, Bousso P
    J Clin Invest, 2014;124(4):1711-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma.
    Authors: Shibata T, Habiel D, Coelho A, Kunkel S, Lukacs N, Hogaboam C
    J Immunol, 2014;192(8):3569-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Luminex (Standard)
  200. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  201. NK cells are required for dendritic cell-based immunotherapy at the time of tumor challenge.
    Authors: Bouwer A, Saunderson S, Caldwell F, Damani T, Pelham S, Dunn A, Jack R, Stoitzner P, McLellan A
    J Immunol, 2014;192(5):2514-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  203. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014;5(0):4436.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Peroxisome proliferator-activated receptor alpha protects capillary pericytes in the retina.
    Authors: Ding L, Cheng R, Hu Y, Takahashi Y, Jenkins A, Keech A, Humphries K, Gu X, Elliott M, Xia X, Ma J
    Am J Pathol, 2014;184(10):2709-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Synergistic up-regulation of CXCL10 by virus and IFN gamma in human airway epithelial cells.
    Authors: Oslund K, Zhou X, Lee B, Zhu L, Duong T, Shih R, Baumgarth N, Hung L, Wu R, Chen Y
    PLoS ONE, 2014;9(7):e100978.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  206. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
    Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
    PLoS ONE, 2014;9(3):e90829.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Suppression of Th1-mediated autoimmunity by embryonic stem cell-derived dendritic cells.
    Authors: Ikeda T, Hirata S, Takamatsu K, Haruta M, Tsukamoto H, Ito T, Uchino M, Ando Y, Nagafuchi S, Nishimura Y, Senju S
    PLoS ONE, 2014;9(12):e115198.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
    Authors: Steelman A, Smith R, Welsh C, Li J
    J Biol Chem, 2014;288(33):23776-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Endothelial cell-derived chemerin promotes dendritic cell transmigration.
    Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
    J Immunol, 2014;192(5):2366-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Steady-state antigen scavenging, cross-presentation, and CD8+ T cell priming: a new role for lymphatic endothelial cells.
    Authors: Hirosue S, Vokali E, Raghavan V, Rincon-Restrepo M, Lund A, Corthesy-Henrioud P, Capotosti F, Halin Winter C, Hugues S, Swartz M
    J Immunol, 2014;192(11):5002-11.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Regulation of experimental autoimmune encephalomyelitis by TPL-2 kinase.
    Authors: Sriskantharajah S, Guckel E, Tsakiri N, Kierdorf K, Brender C, Ben-Addi A, Veldhoen M, Tsichlis P, Stockinger B, O'Garra A, Prinz M, Kollias G, Ley S
    J Immunol, 2014;192(8):3518-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. IL-9-producing invariant NKT cells protect against DSS-induced colitis in an IL-4-dependent manner.
    Authors: Kim H, Chung D
    Mucosal Immunol, 2013;6(2):347-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma.
    Authors: Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S
    PLoS ONE, 2013;8(4):e61446.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Differentially imprinted innate immunity by mucosal boost vaccination determines antituberculosis immune protective outcomes, independent of T-cell immunity.
    Authors: Jeyanathan M, Damjanovic D, Shaler C, Lai R, Wortzman M, Yin C, Zganiacz A, Lichty B, Xing Z
    Mucosal Immunol, 2013;6(3):612-25.
  216. CD43-mediated IFN-gamma production by CD8+ T cells promotes abdominal aortic aneurysm in mice.
    Authors: Zhou H, Yan H, Cannon J, Springer L, Green J, Pham C
    J Immunol, 2013;190(10):5078-85.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  217. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013;288(18):12699-711.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  218. The exonuclease Trex1 restrains macrophage proinflammatory activation.
    Authors: Pereira-Lopes S, Celhar T, Sans-Fons G, Serra M, Fairhurst A, Lloberas J, Celada A
    J Immunol, 2013;191(12):6128-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. IL-4/IL-13-dependent and independent expression of miR-124 and its contribution to M2 phenotype of monocytic cells in normal conditions and during allergic inflammation.
    Authors: Veremeyko, Tatyana, Siddiqui, Shafiudd, Sotnikov, Ilya, Yung, Amanda, Ponomarev, Eugene D
    PLoS ONE, 2013;8(12):e81774.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Association of beta-catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF-beta1.
    Authors: Tian X, Zhang J, Tan T, Lyons J, Zhao H, Niu B, Lee S, Tsatralis T, Zhao Y, Wang Y, Cao Q, Wang C, Wang Y, Lee V, Kahn M, Zheng G, Harris D
    J Cell Sci, 2013;126(0):67-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Cannabinoid 1 receptors in keratinocytes modulate proinflammatory chemokine secretion and attenuate contact allergic inflammation.
    Authors: Gaffal E, Cron M, Glodde N, Bald T, Kuner R, Zimmer A, Lutz B, Tuting T
    J Immunol, 2013;190(10):4929-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Everolimus limits aortic aneurysm in the apolipoprotein E-deficient mouse by downregulating C-C chemokine receptor 2 positive monocytes.
    Authors: Moran C, Jose R, Moxon J, Roomberg A, Norman P, Rush C, Korner H, Golledge J
    Arterioscler Thromb Vasc Biol, 2013;33(4):814-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Regulation and migratory role of P-selectin ligands during intestinal inflammation.
    Authors: Hoffmann U, Pink M, Lauer U, Heimesaat M, Winsauer C, Kruglov A, Schlawe K, Leichsenring C, Liesenfeld O, Hamann A, Syrbe U
    PLoS ONE, 2013;8(4):e62055.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Guanylate-binding protein 1 (Gbp1) contributes to cell-autonomous immunity against Toxoplasma gondii.
    Authors: Selleck E, Fentress S, Beatty W, Degrandi D, Pfeffer K, Virgin H, Macmicking J, Sibley L
    PLoS Pathog, 2013;9(4):e1003320.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. An antioxidant role for catecholate siderophores in Salmonella.
    Authors: Achard, Maud E S, Chen, Kaiwen W, Sweet, Matthew, Watts, Rebecca, Schroder, Kate, Schembri, Mark A, McEwan, Alastair
    Biochem J, 2013;454(3):543-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Endoglin regulates the activation and quiescence of endothelium by participating in canonical and non-canonical TGF-beta signaling pathways.
    Authors: Park S, Dimaio T, Liu W, Wang S, Sorenson C, Sheibani N
    J Cell Sci, 2013;126(0):1392-405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Calmodulin-dependent protein kinase II/cAMP response element-binding protein/Wnt/beta-catenin signaling cascade regulates angiotensin II-induced podocyte injury and albuminuria.
    Authors: Jiang L, Xu L, Song Y, Li J, Mao J, Zhao A, He W, Yang J, Dai C
    J Biol Chem, 2013;288(32):23368-79.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. ATP release and autocrine signaling through P2X4 receptors regulate gammadelta T cell activation.
    Authors: Manohar M, Hirsh M, Chen Y, Woehrle T, Karande A, Junger W
    J Leukoc Biol, 2012;92(4):787-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2012;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  230. IL-6 mediates the susceptibility of glycoprotein 130 hypermorphs to Toxoplasma gondii.
    J. Immunol., 2012;187(1):350-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Interferon gamma inhibits adipogenesis in vitro and prevents marrow fat infiltration in oophorectomized mice.
    Authors: Vidal C, Bermeo S, Li W, Huang D, Kremer R, Duque G
    Stem Cells, 2012;30(5):1042-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  232. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Development of an IL-15-autocrine CD8 T-cell leukemia in IL-15-transgenic mice requires the cis expression of IL-15R alpha.
    Authors: Sato N, Sabzevari H, Fu S, Ju W, Petrus MN, Bamford RN, Waldmann TA, Tagaya Y
    Blood, 2011;117(15):4032-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. The C5a receptor impairs IL-12-dependent clearance of Porphyromonas gingivalis and is required for induction of periodontal bone loss.
    Authors: Liang S, Krauss JL, Domon H, McIntosh ML, Hosur KB, Qu H, Li F, Tzekou A, Lambris JD, Hajishengallis G
    J. Immunol., 2011;186(2):869-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Hematopoietic cell-restricted deletion of CD36 reduces high-fat diet-induced macrophage infiltration and improves insulin signaling in adipose tissue.
    Authors: Nicholls HT, Kowalski G, Kennedy DJ
    Diabetes, 2011;60(4):1100-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Phosphatidylinositol 3-kinase/protein kinase Cdelta activation induces close homolog of adhesion molecule L1 (CHL1) expression in cultured astrocytes.
    Authors: Wu J, Wrathall JR, Schachner M
    Glia, 2010;58(3):315-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Commensal microflora and interferon-gamma promote steady-state interleukin-7 production in vivo.
    Authors: Shalapour S, Deiser K, Sercan O, Tuckermann J, Minnich K, Willimsky G, Blankenstein T, Hammerling GJ, Arnold B, Schuler T
    Eur. J. Immunol., 2010;40(9):2391-400.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. IL-18 production downstream of the Nlrp3 inflammasome confers protection against colorectal tumor formation.
    Authors: Zaki MH, Vogel P, Body-Malapel M, Lamkanfi M, Kanneganti TD
    J. Immunol., 2010;185(8):4912-20.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  239. Proinflammatory clearance of apoptotic neutrophils induces an IL-12(low)IL-10(high) regulatory phenotype in macrophages.
    Authors: Filardy AA, Pires DR, Nunes MP, Takiya CM, Freire-de-Lima CG, Ribeiro-Gomes FL, DosReis GA
    J. Immunol., 2010;185(4):2044-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  240. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2010;3(1):40-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
    Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
    J. Immunol., 2010;185(7):4354-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  242. Cure of established GL261 mouse gliomas after combined immunotherapy with GM-CSF and IFNgamma is mediated by both CD8+ and CD4+ T-cells.
    Authors: Smith KE, Fritzell S, Badn W, Eberstal S, Janelidze S, Visse E, Darabi A, Siesjo P
    Int. J. Cancer, 2009;124(3):630-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  243. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009;183(4):2642-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10.
    Authors: Ilarregui JM, Croci DO, Bianco GA, Toscano MA, Salatino M, Vermeulen ME, Geffner JR, Rabinovich GA
    Nat. Immunol., 2009;10(9):981-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
    Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
    Nature, 2009;460(7252):269-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009;206(1):69-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. Effects of Signal 3 during CD8 T cell priming: Bystander production of IL-12 enhances effector T cell expansion but promotes terminal differentiation.
    Authors: Cui W, Joshi NS, Jiang A, Kaech SM
    Vaccine, 2009;27(15):2177-87.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  248. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009;11(4):524-30.
  249. Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNgamma production.
    Authors: Lemos HP, Grespan R, Vieira SM, Cunha TM, Verri WA, Fernandes KS, Souto FO, McInnes IB, Ferreira SH, Liew FY, Cunha FQ
    Proc. Natl. Acad. Sci. U.S.A., 2009;106(14):5954-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  250. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. IFN-gamma down-regulates Secretoglobin 3A1 gene expression.
    Authors: Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, Takami M, Donnelly RP, Itabe H, Yamamoto M, Kimura S, Kamijo R
    Biochem. Biophys. Res. Commun., 2009;379(4):964-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Vaccination route that induces transforming growth factor beta production fails to elicit protective immunity against Leishmania donovani infection.
    Authors: Bhowmick S, Mazumdar T, Ali N
    Infect. Immun., 2009;77(4):1514-23.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008;125(2):272-9.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  254. Interferon-gamma limits the availability of iron for intramacrophage Salmonella typhimurium.
    Authors: Nairz M, Fritsche G, Brunner P, Talasz H, Hantke K, Weiss G
    Eur. J. Immunol., 2008;38(7):1923-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.
    Authors: Liu T, Huang Y, Likhotvorik RI, Keshvara L, Hoyt DG
    Am. J. Physiol., Cell Physiol., 2008;295(3):C819-27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007;245(2):70-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  257. IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
    Authors: Lee YM, Miyahara N, Takeda K, Prpich J, Oh A, Balhorn A, Joetham A, Gelfand EW, Dakhama A
    Am. J. Respir. Crit. Care Med., 2007;177(2):208-18.
  258. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
    Authors: Schell JB, Crane CA, Smith MF, Roberts MR
    J. Neuroimmunol., 2007;189(1):75-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration.
    Authors: Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ
    Am. J. Pathol., 2007;170(5):1695-712.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007;27(40):10695-702.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  261. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
    Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
    J Ethnopharmacol, 2006;106(3):418-24.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  262. Differential Growth of IFN-beta-Engineered Tumor Cells in Nude and IFN Receptor-Null Mice.
    Authors: Zhang F, Lee J, Wang D, Dong Z
    J. Interferon Cytokine Res., 2006;26(2):108-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
    Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
    J. Immunol., 2006;177(12):8650-7.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  264. Targeted deletion of CCR2 impairs deep vein thombosis resolution in a mouse model.
    Authors: Henke PK, Pearce CG, Moaveni DM, Moore AJ, Lynch EM, Longo C, Varma M, Dewyer NA, Deatrick KB, Upchurch GR, Wakefield TW, Hogaboam C, Kunkel SL
    J. Immunol., 2006;177(5):3388-97.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  265. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
    Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
    Mol. Cell. Neurosci., 2006;31(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis.
    Authors: Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M
    J. Clin. Invest., 2006;116(4):905-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
    Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(31):11784-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Dendritic cells and NK cells stimulate bystander T cell activation in response to TLR agonists through secretion of IFN-alpha beta and IFN-gamma.
    Authors: Kamath AT, Sheasby CE, Tough DF
    J. Immunol., 2005;174(2):767-76.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  269. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005;79(20):12828-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005;302(1):172-81.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  271. A disintegrin and metalloproteinase 10-mediated cleavage and shedding regulates the cell surface expression of CXC chemokine ligand 16.
    Authors: Gough PJ, Garton KJ, Wille PT, Rychlewski M, Dempsey PJ, Raines EW
    J. Immunol., 2004;172(6):3678-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection.
    Authors: Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT
    J. Biol. Chem., 2004;279(52):54405-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Gamma interferon does not enhance clearance of Pseudomonas aeruginosa but does amplify a proinflammatory response in a murine model of postseptic immunosuppression.
    Authors: Murphey ED, Herndon DN, Sherwood ER
    Infect. Immun., 2004;72(12):6892-901.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  274. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004;21(2):241-54.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  275. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
    Authors: Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB
    J. Immunol., 2004;172(10):6476-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004;172(12):7408-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Impact of interleukin-13 responsiveness on the synthetic and proliferative properties of Th1- and Th2-type pulmonary granuloma fibroblasts.
    Authors: Jakubzick C, Choi ES, Kunkel SL, Joshi BH, Puri RK, Hogaboam CM
    Am. J. Pathol., 2003;162(5):1475-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Mouse strain differences in plasmacytoid dendritic cell frequency and function revealed by a novel monoclonal antibody.
    Authors: Asselin-Paturel C, Brizard G, Pin JJ, Briere F, Trinchieri G
    J. Immunol., 2003;171(12):6466-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Cooperative B7-1/2 (CD80/CD86) and B7-DC costimulation of CD4+ T cells independent of the PD-1 receptor.
    Authors: Shin T, Kennedy G, Gorski K, Tsuchiya H, Koseki H, Azuma M, Yagita H, Chen L, Powell J, Pardoll D, Housseau F
    J. Exp. Med., 2003;198(1):31-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Intracellular thiols contribute to Th2 function via a positive role in IL-4 production.
    Authors: Monick MM, Samavati L, Butler NS, Mohning M, Powers LS, Yarovinsky T, Spitz DR, Hunninghake GW
    J. Immunol., 2003;171(10):5107-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  281. IFN-gamma, but not Fas, mediates reduction of allergen-induced mucous cell metaplasia by inducing apoptosis.
    Authors: Shi ZO, Fischer MJ, De Sanctis GT, Schuyler MR, Tesfaigzi Y
    J. Immunol., 2002;168(9):4764-71.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  282. Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection.
    Authors: Bosteels C, Neyt K, Vanheerswynghels M, van Helden M, Sichien D, Debeuf N, De Prijck S, Bosteels V, Vandamme N, Martens L, Saeys Y, Louagie E, Lesage M, Williams D, Tang S, Mayer J, Ronchese F, Scott C, Hammad H, Guilliams M, Lambrecht B
    Immunity, 0;0(0):.
    Species: Mouse
    Sample Types: cell culture
  283. TGFbeta2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion.
    Authors: Craig EA, Craig E, Austin A, Austin AF, Vaillancourt RR, Vaillancourt R, Barnett JV, Camenisch T, Camenisch TD
    Exp Cell Res, 0;316(20):3397-405.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Tumor-derived granzyme B-expressing neutrophils acquire antitumor potential after lipid A treatment.
    Authors: A Martin, C Seignez, C Racoeur, N Isambert, Isambert N, Mabrouk N, N Mabrouk, A Scagliarin, Scagliarini A, Reveneau S, S Reveneau, L Arnould, Arnould L, A Bettaieb, JF Jeannin, Jeannin J, C Paul
    Oncotarget, 0;9(47):28364-28378.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay

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Recombinant Mouse IFN-gamma Protein
By Anonymous on 10/09/2020
Application: In vitro bioactivity in cell culture

Balb/c Mice solenocytes were treated with mrIFN-gamma and the intracellular IDO-1 expression was measured in CD45/CD11c+ population


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Application: In vitro bioactivity in cell culture

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Application: In vitro bioactivity in cell culture

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Application: In vitro bioactivity in cell culture