Recombinant Mouse IL-1 beta/IL-1F2 Protein

Formulations:
Catalog # Availability Size / Price Qty
401-ML-005
401-ML-025
401-ML-010
401-ML-100
401-ML-01M
Recombinant Mouse IL-1 beta/IL-1F2 Protein Data
2 Images
Product Details
Citations (172)
FAQs
Supplemental Products
Reviews (7)

Recombinant Mouse IL-1 beta/IL-1F2 Protein Summary

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED50 for this effect is 2-10 pg/mL.
Source
E. coli-derived mouse IL-1 beta/IL-1F2 protein
Val118-Ser269, with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
17 kDa

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

401-ML

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

401-ML/CF

Formulation Supplied as a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in PBS.
Shipping The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

Data Images

Bioactivity View Larger

Recombinant Mouse IL-1 beta /IL-1F2 (Catalog # 401-ML) stimulates cell proliferation of the D10.G4.1 mouse helper T cell line. The ED50for this effect is 2‑10 pg/mL.

SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IL1 beta /IL-1F2 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 19 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-1 beta/IL-1F2

IL-1 is a name that designates two pleiotropic cytokines, IL-1 alpha (IL-1F1) and IL-1 beta (IL-1F2), which are the products of distinct genes. IL-1 alpha and IL-1 beta are structurally related polypeptides that share approximately 17% amino acid (aa) identity in mouse. Both proteins are produced by a wide variety of cells in response to inflammatory agents, infections, or microbial endotoxins. While IL-1 alpha and IL-1 beta are regulated independently, they bind to the same receptor and exert identical biological effects. IL-1 RI binds directly to IL-1 alpha or IL-1 beta and then associates with IL-1 R accessory protein (IL-1 R3/IL-1 R AcP) to form a high-affinity receptor complex that is competent for signal transduction. IL-1 RII has high affinity for IL-1 beta but functions as a decoy receptor and negative regulator of IL-1 beta activity. IL-1ra functions as a competitive antagonist by preventing IL-1 alpha and IL-1 beta from interacting with IL-1 RI (1-4). The mouse IL-1 beta cDNA encodes a 269 aa precursor. A 117 aa propeptide is cleaved intracellularly by the cysteine protease IL-1 beta -converting enzyme (Caspase-1/ICE) to generate the active cytokine (5, 6). The 17 kDa mature mouse IL-1 beta shares 90% aa sequence identity with cotton rat and rat and 65%-78% identity with canine, equine, feline, human, porcine, and rhesus IL-1 beta.

References
  1. Allan, S.M. et al. (2005) Nat. Rev. Immunol. 5:629.
  2. Boraschi, D. and A. Tagliabue (2006) Vitam. Horm. 74:229.
  3. Kornman, K.S. (2006) Am. J. Clin. Nutr. 83:475S.
  4. Isoda, K. and F. Ohsuzu (2006) J. Atheroscler. Thromb. 13:21.
  5. Gray, P.W. et al. (1986) J. Immunol. 137:3644.
  6. Martinon, F. and J. Tschopp (2007) Cell Death Differ. 14:10.
Long Name
Interleukin 1 beta
Entrez Gene IDs
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Citations for Recombinant Mouse IL-1 beta/IL-1F2 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

172 Citations: Showing 1 - 10
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  1. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
    Authors: B Hou, Y Zhang, P Liang, Y He, B Peng, W Liu, S Han, J Yin, X He
    Cell Death Dis, 2020;11(5):377.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Signal-transducing adaptor protein-2 delays recovery of B lineage lymphocytes during hematopoietic stress
    Authors: M Ichii, K Oritani, J Toda, H Saito, H Shi, H Shibayama, D Motooka, Y Kitai, R Muromoto, JI Kashiwakur, K Saitoh, D Okuzaki, T Matsuda, Y Kanakura
    Haematologica, 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  3. Paracrine regulation and improvement of &beta-cell function by thioredoxin
    Authors: EM Hanschmann, SF Petry, S Eitner, CC Maresch, N Lingwal, CH Lillig, T Linn
    Redox Biol, 2020;34(0):101570.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  4. Noggin Inhibits IL-1&beta and BMP-2 Expression, and Attenuates Cartilage Degeneration and Subchondral Bone Destruction in Experimental Osteoarthritis
    Authors: SY Chien, CH Tsai, SC Liu, CC Huang, TH Lin, YZ Yang, CH Tang
    Cells, 2020;9(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  5. MiR-21-5p regulates extracellular matrix degradation and angiogenesis in TMJOA by targeting Spry1
    Authors: S Ma, A Zhang, X Li, S Zhang, S Liu, H Zhao, S Wu, L Chen, C Ma, H Zhao
    Arthritis Res. Ther., 2020;22(1):99.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. NFAT-Specific Inhibition by dNP2-VIVITAmeliorates Autoimmune Encephalomyelitisby Regulation of Th1 and Th17
    Authors: HG Lee, LK Kim, JM Choi
    Mol Ther Methods Clin Dev, 2020;16(0):32-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  7. Serum amyloid A-mediated inflammasome activation of microglial cells in cerebral ischemia
    Authors: J Yu, H Zhu, S Taheri, W Mondy, L Bonilha, GS Magwood, D Lackland, RJ Adams, MS Kindy
    J. Neurosci., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA Standard
  8. Acute transient cognitive dysfunction and acute brain injury induced by systemic inflammation occur by dissociable IL-1-dependent mechanisms
    Authors: DT Skelly, ÉW Griffin, CL Murray, S Harney, C O'Boyle, E Hennessy, MA Dansereau, A Nazmi, L Tortorelli, JN Rawlins, DM Bannerman, C Cunningham
    Mol. Psychiatry, 2019;24(10):1533-1548.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  9. Phlda3 regulates beta cell survival during stress
    Authors: M Bensellam, JY Chan, K Lee, MV Joglekar, AA Hardikar, T Loudovaris, HE Thomas, JC Jonas, DR Laybutt
    Sci Rep, 2019;9(1):12827.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Interleukin-1? Promotes Schwann Cells De-Differentiation in Wallerian Degeneration via the c-JUN/AP-1 Pathway
    Authors: G Chen, X Luo, W Wang, Y Wang, F Zhu, W Wang
    Front Cell Neurosci, 2019;13(0):304.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: Tissue Culture
  11. Increased ILC3s associated with higher levels of IL-1? aggravates inflammatory arthritis in mice lacking phagocytic NADPH oxidase
    Authors: TY Chan, CL Yen, YF Huang, PC Lo, PA Nigrovic, CY Cheng, WZ Wang, SY Wu, CC Shieh
    Eur. J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  12. 5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives as inhibitors of full-length RORγt
    Authors: C Lao, X Zhou, H Chen, F Wei, Z Huang, C Bai
    Bioorg. Chem., 2019;90(0):103077.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  13. Differential Roles of Dendritic Cells in Expanding CD4 T Cells in Sepsis
    Authors: S Darkwah, N Nago, MG Appiah, PK Myint, E Kawamoto, M Shimaoka, EJ Park
    Biomedicines, 2019;7(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Estrogen receptor ? in T cells suppresses follicular helper T cell responses and prevents autoimmunity
    Authors: DH Kim, HJ Park, HS Park, JU Lee, C Ko, MC Gye, JM Choi
    Exp. Mol. Med., 2019;51(4):41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Pathogenic function of bystander-activated memory-like CD4+ T cells in autoimmune encephalomyelitis
    Authors: HG Lee, JU Lee, DH Kim, S Lim, I Kang, JM Choi
    Nat Commun, 2019;10(1):709.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis
    Authors: S Das, D Bar-Sagi
    Oncogene, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  17. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
    Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
    Sci Rep, 2019;9(1):4034.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf
    Authors: D Pham, CE Moseley, M Gao, D Savic, CJ Winstead, M Sun, BL Kee, RM Myers, CT Weaver, RD Hatton
    Cell Rep, 2019;29(5):1203-1220.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
    Authors: K Yasuda, Y Kitagawa, R Kawakami, Y Isaka, H Watanabe, G Kondoh, T Kohwi-Shig, S Sakaguchi, K Hirota
    Nat Commun, 2019;10(1):549.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Potential Novel Prediction of TMJ-OA: MiR-140-5p Regulates Inflammation Through Smad/TGF-? Signaling
    Authors: W Li, S Zhao, H Yang, C Zhang, Q Kang, J Deng, Y Xu, Y Ding, S Li
    Front Pharmacol, 2019;10(0):15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Responses of perivascular macrophages to circulating lipopolysaccharides in the subfornical organ with special reference to endotoxin tolerance
    Authors: S Morita-Tak, K Nakahara, S Hasegawa-I, A Isonishi, K Tatsumi, H Okuda, T Tanaka, M Kitabatake, T Ito, A Wanaka
    J Neuroinflammation, 2019;16(1):39.
    Species: Mouse
    Sample Types: Protein
    Applications: Specificity Control
  22. Memory-like Liver Natural Killer Cells are Responsible for Islet Destruction in Secondary Islet Transplantation
    Authors: Y Saeki, K Ishiyama, N Ishida, Y Tanaka, H Ohdan
    Sci Rep, 2019;9(1):1022.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Frontline Science: Induction of experimental autoimmune encephalomyelitis mobilizes Th17-promoting myeloid derived suppressor cells to the lung
    Authors: JD Glenn, C Liu, KA Whartenby
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. NCR- group 3 innate lymphoid cells orchestrate IL-23/IL-17 axis to promote hepatocellular carcinoma development
    Authors: Y Liu, Y Song, D Lin, L Lei, Y Mei, Z Jin, H Gong, Y Zhu, B Hu, Y Zhang, L Zhao, HY Teo, J Qiu, W Jiang, C Dong, D Wu, Y Huang, H Liu
    EBioMedicine, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  25. A20 as an immune tolerance factor can determine islet transplant outcomes
    Authors: NW Zammit, SN Walters, KL Seeberger, PJ O'Connell, GS Korbutt, ST Grey
    JCI Insight, 2019;4(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. ? Cell Hypoxia-Inducible Factor-1? Is Required for the Prevention of Type 1 Diabetes
    Authors: A Lalwani, J Warren, D Liuwantara, WJ Hawthorne, PJ O'Connell, FJ Gonzalez, RA Stokes, J Chen, DR Laybutt, ME Craig, MM Swarbrick, C King, JE Gunton
    Cell Rep, 2019;27(8):2370-2384.e6.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  27. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing
    Authors: S Mahmoudi, E Mancini, L Xu, A Moore, F Jahanbani, K Hebestreit, R Srinivasan, X Li, K Devarajan, L Prélot, CE Ang, Y Shibuya, BA Benayoun, ALS Chang, M Wernig, J Wysocka, MT Longaker, MP Snyder, A Brunet
    Nature, 2019;574(7779):553-558.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  28. Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by IL-1Ra
    Authors: DX Ji, LH Yamashiro, KJ Chen, N Mukaida, I Kramnik, KH Darwin, RE Vance
    Nat Microbiol, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  29. Dengue Virus Infection Activates Interleukin-1beta to Induce Tissue Injury and Vascular Leakage
    Authors: P Pan, Q Zhang, W Liu, W Wang, Z Yu, Z Lao, W Zhang, M Shen, P Wan, F Xiao, MA Shereen, W Zhang, Q Tan, Y Liu, X Liu, K Wu, Y Liu, G Li, J Wu
    Front Microbiol, 2019;10(0):2637.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  30. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
    Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
    Neurobiol. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  31. Interleukin-37 Treatment of Mice with Metabolic Syndrome Improves Insulin Sensitivity and Reduces Pro-inflammatory Cytokine Production in Adipose Tissue
    Authors: DB Ballak, S Li, G Cavalli, JL Stahl, IW Tengesdal, JA van Diepen, V Kluck, B Swartzwelt, T Azam, CJ Tack, R Stienstra, T Mandrup-Po, DR Seals, CA Dinarello
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  33. STAT-3-independent production of IL-17 by mouse innate-like ?? T cells controls ocular infection
    Authors: AJ St Leger, AM Hansen, H Karauzum, R Horai, CR Yu, A Laurence, KD Mayer-Barb, P Silver, R Villasmil, C Egwuagu, SK Datta, RR Caspi
    J. Exp. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
    Authors: G Meyer Zu H, D Przybylski, MA Schramm, C Wang, A Schnell, Y Lee, R Sobel, A Regev, VK Kuchroo
    Immunity, 2018;48(3):556-569.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Role of IL-23 signaling in the progression of premalignant oral lesions to cancer
    Authors: B Caughron, Y Yang, MRI Young
    PLoS ONE, 2018;13(4):e0196034.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
    Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
    Mol Metab, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Administration of cytokine-induced myeloid-derived suppressor cells ameliorates renal fibrosis in diabetic mice
    Authors: CC Hsieh, CL Lin, JT He, M Chiang, Y Wang, YC Tsai, CH Hung, PJ Chang
    Stem Cell Res Ther, 2018;9(1):183.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Spleen-derived classical monocytes mediate lung ischemia-reperfusion injury through IL-1?
    Authors: HM Hsiao, R Fernandez, S Tanaka, W Li, JH Spahn, S Chiu, M Akbarpour, D Ruiz-Perez, Q Wu, C Turam, D Scozzi, T Takahashi, HP Luehmann, V Puri, GRS Budinger, AS Krupnick, AV Misharin, KJ Lavine, Y Liu, AE Gelman, A Bharat, D Kreisel
    J. Clin. Invest., 2018;128(7):2833-2847.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Salient type 1 interleukin 1 receptor expression in peripheral non-immune cells
    Authors: A Song, L Zhu, G Gorantla, O Berdysz, SA Amici, M Guerau-de-, KM Madalena, JK Lerch, X Liu, N Quan
    Sci Rep, 2018;8(1):723.
    Species: Mouse
    Sample Types:
    Applications: In Vivo
  40. TGF?1 signaling sustains aryl hydrocarbon receptor (AHR) expression and restrains the pathogenic potential of TH17 cells by an AHR-independent mechanism
    Authors: KA de Lima, PB Donate, J Talbot, M Davoli-Fer, RS Peres, TM Cunha, JC Alves-Filh, FQ Cunha
    Cell Death Dis, 2018;9(11):1130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. REV-ERB? Regulates TH17 Cell Development and Autoimmunity
    Authors: M Amir, S Chaudhari, R Wang, S Campbell, SA Mosure, LB Chopp, Q Lu, J Shang, OB Pelletier, Y He, C Doebelin, MD Cameron, DJ Kojetin, TM Kamenecka, LA Solt
    Cell Rep, 2018;25(13):3733-3749.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Colitis Promotes a Pathological Condition of the Liver in the Absence of Foxp3+ Regulatory T Cells
    Authors: F Mathies, N Steffens, D Kleinschmi, F Stuhlmann, FJ Huber, U Roy, T Meyer, M Luetgehetm, M von Peters, O Seiz, J Herkel, C Schramm, RA Flavell, N Gagliani, C Krebs, U Panzer, Z Abdullah, T Strowig, T Bedke, S Huber
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  43. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018;7(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  44. Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4
    Authors: R Kolb, P Kluz, ZW Tan, N Borcherdin, N Bormann, A Vishwakarm, L Balcziak, P Zhu, BS Davies, F Gourronc, LZ Liu, X Ge, BH Jiang, K Gibson-Cor, A Klingelhut, NS Tan, Y Zhu, FS Sutterwala, X Shen, W Zhang
    Oncogene, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. The group VIA calcium-independent phospholipase A2 and NFATc4 pathway mediates IL-1β-induced expression of chemokines CCL2 and CXCL10 in rat fibroblasts
    Authors: H Kuwata, C Yuzurihara, N Kinoshita, Y Taki, Y Ikegami, S Washio, Y Hirakawa, E Yoda, T Aiuchi, H Itabe, Y Nakatani, S Hara
    FEBS J., 2018;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  46. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  47. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
    Authors: JJ Seeley, RG Baker, G Mohamed, T Bruns, MS Hayden, SD Deshmukh, DE Freedberg, S Ghosh
    Nature, 2018;559(7712):114-119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses
    Authors: CN Berger, VF Crepin, TI Roumelioti, JC Wright, N Serafini, M Pevsner-Fi, L Yu, E Elinav, JP Di Santo, JS Choudhary, G Frankel
    PLoS Pathog., 2018;14(10):e1007406.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Ibrutinib suppresses LPS-induced neuroinflammatory responses in BV2 microglial cells and wild-type mice
    Authors: HY Nam, JH Nam, G Yoon, JY Lee, Y Nam, HJ Kang, HJ Cho, J Kim, HS Hoe
    J Neuroinflammation, 2018;15(1):271.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA (Standard)
  50. IL-23R Signaling Plays No Role in Myocardial Infarction
    Authors: E Engelowski, NF Modares, S Gorressen, P Bouvain, D Semmler, C Alter, Z Ding, U Flögel, J Schrader, H Xu, PA Lang, J Fischer, DM Floss, J Scheller
    Sci Rep, 2018;8(1):17078.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Cutting Edge: IL-1? and Not IL-1? Drives IL-1R1-Dependent Neonatal Murine Sepsis Lethality
    Authors: JT Benjamin, DJ Moore, C Bennett, R van der Me, A Royce, R Loveland, JL Wynn
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  52. The Ror1 receptor tyrosine kinase plays a critical role in regulating satellite cell proliferation during regeneration of injured muscle
    Authors: K Kamizaki, R Doi, M Hayashi, T Saji, M Kanagawa, T Toda, SI Fukada, HH Ho, ME Greenberg, M Endo, Y Minami
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1
    Authors: G Fu, Q Xu, Y Qiu, X Jin, T Xu, S Dong, J Wang, Y Ke, H Hu, X Cao, D Wang, H Cantor, X Gao, L Lu
    J. Exp. Med., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. TNF? drives mitochondrial stress in POMC neurons in obesity
    Authors: CX Yi, M Walter, Y Gao, S Pitra, B Legutko, S Kälin, C Layritz, C García-Các, M Bielohuby, M Bidlingmai, SC Woods, A Ghanem, KK Conzelmann, JE Stern, M Jastroch, MH Tschöp
    Nat Commun, 2017;8(0):15143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells
    Authors: C Wang, CX Xu, Y Alippe, C Qu, J Xiao, E Schipani, R Civitelli, Y Abu-Amer, G Mbalaviele
    Sci Rep, 2017;7(1):4880.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs
    Authors: MX Li, HL Zheng, Y Luo, JG He, W Wang, J Han, L Zhang, X Wang, L Ni, HY Zhou, ZL Hu, PF Wu, Y Jin, LH Long, H Zhang, G Hu, JG Chen, F Wang
    Mol. Psychiatry, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  57. IL-33 receptor ST2 regulates the cognitive impairments associated with experimental cerebral malaria
    Authors: F Reverchon, S Mortaud, M Sivoyon, I Maillet, A Laugeray, J Palomo, C Montécot, A Herzine, S Meme, W Meme, F Erard, B Ryffel, A Menuet, VFJ Quesniaux
    PLoS Pathog., 2017;13(4):e1006322.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Transcription factor NFAT5 promotes macrophage survival in rheumatoid arthritis
    Authors: S Choi, S You, D Kim, SY Choi, HM Kwon, HS Kim, D Hwang, YJ Park, CS Cho, WU Kim
    J. Clin. Invest, 2017;127(3):954-969.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  59. Prolactin blocks the expression of receptor activator of nuclear factor ?B ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis
    Authors: MG Ledesma-Co, N Adán, G Ortiz, M Solís-Guti, F López-Barr, G Martínez d, C Clapp
    Arthritis Res. Ther., 2017;19(1):93.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  60. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
    Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
    J. Nutr. Biochem, 2017;44(0):11-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. The IL-1RI Co-Receptor TILRR (FREM1�Isoform 2) Controls Aberrant Inflammatory Responses and Development of Vascular Disease
    Authors: SA Smith, AO Samokhin, M Alfadi, EC Murphy, D Rhodes, WML Holcombe, E Kiss-Toth, RF Storey, SP Yee, SE Francis, EE Qwarnstrom
    JACC Basic Transl Sci, 2017;2(4):398-414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
    Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
    Cell Death Discov, 2017;3(0):16097.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
    Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
    J. Allergy Clin. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. IL-1? and IL-23 Promote Extrathymic Commitment of CD27(+)CD122(-) ?? T Cells to ??T17 Cells
    Authors: A Muschaweck, F Petermann, T Korn
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Anti-inflammatory effects of a traditional Korean medicine: Ojayeonjonghwan
    Authors: SY Nam, KY Kim, MH Kim, JB Jang, SY Rah, HJ Chae, JM Lee, HM Kim, HJ Jeong
    Pharm Biol, 2017;55(1):1856-1862.
    Species: Mouse
    Sample Types:
    Applications: ELISA (Standard)
  66. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  67. A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain
    Authors: H Makino, S Seki, Y Yahara, S Shiozawa, Y Aikawa, H Motomura, M Nogami, K Watanabe, T Sainoh, H Ito, N Tsumaki, Y Kawaguchi, M Yamazaki, T Kimura
    Sci Rep, 2017;7(1):16983.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis
    Authors: L Franchi, I Monteleone, LY Hao, MA Spahr, W Zhao, X Liu, K Demock, A Kulkarni, CA Lesch, B Sanchez, L Carter, I Marafini, X Hu, O Mashadova, M Yuan, JM Asara, H Singh, CA Lyssiotis, G Monteleone, AW Opipari, GD Glick
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Intestinal fungi contribute to development of alcoholic liver disease
    Authors: AM Yang, T Inamine, K Hochrath, P Chen, L Wang, C Llorente, S Bluemel, P Hartmann, J Xu, Y Koyama, T Kisseleva, MG Torralba, K Moncera, K Beeri, CS Chen, K Freese, C Hellerbran, SM Lee, HM Hoffman, WZ Mehal, G Garcia-Tsa, EA Mutlu, A Keshavarzi, GD Brown, SB Ho, R Bataller, P Stärkel, DE Fouts, B Schnabl
    J. Clin. Invest., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro
    Authors: QH Wang, SW Lv, YY Guo, JX Duan, SY Dong, QS Wang, FM Yu, H Su, HX Kuang
    Evid Based Complement Alternat Med, 2017;2017(0):8134321.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. TNF-? promotes extracellular vesicle release in mouse astrocytes through glutaminase
    Authors: K Wang, L Ye, H Lu, H Chen, Y Zhang, Y Huang, JC Zheng
    J Neuroinflammation, 2017;14(1):87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. The Role of Inflammation in ?-cell Dedifferentiation
    Authors: TM Nordmann, E Dror, F Schulze, S Traub, E Berishvili, C Barbieux, M Böni-Schne, MY Donath
    Sci Rep, 2017;7(1):6285.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. The symbiotic bacterial surface factor polysaccharide A on Bacteroides fragilis inhibits IL-1?-induced inflammation in human fetal enterocytes via toll receptors 2 and 4
    Authors: F Jiang, D Meng, M Weng, W Zhu, W Wu, D Kasper, WA Walker
    PLoS ONE, 2017;12(3):e0172738.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  74. Selective Induction of Homeostatic Th17 Cells in the Murine Intestine by Cholera Toxin Interacting with the Microbiota
    Authors: Q Zhao, SN Harbour, R Kolde, IJ Latorre, HM Tun, TR Schoeb, H Turner, JJ Moon, E Khafipour, RJ Xavier, CT Weaver, CO Elson
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Balanced Bcl-3 expression in murine CD4(+) T cells is required for generation of encephalitogenic Th17 cells
    Authors: IA Mufazalov, J Kuschmann, D Andruszews, J Masri, LA Gabriel, P Adams, S Reissig, N Hövelmeyer, A Waisman
    Eur. J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. G-CSF Receptor Blockade Ameliorates Arthritic Pain and Disease
    Authors: MC Lee, JA McCubbin, AD Christense, DP Poole, P Rajasekhar, T Lieu, NW Bunnett, S Garcia-Car, A Erickson, SM Brierley, R Saleh, A Achuthan, AJ Fleetwood, RL Anderson, JA Hamilton, AD Cook
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  77. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
    Authors: Shweta Pasi
    J Biol Chem, 2016;291(23):12358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. A Critical Role for P2X7 Receptor-Induced VCAM-1 Shedding and Neutrophil Infiltration during Acute Lung Injury
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Guanine nucleotide exchange factor RABGEF1 regulates keratinocyte-intrinsic signaling to maintain skin homeostasis
    Authors: Stephen J Galli
    J. Clin. Invest., 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Early gene activation initiates neuroinflammation prior to VSV neuroinvasion: Impact on antiviral responses and sleep
    Authors: Richard P Ciavarra
    J. Neuroimmunol, 2016;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  81. Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
    Authors: LN Guthrie, K Abiraman, ES Plyler, NT Sprenkle, SA Gibson, BC McFarland, R Rajbhandar, AL Rowse, EN Benveniste, GP Meares
    J. Biol. Chem., 2016;291(30):15830-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. TLR4-Upregulated IL-1? and IL-1RI Promote Alveolar Macrophage Pyroptosis and Lung Inflammation through an Autocrine Mechanism
    Sci Rep, 2016;6(0):31663.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  83. HSP60 plays a regulatory role in IL-1beta-induced microglial inflammation via TLR4-p38 MAPK axis.
    Authors: Swaroop S, Sengupta N, Suryawanshi A, Adlakha Y, Basu A
    J Neuroinflammation, 2016;13(1):27.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Pharmacologic modulation of ROR?t translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis
    Sci Rep, 2016;6(0):37977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Platelets Guide Leukocytes to Their Sites of Extravasation
    PLoS Biol, 2016;14(5):e1002459.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  86. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence
    Nature, 2016;535(7612):440-3.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. SLAM-associated protein favours the development of iNKT2 over iNKT17 cells
    Authors: Marie-Laure Michel
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Overexpression of Glutamate Decarboxylase in Mesenchymal Stem Cells Enhances Their Immunosuppressive Properties and Increases GABA and Nitric Oxide Levels
    PLoS ONE, 2016;11(9):e0163735.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
    Sci Rep, 2016;6(0):39075.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  90. IL-1? is an innate immune sensor of microbial proteolysis
    Authors: CN LaRock, J Todd, DL LaRock, J Olson, AJ O'Donoghue, AA Robertson, MA Cooper, HM Hoffman, V Nizet
    Sci Immunol, 2016;1(2):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis
    Sci Rep, 2016;6(0):39075.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  92. Epidermal RAF prevents allergic skin disease
    Elife, 2016;5(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells
    J Immunol, 2016;196(11):4731-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. A novel TLR2 agonist from Bordetella pertussis is a potent adjuvant that promotes protective immunity with an acellular pertussis vaccine.
    Authors: Dunne A, Mielke L, Allen A, Sutton C, Higgs R, Cunningham C, Higgins S, Mills K
    Mucosal Immunol, 2015;8(3):607-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Testosterone suppresses hepatic inflammation by the downregulation of IL-17, CXCL-9, and CXCL-10 in a mouse model of experimental acute cholangitis.
    Authors: Schwinge D, Carambia A, Quaas A, Krech T, Wegscheid C, Tiegs G, Prinz I, Lohse A, Herkel J, Schramm C
    J Immunol, 2015;194(6):2522-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. IkappaBNS regulates murine Th17 differentiation during gut inflammation and infection.
    Authors: Annemann M, Wang Z, Plaza-Sirvent C, Glauben R, Schuster M, Ewald Sander F, Mamareli P, Kuhl A, Siegmund B, Lochner M, Schmitz I
    J Immunol, 2015;194(6):2888-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Interleukin 1 type 1 receptor restore: a genetic mouse model for studying interleukin 1 receptor-mediated effects in specific cell types.
    Authors: Liu X, Yamashita T, Chen Q, Belevych N, Mckim D, Tarr A, Coppola V, Nath N, Nemeth D, Syed Z, Sheridan J, Godbout J, Zuo J, Quan N
    J Neurosci, 2015;35(7):2860-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  98. Inflammasome activation contributes to interleukin-23 production in response to Clostridium difficile.
    Authors: Cowardin C, Kuehne S, Buonomo E, Marie C, Minton N, Petri W
    MBio, 2015;6(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
    Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
    Nat Med, 2015;21(4):363-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
    Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
    J Immunol, 2015;195(9):4415-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.
    Authors: Basu R, Whitley S, Bhaumik S, Zindl C, Schoeb T, Benveniste E, Pear W, Hatton R, Weaver C
    Nat Immunol, 2015;16(3):286-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Direct conversion of fibroblasts into functional astrocytes by defined transcription factors.
    Authors: Caiazzo M, Giannelli S, Valente P, Lignani G, Carissimo A, Sessa A, Colasante G, Bartolomeo R, Massimino L, Ferroni S, Settembre C, Benfenati F, Broccoli V
    Stem Cell Reports, 2015;4(1):25-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Interleukin-1beta enhances FasL-induced caspase-3/-7 activity without increasing apoptosis in primary mouse hepatocytes.
    Authors: Lutz A, Sanwald J, Thomas M, Feuer R, Sawodny O, Ederer M, Borner C, Humar M, Merfort I
    PLoS ONE, 2014;9(12):e115603.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. IFN-gamma or IFN-alpha ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.
    Authors: Tamiya H, Terao M, Takiuchi T, Nakahara M, Sasaki Y, Katayama I, Yoshikawa H, Iwai K
    J Immunol, 2014;192(8):3793-804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. ICAM-2 facilitates luminal interactions between neutrophils and endothelial cells in vivo.
    Authors: Halai, Krishma, Whiteford, James, Ma, Bin, Nourshargh, Sussan, Woodfin, Abigail
    J Cell Sci, 2014;127(0):620-9.
  106. Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.
    Authors: Jin, Shijie, Sonobe, Yoshifum, Kawanokuchi, Jun, Horiuchi, Hiroshi, Cheng, Yi, Wang, Yue, Mizuno, Tetsuya, Takeuchi, Hideyuki, Suzumura, Akio
    PLoS ONE, 2014;9(12):e115981.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
    Authors: Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh-hora M, Kodama T, Tanaka S, Bluestone J, Takayanagi H
    Nat Med, 2014;20(1):62-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis.
    Authors: Glenn J, Smith M, Calabresi P, Whartenby K
    Stem Cells, 2014;32(10):2744-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
    Authors: Steelman A, Smith R, Welsh C, Li J
    J Biol Chem, 2014;288(33):23776-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics.
    Authors: Hahn W, Kuzmicic J, Burrill J, Donoghue M, Foncea R, Jensen M, Lavandero S, Arriaga E, Bernlohr D
    Am J Physiol Endocrinol Metab, 2014;306(9):E1033-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. IL-18 regulates melanoma VLA-4 integrin activation through a Hierarchized sequence of inflammatory factors.
    Authors: Valcarcel M, Carrascal T, Crende O, Vidal-Vanaclocha F
    J Invest Dermatol, 2014;134(2):470-80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha.
    Authors: Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T
    J Immunol, 2014;193(3):1459-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis.
    Authors: Jana M, Mondal S, Jana A, Pahan K
    Immunology, 2014;141(4):549-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion.
    Authors: Bakker P, Butter L, Claessen N, Teske G, Sutterwala F, Florquin S, Leemans J
    Am J Pathol, 2014;184(7):2013-22.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  115. Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-alpha and interleukin-1beta but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain.
    Authors: Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R
    J Biol Chem, 2014;289(22):15621-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Glimepiride reduces CD14 expression and cytokine secretion from macrophages.
    Authors: Ingham V, Williams A, Bate C
    J Neuroinflammation, 2014;11(0):115.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: ELISA (Standard)
  117. Role of Blimp-1 in programing Th effector cells into IL-10 producers.
    Authors: Neumann C, Heinrich F, Neumann K, Junghans V, Mashreghi M, Ahlers J, Janke M, Rudolph C, Mockel-Tenbrinck N, Kuhl A, Heimesaat M, Esser C, Im S, Radbruch A, Rutz S, Scheffold A
    J Exp Med, 2014;211(9):1807-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
    Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
    Elife, 2014;3(0):e02809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
    Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
    Mucosal Immunol, 2014;7(4):818-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. A novel in vitro model to study pericytes in the neurovascular unit of the developing cortex.
    Authors: Zehendner, Christop, Wedler, Hannah E, Luhmann, Heiko J
    PLoS ONE, 2013;8(11):e81637.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  121. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013;190(8):4196-204.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. In vivo processing of CXCL5 (LIX) by matrix metalloproteinase (MMP)-2 and MMP-9 promotes early neutrophil recruitment in IL-1beta-induced peritonitis.
    Authors: Song J, Wu C, Zhang X, Sorokin L
    J Immunol, 2013;190(1):401-10.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo
  123. PI3-kinase gamma promotes Rap1a-mediated activation of myeloid cell integrin alpha4beta1, leading to tumor inflammation and growth.
    Authors: Schmid M, Franco I, Kang S, Hirsch E, Quilliam L, Varner J
    PLoS ONE, 2013;8(4):e60226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production.
    Authors: Lee S, Lee K, Yi S, Kook S, Lee J
    PLoS ONE, 2013;8(12):e80873.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  125. Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
    Authors: Bruchard M, Mignot G, Derangere V, Chalmin F, Chevriaux A, Vegran F, Boireau W, Simon B, Ryffel B, Connat J, Kanellopoulos J, Martin F, Rebe C, Apetoh L, Ghiringhelli F
    Nat Med, 2012;19(1):57-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33.
    J. Exp. Med., 2012;209(8):1505-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice.
    Authors: Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algul H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP
    J. Clin. Invest., 2012;122(5):1758-63.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  128. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Age-Dependent Neuroimmune Modulation of IGF-1R in the Traumatic Mice.
    Authors: Zhao H, Zhao X, Cao X, Wu G
    Immun Ageing, 2012;9(1):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression.
    Authors: Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, Zhang L, Liu X, Yen Y, Lai L, Forman BM, Xu Z, Xu R, Huang W
    Mol. Endocrinol., 2012;26(5):775-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Laminin-411 Is a Vascular Ligand for MCAM and Facilitates TH17 Cell Entry into the CNS.
    Authors: Flanagan K, Fitzgerald K, Baker J
    PLoS ONE, 2012;7(7):e40443.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Interleukin-23-mediated inflammation in Pseudomonas aeruginosa pulmonary infection.
    Authors: Dubin PJ, Martz A, Eisenstatt JR, Fox MD, Logar A, Kolls JK
    Infect. Immun., 2012;80(1):398-409.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  133. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
    Authors: Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S
    J. Exp. Med., 2012;209(6):1219-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  134. Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.
    Authors: Petri B, Kaur J, Long EM, Li H, Parsons SA, Butz S, Phillipson M, Vestweber D, Patel KD, Robbins SM, Kubes P
    Blood, 2011;117(3):942-52.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  135. Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
    Authors: Ma Y, Aymeric L, Locher C, Mattarollo SR, Delahaye NF, Pereira P, Boucontet L, Apetoh L, Ghiringhelli F, Casares N, Lasarte JJ, Matsuzaki G, Ikuta K, Ryffel B, Benlagha K, Tesniere A, Ibrahim N, Dechanet-Merville J, Chaput N, Smyth MJ, Kroemer G, Zitvogel L
    J. Exp. Med., 2011;208(3):491-503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Insulin-like Growth Factor 1-mediated Hyperthermia Involves Anterior Hypothalamic Insulin Receptors.
    Authors: Sanchez-Alavez M, Osborn O, Tabarean IV
    J. Biol. Chem., 2011;286(17):14983-90.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  137. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  138. XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases.
    Authors: Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L
    MAbs, 2011;3(1):49-60.
    Species: Mouse
    Sample Types: Buffer
    Applications: Binding Assay
  139. Arcuate nucleus proopiomelanocortin neurons mediate the acute anorectic actions of leukemia inhibitory factor via gp130.
    Authors: Grossberg AJ, Scarlett JM, Zhu X, Bowe DD, Batra AK, Braun TP, Marks DL
    Endocrinology, 2010;151(2):606-16.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  140. Tim3 binding to galectin-9 stimulates antimicrobial immunity.
    Authors: Jayaraman P, Sada-Ovalle I, Beladi S, Anderson AC, Dardalhon V, Hotta C, Kuchroo VK, Behar SM
    J. Exp. Med., 2010;207(11):2343-54.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  141. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice.
    Authors: Cho JS, Pietras EM, Garcia NC, Ramos RI, Farzam DM, Monroe HR, Magorien JE, Blauvelt A, Kolls JK, Cheung AL, Cheng G, Modlin RL, Miller LS
    J. Clin. Invest., 2010;120(5):1762-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
    Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
    Brain Behav. Immun., 2010;24(5):747-58.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  143. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
    J. Virol., 2010;84(24):12703-12.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  144. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis.
    Authors: Chou RC, Kim ND, Sadik CD
    Immunity, 2010;33(2):266-78.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  145. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Caspase-1, caspase-8, and calpain are dispensable for IL-33 release by macrophages.
    Authors: Ohno T, Oboki K, Kajiwara N, Morii E, Aozasa K, Flavell RA, Okumura K, Saito H, Nakae S
    J. Immunol., 2009;183(12):7890-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. The role of interleukin-6 in lipopolysaccharide-induced fever by mechanisms independent of prostaglandin E2.
    Authors: Nilsberth C, Elander L, Hamzic N, Norell M, Lonn J, Engstrom L, Blomqvist A
    Endocrinology, 2009;150(4):1850-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  148. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice.
    Authors: Mizutani N, Nabe T, Yoshino S
    J. Immunol., 2009;183(6):4039-46.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  149. The critical role of kinase activity of interleukin-1 receptor-associated kinase 4 in animal models of joint inflammation.
    Authors: Koziczak-Holbro M, Littlewood-Evans A, Pollinger B, Kovarik J, Dawson J, Zenke G, Burkhart C, Muller M, Gram H
    Arthritis Rheum., 2009;60(6):1661-71.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  150. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
    Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
    Nat. Med., 2009;15(10):1170-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages.
    Authors: Martin U, Scholler J, Gurgel J, Renshaw B, Sims JE, Gabel CA
    J. Immunol., 2009;183(6):4021-30.
    Species: N/A
    Sample Types: N/A
    Applications: Western Blot
  152. Regulation of agouti-related protein messenger ribonucleic acid transcription and peptide secretion by acute and chronic inflammation.
    Authors: Scarlett JM, Zhu X, Enriori PJ, Bowe DD, Batra AK, Levasseur PR, Grant WF, Meguid MM, Cowley MA, Marks DL
    Endocrinology, 2008;149(10):4837-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  153. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008;58(11):3510-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. IL-1F5 mediates anti-inflammatory activity in the brain through induction of IL-4 following interaction with SIGIRR/TIR8.
    Authors: Costelloe C, Watson M, Murphy A, McQuillan K, Loscher C, Armstrong ME, Garlanda C, Mantovani A, O'Neill LA, Mills KH, Lynch MA
    J. Neurochem., 2008;105(5):1960-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  155. Induction of IL-33 expression and activity in central nervous system glia.
    Authors: Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT
    J. Leukoc. Biol., 2008;84(3):631-43.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.
    Authors: Bujak M, Dobaczewski M, Chatila K, Mendoza LH, Li N, Reddy A, Frangogiannis NG
    Am. J. Pathol., 2008;173(1):57-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model.
    Authors: Wu CC, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson DA, Guiney DG, Corr M
    Cell. Immunol., 2008;251(2):78-85.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  158. Effects of i.c.v. administration of interleukin-1 on sleep and body temperature of interleukin-6-deficient mice.
    Authors: Olivadoti MD, Opp MR
    Neuroscience, 2008;153(1):338-48.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  159. Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages.
    Authors: Kang YJ, Kim SO, Shimada S, Otsuka M, Seit-Nebi A, Kwon BS, Watts TH, Han J
    Nat. Immunol., 2007;8(6):601-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Protection of CD8+ T cells from activation-induced cell death by IL-18.
    Authors: Li W, Kashiwamura S, Ueda H, Sekiyama A, Okamura H
    J. Leukoc. Biol., 2007;82(1):142-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.
    Authors: Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW
    J. Leukoc. Biol., 2007;83(2):361-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  162. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
    Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
    J. Immunol., 2006;177(3):1967-74.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  163. The Myc-dependent angiogenic switch in tumors is mediated by interleukin 1beta.
    Authors: Shchors K, Shchors E, Rostker F, Lawlor ER, Brown-Swigart L, Evan GI
    Genes Dev., 2006;20(18):2527-38.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Modification of MyD88 mRNA splicing and inhibition of IL-1beta signaling in cell culture and in mice with a 2'-O-methoxyethyl-modified oligonucleotide.
    Authors: Vickers TA, Zhang H, Graham MJ, Lemonidis KM, Zhao C, Dean NM
    J. Immunol., 2006;176(6):3652-61.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  165. A new RXR agonist, HX630, suppresses intimal hyperplasia in a mouse blood flow cessation model.
    Authors: Haraguchi G, Suzuki J, Kosuge H, Ogawa M, Koga N, Muto S, Itai A, Kagechika H, Shudo K, Isobe M
    J. Mol. Cell. Cardiol., 2006;41(5):885-92.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
    Authors: Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
    Inflamm. Res., 2006;55(11):457-64.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  167. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury.
    Authors: Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L962-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system.
    Authors: Ching S, He L, Lai W, Quan N
    Brain Behav. Immun., 2005;19(2):127-37.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  169. TLR-2 is upregulated and mobilized to the hepatocyte plasma membrane in the space of Disse and to the Kupffer cells TLR-4 dependently during acute endotoxemia in mice.
    Authors: Ojaniemi M, Liljeroos M, Harju K, Sormunen R, Vuolteenaho R, Hallman M
    Immunol. Lett., 2005;102(2):158-68.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  170. Involvement of monocyte chemoattractant protein-1, macrophage inflammatory protein-1alpha and interleukin-1beta in Wallerian degeneration.
    Authors: Perrin FE, Lacroix S, Aviles-Trigueros M, David S
    Brain, 2005;128(0):854-66.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  171. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005;302(1):172-81.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  172. Selective macrophage suppression during sepsis.
    Authors: Ellaban E, Bolgos G, Remick D
    Cell. Immunol., 2004;231(1):103-11.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)

FAQs

  1. Does IL-1 beta induce NO in smooth muscle?

    • Yes it does, based on the literature.

  2. Can Recombinant Mouse IL-1 beta/IL-1F2 Protein (Catalog # 401-ML) be used in rat or human cells?

    • Bioactivity of Recombinant Mouse IL-1 beta Protein (Catalog # 401-ML) has only been evaluated using mouse cells. We offer both Recombinant Human IL-1 beta Protein (Catalog # 201-IL) and Recombinant Rat IL-1 beta Protein (Catalog # 501-RL) that we recommend for use in human and rat assay systems.

View all Proteins and Enzyme FAQs

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Reviews for Recombinant Mouse IL-1 beta/IL-1F2 Protein

Average Rating: 4.9 (Based on 7 Reviews)

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Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 10/05/2020
Application: In vitro bioactivity in cell culture

Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 03/17/2020
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Good for Th17 Differentiation

Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 03/06/2020
Application: In vivo study

Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 01/15/2020
Application: In vitro bioactivity in cell culture

Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 12/15/2017
Application: Inflammatory stimulant
Reason for Rating: Primary mouse fibroblasts were treated with IL1b for 24 hours. The supernatant was collected and analyzed for IL-6.



Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 08/02/2017
Application: In vitro bioactivity in cell culture

Recombinant Mouse IL-1 beta/IL-1F2 Protein
By Anonymous on 01/13/2016
Application: Apoptosis assay
Reason for Rating: I have a good apoptosis results

I treat the IL-1 beta with IFN-gamma in beta-Tc3 cells.
Cell death rate is almost 30% for 48 hrs.