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TACS Annexin V-FITC Apoptosis Detection Kit

Catalog #: 4830-250-K
76 Citations 1 Review Datasheet / COA / SDS
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4830-01-K
4830-250-K
TACS Annexin V-FITC Apoptosis Detection Kit_4830-250-K
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TACS Annexin V-FITC Apoptosis Detection Kit Summary

Allows rapid, specific, and quantitative identification of apoptosis in individual cells when using flow cytometry.

Why Use the TACS Annexin V-FITC Apoptosis Detection Kit?

Annexin V is a calcium-dependent phospholipid binding protein that can be used to bind Phosphatidylserine(PS) during an early apoptosis event where the PS becomes exposed at the cell surface.

The TACS Annexin V-FITC Apoptosis Detection Kit is supplied with an optimized Binding Buffer and propidium iodide. Propidium iodide may be used on unfixed samples to determine the population of cells that have lost membrane integrity, allowing discrimination between apoptotic and necrotic (or late apoptotic) cells.

Kit Contents

• Annexin V FITC
• 10X Binding Buffer
• Propidium Iodide

Specifications

Shipping Conditions
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended on the product label.
Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Species
Multi-species

Limitations

For research use only. Not for diagnostic use.

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Scientific Data

Flow Cytometry TACS Annexin V-FITC Apoptosis Detection Kit_4830-250-K View Larger

Detection of Apoptotic Dexamethasone-treated Thymocytes by Annexin V Staining. Thymocytes were left untrated (left) or treated with 100 nM Dexamethasone for 15.5 hours (right) and then stained using Annexin V-FITC and propidium iodide provided in the TACS Annexin V-FITC Apoptosis Detection Kit (Catalog # 4830-250-K). The combination of Annexin V-FITC and propidium iodide allows for the distinction between early apoptotic cells (Annexin V-FITC positive), late apoptotic and/or necrotic cells (Annexin V-FITC and propidium iodide positive), and viable cells (unstained). Analysis courtesy of Dr. C.M. Knudson, Howard Hughes Medical Institute, St. Louis, MO.

Citations for TACS Annexin V-FITC Apoptosis Detection Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

76 Citations: Showing 1 - 10
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  1. Metallodrugs against Breast Cancer: Combining the Tamoxifen Vector with Platinum(II) and Palladium(II) Complexes
    Authors: A Kazimir, B Schwarze, P Lönnecke, S Jela?a, S Mijatovi?, D Maksimovi?, E Hey-Hawkin
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    Peptides, 2023;165(0):171013.  2023
  3. Transcriptomics-Based Investigation of Molecular Mechanisms Underlying Apoptosis Induced by ZnO Nanoparticles in Human Diffuse Large B-Cell Lymphoma
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    International Journal of Nanomedicine, 2022;17(0):2261-2281.  2022-01-01
  4. Icariin inhibits epithelial mesenchymal transition of renal tubular epithelial cells via regulating the miR-122-5p/FOXP2 axis in diabetic nephropathy rats
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    Journal of pharmacological sciences, 2022;148(2):204-213.  2022-01-01
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    Authors: Z Cai, H Guo, J Qian, W Liu, Y Li, L Yuan, Y Zhou, R Lin, X Xie, Q Yang, G Wu, Q Li, L Zhao, F Liu, J Wang, W Lu
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  20. The Effects of Muscle Cell Aging on Myogenesis
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    International Journal of Molecular Sciences, 2021;22(7):.  2021-01-01
  21. LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma
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    Cell Death & Disease, 2021;12(4):347.  2021-01-01
  22. Generation of mature compact ventricular cardiomyocytes from human pluripotent stem cells
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    Nature Communications, 2021;12(1):3155.  2021-01-01
  23. Au2phen and Auoxo6, Two Dinuclear Oxo-Bridged Gold(III) Compounds, Induce Apoptotic Signaling in Human Ovarian A2780 Cancer Cells
    Authors: G Gorini, F Magherini, T Fiaschi, L Massai, M Becatti, A Modesti, L Messori, T Gamberi
    Biomedicines, 2021;9(8):.  2021-01-01
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    Authors: H Lu, X Sun, M Jia, F Sun, J Zhu, X Chen, K Chen, K Jiang
    Oxidative Medicine and Cellular Longevity, 2021;2021(0):5527137.  2021-01-01
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    Cell Death & Disease, 2021;12(2):167.  2021-01-01
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    Disease Models & Mechanisms, 2021;14(10):.  2021-01-01
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    International immunopharmacology, 2021;100(0):108066.  2021-01-01
  29. X-ray repair cross-complementing protein 1 (XRCC1) loss promotes beta-lapachone -induced apoptosis in pancreatic cancer cells
    Authors: Y Zheng, H Zhang, Y Guo, Y Chen, H Chen, Y Liu
    BMC Cancer, 2021;21(1):1234.  2021-01-01
  30. MLK4 regulates DNA damage response and promotes triple-negative breast cancer chemoresistance
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    Cell Death & Disease, 2021;12(12):1111.  2021-01-01
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    Cell Reports, 2021;37(9):110060.  2021-01-01
  32. Polymer Coated Oncolytic Adenovirus to Selectively Target Hepatocellular Carcinoma Cells
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    Pharmaceutics, 2021;13(7):.  2021-01-01
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    BioMed Research International, 2021;2021(0):6633297.  2021-01-01
  34. Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition
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  35. Non pharmacological high-intensity ultrasound treatment of human dermal fibroblasts to accelerate wound healing
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    Scientific Reports, 2021;11(1):2465.  2021-01-01
  36. Sensitivity of Papilloma Virus-Associated Cell Lines to Photodynamic Therapy with Curcumin-Loaded Liposomes
    Authors: G Ambreen, L Duse, I Tariq, U Ali, S Ali, SR Pinnapired, M Bette, U Bakowsky, R Mandic
    Cancers (Basel), 2020;12(11):.  2020-01-01
  37. Apatinib ameliorates doxorubicin-induced migration and cancer stemness of osteosarcoma cells by inhibiting Sox2 via STAT3 signalling
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    J Orthop Translat, 2020;22(0):132-141.  2020-01-01
  38. Protein tyrosine phosphatase 1B as a therapeutic target for Graves' orbitopathy in an in vitro model
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    PLoS ONE, 2020;15(8):e0237015.  2020-01-01
  39. Exosomal lncRNA H19 promotes the progression of hepatocellular carcinoma treated with Propofol via miR-520a-3p/LIMK1 axis
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    Cancer Med, 2020;0(0):.  2020-01-01
  40. Evaluation of immunomodulatory effects of Boswellia sacra essential oil on T-cells and dendritic cells
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    BMC Complement Med Ther, 2020;20(1):352.  2020-01-01
  41. Vulnerability of drug-resistant EML4-ALK rearranged lung cancer to transcriptional inhibition
    Authors: AR Paliouras, M Buzzetti, L Shi, IJ Donaldson, P Magee, S Sahoo, HS Leong, M Fassan, M Carter, G Di Leva, MG Krebs, F Blackhall, CM Lovly, M Garofalo
    EMBO Mol Med, 2020;0(0):e11099.  2020-01-01
  42. IGF2 autocrine-mediated IGF1R activation is a clinically relevant mechanism of osimertinib resistance in lung cancer
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    Mol. Cancer Res., 2020;0(0):.  2020-01-01
  43. Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    Cell Rep, 2020;31(11):107764.  2020-01-01
  44. Indole-6-Carboxaldehyde Isolated from Sargassum thunbergii (Mertens) Kuntze Prevents Oxidative Stress-Induced Cellular Damage in V79-4 Chinese Hamster Lung Fibroblasts through the Activation of the Nrf2/HO-1 Signaling Pathway
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TACS Annexin V-FITC Apoptosis Detection Kit
By Anonymous on 02/24/2021
TACS Annexin V-FITC Apoptosis Detection Kit 4830-250-K