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UNC 2399

Catalog #: 4930
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4930/1
UNC 2399 | EZH2 Inhibitor
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Description: Biotinylated UNC 1999 (Cat.No. 4904)

Chemical Name: 1-Isopropyl-N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[6-[4-[41-oxo-45-[(3aS,4aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-4,7,10,13,16,19,22,25,28,31,34,37-dodecaoxa-40-azapentatetracontan-1oyl]piperazin-1-yl]pyridin-3-yl]-1H-indazole-4-carboxamide

Purity: ≥95%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Additional Information Product Datasheets Calculators

Biological Activity

UNC 2399 is a biotinylated UNC 1999 (Cat.No. 4904, IC50 = 17 nM). Enriches lysine methyltransferase EZH2 from HEK293T cells.

Negative control also avilable.

Technical Data

M.Wt:
1353.66
Formula:
C67H104N10O17S
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This compound is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the UNC 1999 probe summary on the SGC website.

Product Datasheets

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Citation for UNC 2399

The citations listed below are publications that use Tocris products. Selected citations for UNC 2399 include:

1 Citation: Showing 1 - 1

  1. An orally bioavailable chemical probe of the lysine methyltransferases EZH2 and EZH1.
    Authors: Konze Et al.
    ACS.Chem.Biol.  2013;8:1324

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