VDM 11 (in Tocrisolve™ 100)

Biological Activity

VDM 11, pure oil dissolved in ethanol and Tocrisolve Control also available.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. The uptake by cells of 2-arachidonoylglycerol, an endogenous agonist of cannabinoid receptors.
   Bisogno et al.
   Eur.J.Biochem., 2001;268:1982
2. The activity of anandamide at vanilloid VR1 receptors requires facilitated transport across the cell membrane and is limited by intracellular metabolism.
   De Petrocellis et al.
   J.Biol.Chem., 2001;276:12856
3. Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: inhibitors of anandamide uptake with negligible capsaicin-like activity.
   De Petrocellis et al.
   FEBS Lett., 2000;483:52
4. Experimental Parkinsonism alters endocannabinoid degradation: implications for striatal glutamatergic transmission.
   Gubellini et al.
   J.Neurosci., 2002;22:6900

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