Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Gln-Met-Asp(OMe)-fluoromethylketone
Biological ActivityCaspase-3 inhibitor. Inhibits MG 132-induced small cell lung cancer cell death in vitro.
(Modifications: Asp-1 = Z-Asp(OMe), Asp-4 = (OMe)-fluoromethylketone)
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For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Characterization of NF-κB expression in Hodgkin's disease: inhibition of constitutively expressed NF-κB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells.
Izban et al.
Differential response to MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents.
Bang et al.
Alterations in protein kinase C activity and processing during zinc deficiency-induced cell death.
Chou et al.
Citation for Z-DQMD-FMK
The citations listed below are publications that use Tocris products. Selected citations for Z-DQMD-FMK include:
1 Citation: Showing 1 - 1
HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation.
Authors: Allam Et al.
PLoS One 2018;13:e0194185
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