7 results for "5-HT1A Small Molecules and Peptides" in Products

5-HT1A Small Molecules and Peptides

5-HT1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin(1A) receptors, including 5-HT1A, belong to the family of G protein-coupled receptors and are implicated in the generation and modulation of various cognitive, behavioral and developmental functions. A relationship between 5-HT1A receptors and serotonin transporter (5-HTT) is also suggested by the pathophysiology of depression and the mechanism of action of antidepressants.

Endogenous 5-HT receptor agonist

Alternate Names: 5-Hydroxytryptamine,5-HT
Chemical Name: 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride
Purity: ≥98%
Endogenous 5-HT receptor agonist
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5-HT1A, 5-HT1B and 5-HT1D agonist

Alternate Names: GR 43175
Chemical Name: 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate
Purity: ≥99%
5-HT1A, 5-HT1B and 5-HT1D agonist
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5-HT1A and 5-HT1B agonist

Chemical Name: 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
Purity: ≥99%
5-HT1A and 5-HT1B agonist
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Selective 5-HT1A agonist

Alternate Names: TVX Q 7821
Chemical Name: 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide
Purity: ≥99%
Selective 5-HT1A agonist
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Selective 5-HT1A partial agonist

Alternate Names: SM-3997
Chemical Name: (3aR,4S,7R,7aS)-rel-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione hydrochloride
Purity: ≥98%
Selective 5-HT1A partial agonist
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High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist

Chemical Name: 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone
Purity: ≥99%
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
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Potent 5-HT1A partial agonist and SSRI; antidepressant

Alternate Names: EMD 68843,SB 659746A
Chemical Name: 5-[4-[4-(5-Cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-2-benzofurancarboxamide hydrochloride
Purity: ≥98%
Potent 5-HT1A partial agonist and SSRI; antidepressant
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