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24 results for "additional-rtk-inhibitors&view=expanded" in Products

c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation

Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-methoxyphenyl]-N'-[1-(2-thiazolyl)ethyl]urea
Purity: ≥97%
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
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VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3

Alternate Names: Semaxinib
Chemical Name: 3-[(3,5-Dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-2H-indol-2-one
Purity: ≥98%
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
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Potent CSF-1R inhibitor

Chemical Name: N-[5-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-2-pyridinyl]-6-(trifluoromethyl)-3-pyridinemethanamine
Purity: ≥98%
Potent CSF-1R inhibitor
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Potent and selective DDR1 inhibitor; orally bioavailable

Chemical Name: 4-Ethyl-N-[3-[(4-methyl-1-piperazinyl)methyl]-5-(trifluoromethyl)phenyl]-3-(2-pyrazolo[1,5-a]pyrimidin-6-ylethynyl)benzamide
Purity: ≥98%
Potent and selective DDR1 inhibitor; orally bioavailable
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Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor

Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide
Purity: ≥98%
Potent colony-stimulating factor 1 receptor (CSF-1R) tyroine kinase inhibitor
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EGFR kinase inhibitor. Also estrogen and PPARγ ligand

Chemical Name: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
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Potent RET inhibitor

Chemical Name: 1-(1-Methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Purity: ≥98%
Potent RET inhibitor
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Selective cFMS kinase inhibitor; orally bioavailable

Chemical Name: 5-[[3-Methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]-2,4-pyrimidinediamine
Purity: ≥98%
Selective cFMS kinase inhibitor; orally bioavailable
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Potent Mer kinase inhibitor

Chemical Name: 2-(Butylamino)-4-[(trans-4-hydroxycyclohexyl)amino]-N-[[4-(1H-imidazol-1-yl)phenyl]methyl]-5-pyrimidinecarboxamide
Purity: ≥98%
Potent Mer kinase inhibitor
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Potent Tie2 inhibitor

Chemical Name: [3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur
Purity: ≥98%
Potent Tie2 inhibitor
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