8 results for "alpha-2A Adrenergic R/ADRA2A" in Products
alpha-2A Adrenergic R/ADRA2A Products
Alpha-2-adrenergic receptors, including ADRA2A, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both ADRA2A and ADRA2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
α2A agonist
| Chemical Name: | [(2,6-Dichlorophenyl)acetyl]guanidine hydrochloride |
| Purity: | ≥98% |
α2 agonist. Also I1 ligand
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino-2-imidazoline hydrochloride |
| Purity: | ≥98% |
α2 agonist
| Chemical Name: | 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline |
α2 agonist. Water-soluble form of UK 14,304 (Cat. No. 0425)
| Chemical Name: | 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline tartrate |
| Purity: | ≥98% |
Potent, highly selective α2 agonist. Active isomer of medetomidine (Cat. No. 5160)
| Alternate Names: | d-Medetomidine hydrochloride |
| Chemical Name: | 4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Selective α2 agonist
| Alternate Names: | Azepexole |
| Chemical Name: | 6-Ethyl-5,6,7,8-tetrahydro-4H-oxazolo[4,5-d]azepin-2-amine dihydrochloride |
| Purity: | ≥98% |
α2 agonist
| Chemical Name: | 5-(Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine hydrochloride |
| Purity: | ≥98% |
Potent and highly selective α2 agonist
| Chemical Name: | 4-[1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole hydrochloride |
| Purity: | ≥98% |