8 results for "alpha-2C Adrenergic R/ADRA2C" in Products
alpha-2C Adrenergic R/ADRA2C Products
Alpha-2-adrenergic receptors, including ADRA2C, are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C receptors that have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Mouse studies have revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The ADRA2A subtype inhibited transmitter release at high stimulation frequencies, whereas the ADRA2C subtype modulated neurotransmission at lower levels of nerve activity.
Selective α2 antagonist
| Chemical Name: | 17α-Hydroxyyohimban-16α-carboxylic acid methyl ester hydrochloride |
| Purity: | ≥98% |
Potent, selective α2D antagonist
| Chemical Name: | 2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Potent and non-selective β antagonist; also potent α1 antagonist
| Alternate Names: | BM 14190 |
| Chemical Name: | 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol |
| Purity: | ≥98% |
Selective α2 antagonist
| Chemical Name: | 5-(2-Ethyl-2,3-dihydro-1H-indene-2-yl)-1H-imidazole hydrochloride |
| Purity: | ≥98% |
Potent and selective α2 antagonist
| Chemical Name: | 6-Chloro-N-methyl-2,3,4,5-tetrahydro-1-H-3-benzazepine hydrochloride |
| Purity: | ≥98% |
Potent and selective α2C antagonist
| Chemical Name: | N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinamine dihydrochloride |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% |
Potent and selective adrenergic α2B antagonist
| Chemical Name: | 1-[2-[[[3-(3,5-Dimethyl-4-isoxazolyl)imidazo[1,2-a]pyridin-7-yl]carbonyl]amino]ethyl]-4-(methylamino)pyridinium chloride |
| Purity: | ≥98% |
