8 results for "Antiangiogenic Compounds" in Products

Antiangiogenic Compounds

Antiangiogenic agents are compounds which prevent angiogenesis in vitro and/or in vivo. Angiogenesis inhibitors may be endogenous or synthetic; others are obtained from diet, for example resveratrol.

Thioredoxin-1 inhibitor

Alternate Names: IV-2
Chemical Name: 2-[(1-Methylpropyl)dithio]-1H-imidazole
Purity: ≥98%
Thioredoxin-1 inhibitor
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Binds cereblon; also TNF-α synthesis inhibitor

Chemical Name: N-(2,6-dioxo-3-piperidinyl)phthalimide
Purity: ≥98%
Binds cereblon; also TNF-α synthesis inhibitor
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Potent and selective α1β1 inhibitor

Purity: ≥95%
Potent and selective α1β1 inhibitor
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Cyclooxygenase inhibitor

Chemical Name: 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol
Purity: ≥98%
Cyclooxygenase inhibitor
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MCT inhibitor; decreases glycoloysis

Chemical Name: 2-Cyano-3-(4-hydroxyphenyl)-2-propenoic acid
Purity: ≥98%
MCT inhibitor; decreases glycoloysis
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PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor

Chemical Name: 2-(Methylthio)-6-[4-[5-[[3-(trifluoromethyl)phenyl]amino]-1H-1,2,4-triazol-3-yl]phenoxy]-4-pyrimidinamine
Purity: ≥98%
PDGFRβ, B-Raf, c-Raf, FLT3 and KIT inhibitor
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Potent VEGFR inhibitor; also inhibits other RTKs

Alternate Names: Cabozantinib,BMS 907351
Chemical Name: N-[4-[(6,7-Dimethoxy-4-quinolinyl)oxy]phenyl]-N-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
Purity: ≥98%
Potent VEGFR inhibitor; also inhibits other RTKs
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DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis

Alternate Names: NSC125066
Purity: ≥90%
DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis
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