10 results for "Cdk9" in Products

Cdk9 Products

CDK9 (PITALRE) (also known as cyclin-dependent kinase 9, Serine/threonine-protein kinase PITALRE, C-2K and Cell division cycle 2-like protein kinase 4) is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cyc...

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Cdk inhibitor; potently inhibits cdk9; also inhibits MK2

Chemical Name: 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride
Purity: ≥98%
Cdk inhibitor; potently inhibits cdk9; also inhibits MK2
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Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

Alternate Names: BMS-387032
Chemical Name: N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide
Purity: ≥98%
Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9
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Potent and selective Cdk9 Degrader (PROTAC®)

Chemical Name: N-(5-(((5-(tert-Butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(14-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-2-oxo-6,9,12-trioxa-3-azatetradecyl)piperidine-4-carboxamide
Purity: ≥98%
Application of THAL SNS 032 in MOLT-4 cells
(2)
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Potent and selective ATP-competitive CDK9 inhibitor

Chemical Name: 4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile
Purity: ≥97%
Potent and selective ATP-competitive CDK9 inhibitor
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Selective HyT-based degrader of the CDK9-cyclin T1 complex

Chemical Name: N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-1-[[2-[[2-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]acetyl]amino]ethyl]sulfonyl]-4-piperidinecarboxamide
Purity: ≥98%
Selective HyT-based degrader of the CDK9-cyclin T1 complex
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Cdk inhibitor; potently inhibits cdk2 and cdk9

Alternate Names: L 86-8275
Chemical Name: 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride
Purity: ≥98%
Cdk inhibitor; potently inhibits cdk2 and cdk9
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Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9

Chemical Name: 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine
Purity: ≥98%
Cdk inhibitor; potently inhibits cdk1, 2, 5 and 9
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Inhibits RNA polymerase

Chemical Name: 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Purity: ≥95%
Inhibits RNA polymerase
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Cdk inhibitor

Alternate Names: CYC 202,Seliciclib
Chemical Name: (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol
Purity: ≥98%
Cdk inhibitor
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GSK-3β inhibitor; also inhibits cdks

Chemical Name: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity: ≥98%
GSK-3β inhibitor; also inhibits cdks
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