231 results for "Chk2" in Products

Chk2 Products

The Chk2 checkpoint kinase is an integral member of the signaling cascade that controls cell cycle checkpoints. In response to genotoxic insults Chk2 is phosphorylated by ATM or ATM-related kinases. Phosphorylation of Chk2 T68 promotes the formation of Chk2 oligomers. Oligomerization is a critical event in the activation of the Chk2 kinase as it is required for phosphorylation of additional Chk2 residues that lead to full activation and signaling to downstream effectors.

Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins

Reactivity: Human
Detection of human protein kinase phosphorylation in A549 Cell Line.
(4)
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Reactivity: Human, Mouse, Rat, Canine
Details: Mouse IgG1 Monoclonal Clone #OTI5C4
Applications: IHC, WB, Flow, ICC/IF, IP, + 1 More
Western Blot: Chk2 Antibody (OTI5C4)Azide and BSA Free [NBP2-71688]
(9)
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Reactivity: Human, Mouse, Rat, Canine
Details: Mouse IgG1 Monoclonal Clone #OTI5C4
Applications: IHC, WB, Flow, ICC/IF, IP
Western Blot: Chk2 Antibody (OTI5C4) [NBP1-47695]
(10)
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Reactivity: Human
Details: Mouse IgG2a Kappa Monoclonal Clone #4B7
Applications: IHC, WB, ELISA, ICC/IF
Western Blot: Chk2 Antibody (4B7) [H00011200-M01]
(5)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL9440
Applications: IHC, WB, ICC/IF
Western Blot: Chk2 Antibody (CL9440) [NBP2-88933]
(8)
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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #CL9440
Applications: IHC, WB, ICC/IF
Chk2 Antibody (CL9440) - Azide and BSA Free Immunohistochemistry-Paraffin: Chk2 Antibody [NBP3-44069]
(8)
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Reactivity: Human, Mouse
Details: Mouse IgG1 Monoclonal Clone #8F12
Applications: WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: Chk2 Antibody (8F12) [NB100-500]
(3)
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Reactivity: Human
Source: Sf 9 (baculovirus)
Accession #: NM_007194
Applications: Bioactivity
Recombinant Human Active Chk2 Protein SDS-PAGE
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: IHC, WB, ICC/IF
Immunocytochemistry/ Immunofluorescence: Chk2 Antibody [NBP1-90024]
(3)
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Reactivity: Human
Assay Range: 312-20000 pg/mL
Applications: ELISA
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Potent and selective allosteric inhibitor of Wip1 phosphatase

Chemical Name: 5-[[(5-Chloro-2-methyl-3-pyridinyl)amino]methyl]-N-[(1S)-1-(cyclopentylmethyl)-2-(cycloprpylamino)-2-oxoethyl]-2-thiophenecarboxamide
Purity: ≥98%
Potent and selective allosteric inhibitor of Wip1 phosphatase
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Reactivity: Human
Details: Rabbit IgG Polyclonal
Applications: KO, WB, ICC/IF
Western Blot: Chk2 [p Thr68] Antibody [NBP3-13076]
(3)
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