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171 results for "cIAP-2/HIAP-1" in Products
cIAP-2/HIAP-1 Products
cIAP-2 (also known as MIHC and HIAP-1) is a member of the inhibitor of apoptosis (IAP) family of proteins that inhibit the proteolytic activity of mature caspases. cIAP-2 has 3 BIR (baculovirus inhibitor of apoptosis) domains, a RING finger domain, and a caspase recruitment domain (CARD). cIAP-2 inhibits caspases through the direct interaction of its BIR domain with the active caspase. Caspase activity may be restored through interactions with the Reaper like motif on mitochondrial proteins such as SMAC/Diablo or HtrA2/Omi. cIAP-2 is reported to be cleaved by HtrA2/Omi.
| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | Q13489 |
| Applications: | Inhibition Activity |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #315301 |
| Applications: | WB, Simple Western |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB, Simple Western |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Simple Western |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB, Simple Western |
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| Reactivity: | Human |
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| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
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| Chemical Name: | 3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide |
| Purity: | ≥97% |
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| Reactivity: | Human |
| Applications: | AC |
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| Reactivity: | Human |
| Applications: | AC |
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| Chemical Name: | (R)-1-((S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)pyrrolidine-2-carboxamido)-2,3-dihydro-1H-inden-4-yl sulfurofluoridate |
| Purity: | ≥95% |
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| Chemical Name: | (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-phenoxy-N-((R)-1,2,3,4-tetrahydronaphthalen-1-yl)pyrrolidine-2-carboxamide |
| Purity: | ≥97% |
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| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #OTI1A9 |
| Applications: | WB, Flow, CyTOF-ready |
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| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR2173 |
| Applications: | IHC, WB, ICC/IF, IP |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #315304 |
| Applications: | IHC, WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
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| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC, WB |
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