14 results for "Class II Histone Deacetylases Inhibitors Small Molecules and Peptides" in Products

Class II Histone Deacetylases Inhibitors Small Molecules and Peptides

HDAC classification

Superfamily Family Class Subclass Protein (human)
Arginase/deacetylase superfamily Histone deacetylase family Class I HDAC1, HDAC2, HDAC3, HDAC8
Class II Class IIa HDAC4, HDAC5, HDAC7, HDAC9
ClassIIb HDAC6, HDAC10
Class IV HDAC11
Deoxyhypusine synthase like NAD/FAD-binding domain superfamily Sir2 regulator family Class III I SIRT1, SIRT2, SIRT3
II SIRT4
III SIRT5
IV SIRT6, SIRT7

Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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Potent histone deacetylase inhibitor

Chemical Name: (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity: ≥95%
Potent histone deacetylase inhibitor
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HDAC6 inhibitor; inhibits α-tubulin deacetylation

Chemical Name: N-[4-[(2R,4R,6S)-4-[[(4,5-Diphenyl-2-oxazolyl)thio]methyl]-6-[4-(hydroxymethyl)phenyl]-1,3-dioxan-2-yl]phenyl]-N'-hydroxyoctanediamide
Purity: ≥96%
HDAC6 inhibitor; inhibits α-tubulin deacetylation
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Class I and II HDAC inhibitor

Alternate Names: Vorinostat
Chemical Name: N-Hydroxy-N'-phenyloctanediamide
Purity: ≥98%
Class I and II HDAC inhibitor
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Histone deacetylase inhibitor

Alternate Names: 4-PB,Sodium phenylbutyrate
Chemical Name: 4-Phenylbutyric acid, sodium salt
Purity: ≥98%
Histone deacetylase inhibitor
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Histone deacetylase inhibitor

Chemical Name: Butanoic acid sodium salt
Histone deacetylase inhibitor
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High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic

Chemical Name: 1,2-dihydro-4-hydroxy-5-methoxy-N,1-dimethyl-2-oxo-N-[4-(trifluoromethyl)phenyl]-3-quinolinecarboxamide
Purity: ≥98%
High affinity HDAC4 negative allosteric modulator; also binds S100A9; antiangiogenic
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Potent class I and IIb HDAC inhibitor

Chemical Name: 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide
Purity: ≥98%
Potent class I and IIb HDAC inhibitor
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Histone deacetylase inhibitor

Alternate Names: ITF 2357
Chemical Name: [6-[(Diethylamino)methyl]-2-naphthalenyl]methyl-N-[4-[(hydroxyamino)carbonyl]phenyl]carbamate hydrochloride
Purity: ≥98%
Histone deacetylase inhibitor
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Dual histone deacetylase (HDAC) 6/8 inhibitor

Chemical Name: N1-Hydroxy-N3-(2-phenylethyl)-1,3-benzenedicarboxamide
Purity: ≥98%
Dual histone deacetylase (HDAC) 6/8 inhibitor
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Highly potent and selective HDAC2 inhibitor

Chemical Name: Ethyl N-[4-oxo-4-[(2-phenylethyl)amino]butyl]carbamate
Purity: ≥98%
Highly potent and selective HDAC2 inhibitor
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Pan-histone deacetylase inhibitor

Chemical Name: (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
Purity: ≥98%
Pan-histone deacetylase inhibitor
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Potent and selective HDAC class IIa inhibitor

Chemical Name: N-((R)-1-((S)-2-Methylpyrrolidin-1-yl)propan-2-yl)-4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
Purity: ≥98%
Potent and selective HDAC class IIa inhibitor
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Potent and selective HDAC4 Degrader (PROTAC®)

Chemical Name: (2S,4R)-1-((3R,26S)-26-(tert-Butyl)-3-methyl-1,24-dioxo-5-propyl-1-(4-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)phenyl)-10,13,16,19,22-pentaoxa-2,5,25-triazaheptacosan-27-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥98%
Potent and selective HDAC4 Degrader (PROTAC®)
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