5 results for "EAAT2/GLT1 Small Molecules and Peptides" in Products

EAAT2/GLT1 Small Molecules and Peptides

GLT1 is the major glial glutamate transporter that takes up more than 90% of glutamate from the synapse. GLT1b is a splice variant that contains 11 unique amino acids at the C-terminus that encode a PDZ binding domain. GLT1b was initially believed to be the neuronal isoform of GLT1, but it now appears that GLT1b is localized to astrocytes in the no...

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Selective non-transportable inhibitor of EAATs

Chemical Name: DL-threo-β-Benzyloxyaspartic acid
Purity: ≥98%
Selective non-transportable inhibitor of EAATs
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Potent, non-substrate EAAT2 inhibitor

Chemical Name: N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine
Purity: ≥98%
Potent, non-substrate EAAT2 inhibitor
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Potent competitive inhibitor of L-glutamate uptake

Chemical Name: 7-Chloro-4-hydroxyquinoline-2-carboxylic acid
Purity: ≥98%
Potent competitive inhibitor of L-glutamate uptake
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EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake

Chemical Name: (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid
EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
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Potent and selective positive allosteric modulator of EAAT2

Chemical Name: 3-((4-Cyclohexylpiperazin-1-yl)(1-phenethyl-1H-tetrazol-5-yl)methyl)-6-methoxyquinolin-2(1H)-one
Purity: ≥98%
Potent and selective positive allosteric modulator of EAAT2
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